Gene 94230.m00031 (T.vaginalis)

94230.m00031

Species: T.vaginalis
Alias: TvagK0427, 94230.m00031
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
94230.m00031.AA Protein None 431 None Fasta, JSON
94230.m00031.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 94230.m00031.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH 94230.m00031.AA PH 7-102 16 1.5e-11 45.63 SMART 1-82 (82) Show / Hide 
Range on Protein: 7-102
Range on HMM: 1-82/82
Sequence Identity: 16% (16 aa)

EPLSGYLDKKGKIGIYTKKWATLQGSEFRLFRDDTLNAKELTLNVQETTKIQMESIDSCKFSIETEGSTEPLYFRAPSTESLLQWIHALRSCTYTH
  ..|.| ||.    ..|.|..| .. . ...|.   ..  ......  ....       | | . .    .||...| |.. .|..|...... .
VIKEGWLYKKS-K-RWKKRWFVLFNDCLYYYKDK---KPKGSIPLSDC-TVRE-P----CFEIHH-DR--TYYFQCESEEEMQEWMQAIQKAIHNN
PH 94230.m00031.AA PH 7-100 22 3e-09 36.0 Pfam 1-92 (92) Show / Hide 
Range on Protein: 7-100
Range on HMM: 1-92/92
Sequence Identity: 22% (22 aa)

EPLSGYLDKKGKIGIYTKKWATLQGSEFRLFRDDTLNAKELTLNVQETTKIQMESI--DSCKFSIETEGSTEPLYFRAPSTESLLQWIHALRSCTY
  ..|.| ||||.. . | |..|...   ...||.   .  ......  ..   .   . . | | | .  . .||.|.| |.. .|..|..|. .
VIKEGWLHKKGKRKSWKKRWFVLFNNCLYYYKDDK-YRPKGSIPLSDC-QVTKVPDNKRPHCFQIRT-DR-RTYYFQAESEEEMNDWMQAIQSACR
Kinase 94230.m00031.AA AGC 110-361 30 6.6e-155 403.88 In-house 1-395 (395) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-395/395
Sequence Identity: 30% (122 aa)

FKVLSVLGRGNYGKVMLAEKI------DSGELFAIKSVHKKR-LALAG--KVHTMLSE------------RNTLINAS----------NPFIVK-LFYAF
|..| |.|.| .|||.|..|       |.|...|.| . ||.   .    .|.  ..|            || | ...          .||||| |.|.|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QNATK--FYLVLEYVP---------GG-EMFNYMS---TNGAVPLEDARIYAAE-------IVTALHFLHQ-NDIIYRD-LKPENILLAQDGHIKLTDFG
|. ..   |.|.||.|         || |.| ..     .|  . | ||.||||       || ||..||. ..||.|| |||||||| .||||||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

FAKDLSQSE---------------------------------------------------VTKTFCG--TNEYLAPEVISRVNYGPAVDWWT--LGILLY
..| . ...                                                    |.||||  | ||.|||..    ||.|.|||.  ||.|.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMLFQTTPFFHQNTS----------RMFTRIL------MDPVVFP----------KGADPDVCSLITGLLQKRDRKRYA----------YEDIIKHPFF
|||.  .||...|.            || .|.      ...| ||          .  .|.  .||..||.|  .||            .|.| .||.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 94230.m00031.AA Akt 110-361 42 8.10000000001e-121 387.97 In-house 1-264 (264) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-264/264
Sequence Identity: 42% (113 aa)

FKVLSVLGRGNYGKVMLAEKIDSGELF-AIKSVHKKRLALAGKVHTMLSERNTLINASNPFIVKLFYAFQNATKFYLVLEYVPGGEMFNYMSTNGAVPLE
| .| |||.| .|||.|..| |..... |.|.  |...   ..|   . ||| | .  .||||.| |.||...| |.|..|..||| |....  .  . .
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

DARIYAAEIVTALHFLHQNDIIYRD-LKPENILLAQDGHIKLTDFGFAK-D-LSQSEVTKTFCGTNEYLAPEVISRVNYGPAVDWWT-LGILLYEMLFQT
 || |.|||. |. .||...||||| |||||||. .||||.||||| .| . ... ..||||||| ||||||... . .. |||||. ||...|||..  
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

TPFFHQNTSRMFTRILMDPVVFP--KGADPDVCSLITGLLQKRDRKRYA-----YEDIIKHPFF
 ||..|.  .||  |.. || ||  .  .|.  .||.|||.|   ||        ..|  ||.|
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 94230.m00031.AA SGK 110-361 40 4.6e-116 360.04 In-house 1-283 (283) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-283/283
Sequence Identity: 40% (115 aa)

FKVLSVLGRGNYGKVMLAEKIDS------------------GELFAIKSVHKKRLA-------LAGKVHTMLSER-NTLINASNPFIVKLFYAFQNATKF
|. |.|.| |..|||..... |                   . ..|.|   |.             ..   ..|| . | | . ||||.| ||||...| 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLVLEYVPGGEMFNYMSTNGAVPLEDARIYAAEIVTALHFLHQNDIIYRDLKPENILLAQDGHIKLTDFGFAK-DLSQSEVTKTFCGTNEYLAPEVISRV
|.|..|| |||||...   .  |   ||.|||||| ||  ||  ||||||||||||||  .||..||||| .| .  ... |.||||| |||||||.   
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

NYGPAVDWWTLGILLYEMLFQTTPFFHQNTSRMFTRILMDPVVFPKGADPDVCSLITGLLQKRDRKRYAYE----DIIKHPFF
 .. .|||| ||..||||..   ||...|.. |.  |.  |  .|..  .| ..||.|||||  .||        .| .||||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 94230.m00031.AA AktR 110-361 41 8.99999999999e-110 370.98 In-house 1-268 (268) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-268/268
Sequence Identity: 41% (110 aa)

FKVLSVLGRGNYGKVMLAEKI-DSGELFAIKSVHKKRLALAGKVHTMLSERNTLI-NASNPFIVKLFYAFQNATKFYLVLEYVPGGEMFNYMSTNGAVPL
|.|. .||.|..|||.|..|  |.....|.|...|| .    . | .. ||| ..  ...||||||.|.||. .| ....||.||||.|.. ....    
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

EDARIYAAEIVTALHFLHQN-DIIYRDLKPENILLAQDGHIKLTDFGFAK---DLSQSEVTKTFCGTNEYLAPEVISR-VNYGPAVDWWTLGILLYEMLF
|.||.|.|.|. || .|||. .||||||||||||| .|||.|.|||| .|   . . .|....||||.||.|||.| . . .. .||||..||..|||..
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

QTTPFFHQNTSRMFTRILMDP-VVFPKGADP--DVCSLIT-GLLQKRDRKRYA-----YEDIIKHPFF
  .||.|.|. .|| .|.  . . ||. ...     .||. .||.|. .||        |.| .||.|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 94230.m00031.AA PKA 110-361 43 4.8e-98 332.03 In-house 1-263 (263) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-263/263
Sequence Identity: 43% (115 aa)

FKVLSVLGRGNYGKVMLAEKIDSGELFAIKSVHKKRLALAGKVHTMLSERNTLINASNPFIV-KLFYAFQNATKFYLVLEYVPGGEMFNYMSTNGAVPLE
|. . .||.| .|.|||. . .||. .|.|   | .      |.  ..|.| | | ..|||| |. . ||.... |.|.||||||||| |.  .|  .  
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

DARIYAA-EIVTALHFLHQNDIIYRDLKPENILLAQDGHIKLTDFGFAKDLSQSEVTKTFCGTNEYLAPEVISRV-NYGPAVDWWTLGILLYEMLFQTTP
.|..||| .|| || .||. .||||||||||||. ..||||.||||||| .    .|.| ||| ||||||.|..   .| .||||.|||| ||||.  .|
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPP

FFHQ--NTSRMFTRILMDPVVFPKGADPDV---CSLITGLLQKRDRKRY---AY--EDIIKHPFF
|.    ..  .. .|.   . ||   |.|.    .||  |||.   |||       .|| .|..|
FYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 94230.m00031.AA RSK 113-361 38 1e-96 327.64 In-house 1-278 (278) Show / Hide 
Range on Protein: 113-361
Range on HMM: 1-278/278
Sequence Identity: 38% (108 aa)

LSVLGRGNYGKVMLAEKI---DSGELFAIKSVHKKRLALAGK-VHTMLSERNTLINAS-NPFIVKLFYAFQNATKFYLVLEYVPGGEMFNYMSTNGA---
|.|||.| |||| |  |.   |.| ..| | ..|. .. . | . . . ||| |      ||||.|.||||  .|.||..||..|||.|   .. .    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

VPLEDARIYAAEIVTALHFLHQNDIIYRDLKPENILLAQ---DGHIKLTDFGFAKDLSQS--EVTKTFCGTNEYLAPEVIS----RVNYGPAVDWWTLGI
   ..|..|.|||| |. .||| .||.|||||||||...   .||||||||||.| .. .  . |.|||.| ||.|||..     .. .. |.|||.||.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LLYEMLFQTTPFFH---QNTSRMFTRILMDP--VVFP--KGADPDVCSLITGLLQKRDRKRYA-----YEDIIKHPFF
|.||||.  .|| .   .| .  ..||.     . .|  .   ..  .||...|..   ||.       |.| .||.|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 94230.m00031.AA S_TKc 110-361 34 8.4e-96 325.5 SMART 1-231 (231) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-231/231
Sequence Identity: 34% (92 aa)

FKVLSVLGRGNYGKVMLAEKIDSGELFAIKSVHKKRLALAGKVHTMLSERNTLINASNPFIVKLFYAFQNATKFYLVLEYVPG--GEMFNYMSTNGA---
...| ..|.| .|||... ....|...||| ..           ....|.. | .   |.||||...||. ...|.|.||..|  |..| |.  .|    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---VPLEDARIYAAEIVTALHFLHQNDIIYRDLKPENILLAQDGHIKLTDFGFAKDLSQSEVTKTFCGTNEYLAPEVISRVNYGP-AVDWWTLGILLYEM
    |  .|| |...|. || ..|.. ||.|||||||||| .  |||..|||.|. |      .||||| .|.||||.    ||. ..||| .|..||||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LFQTTPFFHQNTSRMFTRILMDPVVFPKGADPDVCSLITGLLQKRDRKRYAYEDIIK-------HPFF
|   .||   .  .|| .|.          .|.....| ..|||  .||.   .. .       ||.|
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 94230.m00031.AA RSK-Unclassified 110-361 36 1.4e-93 294.32 In-house 1-283 (283) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-283/283
Sequence Identity: 36% (104 aa)

FKVLSVLGRGNYGKVMLAEKIDSGELFAIKSVHKKRLALAGKVHTMLSERNTLINASNPFIVKLFYAFQNATKFYLVLEYVPGGEMFNYMS--TNGAVPL
| .   .|.|  ||| | .| |.  ..|.|  ||...    |.   . |.| .     ||||.|...||   . ||..|| .||..|  .       .  
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

EDARIYAAEIVTALHFLHQNDIIYRDLKPENILLAQDGHIKLTDFGFAKDL----------------------SQSEVTKTFCGTNEYLAPEVISRVNYG
.|.|.||.|.. ||  ||  |.|||||||.||.| |.||..||||.  ..                       . .  |. |||| ||||||.| |   .
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHT

PAVDWWTLGILLYEMLFQTTPFFHQNTSRMFTRILMDPVVFP--KGADPDVCSLITGLLQKRDRKRY-----AYEDIIKHPFF
 |||||||||..|||||  .|.   |.  .|. |.  .| ||  .    .  .||  |||. . ||        .|| .||||
KAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF
Kinase 94230.m00031.AA PKC 110-361 38 7.8e-89 288.06 In-house 1-262 (262) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-262/262
Sequence Identity: 38% (102 aa)

FKVLSVLGRGNYGKVMLAEKIDSGELFAIKSVHKKRLALAGKVHTMLSERNTLINASN-PFIVKLFYAFQNATKFYLVLEYVPGGEMFNYMSTNGAVPLE
|. | |||.|..|||||||. .. |..||| . |        |   . |.  |  |.. || ..|.  ||   . . |.||| ||     .   .  ..|
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

DARIYAAEIVTALHFLHQNDIIYRDLKPENILLAQDGHIKLTDFGFAKD-LSQSEVTKTFCGTNEYLAPEVISRVNYGPAVDWWTLGILLYEMLFQTTPF
 || |||||. ||.|||...||||||| .|.|| ..||||..||| .|. . . . |.||||| .|.|||...   ||..|||| .|.|.|||.    ||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

FHQNTSRMFTRILMDPVVFPKGADPDVCSLITGLLQKRDRKRYAY--------EDIIKHPFF
  ..   .|  |..| ...|.    .  |...|...|   ||           .|| .||||
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase 94230.m00031.AA Pkinase 110-361 30 2.9e-82 284.41 Pfam 1-293 (293) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-293/293
Sequence Identity: 30% (89 aa)

FKVLSVLGRGNYGKVMLAEKIDSGELFAIKSVHKKRLALAGKVHTML-SERNTLINASNPFIVKLFYAFQNATKFYLVLEYVPGG----EMFNYMS--TN
.......|.|..|.| .. ....|...|.| . |..     ...  . ||   . . . |.||.|...|.. .. |.|.||..||    . | |.|   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GAV--PLEDARIYAAEIVTALHFLHQNDIIYRDLKPENILLAQDGHI----KLTDFGFAKD--LSQSEVTKTFCGTNEYLAPEVIS-RVNYGPAVDWWTL
|..  . .... |. .|. .| ..|.. ||.|||||||||. ..|||    |..|||.||   .  .. ..||||| .|.|||||  .  |||.||.| .
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GILLYEMLFQTTPFFHQ------NTSRMFTRILMDPVVFPKGAD---------------------PDVCSLITGLLQKRDRKRYAYEDIIKHPFF
|..|||||.  .|| ..      .   |. ||.. |. |.   .                     .. ...|...|.|   ||.  |.| .||.|
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 94230.m00031.AA p70 110-361 37 3.3e-82 279.42 In-house 1-299 (299) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-299/299
Sequence Identity: 37% (111 aa)

FKVLSVLGRGNYGKVMLAEKID---SGELFAIKSVHKKRLALAGK--VHTM------------------------LSERNTLINASNPFIVKLFYAFQNA
|. | |||.| ||||..  |     .| ..| |   |       |   ||                         . ||| |     |||..|.||||  
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN

TKFYLVLEYVPGGEMFNYMSTNGAVPLEDARIYAAEIVTALHFLHQNDIIYRDLKPENILLAQDGHIKLTDFGFAK-DLSQSEV----------TKTFCG
 | ||.||| .||| |      |  . . |. |..||. || .||| .||||||||||..| | ||..|||||  |  .  ..|          | ||||
GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG

TNEYLAPEVISRVNYGPAVDWWTLGILLYEMLFQTTPFFHQNTSRMFTRILMDP--VVFPKGADPDVCSLITGLLQKRDRKRYA-----YEDIIKHPFF
| || |||...|. .. ||||| ||.|.| ||    ||   |       ||     .  |    ..   ||  || .   .|        .|| .||||
TIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF
Kinase 94230.m00031.AA RSK 110-361 31 3e-80 272.91 In-house 1-271 (271) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-271/271
Sequence Identity: 31% (86 aa)

FKVLSVLGRGNYGKVMLAEKI---DSGELFAIKSVHKKRLALAGKVHTMLSERNTLINASNPFIVKLFYAFQNATKFYLVLEYVPGGEMFNYMSTNGAVP
. .....|.| ..|| .  |.   |.. ..|.| . |. .. . .      ||. | .   ||||||.|.|| ..| |....   ||..|  ..  .  .
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFS

LEDARIYAAEIVTALHFLHQNDIIYRDLKPENILLAQD----GHIKLTDFGFAKDL-SQSEVTKTFCGTNEYLAPEVISRVNYGPAVDWWTLGILLYEML
 .....|.|||  |. .||. .|..|||||||||.. .    ||||..|||||| | .. . ..|||.| .|.||||..|  .. |.||| .|.|.||||
EREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEML

FQTTPFFHQNTSRMFTRILMDPVVF-------PKGADPDVCSLITGLLQKRDRKRYAY-----EDIIKHPFF
  .||| ...  .... |.  ...        .    .   .|....|     .|.       |.| .||.|
TGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase 94230.m00031.AA S_TK_X 362-422 32 3.2e-17 64.46 SMART 1-79 (79) Show / Hide 
Range on Protein: 362-422
Range on HMM: 1-79/79
Sequence Identity: 32% (28 aa)

NGIDWDKVLT--KSYVPSYKPPIK----SKKDVSNFDQEFTAEPAMDSVGSVAPTPIQR-------------------IADFSYVA
 ||||||..   | . | .||.||    |  |.||||.||| |..|        ||...                    ..|.||.
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM-------LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 94230.m00031.AA TyrKc 110-361 16 9.5e-14 -0.37 SMART 1-280 (280) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-280/280
Sequence Identity: 16% (47 aa)

FKVLSVLGRGNYGKVMLAEKIDSGELFAIKSVHKKRLALAGKVHTMLSERNTLINA--SNPFIVKLFYAFQNA-------TKFYLVLEYVPGGEMFNYMS
 . . .||.|..|.|.... .   .  |.|....        .  ...| . . .   ..| ||.|. .              ..|.||.|.|   .|  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

TNGA-VPLEDARIYAAEIVTALHFLHQNDIIYRDLKPENILLAQDGHIKLTDFGFAKDLSQS-------EVTKTFC--GTNE-----YLAPEVISRVNYG
 ..  ....|   ..  |     .||.. .| |||   |.|.. ....| .||| ..|.          .. ..    |..       .|||.|    . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

PAVDWWTLGILLYEMLFQTTPFFHQ-----NTSRMFTRILMDP--VVFPKG--------ADPDVCSLITGLLQKRDRKRYAYEDIIKHPFF
.. | |  |....|..    .          . .   . ...      |.         . ... ....   .    .|   ..|  | .|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 94230.m00031.AA Pkinase_Tyr 110-258 21 1.3e-08 29.81 Pfam 1-161 (270) Show / Hide 
Range on Protein: 110-258
Range on HMM: 1-161/270
Sequence Identity: 21% (35 aa)

FKVLSVLGRGNYGKVMLAEKI----DSGELFAIKSVHKKRLALAG-KVHTMLSERNTLINA-SNPFIVKLFYAFQ-NATK--FYLVLEYVPGGEMFNYMS
 . . .||.|..|.|....      . .   |.|.. |        .   ...| ... .  ..| ||.|  .          |.|.||.|.| . .|  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

T----NGAVPLEDARIYAAEIVTALHFLHQNDIIYRDLKPENILLAQDGHIKLTDFGFAKDL
.    .......|   ....|  .. .|... .| |||   |.|.. ....| .||| |.|.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI
Kinase 94230.m00031.AA Pkinase_C 381-424 36 1.6e-08 33.32 Pfam 1-46 (46) Show / Hide 
Range on Protein: 381-424
Range on HMM: 1-46/46
Sequence Identity: 36% (17 aa)

PIKSKKDVSNFDQEFTAEPAMDSV---GSVAPTPIQRIADFSYVASL
 .||. |.|||| ||| ||.||..       .       .|.||.. 
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFTYVNPD