Gene 84943.m00183 (T.vaginalis)

84943.m00183

Species: T.vaginalis
Alias: 84943.m00183, TvagK0383
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
84943.m00183.AA Protein None 434 None Fasta, JSON
84943.m00183.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 84943.m00183.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH 84943.m00183.AA PH 10-93 26 1.6e-09 36.95 Pfam 5-86 (92) Show / Hide 
Range on Protein: 10-93
Range on HMM: 5-86/92
Sequence Identity: 26% (23 aa)

GYLKIKNIQDGLWYKRYCVLTSHTFTIFKDESLNDMEKVIKIDSNTKIDEVPSN-RSPRFSIQNPDG-ILYFSCDCQESLIKWITA
|.|. |  . . | ||..||.. .  ..||..  .  ..| ...  ....||.| |   | | . |.  .||... .|..  |..|
GWLHKKG-KRKSWKKRWFVLFNNCLYYYKDDK-YRPKGSIPLSDC-QVTKVPDNKRPHCFQIRT-DRRTYYFQAESEEEMNDWMQA
PH 84943.m00183.AA PH 6-101 22 6.2e-09 36.92 SMART 1-82 (82) Show / Hide 
Range on Protein: 6-101
Range on HMM: 1-82/82
Sequence Identity: 22% (22 aa)

DGLVGYLKIKNIQDGLWYKRYCVLTSHTFTIFKDESLNDMEKVIKIDSNTKIDEVPSNRSPRFSIQNPDGILYFSCDCQESLIKWITAPNASKVTV
  . |.|..|      | ||..||........||.   .  ..| ...  ...| |      | | . |. .||.|. .|.. .|..| ..     
VIKEGWLYKKS--K-RWKKRWFVLFNDCLYYYKDK---KPKGSIPLSDC-TVRE-P-----CFEIHH-DRTYYFQCESEEEMQEWMQAIQKAIHNN
Kinase 84943.m00183.AA AGC 109-360 28 4.3e-148 385.86 In-house 1-395 (395) Show / Hide 
Range on Protein: 109-360
Range on HMM: 1-395/395
Sequence Identity: 28% (114 aa)

FNIISVIGKGFYGKVMLVQHK------TSGELYALKTIQKRR-LIETH--KAHTVIAE------------RNSLMKAS----------HPFIVR-LCFAF
|... ||||| .|||.||..|      ..|..||.| ..|..  ...   . . ...|            || |.|..          |||||. | ..|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTPQK--FYLGLEYAS---------GG-ELFYHL--D-KAGALPPSEVRLISAE-------IALALSYLHS-LGIVYRD-LKPENVMFDSEGHVKLTDFG
|....   |. .||..         || |||.||  . | | .. ...| . ||       |.||| |||| .||..|| |||||...|..||.||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSKDIV---------------------------------------------------ETNSTNTLCG--TTEYLSPEVVLHNQYDYGVDWWA--LGCLMY
|.| ..                                                   ... |.|.||  | ||..||..    |.. .|||.  ||||||
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMLTERTPFENPN----------RSKMLQDIV------HAQPEFP----------EFLPPDVIEVLSALLSKDPKNRPG----------IDQLKEFAYF
|||| ..|| . |          . .| | |       . ...||          ... |.    .. || |||..|.|          ....|.  .|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 84943.m00183.AA SGK 109-360 39 4.1e-115 357.04 In-house 1-283 (283) Show / Hide 
Range on Protein: 109-360
Range on HMM: 1-283/283
Sequence Identity: 39% (113 aa)

FNIISVIGKGFYGKVMLVQHKTS------------------GELYALKTIQKRRLI-------ETHKAHTVIAERNSLMKA-SHPFIVRLCFAFQTPQKF
| ...||||| .|||..|.||                    . .||.| .||   |          ..  . |||| ..|  .||||| | .||||..| 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLGLEYASGGELFYHLDKAGALPPSEVRLISAEIALALSYLHSLGIVYRDLKPENVMFDSEGHVKLTDFGLSK-DIVETNSTNTLCGTTEYLSPEVVLHN
|. ..|. |||.|||| ... .| ...|   |||..|| ||||. |.||||||||.. |..||..||||||.| .| ... | | ||| ||| ||| .. 
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

QYDYGVDWWALGCLMYEMLTERTPFENPNRSKMLQDIVHAQPEFPEFLPPDVIEVLSALLSKDPKNRPGID----QLKEFAYF
 .|  |||| |||..|||..   ||.. |.. | . | .    .| .  .|  . .  || ||||.| |      . |.  .|
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 84943.m00183.AA Akt 109-360 42 1.7e-111 357.72 In-house 1-264 (264) Show / Hide 
Range on Protein: 109-360
Range on HMM: 1-264/264
Sequence Identity: 42% (111 aa)

FNIISVIGKGFYGKVMLVQHKTSGELY-ALKTIQKRRLIETHKAHTVIAERNSLMKASHPFIVRLCFAFQTPQKFYLGLEYASGGELFYHLDKAGALPPS
|... |.||| .|||.||. | ....| |.| ..|...|.  .   ...||| | .  ||||| | ..|||..| |. ..|..|||||||| ...  . .
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

EVRLISAEIALALSYLHSLGIVYRD-LKPENVMFDSEGHVKLTDFGLSK-D-IVETNSTNTLCGTTEYLSPEVVLHNQYDYGVDWWA-LGCLMYEMLTER
. |   ||| ||. .||| .|.||| |||||.. |..||..||||||.| . | ..  |.|.||| |||.||. . | ..  ||||. |||.||||.. |
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

TPFENPNRSKMLQDIVHAQPEFP--EFLPPDVIEVLSALLSKDPKNRPG-----IDQLKEFAYF
 || | .. .| . |  .. .||  ... |.    .| ||.||||.|.|     ....|.  .|
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 84943.m00183.AA S_TKc 109-360 32 9.5e-99 335.29 SMART 1-231 (231) Show / Hide 
Range on Protein: 109-360
Range on HMM: 1-231/231
Sequence Identity: 32% (87 aa)

FNIISVIGKGFYGKVMLVQHKTSGELYALKTIQKRRLIETHKAHTVIAERNSLMKASHPFIVRLCFAFQTPQKFYLGLEYASG--GELFYHLDKAGA---
. |. .|||| .|||....|| .|...|.| |            ... |.. |.|  ||.||.|  .||. ...|. .||..|  |.|| ...| |    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LPPSEVRLISAEIALALSYLHSLGIVYRDLKPENVMFDSEGHVKLTDFGLSKDIVETNSTNTLCGTTEYLSPEVVLHNQYDY-GVDWWALGCLMYEM
   .|. ..| . ..|..|| |.||.||..|||||||...|.  |.|..||||.. .      .|.||| .|..|||.   .|..  .|||..||..|||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LTERTPFENPNRSKMLQDIVHAQPEFPEFLPPDVIEVLSALLSKDPKNRPGIDQLKE-------FAYF
|. ..||.  .  .|.. |.          .|.... .. .| |||..||.. .. .         .|
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 84943.m00183.AA RSK 112-360 37 9e-98 331.12 In-house 1-278 (278) Show / Hide 
Range on Protein: 112-360
Range on HMM: 1-278/278
Sequence Identity: 37% (104 aa)

ISVIGKGFYGKVMLVQHK---TSGELYALKTIQKRRLIETHK-AHTVIAERNSLMKAS-HPFIVRLCFAFQTPQKFYLGLEYASGGELFYHLDKAGA---
..| |.| |||| |.. .    .| .|| | ..|. .. . | . .. .||| |.    |||||.|  ||||..|.|| .|| .|||||.|| | .    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LPPSEVRLISAEIALALSYLHSLGIVYRDLKPENVMFDS---EGHVKLTDFGLSKD-IVE-TNSTNTLCGTTEYLSPEVVL---HNQ-YDYGVDWWALGC
.  .|.. . |||.||...||..||..|||||||...|.   |||.||||||..|    . .. |.| |.| ||. ||..    ..  .|  .||| ||.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LMYEMLTERTPFEN---PNRSKMLQDIVHAQ--PEFP--EFLPPDVIEVLSALLSKDPKNRPG-----IDQLKEFAYF
||||||| ..|| .    ||.. .. | ...  ...|  ..| ..  . ....| .||..|.|     ....|. ..|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 84943.m00183.AA AktR 109-360 39 1.7e-92 313.56 In-house 1-268 (268) Show / Hide 
Range on Protein: 109-360
Range on HMM: 1-268/268
Sequence Identity: 39% (106 aa)

FNIISVIGKGFYGKVMLVQHK-TSGELYALKTIQKRRLIETHKAHTVIAERNSLM-KASHPFIVRLCFAFQTPQKFYLGLEYASGGELFYHLDKAGALPP
| .. ..||| .|||.|||.| .....||.| | |  .||  ..| .| ||| .  ...|||||.| ..|||  | .. .||  |||||.|| | . .  
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

SEVRLISAEIALALSYLHSL-GIVYRDLKPENVMFDSEGHVKLTDFGLSK---DIVETNSTNTLCGTTEYLSPEVVLH-NQYDYGVDWWALGCLMYEMLT
...| ..|.| ||| |||.   |.|||||||| . |..||||.|||||||   .....  ....||| ||..||...    ... |||||.|.. |||.|
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

ERTPFENPNRSKMLQDIVHAQ---PEFPEFLPPDVIEVLS-ALLSKDPKNRPG-----IDQLKEFAYF
  .||.. |.  |.| |   |   ...|. . .   . .   || |.|..|.|     ....|.   |
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 84943.m00183.AA p70 109-360 37 1.5e-90 307.15 In-house 1-299 (299) Show / Hide 
Range on Protein: 109-360
Range on HMM: 1-299/299
Sequence Identity: 37% (111 aa)

FNIISVIGKGFYGKVMLVQHKT---SGELYALKTIQKRRLIETHK--AHTV------------------------IAERNSLMKASHPFIVRLCFAFQTP
|  . |.||| ||||..|   |   .| .|| | ..|.  . . |  |||                          |||| |    ||||. | .|||| 
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN

QKFYLGLEYASGGELFYHLDKAGALPPSEVRLISAEIALALSYLHSLGIVYRDLKPENVMFDSEGHVKLTDFGLSKDIVETNST-----------NTLCG
 | || ||| .|||||.|| . | ..   ..   .|| .|| .||..||.||||||||.| .. |||.||||||.|  ..  .             |.||
GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG

TTEYLSPEVVLHNQYDYGVDWWALGCLMYEMLTERTPFENPNRSKMLQDIVHAQ--PEFPEFLPPDVIEVLSALLSKDPKNRPG-----IDQLKEFAYF
| ||  ||...   ..  ||||.|||||| |||   ||   || |    |  .   .. |  | ..    . .|| ..|. | |     . . .| ..|
TIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF
Kinase 84943.m00183.AA PKA 109-360 38 2.6e-90 306.34 In-house 1-263 (263) Show / Hide 
Range on Protein: 109-360
Range on HMM: 1-263/263
Sequence Identity: 38% (101 aa)

FNIISVIGKGFYGKVMLVQHKTSGELYALKTIQKRRLIETHKAHTVIAERNSLMKASHPFIVR-LCFAFQTPQKFYLGLEYASGGELFYHLDKAGALPPS
|.|| ..|.| .|.|||..||.||. ||.|.. |.. . .   . |. |.| |.  .|||||. . . ||.... |. .||..|||.|..| | | .. .
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

EVRLISA-EIALALSYLHSLGIVYRDLKPENVMFDSEGHVKLTDFGLSKDIVETNSTNTLCGTTEYLSPEVVLHN-QYDYGVDWWALGCLMYEMLTERTP
. ... | .| ||| ||||. |.|||||||| . |..||.|.|||| .| ...   | ||||| ||| ||...    .  .|||||||.| ||||.  .|
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPP

FENP--NRSKMLQDIVHAQPEFPEFLPPDV---IEVLSALLSKDPKNRP-----GIDQLKEFAYF
|..   .  .. . |. .. .||... .|.      .. ||..|.. |      |... |.   |
FYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 84943.m00183.AA PKC 109-360 35 1.6e-86 280.41 In-house 1-262 (262) Show / Hide 
Range on Protein: 109-360
Range on HMM: 1-262/262
Sequence Identity: 35% (94 aa)

FNIISVIGKGFYGKVMLVQHKTSGELYALKTIQKRRLIETHKAHTVIAERNSLMKAS-HPFIVRLCFAFQTPQKFYLGLEYASGGELFYHLDKAGALPPS
|| . |.||| .|||||. .| . |.|| | . |   |...    . .|.  |  |. ||| . |   |||. . .  .||  || | .|  ... .. .
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

EVRLISAEIALALSYLHSLGIVYRDLKPENVMFDSEGHVKLTDFGLSKD-IVETNSTNTLCGTTEYLSPEVVLHNQYDYGVDWWALGCLMYEMLTERTPF
  |  .|||..|| .||. ||.||||| .||. |.|||.|..|||..|. ... . |.| ||| .|..||..   .|   |||||.| |||||.  . ||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

ENPNRSKMLQDIVHAQPEFPEFLPPDVIEVLSALLSKDPKNRPGI--------DQLKEFAYF
.  .   . | | | .| .|  |  .  ....... |.|..| |         .  .| ..|
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase 84943.m00183.AA Pkinase 109-360 29 9.8e-84 289.29 Pfam 1-293 (293) Show / Hide 
Range on Protein: 109-360
Range on HMM: 1-293/293
Sequence Identity: 29% (88 aa)

FNIISVIGKGFYGKVMLVQHKTSGELYALKTIQKRRLIE-THKAHTVIAERNSLMKASHPFIVRLCFAFQTPQKFYLGLEYASGG----ELFYHLD--KA
. |...||.| .|.| . .|| .|...|.|.| ||.  .  ...|. ..|   . . .||.||||  .|..... |. .||. ||    .|| ..   . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GAL--PPSEVRLISAEIALALSYLHSLGIVYRDLKPENVMFDSEGHV----KLTDFGLSKD--IVETNSTNTLCGTTEYLSPEVVL-HNQYDYGVDWWAL
|..  .. |.. .  .|. .| |.|| ||..|||||||...|..||.    |..||||.|   .     ..|.||| .|..|||.. .. |.. ||.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCLMYEMLTERTPFENP------NRSKMLQDIVHAQPEFPEFLP---------------------PDVIEVLSALLSKDPKNRPGIDQLKEFAYF
||..||||. |.|| .       .  .|.. | .....|... .                     .. ..... .| |||| ||...|...  .|
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 84943.m00183.AA Ciliate-E2-Unclassified 109-360 25 3.7e-80 272.61 In-house 1-352 (352) Show / Hide 
Range on Protein: 109-360
Range on HMM: 1-352/352
Sequence Identity: 25% (88 aa)

FNIISVIGKGFYGKVMLVQHKTSGELYALKTIQKRRLIETHKAHTV---------IAERN-------------SLMKASHPFIVRLCFAFQTPQKFYLGL
..|| .||.| .||| ..|||  ...||.|.. | . .  ..  ..         . ...             .|    |||||.....||. |..|. .
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYASGGELFYHLDK-----------------AGALPPSEVR-----LISAEIALALSYLHSLG-IVYRDLKPENVMFDSEG---HVKLTDFGLSK-----
||. ||.|.... |                    ..  ...      . |.| ..|.|||. . |..||.||||..||..|   ..|..|||.||     
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

-----------DIVETNSTNTLCGTTEYL----SPEVVLHNQYD----YGVDWWALGCLMYEMLTERTPFENPNRSK----------------MLQDIVH
           .|   . ..| ||| .|.    .|||   ..||    | .|.|.||...||||. . ||. .|. .                ..|.|  
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

AQPEFPEFLP--------PDVIEVLS----ALLSKDPKNRPGIDQLKEFAYF
 ...||.| .        | ... ..     .| |.|..|....|...  .|
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 84943.m00183.AA RSK 109-360 35 6.4e-79 268.49 In-house 1-271 (271) Show / Hide 
Range on Protein: 109-360
Range on HMM: 1-271/271
Sequence Identity: 35% (97 aa)

FNIISVIGKGFYGKVMLVQHK---TSGELYALKTIQKRRLIETHKAHTVIAERNSLMKASHPFIVRLCFAFQTPQKFYLGLEYASGGELFYHLDKAGALP
......||.| ..|| ... .    .. .|| | |.|  .  . .     .||. |    |||||.|  .||. .| |. .. . ||.|| .| | . ..
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFS

PSEVRLISAEIALALSYLHSLGIVYRDLKPENVMFDSE----GHVKLTDFGLSKDIVETNS-TNTLCGTTEYLSPEVVLHNQYDYGVDWWALGCLMYEML
 .||. . ||||||. ||||.|||.|||||||. .|.|    ||.|..|||..|     |  . | |.| .|. |||.    .|  .||| .| ||||||
EREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEML

TERTPFENPNRSKMLQDIVHAQPEF-------PEFLPPDVIEVLSALLSKDPKNRPGI-----DQLKEFAYF
| .||| | .|  . . |. ..          ..|. .   ..|...|  || ||.|       | |. ..|
TGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase 84943.m00183.AA TyrKc 109-358 20 2.8e-16 40.49 SMART 1-280 (280) Show / Hide 
Range on Protein: 109-358
Range on HMM: 1-280/280
Sequence Identity: 20% (58 aa)

FNIISVIGKGFYGKVMLVQHKTSGELYALKTIQKRRLIETHKAHTVIAERNSLMKA--SHPFIVRLCFAFQTP-------QKFYLGLEYASGGELFYHL-
   . ..| |..|.|.. . |   .  | |....            . | . ..|   .|| ||||  .  ..       .  .. .||...| |  .| 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

DKAGALPPSEVRLISAEIALALSYLHSLGIVYRDLKPENVMFDSEGHVKLTDFGLSKDIVET------NSTNTL----CGTT----EYLSPEVVLHNQYD
.. . |....   ..  ||   .|||| ... |||   |.. .....|| .|||||.|| .        .. .     .| |      ..||.  .. . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

YGVDWWALGCLMYEMLTE-RTPFEN-----PNRSKMLQDIVHA-QPEFPEF--------LPPDVIEVLSALLSKDPKNRPGIDQLKEFA
   | |. | .|.|..|   .| ..      . . ..... .   .. |.          |... .. .     ||..||   ...|. 
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 84943.m00183.AA Pkinase_Tyr 186-308 25 1.2e-08 29.92 Pfam 86-218 (270) Show / Hide 
Range on Protein: 186-308
Range on HMM: 86-218/270
Sequence Identity: 25% (34 aa)

LEYASGGELFYHLDK----AGALPPSEVRLISAEIALALSYLHSLGIVYRDLKPENVMFDSEGHVKLTDFGLSKDI----VE-TNSTNTLCGTTEYLSPE
.||. .| |  .| |     ..|....   ....|| ...||.| ... |||   |.. .....|| .||||..||       . ....       ..||
MEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPE

VVLHNQYDYGVDWWALGCLMYEMLT-ERTP-FEN
.  .. .    | |. | ||.|..|  ..| ...
CINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPG
Kinase 84943.m00183.AA S_TK_X 361-418 24 3e-06 28.01 SMART 1-79 (79) Show / Hide 
Range on Protein: 361-418
Range on HMM: 1-79/79
Sequence Identity: 24% (19 aa)

KCLDFNKVFR--REYTPEYIPPHT----DKLTPLNFDSEFTEDKPVDSPVPLMLPD---------------FPGFSYNA
. .|..|...  .|..| ..|. .    .     ||| |||| .|...|.. .| .               |.||.|..
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 84943.m00183.AA Pkinase_C 389-420 35 6.5e-05 20.63 Pfam 10-46 (46) Show / Hide 
Range on Protein: 389-420
Range on HMM: 10-46/46
Sequence Identity: 35% (13 aa)

NFDSEFTEDKPVDSP-----VPLMLPDFPGFSYNAFG
||| |||. .|.|.|      . .   | ||.| .. 
NFDPEFTDEPPMDTPPDWRMSSGDQEPFRGFTYVNPD
Kinase 84943.m00183.AA Pkinase_Tyr 109-125 23 1.613575 2.38 Pfam 1-17 (270) Show / Hide 
Range on Protein: 109-125
Range on HMM: 1-17/270
Sequence Identity: 23% (4 aa)

FNIISVIGKGFYGKVML
  .. ..|.| .|.|..
ITFGKKLGEGAFGEVYK