Gene 92498.m00039 (T.vaginalis)

92498.m00039

Species: T.vaginalis
Alias: TvagK0417, 92498.m00039
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
92498.m00039.AA Protein None 448 None Fasta, JSON
92498.m00039.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of 92498.m00039.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH 92498.m00039.AA PH 8-102 17 1.1e-09 37.54 Pfam 1-92 (92) Show / Hide 
Range on Protein: 8-102
Range on HMM: 1-92/92
Sequence Identity: 17% (17 aa)

PAMSSLLKKKTGFLGMWKTVLCTYIEGVLTIYNGTSERSDKKEIHIDSSVVISYTPNGTSRKFTIQIPNEEPILLTSDDPELTIAWIQALRAETY
. ..  |.||. ... || . ..  ...| .|   .  . |. | ...  |  ...|.    | | . ... ...  ...|    |.||...  .
VIKEGWLHKKG-KRKSWKKRWFVLFNNCLYYYKDDK-YRPKGSIPLSDCQVTKVPDNKRPHCFQIRT-DRRTYYFQAESEEEMNDWMQAIQSACR
PH 92498.m00039.AA PH 8-104 16 2.1e-07 31.87 SMART 1-82 (82) Show / Hide 
Range on Protein: 8-104
Range on HMM: 1-82/82
Sequence Identity: 16% (16 aa)

PAMSSLLKKKTGFLGMWKTVLCTYIEGVLTIYNGTSERSDKKEIHIDSSVVISYTPNGTSRKFTIQIPNEEPILLTSDDPELTIAWIQALRAETYTE
. ..  |.||.  .  || . ..  ...|..|      . |..|....  |   .       |.|   ..  ...  ...|    |.||... ..  
VIKEGWLYKKS--K-RWKKRWFVLFNDCLYYYKDK---KPKGSIPLSDCTVRE-P------CFEIHH-DR-TYYFQCESEEEMQEWMQAIQKAIHNN
Kinase 92498.m00039.AA AGC 113-363 28 3.4e-137 357.02 In-house 1-395 (395) Show / Hide 
Range on Protein: 113-363
Range on HMM: 1-395/395
Sequence Identity: 28% (112 aa)

FNIIATIGRGFFGKVLLVSLP------STNELFAVKIVKKKY---LADNGKTQTILAE------------RNILFKAN----------NDFIVK-MKFAF
|... .||.| |||| ||         .|....|.|..|||.   . .  . . ...|            |||| |.|          ..|||| ....|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QNPTK--FYLGMEYVP---------GG-DLFHIL--D-QYTTLKLEAARLYIAE-------IAIALDYLHS-IGVVYRD-LKPENVLIDKEGHVKLCDFG
|....   |. |||.|         || .||..|  . .. ..  |.|| |.||       |. ||.||||  |...|| |||||.|.|..||.||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSKELNFN---------------------------------------------------AETTTFCG--TTEYIAPEIIQQKPYSYPVDWWA--LGILTY
|.||.. .                                                   . |.||||  | ||.||||.    |....|||.  ||.| |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EILFGDTPFVNPN----------QRITMTSII------SSPPRIP-----------KCPDFVSDFILRLLVKDPAKRAT----------LNDLKGHPFW
| |.| .|| . |          .  .. .|.      . ....|           .  .   |.| .||.|||.|| .           ...| ||. 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 92498.m00039.AA Akt 113-363 39 5.4e-105 336.59 In-house 1-264 (264) Show / Hide 
Range on Protein: 113-363
Range on HMM: 1-264/264
Sequence Identity: 39% (105 aa)

FNIIATIGRGFFGKVLLVSLPSTNELF-AVKIVKKKYLADNGKTQTILAERNILFKANNDFIVKMKFAFQNPTKFYLGMEYVPGGDLFHILDQYTTLKLE
|...  .|.| ||||.||   .|.... | |. ||.|. .... . ...||||| . |. |||.....||...| |. |.|..||.||  | .  . . .
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

AARLYIAEIAIALDYLHSIGVVYRD-LKPENVLIDKEGHVKLCDFGLSK-E-LNFNAETTTFCGTTEYIAPEIIQQKPYSYPVDWWA-LGILTYEILFGD
 || |.|||  |...||| ...||| |||||.|.||.||..|.||||.| . .  . .|.||||| ||.||||.... .. .||||. ||...|| ..| 
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

TPFVNPNQRITMTSIISSPPRIPKCPDFVS----DFILRLLVKDPAKRA-----TLNDLKGHPFW
 || | ..   .  | ..| ..|.  |..|    |.| .|| ||| ||      .....| ||. 
PPFYNQDHHQMFKKIKNQPVKFPDK-DWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 92498.m00039.AA AktR 113-363 38 2.3e-97 329.77 In-house 1-268 (268) Show / Hide 
Range on Protein: 113-363
Range on HMM: 1-268/268
Sequence Identity: 38% (104 aa)

FNIIATIGRGFFGKVLLVSLP-STNELFAVKIVKKKYLADNGKTQTILAERNILF-KANNDFIVKMKFAFQNPTKFYLGMEYVPGGDLFHILDQYTTLKL
| ... .|.| |||| ||     .....| |..||| . .. . . .. ||||.  ..|. ||||....||. .| .. |||.|||.||..| .  ... 
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

EAARLYIAEIAIALDYLHSI-GVVYRDLKPENVLIDKEGHVKLCDFGLSK--ELN-FNAETTTFCGTTEYIAPEIIQQ-KPYSYPVDWWALGILTYEILF
| || |.|.| .||.|||.   ..|||||||| |.|..||||. ||||||    .  . ....|||| ||.|||.|.. |.. ..|||||.||. ||...
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GDTPFVNPNQRITMTSIISSP---PRIPKCP-DFVSDFIL-RLLVKDPAKRAT-----LNDLKGHPFW
| .|| . ||..   .|....   . .|... ..  |.|  .|| |.| || .       ..| ||. 
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 92498.m00039.AA SGK 113-363 37 4.4e-97 300.36 In-house 1-283 (283) Show / Hide 
Range on Protein: 113-363
Range on HMM: 1-283/283
Sequence Identity: 37% (106 aa)

FNIIATIGRGFFGKVLLVSLPST------------------NELFAVKIVKKKYLA-------DNGKTQTILAER-NILFKANNDFIVKMKFAFQNPTKF
| .. .|| | ||||..|   ..                    ..|.|. .|.           . .   |.||| .|| . .  |||. ..|||...| 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLGMEYVPGGDLFHILDQYTTLKLEAARLYIAEIAIALDYLHSIGVVYRDLKPENVLIDKEGHVKLCDFGLSK-ELNFNAETTTFCGTTEYIAPEIIQQK
|. |.|| ||..|  |     ..   || | |||. ||.||||. ..||||||||.| | .||..|.||||.| .   | .|.||||| || |||... .
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

PYSYPVDWWALGILTYEILFGDTPFVNPNQRITMTSIISSPPRIPKCPDFV-SDFILRLLVKDPAKRATLN----DLKGHPFW
|..  |||| ||.. || ..|  || . |  .    ||..| .||.      .| |  || ||| ||   .    . | ||| 
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 92498.m00039.AA S_TKc 113-363 34 1.7e-94 321.15 SMART 1-231 (231) Show / Hide 
Range on Protein: 113-363
Range on HMM: 1-231/231
Sequence Identity: 34% (93 aa)

FNIIATIGRGFFGKVLLVSLPSTNELFAVKIVKKKYLADNGKTQTILAERNILFKANNDFIVKMKFAFQNPTKFYLGMEYVPG--GDLFHILDQYTT---
. |. .||.| |||| ..   .|....|.||.|          ..|. |..|| | . ..|||.. .||. ...|. |||..|  ||||...... .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LKLEAARLYIAEIAIALDYLHSIGVVYRDLKPENVLIDKEGHVKLCDFGLSKELNFNAETTTFCGTTEYIAPEIIQQKPYSY-PVDWWALGILTYEI
   .    || |...|. ||.|.|| |...|||||||.|.|.  |.|.|||||...|      |||||| .|.|||..   .|.. ..|||..|.. || 
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LFGDTPFVNPNQRITMTSIISSPPRIPKCPDFVSDFILRLLVKDPAKRATLNDLKG-------HPFW
| | .||   ..  ..  |          |.. . || ..|.|||.|| |  ..         ||. 
LCGYPPFP--QMQMMFKKIG--------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 92498.m00039.AA RSK 116-363 36 8.6e-89 301.3 In-house 1-278 (278) Show / Hide 
Range on Protein: 116-363
Range on HMM: 1-278/278
Sequence Identity: 36% (101 aa)

IATIGRGFFGKVLLVSLP---STNELFAVKIVKKKYLADNGK-TQTILAERNILFKAN-NDFIVKMKFAFQNPTKFYLGMEYVPGGDLFHILDQYTT---
.   |.| .||| |.       |. ..|.|..||. .. . | | . ..|||||   .   |||. . ||| ..|.|| |||..||.||  | .  .   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LKLEAARLYIAEIAIALDYLHSIGVVYRDLKPENVLIDK---EGHVKLCDFGLSKE--LNFNAETTTFCGTTEYIAPEIIQ---QKP-YSYPVDWWALGI
.  . |. |.|||. |...||. |...|||||||.| |    |||.||.|||..|.  ...|  | |||.| ||.|||..    |.  ..  .||| ||.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LTYEILFGDTPFVN---PNQRITMTSIISSP--PRIPKCPDFVS----DFILRLLVKDPAKRAT-----LNDLKGHPFW
| || |.| .|| .    |.  .|. | .    ...|  ....|    |.| ..| .||.|| .     ....| ||..
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPN-WQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 92498.m00039.AA Pkinase 113-363 32 1.8e-85 295.02 Pfam 1-293 (293) Show / Hide 
Range on Protein: 113-363
Range on HMM: 1-293/293
Sequence Identity: 32% (96 aa)

FNIIATIGRGFFGKVLLVSLPSTNELFAVKIVKKKYLADNGKTQTILA--ERNILFKANNDFIVKMKFAFQNPTKFYLGMEYVPGG----DLFHILD--Q
. |. .||.| ||.| .    .|....||||.||.  .. .| || .   |  |. . | ..||... .|..... |. |||..||    |||...   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

YTTL--KLEAARLYIAEIAIALDYLHSIGVVYRDLKPENVLIDKEGHV----KLCDFGLSKE--LNFNAETTTFCGTTEYIAPEIIQ-QKPYSYPVDWWA
....    . .. |. .|. .|.|.|| |...|||||||.|||..||.    |.|||||.|   .  |  .|||||| .|.|||.|. ...|...||.|.
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGILTYEILFGDTPFVNP------NQRITMTSIIS---SPPRIPKCP-------------------DFVSDFILRLLVKDPAKRATLNDLKGHPFW
.|.. || |.| .|| .       .|.  .  | .   . ..  .|.                   .   ||| ..| |||.|| |  ... ||..
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 92498.m00039.AA PKC 113-363 38 2.3e-81 263.46 In-house 1-262 (262) Show / Hide 
Range on Protein: 113-363
Range on HMM: 1-262/262
Sequence Identity: 38% (100 aa)

FNIIATIGRGFFGKVLLVSLPSTNELFAVKIVKKKYLADNGKTQTILAERNILFKANND-FIVKMKFAFQNPTKFYLGMEYVPGGDLFHILDQYTTLKLE
|| .  .|.| ||||.|. .  |.|..|.|..||    ..      ..|. .|  |..  | ...   || . . .  |||| |||| .   |.  .|.|
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

AARLYIAEIAIALDYLHSIGVVYRDLKPENVLIDKEGHVKLCDFGLSKE-LNFNAETTTFCGTTEYIAPEIIQQKPYSYPVDWWALGILTYEILFGDTPF
 || | |||..|| .||. |..||||| .|||.|.|||.|. |||..|| ..  . |.||||| .||||||.| ..|.  |||||.|.| || . |  ||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

VNPNQRITMTSIISSPPRIPKCPDFVSDFILR-LLVKDPAKRATL--------NDLKGHPFW
   .      ||    |..|.     .  |.  .. |.|.||           .| . ||| 
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase 92498.m00039.AA PKA 113-363 40 4.2e-79 269.1 In-house 1-263 (263) Show / Hide 
Range on Protein: 113-363
Range on HMM: 1-263/263
Sequence Identity: 40% (107 aa)

FNIIATIGRGFFGKVLLVSLPSTNELFAVKIVKKKYLADNGKTQTILAERNILFKANNDFIV-KMKFAFQNPTKFYLGMEYVPGGDLFHILDQYTTLKLE
|.||.|.|.| ||.| |.   .. . .| |. || .  .   .. .. |.|||   .. ||| ||.. ||.... |. |||||||..|. |     .   
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

AARLYIA-EIAIALDYLHSIGVVYRDLKPENVLIDKEGHVKLCDFGLSKELNFNAETTTFCGTTEYIAPEIIQQK-PYSYPVDWWALGILTYEILFGDTP
 |..|.| .|  ||.||||   .|||||||| ||||.||.|. ||| .|..    .| | ||| ||.|||||| | ..  .||||||||| || |.| .|
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPP

FVNP--NQRITMTSIISSPPRIPKCPDFVS----DFILRLLVKDPAKRA-----TLNDLKGHPFW
| .   ..  .   |..   . |   |       |.| .||..|. ||        || | |.. 
FYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 92498.m00039.AA Ciliate-E2-Unclassified 113-363 26 1.8e-73 250.4 In-house 1-352 (352) Show / Hide 
Range on Protein: 113-363
Range on HMM: 1-352/352
Sequence Identity: 26% (92 aa)

FNIIATIGRGFFGKVLLVSLPSTNELFAVKIVKKKYLADNGKTQT---------ILAERN-------------ILFKANNDFIVKMKFAFQNPTKFYLGM
..|| .||.| |||| ..   ......| |. ||.   .  . ..         .. ...             ||   .. ||||| ..||.  ..|. |
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYVPGGDLFHILDQYTT-----------------LKLEAAR-----LYIAEIAIALDYLHSIG-VVYRDLKPENVLIDKEG---HVKLCDFGLSKELNFN
||..||||. .. .. .                 .  ..|.      |.|.|  .|.|||. . ...||.||||.|.|..|   ..|..|||.||... |
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

----------------AETTTFCGTTEYI----APEIIQQKPYS----YPVDWWALGILTYEILFGDTPFVNPNQRI----------------TMTSIIS
                 ...||||| .|.    |||..|.. |.    | .|.|.||.. ||.|||  ||  .|. .                    |. 
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

SPPRIPK-------------CPDFVSDFILRLLVKDPAKRATLNDLKGHPFW
 .. .||             . ||..|.. ..|.|.| || |..... ||. 
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 92498.m00039.AA MAST 113-259 43 3.6e-64 194.69 In-house 1-150 (337) Show / Hide 
Range on Protein: 113-259
Range on HMM: 1-150/337
Sequence Identity: 43% (65 aa)

FNIIATIGRGFFGKVLLVSLPSTNELFAVKIVKKKYLADNGKTQTILAERNILFKANNDFIVKMKFAFQN--PTKFYLGMEYVPGGDLFHILDQYT-TLK
|..|  |..| .|.| ||   .||..|| |. .. ...|    ... .|||||  . |.|.|||  .||    .. .. |||. ||| ...|  |. .. 
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

LEAARLYIAEIAIALDYLHSIGVVYRDLKPENVLIDKEGHVKLCDFGLSK
 . |..||||. ..|.|||| | | |||||.|.|||. ||.|| ||||||
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSK
Kinase 92498.m00039.AA MAST 113-259 45 8.4e-63 201.15 In-house 1-147 (334) Show / Hide 
Range on Protein: 113-259
Range on HMM: 1-147/334
Sequence Identity: 45% (67 aa)

FNIIATIGRGFFGKVLLVSLPSTNELFAVKIVKKKYLADNGKTQTILAERNILFKANNDFIVKMKFAFQNPTKFYLGMEYVPGGDLFHILDQYTTLKLEA
|..|  |..| .||| ||   .||..||.|..|| ....   ...  .|||||  . |.|.|||  .||  .. .. |||. |||....|  |...  . 
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

ARLYIAEIAIALDYLHSIGVVYRDLKPENVLIDKEGHVKLCDFGLSK
|..||||....|.|||| | | |||||.|.|||..||.|| ||||||
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSK
Kinase 92498.m00039.AA MAST 271-363 33 9e-22 66.67 In-house 225-334 (334) Show / Hide 
Range on Protein: 271-363
Range on HMM: 225-334/334
Sequence Identity: 33% (37 aa)

CGTTEYIAPEIIQQKP-YSYPVDWWALGILTYEILFGDTPFVNPNQRITMTSIISSP------PRI------PKCPDFVSDFILRLLVKDPAKRATLN--
||| .|||||.| ... .. |||||..||  ||.| | .||.  .. ..  .|..        |         . .  . | | .||  || || . |  
CGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGANNG

--DLKGHPFW
  . | ||| 
ADEVKQHPFF
Kinase 92498.m00039.AA MAST 271-363 36 1.6e-21 61.96 In-house 229-337 (337) Show / Hide 
Range on Protein: 271-363
Range on HMM: 229-337/337
Sequence Identity: 36% (40 aa)

CGTTEYIAPEIIQQKP-YSYPVDWWALGILTYEILFGDTPFVNPNQR-ITMTSIISSPPRIPKCPDF--------VS----DFILRLLVKDPAKRATLN-
||| .|||||.|  .. |. |||||..||  ||.| | .||.  ..  ..  .||.   .|  .|.         .|    | | .|| ..| ||   | 
CGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREI-EWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGANG

--DLKGHPFW
  . | ||| 
ADEIKQHPFF
Kinase 92498.m00039.AA TyrKc 113-363 21 1.6e-16 44.47 SMART 1-280 (280) Show / Hide 
Range on Protein: 113-363
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

FNIIATIGRGFFGKVLLVSLPSTNELFAVKIVKKKYLADNGKTQTILAERNILFKA--NNDFIVKMKFAFQNP-------TKFYLGMEYVPGGDLFHILD
   . ..|.|.||.| .  .    .  ||| .|.         . .. | .|. |   ... ||..  .   .          .. |||.|.||| . | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

QYTT-LKLEAARLYIAEIAIALDYLHSIGVVYRDLKPENVLIDKEGHVKLCDFGLSKELNFN------AETTTF----CGTT----EYIAPEIIQQKPYS
 .   |...    .   ||   .|||| ... |||   |.|......|| .|||||...          .. .     .| |       ||| |. . ..
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

YPVDWWALGILTYEIL-FGDTPFVN-----PNQRITMTSIISS--PPRIPK--------CPDFVSDFILRLLVKDPAKRATLNDLKGHPFW
   | |. |.. .||. .|..|  .      . .  .  . .   .|. |         ||| . . ...    ||..| | ...  | ..
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 92498.m00039.AA Pkinase_Tyr 113-310 25 8.7e-11 37.15 Pfam 1-216 (270) Show / Hide 
Range on Protein: 113-310
Range on HMM: 1-216/270
Sequence Identity: 25% (57 aa)

FNIIATIGRGFFGKVLLVSLP----STNELFAVKIVKKKYLAD-NGKTQTILAERNILFKA-NNDFIVKMKFAFQ-----NPTKFYLGMEYVPGGDLFHI
  .. ..|.| ||.| .  .     .|.   |||..| ..  . | . .  ..| .|. .  ... ||..  .       |  . |. |||.|.||| . 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQN-CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN--QIYIVMEYMPHGDLLDY

LDQY----TTLKLEAARLYIAEIAIALDYLHSIGVVYRDLKPENVLIDKEGHVKLCDFGLSKELNFNAETT-TFCGTTE----YIAPEIIQQKPYSYPVD
| .       |...    . ..|| ...||.|.. . |||   |.|......|| |||||.. . .| ..  .  | .       ||| |. . ..   |
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSD

WWALGILTYEILF-GDTP-F
 |. |.| .||.  |..| .
VWSFGVLMWEIFTYGEQPTY
Kinase 92498.m00039.AA S_TK_X 364-425 22 3.2e-05 21.42 SMART 1-79 (79) Show / Hide 
Range on Protein: 364-425
Range on HMM: 1-79/79
Sequence Identity: 22% (18 aa)

GELDFELVKQ--KKYTPFFIPP-E----GPNPYCNFDQEFTAEPATDSPATPLSLESPTSE----------VTGFSFTS
 ..|.. . .  |...| |.|.      .|   .|||.||| |.....|. | ...|   .            ||..  
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 92498.m00039.AA Pkinase_C 390-427 30 0.000196 18.94 Pfam 9-46 (46) Show / Hide 
Range on Protein: 390-427
Range on HMM: 9-46/46
Sequence Identity: 30% (12 aa)

CNFDQEFTAEPATDS-PATPLSLESPTSEVTGFSFTSSE
.||| ||| ||..|. | .. . ..  ..  ||......
SNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFTYVNPD