Gene 95068.m00196 (T.vaginalis)

95068.m00196

Species: T.vaginalis
Alias: TvagK0431, 95068.m00196
External Links:
Annotation:

Classification

Group: AGC
Family: PKA

Sequence

Name Sequence Type Origin Length Description Download
95068.m00196.AA Protein None 270 None Fasta, JSON
95068.m00196.kin_dom Protein Kinase Domain None 258 None Fasta, JSON

Protein domain

Protein domains of 95068.m00196.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 95068.m00196.AA AGC 12-269 25 1.5e-87 225.72 In-house 1-395 (395) Show / Hide 
Range on Protein: 12-269
Range on HMM: 1-395/395
Sequence Identity: 25% (101 aa)

FLIEKQIGLGSYGKIVLAKHK------ASGALYAIKMVSRRN-VQKSK--RLETANIE------------KRCLESID----------SQYVVK-LYGYF
| . | || ||.||  |...|      ..| .||.|... .  ... |   .| ...|            .. || ..          ....|| |.  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

EDPLC--FNFVLEYVE---------GG-DMFTLRHEL-------VPQLPHIFKQ-------VVSSLAYLHS-HKIIHRD-IKLENILVDHNNNIKLCDFG
.|.      ||.||..         || ..|.  ..         ..  ... .       .|. | |||| ..||||| .|.|||| |.. .|||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

SAKICE-----------------------------------------------------EETSTFCRSSYIG--SADYTAPEILNKQDICHALDLWD--L
..|.                                                       . |.|||     |  ...| |||||      .| | |   |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFC-----GPCTPEYMAPEIL----YGKACDWWSFGL

GIAIYAAYNGHGPFYSLN----------RLQVFDNIR------NCKYAMV----------ETIPGAAQDLISKLLKLDPKERLGY--NDFS-TGYSTILS
|. .|    |. |||. |          . ..|..|.      |.|  .           . .   |.|||.|||. ||..|||.  |||.  |.. | .
GCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKN

HPYF
||.|
HPWF
S_TKc 95068.m00196.AA S_TKc 12-269 29 2e-72 247.85 SMART 1-231 (231) Show / Hide 
Range on Protein: 12-269
Range on HMM: 1-231/231
Sequence Identity: 29% (80 aa)

FLIEKQIGLGSYGKIVLAKHKASGALYAIKMVSRRNVQKSKRLETANIEKRCLESIDSQYVVKLYGYFEDPLCFNFVLEYVEG--GDMFTLRHELVPQ--
. | ..|| |..||  ...|| .| ..|||...          |..  | ..|.. .  ..||||..|.|  .. .|.||..|  ||.|.. ..  ..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LP----HIFKQVVSSLAYLHSHKIIHRDIKLENILVDHNNNIKLCDFGSAKICEEETSTFCRSSYIGSADYTAPEILNKQDICH-ALDLWDLGIAIY
   .|    ....|... |.|.|||.|||||.| ||||.|.  .||.||||.|..          ....|. .| |||.|      . . | | .|. .|
RFPFPEHARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

AAYNGHGPFYSLNRLQVFDNIRNCKYAMVETIPGAAQDLISKLLKLDPKERLGYNDFSTGYSTILSHPYF
  . |  ||.  .  ..|..|.          .  | |.|.|.|. ||..|..  .  .. . | .||.|
EMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 95068.m00196.AA Ciliate-E2 12-269 22 4.1e-64 218.99 In-house 1-365 (365) Show / Hide 
Range on Protein: 12-269
Range on HMM: 1-365/365
Sequence Identity: 22% (86 aa)

FLIEKQIGLGSYGKIVLAKH-----------------------KASGALYAIKMVSRRNVQKSKRLETAN----------IEKRCLESIDSQYVVKLYGY
. . |.|| |..|.. ..|.                       |. . .||.|... ....  |. .  .          .||. ||.... ...|.| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--DPLCFNFVLEYVEGGDMFT-------LRHELVP--------QLPHIFKQVVS---------------SLAYLHSHK-IIHRDIKLENILVDHNNNI
|.  |  .. .|.||..|||.|         |..  .        .  .|.||...                | |||| . |||||||.||||.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLCDFGSAKICEEE-----------TSTFCR-------------------SSYIGSADYTAPEILNKQD---------ICHALDLWDLGIAIYAAYNGHG
|..||| .|.. ..             .| .                    ...|.. | ||||||...           .. |.| ||. .|    |  
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFYSLNRLQVFDNIRNCKYA------------------MVETIPGAAQDLISK----LLKLDPKERLGYNDFSTGYSTILSHPYF
||        ...| .||.                     . ..  ..|||.|    .|. ||..|..      |.. || ||.|
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT------GWEQILNHPWF
Kinase 95068.m00196.AA Pkinase 12-269 27 2.7e-61 214.74 Pfam 1-293 (293) Show / Hide 
Range on Protein: 12-269
Range on HMM: 1-293/293
Sequence Identity: 27% (83 aa)

FLIEKQIGLGSYGKIVLAKHKASGALYAIKMVSRRNVQKSKRLETAN-IEKRCLESIDSQYVVKLYGYFEDPLCFNFVLEYVEGG----DMF----TLRH
. |...|| ||.|.  ...|| .| ..|.| ...|.  ..|. . ..  | . . .... ..|.||..|||.    .|.||.|||    | |    | ||
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

ELV----PQLPHIFKQVVSSLAYLHSHKIIHRDIKLENILVDHNNNI----KLCDFGSAKICEEETSTFCRSSYIGSADYTAPEILN-KQDICHALDLWD
  .     .. ....|... |.|.||..|||||.|.||||.|.|..|    |.||||.||  . . .    ... |. .| |||...  |.. .. | | 
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGIAIYAAYNGHGPFYSL------NRLQVFDNIRNCKYAMVETIP---------------------GAAQDLISKLLKLDPKERLGYNDFSTGYSTILSH
.|. .|  ..|. ||..       . .|....|. ...   .  .                      ...|.|...|..|||.|..          || |
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-------AEQILQH

PYF
|.|
PWF
Kinase 95068.m00196.AA CAMK 17-269 18 4.3e-60 192.01 In-house 1-425 (425) Show / Hide 
Range on Protein: 17-269
Range on HMM: 1-425/425
Sequence Identity: 18% (81 aa)

QIGLGSYGKIVLAKHKASG------------ALYAIKMVSRRNVQK-------------------------SKRLETANIEKRCLES-------IDSQYV
..| ||.||  |..|| ..              .|||..... ...                          | ..    | ... .       .|   .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKLYGYFED-------------------PLCFNFVL---EYVEGGDMFTLRHELVPQLPH-----------------------IFKQVVSSLAYLHSHKI
.||| ..||                   . .. .|.   ||..||..|    . . . ..                       .|.|..| ..|.|||.|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDIKLENILVDHN-----------------NNIKLCDFGSAKICEEETSTF---------------------CRSSYIGSADYTA-PEILNKQD----
.|||.|.||||.|.|                 ||||..||| |.....  . |                       . . |.  | | ||.||..     
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

----------ICHALDLWDLGIAIYAAYNGHGPFYSLNRLQVFD-------------NIRNCKYA-MVETIPG-----------------------AAQD
          .  . | | .|.  |.   |. |||. .. . ..             .|...||    . ...                        ..|
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LISKLLKLDPKERLGYNDFSTGYSTILSHPYF
||.|.|. ||..|.   .       .|.|| .
LIRKMLQVDPEKRMTIEQ-------CLNHPWM
Kinase 95068.m00196.AA RSK 13-269 28 5.3e-54 185.73 In-house 1-278 (278) Show / Hide 
Range on Protein: 13-269
Range on HMM: 1-278/278
Sequence Identity: 28% (81 aa)

LIEK-QIGLGSYGKIVLAKHKASGALYAIKMVSRRNVQKSKR-LETANIEKRCLESID-SQYVVKLYGYFEDPLCFNFVLEYVEGGDMFT-LRHELV---
| .. |.| |..       |...| .|| | .... . .... ....  | ..|| .  .. .|.|.  |.... .  ..||..||..|| |..|     
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

---PQLPHIFKQVVSSLAYLHSHKIIHRDIKLENILVDH---NNNIKLCDFGSAKI--CEEETSTFCRSSYIGSADYTAPEILN---KQD-ICHALDLWD
        .. ..|. . .||...|||||.|.|||| |.   .  |||.||| .|.  |...  |    .......| |||.|.   .|    .| |.| 
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTM---TFCYTIEYMAPEMLKRANQQGGHDKACDWWS

LGIAIYAAYNGHGPFYS---LNRLQVFDNIRNCK--YAMV--ETIPGAAQDLISKLLKLDPKERLGYNDFSTGYSTILSHPYF
||. .|    |. ||..    || .....|...|    |   ...  .|.|||.|.|. ||. |||..    . . |..||.|
LGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCG--PQDAEEIKQHPWF
Kinase 95068.m00196.AA Ciliate-E2-Unclassified 12-269 24 6.7e-52 178.31 In-house 1-352 (352) Show / Hide 
Range on Protein: 12-269
Range on HMM: 1-352/352
Sequence Identity: 24% (88 aa)

FLIEKQIGLGSYGKIVLAKHKASGALYAIKMVSRRNVQKSKRLETAN--------IEKR--------------CLESIDSQYVVKLYGYFEDPLCFNFVL
. | |||| |..||. ...||  . .||.|. .  ...|.|  .. .        ....               | .... ..||.. .|.|  .. .|.
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYVEGGDMFT-LRH---------ELVPQLPH----------------IFKQVVSSLAYLHSHK-IIHRDIKLENILVDHNN---NIKLCDFGSAK-----
||.||||..  ...         .|. .. .                .|.|... | |||. . |||||||.||||.| |.   .||..|||..|     
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

-------------ICEEETSTFC-RSSYIGSADYTAPEILNKQDIC----HALDLWDLGIAIYAAYNGHGPFYSLNRLQ----------------VFDNI
             . .....|||   .|.    |||||.| .|       .. | | ||. .|.   |  |||. |. |                ...||
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMP-Q-YTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

RNCKYAMVE--------TIPGAAQDLISKLLKLDPKERLGYNDFSTGYSTILSHPYF
 ....   .        ...  |.|.|..||. ..| .....    ... || ||.|
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRI---TFEQILNHPWF
Kinase 95068.m00196.AA ULK 12-269 22 2.7e-47 163.45 In-house 1-324 (324) Show / Hide 
Range on Protein: 12-269
Range on HMM: 1-324/324
Sequence Identity: 22% (73 aa)

FLIEKQIGLGSYG-KIVLAKHKAS---GALYAIKMVSRRNVQKSKRL-------ETANIEKRCLESID---SQY--VVKLYGYFEDPLC--FNFVLEYVE
. . ...| ||.| |   ...| .   . ..|.||... . .|.| .       .  . | . .  ..   ...  .|||| .||.. .  . ...|| .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGDMFTLRHELVP-------------QLPHIFKQVVSSLAYLHSHKIIHRDIKLENILVDHNNN------------IKLCDFGSAKICEE-ETSTFCRSS
||| ... ..  .             .  ..||| .. . .||.|.|||||||..|||. ...             .|..||| ||.... . . . . .
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

YI------GSADYTAPEILN----KQDIC-HALDLWDLGIAIYAAYNGHGP----FYSLN----RL-------QVFDNIRNCKYAMVE---TIPGAAQDL
.       |.  | ||.||.    ... . .  |.| ||. .|    |  |    |....    .|       |.. . .. .. ...    |    .||
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDL

ISKLLKLDPKERLGYNDFSTGYSTILSHPYF
|...|. |.|.|    .       |..|| |
IRRMLQYDEKDRISWEE-------IFNHPWF
Kinase 95068.m00196.AA RSK 12-269 28 1.8e-46 160.71 In-house 1-271 (271) Show / Hide 
Range on Protein: 12-269
Range on HMM: 1-271/271
Sequence Identity: 28% (81 aa)

FLIEKQIGLGSYGKIVLAKHK---ASGALYAIKMVSRRNVQKSKRLETANIEKRCLESIDSQYVVKLYGYFEDPLCFNFVLEYVEGGDMFTLRHELVPQL
. . . || ||..|. . | .   ... .||.| .    .  . |  . ....  |. ......|||.  |.|      ...  .|||.|. |   ....
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDRVCWEEERI-ILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFD-RLLKQKMF

P-----HIFKQVVSSLAYLHSHKIIHRDIKLENILVDHN----NNIKLCDFGSAK--ICEEE-TSTFCRSSYIGSADYTAPEILNKQDICHALDLWDLGI
.      .   . ....||||..|.||| | ||||.|        ||.|||| ||  . |.. . |||     ..| | |||.|..|   .| | | .|.
SEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFC-----YTANYMAPEVLKRQGHDQACDWWSFGV

AIYAAYNGHGPFYSLNRLQVFDNIRNCKYAM-------VETIPGAAQDLISKLLKLDPKERLGY-NDFSTGYSTILSHPYF
  |    |. ||.. .|   ...| . | .|        ..|   |.||....|. ||  |||   .   |   |..||.|
LMYEMLTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPN---GVEQIKQHPWF
Kinase 95068.m00196.AA PDK1 114-269 32 3.5e-42 126.67 In-house 118-307 (307) Show / Hide 
Range on Protein: 114-269
Range on HMM: 118-307/307
Sequence Identity: 32% (62 aa)

QVVSSLAYLHSHKIIHRDIKLENILVDHNNNIKLCDFGSA---KICEE---------------ETS---------TFCRSSYIGSADYTAPEILNKQDIC
. .. | .|||..|||||.| ||||.| .. |.. |||.|   || .|               ..          .  ..|  | | |  || |.  ...
EIIDALEHLHSNGIIHRDLKPENILLDKDMHIMITDFGTAGFDKILPEYQSQQQNQFQQQFQQHNKGMDKPEEDKQTRCKSFVGTAEYVSPELLTDKECT

HALDLWDLGIAIYAAYNGHGPFYSL-----NRLQVFDNIRNCKYAMVET--IPGAAQDLISKLLKLDPKERLGYNDFSTGYSTILSHPYF
 . |.| ||  ||    |  ||        | ...|  | .| |.  .   .|  | ||..|||..||..||.  |   ||..|  ||.|
PSCDIWALGCIIYQMVAGQPPFRGMNDATNNEYHTFQKIMKCQYDFPDNFRFPPCAKDLVKKLLVRDPNDRLTSCDECGGYQQIKAHPFF
Kinase 95068.m00196.AA MARK 110-269 34 1.2e-41 134.03 In-house 108-262 (262) Show / Hide 
Range on Protein: 110-269
Range on HMM: 108-262/262
Sequence Identity: 34% (57 aa)

HIFKQVVSSLAYLHSHKIIHRDIKLENILVDHNN--NIKLCDFGSAKICEEET--STFCRSSYIGSADYTAPEILNKQDIC-HALDLWDLGIAIYAAYNG
.||.|.|| . |.||. |.|||||.||||.|.|.  |||..||| . ......  .|||     |.  | ||||..|.. .  . | | ||.  |.   |
RIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFC-----GTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCG

HGPFYSLN--RLQVFDNIRNCKYAMVETIPGAAQDLISKLLKLDPKERLGYNDFSTGYSTILSHPYF
. ||   .    . . .|...||     ..  ...||..||...|.||  . .       |..|| .
YFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEE-------IMKHPWM
Kinase 95068.m00196.AA CAMKL 110-269 30 8.1e-38 118.17 In-house 131-297 (297) Show / Hide 
Range on Protein: 110-269
Range on HMM: 131-297/297
Sequence Identity: 30% (56 aa)

HIFKQVVSSLAYLHSHKIIHRDIKLENILVDHNN--NIKLCDFGSAKI---C----EEETSTFCRSSYIGSADYTAPEILNK--Q-DICHALDLWDLGIA
..|.|.|| ..|.|||.|.|||||.||||.|.|.  |||..||| . .   |    ..  .|||     ||  | ||||...  .  .  . | | .|. 
RYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFC-----GSPPYMAPEIFQGNNKPYDGPKVDIWSCGVI

IYAAYNGHGPFY----------SLNRLQVFDNIRNCKYAMVETIPGAAQDLISKLLKLDPKERLGYNDFSTGYSTILSHPYF
 ||   |. ||              .|   ...  ...     ..  ..|||.|.|. .|..|    .       |..|| .
LYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQ-------IMNHPWM
Kinase 95068.m00196.AA PDK1 12-97 33 3.5e-18 51.8 In-house 1-95 (307) Show / Hide 
Range on Protein: 12-97
Range on HMM: 1-95/307
Sequence Identity: 33% (32 aa)

FLIEKQIGLGSYGKIVLAKHKAS----GALYAIKMVSRRNVQKSKRLETANIEKRCLESIDS-----QYVVKLYGYFEDPLCFNFVLEYVEGGDM
| ..|.|| |||.. .||. |..    .. ||||  . |   . |     ..||  . ...        .||||. | |  |  |||||...||.
FIFGKNIGEGSYSTVYLAREKETKNDENKMYAIKICEKRYIIREKKVKYVHREKEIMCHLNNECNGHPGIVKLYFTFQDEQCLYFVLEYCPNGDL
Kinase 95068.m00196.AA CAMKL 12-98 23 7.1e-18 53.48 In-house 1-111 (297) Show / Hide 
Range on Protein: 12-98
Range on HMM: 1-111/297
Sequence Identity: 23% (26 aa)

FLIEKQIGLGSYGKIVLAKH-KASGALYAIKMVSRRNVQK-------------SKRLETANIEKRCLESID---SQYVVKLYGYFEDPLC------FNFV
. |.|..| ||.||  ||.| .  |  .|||.. ..  ..             ....     | .......    . ..|||  .|.| .      .. |
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

LEYVEGGD--MF
.||..||.  .|
MEYCSGGEMDLF
Kinase 95068.m00196.AA MARK 12-98 26 1.8e-17 53.8 In-house 1-90 (262) Show / Hide 
Range on Protein: 12-98
Range on HMM: 1-90/262
Sequence Identity: 26% (24 aa)

FLIEKQIGLGSYGKIVLAKHKASGALYAIKMVSRRNVQKSKRLETANIEKRCLESIDSQYVVKLYGYFE--DPLC-FNFVLEYVEGGDMF
. . |.|| |||.|  || || .|  .|||.. . . .. . ..    | . . ..|  ...||. ..|  .. . .....||..||...
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELY
Kinase 95068.m00196.AA TyrKc 12-263 18 4.7e-11 -43.98 SMART 1-280 (280) Show / Hide 
Range on Protein: 12-263
Range on HMM: 1-280/280
Sequence Identity: 18% (54 aa)

FLIEKQIGLGSYGKIVLAKHKASGALYAIKMVSRRNVQKSKRLETANIEK--RCLESI--DSQYVVKLYGYFE---------DPLCFNFVLEYVEGGDMF
   .|..| | .|...... |      |.||.             . . .  | . ..  . . .|.|||.           .||.   |.||...||  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLM--IVMEYMPHGDLK

TLRHELVP-----QLPHIFKQVVSSLAYLHSHKIIHRDIKLENILVDHNNNIKLCDFGSAKICEEE-TSTFCRSSYIG-----SAD------YTAPEILN
   ..  |     .| ..  |. .  .||||...||||.   |.||..|. .| .||| ..  ... ..   ...|.      ...       .||| . 
DYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG-ESKDYYRKKEHKGGKTMLPIRWMAPECI-

KQDIC-HALDLWDLGIAIYAAYNGHGPFYS------LNRLQVFDNIRNCKYAMVETI---------PGAAQDLISKLLKLDPKERLGYNDFSTGYSTI
.  .. .. | |  |. ..  .   .. |.      ..  .|. .... .. .             | .  .....  . ||..|     ||. .. .
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRP---TFSEIHECF
Kinase 95068.m00196.AA Pkinase_Tyr 119-151 51 3.4e-08 28.36 Pfam 124-156 (270) Show / Hide 
Range on Protein: 119-151
Range on HMM: 124-156/270
Sequence Identity: 51% (17 aa)

LAYLHSHKIIHRDIKLENILVDHNNNIKLCDFG
..||.|...||||.   |.||..|| .| ||||
MEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase 95068.m00196.AA Pkinase_Tyr 12-97 20 0.943062 3.17 Pfam 1-94 (270) Show / Hide 
Range on Protein: 12-97
Range on HMM: 1-94/270
Sequence Identity: 20% (20 aa)

FLIEKQIGLGSYGKIVLAKHK----ASGALYAIKMVSRRNVQKSK--RLETANIEKRCLESI-DSQYVVKLYGYFE---DP--LCFNFVLEYVEGGDM
  . |..| |..|...... |      .   |.||. . .  ..   | .  . | . . .. . . .|.|||      .|  ..   |.||...||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIY--IVMEYMPHGDL