Gene 85495.m00111 (T.vaginalis)

85495.m00111

Species: T.vaginalis
Alias: TvagK0915, 85495.m00111
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
85495.m00111.AA Protein None 369 None Fasta, JSON
85495.m00111.kin_dom Protein Kinase Domain None 108 None Fasta, JSON

Protein domain

Protein domains of 85495.m00111.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 85495.m00111.AA CAMKL 185-259 26 6.8e-16 47.06 In-house 214-295 (297) Show / Hide 
Range on Protein: 185-259
Range on HMM: 214-295/297
Sequence Identity: 26% (22 aa)

GQKSDMWSLGVLLWFMVTKQLPWSMNNV--------VVMLKTIQTGGPI-NFGILPPEIRDIAASLLVLSPEKRIDTEQIVHNR
|.| |.||.||.| .||. .||.   ..          ..|.... . .  .  .. . ||.  ..|.  ||||.  .||.  .
GPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHP
Kinase 85495.m00111.AA Ciliate-E2 171-255 23 6.4e-13 40.66 In-house 252-359 (365) Show / Hide 
Range on Protein: 171-255
Range on HMM: 252-359/365
Sequence Identity: 23% (28 aa)

GFLAPEYLS--------EGMFPGQKSDMWSLGVLLWFMVTKQLPWSMNNVVVMLKTIQTGGPINFG-------------------ILPPEIRDIAAS---
|..||| |.        ..   . |.|.|||||.| .|.....|.           ..  ..|.|                     ...|  |.      
GYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGK

-LLVLSPEKRID-TEQI
 .|.  |||||.  |||
RMLQKDPEKRITGWEQI
Kinase 85495.m00111.AA MARK 185-256 33 1.7e-12 37.35 In-house 184-257 (262) Show / Hide 
Range on Protein: 185-256
Range on HMM: 184-257/262
Sequence Identity: 33% (25 aa)

GQKSDMWSLGVLLWFMVTKQLPWS--MNNVVVMLKTIQTGGPINFGILPPEIRDIAASLLVLSPEKRIDTEQIV
|.| |.|||||.| |||. ..|.    .. . . | |..| .  .  ...|.|..  .||.. ||.|.. |.|.
GPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIM
Kinase 85495.m00111.AA S_TKc 10-264 17 5.6e-11 -15.98 SMART 1-231 (231) Show / Hide 
Range on Protein: 10-264
Range on HMM: 1-231/231
Sequence Identity: 17% (47 aa)

FIFLKNLNSGFLGPSYLLKKEDTGVNFICKSFLKSSIGDEADVDNFIQIIRMTRKVKESCFLPYHYYYDEEKYIYALRPFFEG--LDLASYITNCS----
. .|. . .|  |  |. .. .||  . .|             ..... |.. .| .      ....... ...|    . .|   || .|| ..     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---TNINVATAQWKVLVRLYRHLHKRKITPIFIKPSNVFMENGTIAFITD-----IYPPPRQFNATLHRTNPLEVG---FLAPEYLSEGMFPGQKSDMWS
    .  .|    . ...   ..|...|    .||.|... .     |.|     ..                 .|   ..||| |    . . |.|.||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------------TTFCGTPWYMAPEVL---GYGKCKCDWWS

LGVLLWFMVTKQLPWSMNNVVVMLKTIQTGGPINFGILPPEIRDIAASLLVLSPEKRIDTEQIVH----NRANTLV
.|..|. |.. . |..  .. .|.| |           .|| .|.   .|.  ||||.   .. .     ..   .
CGCILYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 85495.m00111.AA Pkinase 171-257 21 1.2e-10 38.77 Pfam 176-289 (293) Show / Hide 
Range on Protein: 171-257
Range on HMM: 176-289/293
Sequence Identity: 21% (25 aa)

GFLAPEYLSEGMFPGQKSDMWSLGVLLWFMVTKQLPWSMN------NVVVMLKTIQTGGPINFGILP---------------------PEIRDIAASLLV
...||| . .|   |.|.||||.|..|. |.....|..        .  .|.. |  . .      .                     .| .|.  ..| 
WYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLC

LSPEKRIDTEQIVH
. |.||.  |||..
KDPKKRPTAEQILQ
Kinase 85495.m00111.AA MELK 174-260 29 1.8e-10 31.67 In-house 167-254 (254) Show / Hide 
Range on Protein: 174-260
Range on HMM: 167-254/254
Sequence Identity: 29% (26 aa)

APEYLSEGMFPGQKSDMWSLGVLLWFMVTKQLPWSMNNVVVMLKTIQTGGPINFGILPPEIRDIAASLLVLSPEKRIDTEQIV-HNRA
||| ..   . |   |.||.|.||. ..   ||.   |. .| | |. |       | || ...   .|   |.|||   ... |.  
APELIQGKQYIGSEADVWSMGILLYVLMCGFLPFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV
Kinase 85495.m00111.AA CAMK 185-255 22 1.9e-10 29.15 In-house 312-419 (425) Show / Hide 
Range on Protein: 185-255
Range on HMM: 312-419/425
Sequence Identity: 22% (24 aa)

GQKSDMWSLGVLLWFMVTKQLPWSMN-------------NVVVMLKTIQTGGP--INFGILP----------------------PEIRDIAASLLVLSPE
|.|.||||.||.| .|..  .|.                |   ... |..|    . . . |                      .| .|   ..|.  ||
GPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPE

KRIDTEQI
||.  ||.
KRMTIEQC
Kinase 85495.m00111.AA Ciliate-E2-Unclassified 171-255 23 1.8e-09 29.01 In-house 227-346 (352) Show / Hide 
Range on Protein: 171-255
Range on HMM: 227-346/352
Sequence Identity: 23% (29 aa)

GFL----APEYLSEGMFPG----QKSDMWSLGVLLWFMVTKQLPWSMNNVVV----------------MLKTIQTGGPINFG--------ILPPEIRDIA
...    |||.| .|  ..     |.|.|||||.| .|.. ..| . ||                   ... |. . . ..         ...||  |. 
NYMPQYTAPEVL-QGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFI

A----SLLVLSPEKRIDTEQI
     ..|.  |.|||. |||
NDLLQKMLKKNPNKRITFEQI
Kinase 85495.m00111.AA GIN4 174-261 31 5.3e-09 24.45 In-house 202-293 (293) Show / Hide 
Range on Protein: 174-261
Range on HMM: 202-293/293
Sequence Identity: 31% (29 aa)

APEYLSEGMFPGQKSDMWSLGVLLWFMVTKQLPWSMN--NVVVMLKTIQTGGPINFGI--LPPEIRDIAASLLVLSPEKRIDTEQIVHNRAN
|||  .   . |  ||.|| ||.|. ..| .||.  .  |.  .|  .| |         .  | .|. . .||. ||||| | .|..    
APEIVMGIPYHGFASDVWSCGVILFALLTGHLPFDEEDGNIRKLLLKVQKGKYEMPSDDEISREAQDLIRKILVVDPEKRIKTRDILKHPLI
Kinase 85495.m00111.AA TK 173-259 19 2.3e-08 23.32 In-house 352-486 (486) Show / Hide 
Range on Protein: 173-259
Range on HMM: 352-486/486
Sequence Identity: 19% (26 aa)

LAPEYLSEGMF--------PGQKSDMWSLGVLLWFMVT---KQLPWSMNN--------VVVMLKTIQTGG----------------PINFGILP------
.||| | .. |           |||.||.|||.| ..|   .. .. |.|        .  ... ...||                |   .  .      
MAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRM

-------PEIRDIAASLLVLSPEKRIDTEQIVHNR
       .|. |.  .   . ||.| . .|...  
HPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 85495.m00111.AA InsR 174-202 58 3.2e-07 20.22 In-house 189-216 (278) Show / Hide 
Range on Protein: 174-202
Range on HMM: 189-216/278
Sequence Identity: 58% (17 aa)

APEYLSEGMFPGQKSDMWSLGVLLWFMVT
||| | .| |   .||.||.||.|| |||
APESLKDGVFTT-HSDVWSFGVVLWEMVT
Kinase 85495.m00111.AA Ciliate-E2b 172-207 30 2e-06 15.59 In-house 171-210 (272) Show / Hide 
Range on Protein: 172-207
Range on HMM: 171-210/272
Sequence Identity: 30% (12 aa)

FLAPEYLS----EGMFPGQKSDMWSLGVLLWFMVTKQLPW
..||| ..     |   . |.|.||.|. |...  ...||
YMAPEIIQSLQPGGKGYTYKVDIWSVGICLYEFMCGYVPW
Kinase 85495.m00111.AA TyrKc 10-260 16 0.000126 -147.81 SMART 1-280 (280) Show / Hide 
Range on Protein: 10-260
Range on HMM: 1-280/280
Sequence Identity: 16% (49 aa)

FIFLKNLNSGFLGP--SYLLKKEDTGVNFICKSFLKSSIGDEADVDNFIQIIRMTRKV--KESCFLPYHYYYDEE-------KYIYALRPFFEGLDLASY
  ..| | .|. |      .|     ..   |.  ...      .  |.. .|. .|.  .  . .  . .  ..       . .. .  . .. || .|
ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

ITNCSTNINVATAQWKVLVRLY-------RHLHKRKITPIFIKPSNVFMENGTIAFITD------IYPP------PRQFNATL--HRTNPLEVGFLAPEY
. ..  .      ..| |.          ..||....    .   |.   .. .. |.|      ||             ..   ..  .| .  .||| 
LRKHRPK-----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC

LSEGMFPGQKSDMWSLGVLLW--FMVTKQLPWS-----MNNVVVMLKTIQTGGPINFGI--------LPPEIRDIAASLLVLSPEKRIDTEQIVHNRA
. .|.|   ||| || ||..|  |   .| ..      |.|  |. .  | . .              |.|. .|  .     ||.|   ..| | . 
INYGKF-TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase 85495.m00111.AA Ciliate-E2-Unclassified 10-40 13 0.030432 3.61 In-house 1-35 (352) Show / Hide 
Range on Protein: 10-40
Range on HMM: 1-35/352
Sequence Identity: 13% (5 aa)

FIFLKNLNSGFLGPSYLLKKEDTGVNF-----ICKS
....| ...|  |  |........  .     ..|.
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKI
Kinase 85495.m00111.AA Ciliate-E2b 10-143 18 0.035569 2.6 In-house 1-139 (272) Show / Hide 
Range on Protein: 10-143
Range on HMM: 1-139/272
Sequence Identity: 18% (26 aa)

FIFLKNLNSGFLGPSYLLKK-EDTGVNFICKSFLKSSIGDEADVDNFIQIIRMTRKVKESCFLPYHYYYDEEKYIYALRPFFEGLDLASYITNCS---TN
.|. | | .|  |. || ..  .|   .  |.. |..|  .   .  .| .   .|..      . . .  ....| .  |  |..| ..| .      .
MIYIKKLGFGQFGSVYLVWNTKNTKQYYAMKCISKNQIIQQNMEKHMLQEKNVLEKCNHPFIMKFIRSFKDDQHMYFMMEFCNGMELFDVIREIGRLLLS

INVATAQWKVLVRLYRHLHKRKITPIFIKPSNVFMEN-G
 ...    . ..   . ||...|    |||.|.   . |
TYDSQFYIASICLCLEYLHNQNIIYRDIKPENIMVDHKG