Gene 94984.m00181 (T.vaginalis)

94984.m00181

Species: T.vaginalis
Alias: 94984.m00181, TvagK0690
External Links:
Annotation:

Classification

Group: Other
Family: NEK
Subfamily: NEK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
94984.m00181.AA Protein None 436 None Fasta, JSON
94984.m00181.kin_dom Protein Kinase Domain None 255 None Fasta, JSON

Protein domain

Protein domains of 94984.m00181.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 94984.m00181.AA NEK 4-258 45 7.2e-133 447.71 In-house 1-286 (286) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-286/286
Sequence Identity: 45% (129 aa)

FKIVKEIGRGGYGRALLVRSLNSNDL-----KVVKAMNLTGMTQEAKDTAF-REVEILSTLKHTNIIRYRGCTKQKR--NLYILMDYAD-GGDLSQA---
..|.|.||.| .|.. .||. . ..       | | .|...|... |. |   || ||. ||| ||..|. .   .    |.| |.|.. ||||.|    
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

IKRQ--GVVFFSEDQILDWFVQICLAMKYLHDR-----KILHRDMKPQNVFLSS-GN---IVKLGDFGIAKTLEHTGDMAKT-SIGTPLYCSPEICVGKK
||.|     .|.|.||.|||.|.|||.||.|||     |||||| ||||.||.. .|   .||.|||||.| |.|| |||.|  .||| | |||.| .|.
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKP

YNTKSDIWSLGCVLYELASL--KRPFTGR--NVAEIMRNVIGK-TPKPIPAQ--YSTELQSLVESMLRKNPDERPSINEIFQMPLI
|| |||||||||||||...|  |.|| .   |  . . ...   ...||| .  ||..||.|...||.|.|..|||.|.|..||.|
YNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase 94984.m00181.AA NEK1 4-258 47 4.4e-122 411.89 In-house 1-276 (276) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-276/276
Sequence Identity: 47% (130 aa)

FKIVKEIGRGGYGRALLVRSLNSNDLKVVKAMNLTGMTQEAKDTAFREVEILSTLKHTNIIRYRGCTKQKRN--LYILMDYADGGDLSQAIKRQ--GVVF
. . | || | .|.|.||..  .. . | |  |.. | .. . .. .|| ||. .|| ||..|.       .  ||| |.|.||||| |.|.||    . 
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGKL

FSEDQILDWFVQICLAMKYLHDRKILHRDMKPQNVFLS--SGN---------------IVKLGDFGIAKTLEHTGDMAKTSIGTPLYCSPEICVGKKYNT
||||||..||.|||||... ||||||||| |.||.||.  ..                .|||||||||..| || . |.| |||| | |||||  | || 
FSEDQIMHWFCQICLALNHIHDRKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPEICQNKPYNN

KSDIWSLGCVLYELASLKRPFTGRNVAEIMRNVIGKTPKPIPAQYSTELQSLVESMLRKNPDERPSINEIFQMPLI
||||||||||||||  ||.|| ..|       ..  |  |||. ||.|||||| .|...||  |||.| | . | |
KSDIWSLGCVLYELCTLKHPFEANNWKNLVLKICQGTYPPIPPHYSYELQSLVSQMFKRNPRHRPSVNQILERPFI
Kinase 94984.m00181.AA NEK8 10-258 38 4.2e-104 298.12 In-house 7-278 (278) Show / Hide 
Range on Protein: 10-258
Range on HMM: 7-278/278
Sequence Identity: 38% (105 aa)

IGRGGYGRALLVRSLNSN--DLKVVKAMNLTGMTQEAKDTAFREVEILSTLKHTNIIRYRGCTKQKRNLYILMDYADGGDLSQAI-KRQGVVFFSED---
.|||  | . | |  . .   | . |  |...|. .  . |  |...|| | | ||| | .       | | | ||||| | | | ..|.  |. |    
VGRGAFGICWLYRRKEDQSHHLVIWKQINMHRMSEKERQMAQNEIQVLSMLQHPNIISYYDHFMEDNTLMIEMEYADGGTLYQMIQHQQNKLFEEERQLK

-------------QILDWFVQICLAMKYLHDRKILHRDMKPQNVFLSSG-NIVKLGDFGIAKTLEHTGDMA--KTSIGTPLYCSPEICVGKKYNTKSDIW
             .||. |.|.|.|  ..|.  ||||| |.||.|.    ..||.|||||.| .     |.  || .|||.| |||.| ||.|| |||.|
QVNHCFNIYFNEQMILWYFFQMCSAVHHMHQHNILHRDLKTQNIFMTRHRMVVKIGDFGISKIMNTKYHMQTTKTVVGTPYYMSPEMCEGKPYNQKSDMW

SLGCVLYELASLKRPFTGRNVAEIMRNVIG-KTPKPIPAQYSTELQSLVESMLRKNPDERPSINEIFQMPLI
.|||||||...||| | . |  ..    .  ..  ||. .|| |. .||.. | . |. |||  .|  |||.
ALGCVLYEMCCLKRAFEASNLPALVWKIMQCRAYEPISDHYSNEMRMLVHNCLQQDPEQRPSASQIMAMPLC
Kinase 94984.m00181.AA NEK4 4-258 44 5.2e-101 341.89 In-house 1-257 (257) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-257/257
Sequence Identity: 44% (114 aa)

FKIVKEIGRGGYGRALLVRSLNSNDLKVVKAMNLTGMTQEAKDTAFREVEILSTLKHTNIIRYRGCTKQKRN--LYILMDYADGGDLSQAIKRQGVVFFS
. ..| .|.| ||   |||.       |.| |.|    .. .  | .|...|| ||| ||. |    .   .  ||| | . .|||| .  |.|   | .
YCHMKVVGKGSYGEVWLVRHRRDKKQYVMKKMFLKNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDLYRKLKQQKNQFLE

EDQILDWFVQICLAMKYLHDRKILHRDMKPQNVFLSSGNIVKLGDFGIAKTLEHTGDMAKTSIGTPLYCSPEICVGKKYNTKSDIWSLGCVLYELASLKR
| |...||||| .|. |.|...|||||.| ||.||   ||.|.|||||.. |.  .||||| |||| | |||.   . |. ||||||||| .||.. || 
EYQVVEWFVQIAMALQYMHEKHILHRDLKTQNIFLTKKNIIKIGDFGISRVLNNHCDMAKTMIGTPYYMSPECFGNRPYDYKSDIWSLGCCVYEMITLKH

PFTGRNVAEIMRNVIGKTPKPIPAQYSTELQSLVESMLRKNPDERPSINEIFQMPLI
 |  ..   ..  .|   | |.| .||..|| ||  || | |..|||| .||||| |
AFDAKDMNSLIYQIIQGQPPPMPPNYSQDLQNLVYQMLEKQPTKRPSIFDIFQMPYI
Kinase 94984.m00181.AA S_TKc 4-258 28 1.4e-91 311.46 SMART 1-231 (231) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-231/231
Sequence Identity: 28% (77 aa)

FKIVKEIGRGGYGRALLVRSLNSNDLKVVKAMNLTGMTQEAKDTAFREVEILSTLKHTNIIRYRGCTKQKRNLYILMDYADG--GDLSQAIKRQGVVF--
..|...||.|..|.  ..|  ... .  .| ..         ... ||..||.  .| ||... ..     .||. |.|.||  ||| . ||..|     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--FSEDQILDWFVQICLAMKYLHDRKILHRDMKPQNVFLSSGNIVKLGDFGIAKTLEHTGDMAKTSIGTPLYCSPEICVGKKYNT-KSDIWSLGCVLYEL
  |.| ..  .. |||.|..|.|...|.||| ||.|..|..   .|..|||.|. |       .| .||| |..||..   .|.. |.|.||.||.|||.
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

ASLKRPFTGRNVAEIMRNVIGKTPKPIPAQYSTELQSLVESMLRKNPDERPSINEIFQ-------MPLI
.. . ||   .........            | |. .... .|.|.|..||.. |..|       .| .
LCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 94984.m00181.AA Pkinase 4-258 27 4.1e-85 293.88 Pfam 1-293 (293) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-293/293
Sequence Identity: 27% (82 aa)

FKIVKEIGRGGYGRALLVRSLNSNDLKVVKAMNLTGMTQEAKDTAFR--EVEILSTLKHTNIIRYRGCTKQKRNLYILMDYADGG----DLSQAIK-RQG
..|.. ||.|..|.  . .  ..... .|| ... .   . . |..|  |..|.  |.| ||.|....   |...|. |.|..||    ||.  |. ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

VVF-FSEDQILDWFVQICLAMKYLHDRKILHRDMKPQNVFLS-SGNI---VKLGDFGIAKTL-EHTGDMAKTSIGTPLYCSPEICV-GKKYNTKSDIWSL
 .| |||... ... ||. ...|.|...|.|||.||.|....  |.|   ||..|||.|| . .  .  ..|  ||| |..||..  |..| .|.|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCVLYELASLKRPFTGR------NVAEIMRNVIG-KTPKPIPAQYS-------------------TELQSLVESMLRKNPDERPSINEIFQMPLI
||.|||... . || |.      .  ...... | ... ..|  .|                    |........|.|.| .||.. .|.| | .
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 94984.m00181.AA NEK2 4-258 32 1.4e-75 253.99 In-house 1-319 (319) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-319/319
Sequence Identity: 32% (105 aa)

FKIVKEIGRGGYGRALLVRSLNSNDLKVVKAMNLTGMTQEAKDTAFREVEILSTLKHTNIIRY--RGCTKQKRNLYILMDYADGGDLSQAIK--RQGVVF
  . ..||.| .||   ||      . | | ..   |.   ..    |. ||. ||| ||.||  .   .|.  ||| | |  |||||| ||  |.   .
YEVLYTIGNGSFGRCRKVRRKSDGKILVWKEICYGHMQEKECQMLVSECNILRQLKHPNIVRYYDWIIDRQNSTLYIVMEYCEGGDLSQMIKKCRKERQY

FSEDQILDWFVQICLAMKYLHD---------------------RKILHRDMKPQNVFLSSGNI-------------------------------------
. |  |.  . |.|.| .  |                      . |||||.|| |.||..                                        
MEEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGKHTILHRDIKPANIFLDYDHNDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQ

--VKLGDFGIAKTLEHTGDMAKTSIGTPLYCSPEICVGKKYNTKSDIWSLGCVLYELASLKRPFTGRNVAEIMRNVIGKTPKPIPAQYSTELQSLVESML
  ||||||| |. |.|    |.| .||| | |||   | ||| ||||||.||..||...|. ||...| |.    . .    .||.|||..|. .. .|.
VVVKLGDFGLARMLNHDTSFAHTFVGTPYYMSPEQMHGQKYNEKSDIWSVGCLIYEMCALHPPFQATNQAQLQEKIKQGHFRRIPYQYSRHLNEIIHFMI

RKNPDERPSINEIFQMPLI
  ..  ||||.|| | |.|
NVDHYHRPSIEEILQHPQI
Kinase 94984.m00181.AA ULK 4-258 27 1.5e-74 254.0 In-house 1-329 (329) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-329/329
Sequence Identity: 27% (90 aa)

FKIVKEIGRGGYGRALLVRSLNS----NDLKVVKAMNLTGMTQEAKDTA--------FREVEILSTLK--------HTNIIRYRGCTKQK--RNLYILMD
. . ...| | .|.    |  ..    | . ..| . .  | |. ..           .|..|. .||        | ||...  ... .   |.|| |.
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YADGGDLSQAIKRQGV--------VFFSEDQILDWFVQICLAMKYLHDRKILHRDMKPQNVFLSSGN------------IVKLGDFGIAKTLEHT---GD
| .||||.| ||...          ..||....  | ||. ..|.||...| |||.||||. .. |.            ..|..||| ||...      .
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

MAKTSI------GTPLYCSPEICV----GKKYN-TKSDIWSLGCVLYELASLKRP----FTGRNVAEIMRNV---------IGKTPKPIP-----AQYST
|..|        ||||| .|.|      .|.|.  |.|||||||..||.   | |    |.  .   |....         | |.|  .|      | | 
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

ELQSLVESMLRKNPDERPSINEIFQMPLI
|...|   || .....| |. |.|..|..
ECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 94984.m00181.AA ULK 4-258 27 3.2e-70 239.59 In-house 1-324 (324) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-324/324
Sequence Identity: 27% (88 aa)

FKIVKEIGRGGYG-RALLVRSLNS---NDLKVVKAMNLTGMTQEAKDTA--------FREVEILSTLK---HTN--IIRYRGCTKQK--RNLYILMDYAD
. . ...| | .|      |  ..   | .  .| ... .| .  ..           .|..|. .||   | |  |...  ... .   |.|| |.| .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGDLSQAIKRQGV-------VFFSEDQILDWFVQICLAMKYLHDRKILHRDMKPQNVFLSSGN------------IVKLGDFGIAKTLEHTG---DMAKT
||||.| ||...         ..||....  | ||| ..|.||...| |||.||||  .. |.            ..|..||| ||...  .   .| .|
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

SI------GTPLYCSPEICV----GKKYN-TKSDIWSLGCVLYELASLKRP----FTGRNVAEIMRNVI-----------GKTPKPIPA---QYSTELQS
        ||||| .|.|      .|.|.  |.|||||||..||.   | |    |.  .   |.. .             . ..|.|    . | |...
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LVESMLRKNPDERPSINEIFQMPLI
|   || .....| |. |||..|..
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 94984.m00181.AA CAMK 9-258 19 2e-69 222.66 In-house 1-425 (425) Show / Hide 
Range on Protein: 9-258
Range on HMM: 1-425/425
Sequence Identity: 19% (82 aa)

EIGRGGYGRALLVRSLNSN------------DLKVVKAMNLTGMT--------------------------QEAKDTAFREVEILST-------LKHTNI
..|||..|   |..  |..                .| .. . ..                          .. ..  .||.||...       |.| ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IRYRG--------------------CTKQKRNLYILM---DYADGG----DLSQAIKRQGV-------------VFFSEDQILDWFVQICLAMKYLHDRK
|.                       . ......|. |   .|..||    || . |...|                |.|..   .| ||| |..|.|...
IKLYEVYEDPHYFKNTNDYETSKQVF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

ILHRDMKPQNVFLSSG-----------------NIVKLGDFGIAKTLEH-----------------------TGDMAKTSIGTPLYCS-PEICVGKK---
| ||| || |. |..                  | .|. ||| |. ...                       .|.. ||. ||| |.. ||.  ||.   
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

-----------YNTKSDIWSLGCVLYELASLKRPFTGR-------------NVAEIMRNVIGKTPKPIPAQYST-----------------------ELQ
           |. |.|.||.|..|| . . . || |              |  |......      .| . |.                       | .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

SLVESMLRKNPDERPSINEIFQMPLI
.|. .||...|..|..| .. . | .
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 94984.m00181.AA STE 4-258 23 6.7e-69 235.21 In-house 1-359 (359) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-359/359
Sequence Identity: 23% (84 aa)

FKIVKEIGRGGYGRALLVRSLN---------------SNDLKVVKAMNLTGMTQ---------------EAKDTAFREVEILSTLK--HTNIIRYRGCTK
......||.|..|   . .  .               ....  .| |||   ..               | ..   .|..|.. ..  | ||..| ||  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

QKR-------NLYILMDYADGGDLSQAIKRQGVVFFS------------EDQILDWFVQICLA-MKYLHDRKILHRDMKPQNVFLSSGNIVKLGDFGIAK
..        .|.| | | ||| |.. ||. . ....            |.||    .||. . ..|||. .| ||| ||.|..|     ||| |||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

TLEH---------------TGD-MAKTSIGTPLYCSPEICVG------KKYNTKSDIWSLGCVLYELASLKRPF-TGRNVAEIMRNVIG-----------
 |..               |.. . .| .||| . .||.  .      |.|.||.|||||||.. |.|  | |. .. .   ...  ..           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---KTPKPIP-------------------AQYSTELQSLVESMLRKNPDERPSINEIFQ--MPLI
   ..| |.|                    ..| |..  ..  |.|.|..||. ..  .   | |
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 94984.m00181.AA Ciliate-E2 4-258 23 3.2e-67 229.64 In-house 1-365 (365) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-365/365
Sequence Identity: 23% (89 aa)

FKIVKEIGRGGYG-----RALLVRSL------------------NSNDLKVVKAMNLTGMTQEAK-DTAFREVE----------ILSTLKHTNIIRYRGC
.|..| ||.|..|     .  .|. .                  . . .. .| |.  .  |  . .  .||..          ||..|.| |||..  |
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

TK--QKRNLYILMDYADGGDLSQAIKRQ----------GVVFFSEDQILDWFVQICL---------------AMKYLHDRK-ILHRDMKPQNVFLSSGNI
 .  .. |.|. |.|..|||| . || .          .   |.| .|.. . ||.                |..||| .. |.||| ||.|...     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

VKLGDFGIAK----------------TLEHTG----------------DMAKTSIGTPLYCSPEICVGKK---------YNTKSDIWSLGCVLYELASLK
.|. |||..|                 .   .                .|..| .||| | .|||  |||         |..|.||||||..|||. . |
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

RPFTGRNVAEIMRNVIGKTPKP-------------IPAQYSTELQSLVES----MLRKNPDERPS-INEIFQMPLI
.||      .|. . |   ..              .. . | | . |       || |.|..|.. ...|.. | .
PPF----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 94984.m00181.AA TyrKc 4-258 22 2.1e-31 111.54 SMART 1-280 (280) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-280/280
Sequence Identity: 22% (66 aa)

FKIVKEIGRGGYG---RALLVRSLNSNDLKV-VKAMNLTGMTQEAKDTAFREVEILSTL--KHTNIIRYRGCTKQK-------RNLYILMDYADGGDLSQ
 .  |..|.| .|   .. .        ..| || ..        .    || .|.. |  .| ||.|  |.  |.         |.|.| |...||| .
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

AIKRQGVVFFSEDQILDWFVQICLAMKYLHDRKILHRDMKPQNVFLSSGNIVKLGDFGIAKTLEHT------GDMAKTS--IGTP--L---YCSPEICVG
 ... .   .. .. |.. .||.  | |||.... |||    |. ......|| .||| .. ...       .|. ...   |.   |    ..||    
YLRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY

KKYNTKSDIWSLGCVLYELASL-KRPFTG-----RNVAEIMRNVIGKTPKPIPAQ--------YSTELQSLVESMLRKNPDERPSINEIFQMPLI
.|..||||.|| | ...|. .. . |  |      . .|....|      |.|.          ..|. .. ..  . .|..||. .||    ..
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 94984.m00181.AA Pkinase_Tyr 49-252 27 1e-28 97.9 Pfam 51-266 (270) Show / Hide 
Range on Protein: 49-252
Range on HMM: 51-266/270
Sequence Identity: 27% (60 aa)

FREVEILSTL-KHTNIIRYRGCTK-QKRN--LYILMDYADGGDLSQAIKRQ--GVVFFSEDQILDWFVQICLAMKYLHDRKILHRDMKPQNVFLSSGNIV
.||..|...| .| ||.|. |.   |..   .|| | |. .|||    ...  .   ..  ..|.. .||. .| ||..... |||    |. ....|.|
MREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVV

KLGDFGIAKTLEHTGDM-AKTSIGTPL---YCSPEICVGKKYNTKSDIWSLGCVLYELASL-KRP-FTGRNVAEIMRNV-IGKTPKPIPAQYSTELQSLV
| .||| |.......    |.. |  |    ..||    .|..||||.|| | ...|. .. . | . |   .|... .       |.|   . |. .| 
KICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLM

ESMLRKNPDERPSINEI
 .  ...|..||.  ||
KQCWHYDPEDRPTFSEI