Gene 82039.m00042 (T.vaginalis)

82039.m00042

Species: T.vaginalis
Alias: 82039.m00042, TvagK0370
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
82039.m00042.AA Protein None 461 None Fasta, JSON
82039.m00042.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of 82039.m00042.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH 82039.m00042.AA PH 10-106 19 0.000141 22.45 SMART 1-82 (82) Show / Hide 
Range on Protein: 10-106
Range on HMM: 1-82/82
Sequence Identity: 19% (19 aa)

LSIMSWLRQKTAAFRFDRQLYCVVTDTEFVCYSDEQMTKIDKQIPLTQISKVSPLPASSRPGFSFQLPNGS-TLIFYDTSIHQAQKWICALRTEPPSE
. .  ||..|.  .   .. ..|...  ...| |.   |  . |||. . .|.. |       .|.. . . |..|.  |  ..|.|. |..    . 
VIKEGWLYKKS--K-RWKKRWFVLFNDCLYYYKDK---KPKGSIPLSDC-TVRE-P-------CFEIHH-DRTYYFQCESEEEMQEWMQAIQKAIHNN
Kinase 82039.m00042.AA AGC 113-366 29 3.4e-154 402.01 In-house 1-395 (395) Show / Hide 
Range on Protein: 113-366
Range on HMM: 1-395/395
Sequence Identity: 29% (118 aa)

FNLKKVIGRGASGKVYLAEKK------STGERFAIKAIRKDS-LPQKK--RVSRVRAE------------RNALMRAK----------HQFITR-LFYAF
|...||||.|. |||||..||      .||. .|.| ..|.    .||   | .. .|            || |....          |.||.. |.|.|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QSPTK--LYFVMEYEA---------GG-DLRHHM--D-QNTSFSLPQIRIYLAE-------LALALKTLHG-LGIVYRD-LKPENILLDAEGHIKLADFG
|....  |||||||           || .| .|.  . .. .|. ...|.|.||       ..|||  ||  .||..|| |||||||||..|||||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LAKEINSESD---------------------------------------------------ATSICG--TCEYIAPEMLRSQPQTFAVDWWS--FGVIAF
|.||.... .                                                   ....||  | ||.|||.|     ..|.||||  .|.. .
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

QLLCNRLPFASANPQ----------RLFQLIM------NNQPRIP----------NNLDSSAQSFLQQLLNKEPAKRLGSVG--------TDITHHPFF
..|. . || . |||           .||.||      |.....|           .... |......||.|.|.||||. |         .|  ||.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 82039.m00042.AA Akt 113-366 41 3.3e-119 382.74 In-house 1-264 (264) Show / Hide 
Range on Protein: 113-366
Range on HMM: 1-264/264
Sequence Identity: 41% (110 aa)

FNLKKVIGRGASGKVYLAEKKSTGERF-AIKAIRKDSLPQKKRVSRVRAERNALMRAKHQFITRLFYAFQSPTKLYFVMEYEAGGDLRHHMDQNTSFSLP
|...||.|.|. |||.|..||.|.. . |.|...|| . ||. |  . .||| | . .|.||. | |.||...||||||.|  ||.|  |. .   || .
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

QIRIYLAELALALKTLHGLGIVYRD-LKPENILLDAEGHIKLADFGLAKEI-NSE-SDATSICGTCEYIAPEMLRSQPQTFAVDWWS-FGVIAFQLLCNR
..| | ||. ||.  ||  .|.||| |||||||.|..|||.|.||||.||.  ..   ....||| ||.|||.|  . .| |||||. .|.. . ..| |
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

LPFASANPQRLFQLIMNNQPRIP--NNLDSSAQSFLQQLLNKEPAKRLG-SVG--TDITHHPFF
.|| . . ...|..|.|.. ..|  ....  ..... .|||| | ||||   .   .|  ||.|
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 82039.m00042.AA SGK 113-366 39 1e-108 336.91 In-house 1-283 (283) Show / Hide 
Range on Protein: 113-366
Range on HMM: 1-283/283
Sequence Identity: 39% (111 aa)

FNLKKVIGRGASGKVYLAEKKST------------------GERFAIKAIRKDSLP-------QKKRVSRVRAER-NALMRAKHQFITRLFYAFQSPTKL
| ..|||| |  ||||....|..                  .  .|.| ..|..         .|| .  . ||| ..|   || ||  | |||| ..||
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YFVMEYEAGGDLRHHMDQNTSFSLPQIRIYLAELALALKTLHGLGIVYRDLKPENILLDAEGHIKLADFGLAK-EINSESDATSICGTCEYIAPEMLRSQ
||||.|  ||..  |.    .|. .. |.| ||...||  || . |.||||||||||||..||..| ||||.| .|  .   ...||| || |||.|| |
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

PQTFAVDWWSFGVIAFQLLCNRLPFASANPQRLFQLIMNNQPRIPNNLDSSAQSFLQQLLNKEPAKRLGSV--GTDITHHPFF
|   .||||. | . . ..    || | | | ... |.|   .|| .  ..| . .|.||.|.| ||||.   . .|  ||||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 82039.m00042.AA PKC 113-366 44 1.4e-103 336.66 In-house 1-262 (262) Show / Hide 
Range on Protein: 113-366
Range on HMM: 1-262/262
Sequence Identity: 44% (116 aa)

FNLKKVIGRGASGKVYLAEKKSTGERFAIKAIRKDSLPQKKRVSRVRAERNALMRA-KHQFITRLFYAFQSPTKLYFVMEYEAGGDLRHHMDQNTSFSLP
||. ||.|.|  ||| |||.| | | .|||...||   |   |  ...|.  |  | || | | |.  ||.. .|.|||||  |||| .|. |   |...
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

QIRIYLAELALALKTLHGLGIVYRDLKPENILLDAEGHIKLADFGLAKE-INSESDATSICGTCEYIAPEMLRSQPQTFAVDWWSFGVIAFQLLCNRLPF
. | | || ..||. ||  ||.||||| .|.|||.|||||.||||..|| .. .. ... ||| .||||| |. |. ...||||.|||  ..... . ||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

ASANPQRLFQLIMNNQPRIPNNLDSSAQSFLQQLLNKEPAKRLGSVGT------DITHHPFF
   .   ||| ||. .|..|  |   | | ......|.|.||||.  .      ||. ||||
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase 82039.m00042.AA RSK 116-366 37 5.9e-97 328.4 In-house 1-278 (278) Show / Hide 
Range on Protein: 116-366
Range on HMM: 1-278/278
Sequence Identity: 37% (104 aa)

KKVIGRGASGKVYLAEKK---STGERFAIKAIRKDSLPQKKR-VSRVRAERNALMRAK-HQFITRLFYAFQSPTKLYFVMEYEAGGDLRHHMDQNTS---
 || |.|. |||.|  |.    ||  .| | ..|  . |... . ....||| |.| . |.|| .|.|||| ..||| .|||  ||.|  |  .  .   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FSLPQIRIYLAELALALKTLHGLGIVYRDLKPENILLDA---EGHIKLADFGLAKE-INS-ESDATSICGTCEYIAPEMLR---SQP-QTFAVDWWSFGV
||    ..|.||..||.. || .||..|||||||||.|    |||||| |||..|.  .. .. . . |.| ||.|||||.    |   . |.||||.||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

IAFQLLCNRLPFAS---ANPQRLFQLIMNNQ--PRIP--NNLDSSAQSFLQQLLNKEPAKRLGSV---GTDITHHPFF
. . .|  ..||..   .|.. ... |....  ...|  ..|   |.......| ..|.||||.      .|  ||.|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 82039.m00042.AA S_TKc 113-366 34 2.2e-96 327.45 SMART 1-231 (231) Show / Hide 
Range on Protein: 113-366
Range on HMM: 1-231/231
Sequence Identity: 34% (92 aa)

FNLKKVIGRGASGKVYLAEKKSTGERFAIKAIRKDSLPQKKRVSRVRAERNALMRAKHQFITRLFYAFQSPTKLYFVMEYEAG--GDLRHHMDQNTS---
. . ..||.|| ||||.. .|.||...||| |.           ..| |.. |.. .| .| .|...||. ..||.||||  |  |||....... .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FSLPQIRIYLAELALALKTLHGLGIVYRDLKPENILLDAEGHIKLADFGLAKEINSESDATSICGTCEYIAPEMLRSQPQTF-AVDWWSFGVIAFQL
   |.  ..| |......||. .| .||..|||||||||||   |||..|||||...      |..||| .|.|||.|   . .. ..||||.|.| . .
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LCNRLPFASANPQRLFQLIMNNQPRIPNNLDSSAQSFLQQLLNKEPAKRLGSVGTDI--TH---HPFF
|| . ||   ..|..|..|.          ...| .|....|.|.|.||..         .   ||.|
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 82039.m00042.AA AktR 113-366 39 9e-91 307.87 In-house 1-268 (268) Show / Hide 
Range on Protein: 113-366
Range on HMM: 1-268/268
Sequence Identity: 39% (107 aa)

FNLKKVIGRGASGKVYLAEKK-STGERFAIKAIRKDSLPQKKRVSRVRAERNALM-RAKHQFITRLFYAFQSPTKLYFVMEYEAGGDLRHHMDQNTSFSL
| . |..|.|| |||||..||  ... .|.| |.|  . .... .... ||| .   ..| || .|.|.||. .||.|.||| .||.| .|  ..  || 
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

PQIRIYLAELALALKTLHGL-GIVYRDLKPENILLDAEGHIKLADFGLAK-EIN--SESDATSICGTCEYIAPEMLRS-QPQTFAVDWWSFGVIAFQLLC
 |.|.| |.  ||| .||    |.|||||||||||| .||.|..||||.| ..    .  |.|.||| ||.||||..  .. ...||||.||.  . .. 
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

NRLPFASANPQRLFQLIMNNQ---PRIPNNLDSSAQSFLQ-QLLNKEPAKRLGSV---GTDITHHPFF
   || . | ...||.| . |   . .| .. | .....| .||.| | ||||.     ..|  ||.|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 82039.m00042.AA Pkinase 113-366 30 7.3e-89 306.33 Pfam 1-293 (293) Show / Hide 
Range on Protein: 113-366
Range on HMM: 1-293/293
Sequence Identity: 30% (92 aa)

FNLKKVIGRGASGKVYLAEKKSTGERFAIKAIRKDSLPQKKRVSRVR-AERNALMRAKHQFITRLFYAFQSPTKLYFVMEYEAGG----DLRHHMD--QN
. ....||.|..|.||.. .|.||...|.| |.|..   .|.....| .|   . | .| .| ||...|......|.||||  ||    || ...   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

TSF--SLPQIRIYLAELALALKTLHGLGIVYRDLKPENILLDAEGHI----KLADFGLAKE--INSESDATSICGTCEYIAPEMLR-SQPQTFAVDWWSF
..|  |  ... |. ... .|. .|  ||..|||||||||.| .|||    |..||||||   . . | .|..||| .|.||| .| .|. . .||.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVIAFQLLCNRLPFASA------NPQRLFQLIMNNQPRIPNNLD---------------------SSAQSFLQQLLNKEPAKRLGSVGTDITHHPFF
|.| ...|| |.|| ..      ... ....||  ... .   .                     .....|.  .|.| |.||..   ..| .||.|
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT--AEQILQHPWF
Kinase 82039.m00042.AA RSK-Unclassified 113-366 34 2.4e-88 277.55 In-house 1-283 (283) Show / Hide 
Range on Protein: 113-366
Range on HMM: 1-283/283
Sequence Identity: 34% (97 aa)

FNLKKVIGRGASGKVYLAEKKSTGERFAIKAIRKDSLPQKKRVSRVRAERNALMRAKHQFITRLFYAFQSPTKLYFVMEYEAGGDLRHHMD--QNTSFSL
|   . ||.|  ||||| .|| |   .|.|   |. . ..... .|  |.| .   .| || .|...||.  .|| .|||  |||.  |.       |. 
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

PQIRIYLAELALALKTLHGLGIVYRDLKPENILLDAEGHIKLADFGLAKEI----------------------NSESDATSICGTCEYIAPEMLRSQPQT
 ..|.|..|  .||  || ....||||||.||.|. |||..| ||.| ..                          . . | ||| ||.||||.|    |
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHT

FAVDWWSFGVIAFQLLCNRLPFASANPQRLFQLIMNNQPRIP--NNLDSSAQSFLQQLLNKEPAKRLGS-VG--TDITHHPFF
 |||||  |.. . .|    |.   |   .|. |  |. ..|  . .   ... .  ||.. ||||||.  |   ||  ||||
KAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF
Kinase 82039.m00042.AA Delta 113-366 41 6.3e-86 291.78 In-house 1-259 (259) Show / Hide 
Range on Protein: 113-366
Range on HMM: 1-259/259
Sequence Identity: 41% (108 aa)

FNLKKVIGRGASGKVYLAEKKSTGERFAIKAIRKDSLPQKKRVSRVRAERNALMRA-KHQFITRLFYAFQSPTKLYFVMEYEAGGDLRHHMDQNTSFSLP
|...||.|.|. ||| ||| | . . .|||...|| . .   |     ||  |. | .| |...|| .||.  .|.|||||  |||| .|. |   |.. 
FHFHKVLGKGSFGKVMLAELKGKNKYYAIKCLKKDVVLEDDDVECTMVERRVLALAWEHPFLCHLFCTFQTKEHLFFVMEYLNGGDLMYHIQQCHRFDEK

QIRIYLAELALALKTLHGLGIVYRDLKPENILLDAEGHIKLADFGLAK-EINSESDATSICGTCEYIAPEMLRSQPQTFAVDWWSFGVIAFQLLCNRLPF
  | | .|. ..|. ||  ||.||||| .|.||| .||||.||||..| ... |. | . ||| .|||||... |  ...||||||||. . .|    ||
RARFYACEIICGLQFLHKKGIIYRDLKLDNVLLDCDGHIKIADFGMCKENMYGEKKASTFCGTPDYIAPEIIKGQKYNHSVDWWSFGVLMYEMLIGQSPF

ASANPQRLFQLIMNNQPRIPNNLDSSAQSFLQQLLNKEPAKRLGS---VGTDITHHPFF
   . . ||. |.|..|  |  ..  |.. |..|....| ||||.      || .|.||
HGEDEDELFWSICNDRPWYPRWITKEAKDCLKKLFERDPEKRLGVQYCPKGDIRQHCFF
Kinase 82039.m00042.AA RSK 113-366 35 7.6e-86 291.51 In-house 1-271 (271) Show / Hide 
Range on Protein: 113-366
Range on HMM: 1-271/271
Sequence Identity: 35% (97 aa)

FNLKKVIGRGASGKVYLAEKK---STGERFAIKAIRKDSLPQKKRVSRVRAERNALMRAKHQFITRLFYAFQSPTKLYFVMEYEAGGDLRHHMDQNTSFS
..|...||.|. .|||.  |.    |.  .|.| |.|...  | |  .  .||. |    |.|| .|.|.||. .|.| .|.  .||||  ..    .||
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFS

LPQIRIYLAELALALKTLHGLGIVYRDLKPENILLDAE----GHIKLADFGLAKEINSESD-ATSICGTCEYIAPEMLRSQPQTFAVDWWSFGVIAFQLL
   ...|.||.|||.  || .|||.|||||||||.|.|    ||||..|||.||.  .|   . . |.| .|.|||.|. |  . |.|||||||. .  |
EREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEML

CNRLPFASANPQRLFQLIMNNQPRI-------PNNLDSSAQSFLQQLLNKEPAKRLGS---VGTDITHHPFF
  ..||.. . ......| . .  .       ....   |.. | ..|   |..|||.      .|  ||.|
TGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase 82039.m00042.AA MAST 113-259 45 3.2e-66 212.38 In-house 1-147 (334) Show / Hide 
Range on Protein: 113-259
Range on HMM: 1-147/334
Sequence Identity: 45% (67 aa)

FNLKKVIGRGASGKVYLAEKKSTGERFAIKAIRKDSLPQKKRVSRVRAERNALMRAKHQFITRLFYAFQSPTKLYFVMEYEAGGDLRHHMDQNTSFSLPQ
|. .|.|..|| |||||...|.|..|||.| |.|. .  |. |. |..|||.|  .. .|.  .||.||. ..|..||||  |||. ...   ..|  . 
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

IRIYLAELALALKTLHGLGIVYRDLKPENILLDAEGHIKLADFGLAK
 ..|.||..|.|  ||  ||| |||||.|.|.|..|||||.||||.|
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSK
Kinase 82039.m00042.AA MAST 269-366 33 4.4e-24 74.24 In-house 223-334 (334) Show / Hide 
Range on Protein: 269-366
Range on HMM: 223-334/334
Sequence Identity: 33% (38 aa)

SICGTCEYIAPEMLRSQP-QTFAVDWWSFGVIAFQLLCNRLPFASANPQRLFQLIMNNQ---PRIPNN--------LDSSAQSFLQQLLNKEPAKRLGSV
..||| .||||| .  |. .  .||||| |.| ...|.   ||   .|. .|| | |       .|          . . ||   ..||.  | ||||. 
QCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGAN

--GTDITHHPFF
   ...  ||||
NGADEVKQHPFF
Kinase 82039.m00042.AA TyrKc 113-366 20 6.1e-15 18.85 SMART 1-280 (280) Show / Hide 
Range on Protein: 113-366
Range on HMM: 1-280/280
Sequence Identity: 20% (60 aa)

FNLKKVIGRGASGKVYLAEKKSTGERFAIKAIRKDSLPQKKRVSRVRAERNALMRA--KHQFITRLFYAFQSP-------TKLYFVMEYEAGGDLRHHMD
  |.|..|.|| |.||... |   .  |.| ...|.      .   . | . ...   .|. | ||. .  ..         |. |||| ..|||...  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

QNTS-FSLPQIRIYLAELALALKTLHGLGIVYRDLKPENILLDAEGHIKLADFGLAKEINSE------SDATSICG--TCE------YIAPEMLRSQPQT
 .   .....   .    |     ||  ... |||   |.|.......| .||||...| ..      .|  .  .   .         ||| ..    |
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

FAVDWWSFGVIAFQLLCN-RLPFAS-----ANPQRLFQLIMNN-QPRIPNN--------LDSSAQSFLQQLLNKEPAKRLGSVGTDITHHPFF
.. | |||||  . .. .   |         ..|........   ...| |          .   .  .|  . .|..|     ..|  | .|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTF--SEI--HECF
Kinase 82039.m00042.AA Pkinase_Tyr 113-265 23 3.8e-11 38.36 Pfam 1-165 (270) Show / Hide 
Range on Protein: 113-265
Range on HMM: 1-165/270
Sequence Identity: 23% (39 aa)

FNLKKVIGRGASGKVYLAEKK----STGERFAIKAIRKDSLPQKK-RVSRVRAERNALMRA-KHQFITRLFYAFQ-----SPTKLYFVMEYEAGGDLRHH
  . |..|.|| |.||... |    .|.   |.| . |..  ..        .| . ..   .|. | ||  .       .  ..| |||| ..|||...
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN--QIYIVMEYMPHGDLLDY

MDQ----NTSFSLPQIRIYLAELALALKTLHGLGIVYRDLKPENILLDAEGHIKLADFGLAKEINSES
  .    . .......  . .. | ..  |.  ... |||   |.|.. ....| .|||||. | ...
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDD
Kinase 82039.m00042.AA S_TK_X 367-425 29 1e-06 29.41 SMART 1-79 (79) Show / Hide 
Range on Protein: 367-425
Range on HMM: 1-79/79
Sequence Identity: 29% (23 aa)

EDIDWDMVAN--KEYKLDFVPSLE----TPDSVENFDNQLTEQTPQDSYTDD----NLNIN----------VQGFSYVG
 .|||| . |  ||..  |.| .      |  ..|||   ||.|| .. .|.    . . |            ||.|| 
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF