Gene 96732.m00538 (T.vaginalis)

96732.m00538

Species: T.vaginalis
Alias: 96732.m00538, TvagK0440
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
96732.m00538.AA Protein None 442 None Fasta, JSON
96732.m00538.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 96732.m00538.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH 96732.m00538.AA PH 7-102 26 1.9e-09 38.64 SMART 1-82 (82) Show / Hide 
Range on Protein: 7-102
Range on HMM: 1-82/82
Sequence Identity: 26% (25 aa)

GSYQGTLKKKGSFFGIWNNCYCEVCNSEFIVYKNYESKIIEKRIPIGVDTTVAPLEDDKRKFKIDSPGINTFVFLSESEEVTMEWILAIKSQAIND
  ..|.|.||.  .  |  ... ..|. .. ||.       ..||.    || . .     |.| . .  |..|  ||||   ||. ||.. . | 
VIKEGWLYKKS--K-RWKKRWFVLFNDCLYYYKDK---KPKGSIPLSDC-TVRE-P----CFEIHH-DR-TYYFQCESEEEMQEWMQAIQKAIHNN
PH 96732.m00538.AA PH 7-100 27 7.3e-09 34.6 Pfam 1-92 (92) Show / Hide 
Range on Protein: 7-100
Range on HMM: 1-92/92
Sequence Identity: 27% (26 aa)

GSYQGTLKKKGSFFGIWNNCYCEVCNSEFIVYKNYESKIIEKRIPIGVDTTVAPLED--DKRKFKIDSPGINTFVFLSESEEVTMEWILAIKSQAI
  ..| |.||| ... |  ... ..|.  . ||.   .   . ||.  | .| ...|  ..  |.| . . .|..|  ||||   .|. ||.| . 
VIKEGWLHKKG-KRKSWKKRWFVLFNNCLYYYKDDK-YRPKGSIPL-SDCQVTKVPDNKRPHCFQIRT-DRRTYYFQAESEEEMNDWMQAIQSACR
Kinase 96732.m00538.AA AGC 110-361 32 1.3e-159 416.31 In-house 1-395 (395) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-395/395
Sequence Identity: 32% (129 aa)

FNIISVLGRGYYGKVMLVQKK------GTKNLYAIKSIHKAR-LIQTR--KVHTVFSE------------RNILMKVK----------HPFIVS-LSFAF
|... |.|.| .|||.||.||      .|. .||.| . |..  ....  .|. . .|            ||||.|..          |||||. | ..|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QSMSK--FYLGMQYIP---------GG-ELFRYLS---KVGKLQMSEVRFYAAE-------IGLALSHLHS-NGIIYRD-LKPENILLDEEGHIKLTDFG
|. ..   |. |.|.|         || ||| .|    | |..  ...||||||       | ||| .||| .|||.|| ||||||||||.|||||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LAKDMSFDS---------------------------------------------------ATSTFCG--TVEYLAPEIVRREPYGMAIDWWS--YGCLVY
|.| .  |                                                     |.||||  | ||.||||.    || | ||||  .||| |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EFIFGHTPFYDEN----------RAKIFMRIP------ADQPYYP----------SDFDPNVSDFINQLLSKDPETRAT----------FDTLKDHPFW
|...|..|||..|          ....| .|        ... .|          . |.|.  |.|..|| |||| | .          .. .|.||. 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 96732.m00538.AA Akt 110-361 44 5.2e-122 391.84 In-house 1-264 (264) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-264/264
Sequence Identity: 44% (118 aa)

FNIISVLGRGYYGKVMLVQKKGTKNLY-AIKSIHKARLIQTRKVHTVFSERNILMKVKHPFIVSLSFAFQSMSKFYLGMQYIPGGELFRYLSKVGKLQMS
|... |||.| .|||.||.|| |...| |.|.. | ..|| ..|  .. ||||| ...|||||.| ..||.  | |. |.|..||||| .|.. ..   .
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

EVRFYAAEIGLALSHLHSNGIIYRD-LKPENILLDEEGHIKLTDFGLAK-D-MSFDSATSTFCGTVEYLAPEIVRREPYGMAIDWWS-YGCLVYEFIFGH
. |||.||| ||. ||||..||||| |||||||.|..|||.||||||.| . .. .  | ||||| |||||||     ...| |||.  ||. ||...| 
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

TPFYDENRAKIFMRIPADQPYYP--SDFDPNVSDFINQLLSKDPETRA-----TFDTLKDHPFW
 |||.... . |  |   .  .|  . ..|.  |.|..||.|||. |      . . .|.||. 
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 96732.m00538.AA SGK 110-361 39 6.30000000001e-117 362.74 In-house 1-283 (283) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-283/283
Sequence Identity: 39% (113 aa)

FNIISVLGRGYYGKVMLVQKKGT------------------KNLYAIKSIHKARLI-------QTRKVHTVFSER-NILMKVKHPFIVSLSFAFQSMSKF
| ...|.| | .|||..|..|..                  . .||.| . |.  |       .  ..  . .|| .|| ..||||||.| .|||   | 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLGMQYIPGGELFRYLSKVGKLQMSEVRFYAAEIGLALSHLHSNGIIYRDLKPENILLDEEGHIKLTDFGLAK-DMSFDSATSTFCGTVEYLAPEIVRRE
|. | |. |||.| .| . ...  ...||||||| .|| .|||  |||||||||||||| .||..||||||.| ..     |.|||||.||||||. | .
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

PYGMAIDWWSYGCLVYEFIFGHTPFYDENRAKIFMRIPADQPYYPSDFDPNVSDFINQLLSKDPETR--AT--FDTLKDHPFW
|.. . |||. ||. ||...|  |||. |..  .  |       |  . .  .| |..|| |||. |  .   |   |.||| 
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 96732.m00538.AA AktR 110-361 42 6.1e-114 384.84 In-house 1-268 (268) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-268/268
Sequence Identity: 42% (115 aa)

FNIISVLGRGYYGKVMLVQKK-GTKNLYAIKSIHKARLIQTRKVHTVFSERNILM-KVKHPFIVSLSFAFQSMSKFYLGMQYIPGGELFRYLSKVGKLQM
| .. .||.| .|||.|||||  .. .||.|.|.|  .|. .. | .  ||||.  ...||||| | ..||. .| .. |.|.||||||..|.| .|.  
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

SEVRFYAAEIGLALSHLHSN-GIIYRDLKPENILLDEEGHIKLTDFGLAK---DMSFDSATSTFCGTVEYLAPEIVRR-EPYGMAIDWWSYGCLVYEFIF
...|||.|.| ||| .||..  |||||||||||||||.||.|.|||||.|   .|. |  . .||||.||.|||.... .... ..|||. |...|| ..
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GHTPFYDENRAKIFMRIPADQ---PYYPSDFDPNVSDFIN-QLLSKDPE---T--RATFDTLKDHPFW
|..|||..|.  .| .|   |   . |||.| ..  |.|. .|| |.|.   .  ..... .|.||. 
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 96732.m00538.AA PKA 110-361 43 2e-109 369.84 In-house 1-263 (263) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-263/263
Sequence Identity: 43% (114 aa)

FNIISVLGRGYYGKVMLVQKKGTKNLYAIKSIHKARLIQTRKVHTVFSERNILMKVKHPFIV-SLSFAFQSMSKFYLGMQYIPGGELFRYLSKVGKLQMS
|.|| .||.| .|.|||...|...| ||.| . |.. .... |. | .|.|||. .|||||| .. . ||  .. |. | |.||||.| || |.|..  .
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

EVRFYAA-EIGLALSHLHSNGIIYRDLKPENILLDEEGHIKLTDFGLAKDMSFDSATSTFCGTVEYLAPEIVRRE-PYGMAIDWWSYGCLVYEFIFGHTP
. .|||| .| |||  |||  ||||||||||||.|..||||.|||| || .     |.| ||| |||||||. .. ..| ..|||. |.|.||. .|..|
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPP

FYDE--NRAKIFMRIPADQPYYPSDFDPNV---SDFINQLLSKDPETRA-TFDT----LKDHPFW
|||.  . ..|. .| . .  .|. ||...    |.|..||..|.. |  ...      |.|.. 
FYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 96732.m00538.AA RSK 113-361 42 2.7e-106 359.46 In-house 1-278 (278) Show / Hide 
Range on Protein: 113-361
Range on HMM: 1-278/278
Sequence Identity: 42% (117 aa)

ISVLGRGYYGKVMLVQKK---GTKNLYAIKSIHKARLIQTRK-VHTVFSERNILMKVK-HPFIVSLSFAFQSMSKFYLGMQYIPGGELFRYLSKVGK---
..|||.| |||| |..|.    |. .|| | ..|| ..|. | . ... |||||. .. |||||.|  |||  .|.|| |.|..|||||. |.| .    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LQMSEVRFYAAEIGLALSHLHSNGIIYRDLKPENILLDE---EGHIKLTDFGLAKDMSFD--SATSTFCGTVEYLAPEIVR---REP-YGMAIDWWSYGC
.  .|..||.||| ||..|||. |||.|||||||||.|.   ||||||||||..| .. |  . | |||.|.||.|||...   ..  .. | |||| |.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LVYEFIFGHTPFYD---ENRAKIFMRIPADQ--PYYP--SDFDPNVSDFINQLLSKDPETRAT-----FDTLKDHPFW
| ||  .|..||.    .||..|. ||   .  .  |  .   ..  |.|...| .||. | .      . .|.||..
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 96732.m00538.AA S_TKc 110-361 37 5e-100 339.52 SMART 1-231 (231) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-231/231
Sequence Identity: 37% (101 aa)

FNIISVLGRGYYGKVMLVQKKGTKNLYAIKSIHKARLIQTRKVHTVFSERNILMKVKHPFIVSLSFAFQSMSKFYLGMQYIPG--GELFRYLSKVGK---
. |. ..|.| .|||.....|.|. ..||| |.           .. .|..||.| .||.|| |  .||. ...|. | |..|  |.||.|. | |.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LQMSEVRFYAAEIGLALSHLHSNGIIYRDLKPENILLDEEGHIKLTDFGLAKDMSFDSATSTFCGTVEYLAPEIVRREPYGM-AIDWWSYGCLVYEF
   .   ..|||...| .|| ..||.|||.||||||||||||  |||..|||||. .      .||||| .|.|||..   .||  ..|||| ||..||.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

IFGHTPFYDENRAKIFMRIPADQPYYPSDFDPNVSDFINQLLSKDPETRATFDTLKD-------HPFW
. | .||.  . ...| .|           .| . |||...| |||| | |   .         ||. 
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 96732.m00538.AA PKC 110-361 41 7.7e-97 314.44 In-house 1-262 (262) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-262/262
Sequence Identity: 41% (108 aa)

FNIISVLGRGYYGKVMLVQKKGTKNLYAIKSIHKARLIQTRKVHTVFSERNIL-MKVKHPFIVSLSFAFQSMSKFYLGMQYIPGGELFRYLSKVGKLQMS
|| . |||.| .|||||. .|||. .|||| . |   ||.  |  .  |. .|    |||| ..|   ||.|.. .  | |. || |     ...... .
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

EVRFYAAEIGLALSHLHSNGIIYRDLKPENILLDEEGHIKLTDFGLAKD-MSFDSATSTFCGTVEYLAPEIVRREPYGMAIDWWSYGCLVYEFIFGHTPF
  ||||||| .||  ||..|||||||| .|.|||.|||||..|||..|. |  .. ||||||| .|.||||.. ..|| ..|||..| | ||.  |. ||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

YDENRAKIFMRIPADQPYYPSDFDPNVSDFINQLLSKDPETRATF--------DTLKDHPFW
  |.   .|  |  |.|.|| ..    .. . ... |.||.|           .  ..||| 
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase 96732.m00538.AA p70 110-361 39 3.5e-95 322.51 In-house 1-299 (299) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-299/299
Sequence Identity: 39% (118 aa)

FNIISVLGRGYYGKVMLVQKKG---TKNLYAIKSIHKARLIQTRK--VHTV------------------------FSERNILMKVKHPFIVSLSFAFQSM
|  . |||.| ||||..| |     |  .|| | . ||  . . |   ||                         | |||||  ||||||. | .|||  
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN

SKFYLGMQYIPGGELFRYLSKVGKLQMSEVRFYAAEIGLALSHLHSNGIIYRDLKPENILLDEEGHIKLTDFGLAKDMSFDSAT-----------STFCG
.| ||  .|..|||||  | . | .    ..||..|| .|| |||. |||||||||||..|.. ||..|||||| |    |.|             ||||
GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG

TVEYLAPEIVRREPYGMAIDWWSYGCLVYEFIFGHTPFYDENRAKIFMRIPADQ--PYYPSDFDPNVSDFINQLLSKDPETRAT-----FDTLKDHPFW
| || ||||..|  .. |.|||| ||| |    |  ||  |||.|.   |      .  |    .   | |..|| ..| .| .         . |||.
TIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF
Kinase 96732.m00538.AA RSK-Unclassified 110-361 38 2e-94 296.98 In-house 1-283 (283) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-283/283
Sequence Identity: 38% (109 aa)

FNIISVLGRGYYGKVMLVQKKGTKNLYAIKSIHKARLIQTRKVHTVFSERNILMKVKHPFIVSLSFAFQSMSKFYLGMQYIPGGELFRYLS--KVGKLQM
|  .  .|.|  ||| ||.||.|. .||.|  || ..|. .|.  |  |.||.   .||||| | ..||.  . || |.| .||..|| |   |  ..  
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

SEVRFYAAEIGLALSHLHSNGIIYRDLKPENILLDEEGHIKLTDFGLAKDM----------------------SFDSATSTFCGTVEYLAPEIVRREPYG
 .|||||.|. .|| .||  ..|||||||.||.|. |||..||||.| ..                       .  . |  ||||.||||||..||   .
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHT

MAIDWWSYGCLVYEFIFGHTPFYDENRAKIFMRIPADQPYYP--SDFDPNVSDFINQLLSKDPETR----AT-FDTLKDHPFW
 |.|||  | ..||  || .|.| .|.  .|  |   .   |  |    |  | |  || . |  |        |  | ||| 
KAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF
Kinase 96732.m00538.AA PDK1 110-361 34 5.6e-92 282.02 In-house 1-307 (307) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-307/307
Sequence Identity: 34% (105 aa)

FNIISVLGRGYYGKVMLVQKKGT----KNLYAIKSIHKARLIQTRKVHTVFSERNILMKVK-----HPFIVSLSFAFQSMSKFYLGMQYIPGGELFRYLS
| .....|.| |..|.|.  | |    .. ||||   |  .|  .||  |. |..|. .       ||.|| |.| ||. .. | .. | |.|.|  |. 
FIFGKNIGEGSYSTVYLAREKETKNDENKMYAIKICEKRYIIREKKVKYVHREKEIMCHLNNECNGHPGIVKLYFTFQDEQCLYFVLEYCPNGDLLHYMK

K--VGKLQMSEVRFYAAEIGLALSHLHSNGIIYRDLKPENILLDEEGHIKLTDFGLA---KDMSFD---------------------------SATSTFC
|  .|.. |. .||||||| .|| |||||||| |||||||||||...||..|||| |   | .. .                           .  ..|.
KQPFGSFDMDCCRFYAAEIIDALEHLHSNGIIHRDLKPENILLDKDMHIMITDFGTAGFDKILPEYQSQQQNQFQQQFQQHNKGMDKPEEDKQTRCKSFV

GTVEYLAPEIVRREPYGMAIDWWSYGCLVYEFIFGHTPFYDE-----NRAKIFMRIPADQPYYPSD--FDPNVSDFINQLLSKDPETRAT-------FDT
|| ||  ||    .. . . | |..||..| .. | .|| ..     |  ..| .| . | ..| .  |.|...| . .|| .|| .| |       ...
GTAEYVSPELLTDKECTPSCDIWALGCIIYQMVAGQPPFRGMNDATNNEYHTFQKIMKCQYDFPDNFRFPPCAKDLVKKLLVRDPNDRLTSCDECGGYQQ

LKDHPFW
.| ||| 
IKAHPFF
Kinase 96732.m00538.AA Pkinase 110-361 32 6.3e-87 299.9 Pfam 1-293 (293) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-293/293
Sequence Identity: 32% (97 aa)

FNIISVLGRGYYGKVMLVQKKGTKNLYAIKSIHKARLIQTRKVHTVF-SERNILMKVKHPFIVSLSFAFQSMSKFYLGMQYIPGG----ELFRYLS--KV
. |....|.| .|.| . ..|||  ..|.| | | .     ... .  ||  |. ...||.|| |  .|.. .. |. | | .||    .||.|.|  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GKL--QMSEVRFYAAEIGLALSHLHSNGIIYRDLKPENILLDEEGHI----KLTDFGLAKD--MSFDSATSTFCGTVEYLAPEIVR-REPYGMAIDWWSY
|..  .. |..||. .|  .| ..||.|||.|||||||||.|..|||    |..||||||      .| ..||||| .|.|||..| ...|| ..|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCLVYEFIFGHTPFYDE------NRAKIFMRIPADQPYYPSDFD---------------------PNVSDFINQLLSKDPETRATFDTLKDHPFW
||..||...|..||...      .  ... ||   .. .... .                     ..  |||. .| |||. | |.. .. ||..
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 96732.m00538.AA TyrKc 110-361 21 8.2e-16 32.95 SMART 1-280 (280) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

FNIISVLGRGYYGKVMLVQKKGTKNLYAIKSIHKARLIQTRKVHTVFSERNILMKV--KHPFIVSLSFAFQSM-------SKFYLGMQYIPGGELFRYLS
   . .||.| .|.|.. . |      |.|....        .    .| .|..|.  .|| || |  .  .           .. | | |.| |  || 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KVGK-LQMSEVRFYAAEIGLALSHLHSNGIIYRDLKPENILLDEEGHIKLTDFGLAKDMSFD--------SATSTF--CGT----VEYLAPEIVRREPYG
| .. |.|..   ..  |    ..|||...| |||   |.|..|....| .||||..|   |          ...   .|     .  .|||  .   . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

MAIDWWSYGCLVYEFI-FGHTPFYD-----ENRAKIFMRIPAD-QPYYPSD--------FDPNVSDFINQLLSKDPETRATFDTLKDHPFW
 . | ||.| . .|   .| .| ..      . . .. .. .   .  | .          . . . . |    ||| | || ..  | ..
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 96732.m00538.AA Pkinase_Tyr 110-258 29 5.2e-09 31.13 Pfam 1-161 (270) Show / Hide 
Range on Protein: 110-258
Range on HMM: 1-161/270
Sequence Identity: 29% (47 aa)

FNIISVLGRGYYGKVMLVQKK----GTKNLYAIKSI-HKARLIQTRKVHTVFSERNILMKV-KHPFIVSLSFAFQ-SMSK--FYLGMQYIPGGELFRYLS
  .. .||.| .|.|..   |    .||   |.|.. ..|   |  .    ..| .|...  .|| ||.|  .          |. | | |.| |  || 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQN-CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

K----VGKLQMSEVRFYAAEIGLALSHLHSNGIIYRDLKPENILLDEEGHIKLTDFGLAKDM
|     ..| |..   ....|  ....|.|...| |||   |.|..|....| .|||||.|.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI
Kinase 96732.m00538.AA S_TK_X 362-422 24 5.8e-08 33.7 SMART 1-79 (79) Show / Hide 
Range on Protein: 362-422
Range on HMM: 1-79/79
Sequence Identity: 24% (19 aa)

EGMDFDEVLE--RKVEPLYVPPID----DKFNPENFDSAFTR----ETPCDSVATPAIEGHT--------EFNGFSFVG
 | |.| ..   ...|| ..|.|     . .  .|||  ||.    .||.|.......            .| ||..| 
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 96732.m00538.AA Pkinase_C 389-424 30 1e-05 23.51 Pfam 9-46 (46) Show / Hide 
Range on Protein: 389-424
Range on HMM: 9-46/46
Sequence Identity: 30% (12 aa)

ENFDSAFTRETPCDSV---ATPAIEGHTEFNGFSFVGSM
.|||  ||.|.| |..        . . .| ||..| ..
SNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFTYVNPD