Gene 80599.m00044 (T.vaginalis)

80599.m00044

Species: T.vaginalis
Alias: TvagK0261, 80599.m00044
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
80599.m00044.AA Protein None 801 None Fasta, JSON
80599.m00044.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of 80599.m00044.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 80599.m00044.AA TKL 31-278 25 6e-86 291.84 In-house 1-364 (364) Show / Hide 
Range on Protein: 31-278
Range on HMM: 1-364/364
Sequence Identity: 25% (96 aa)

IGKGGFSEVFSASYTPTK--------QMCAVKKLKFRDLSG-------------------------KNFEALSRELQILSKNAHPYLLGFVGFSIDRP--
||.|||.||. . .  .         .  ||||.| .. .                          .... . .|. ..|.  || .. |.|.... |  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------FIIVTEYLPNGSLFDALRWKDNHKPLTGTQKTLIAMCIASGMAKLHKNR--------IMHRDLKSLNILLDEDLL-------------
            . ||.|| |.|||.. |            |.  .|. ||.||. || ..        | |||||| |||.||..              
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-PRVIDFGLSKFYDEKDE-------------------TLTEVLGTTHWMAPELFENK----------------GYTNKIDVYAYGVLLWEMLTNSIPYA-
 . . |||||.| ... .                   |.  . ||. |||||.....                 |. |.|||..|..|||.||  .||. 
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYD

GKSNTQI--------IYDVVKKGKRPPIP------------IRTPSGLKNLINACWDQNPNSRPTFKEIFQQF
 .....|        .. |..||.|||||              .| ..|.|.  |||..|..||.|.|| ...
YPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 80599.m00044.AA TKL-Unique 27-278 31 1.5e-76 260.58 In-house 1-290 (290) Show / Hide 
Range on Protein: 27-278
Range on HMM: 1-290/290
Sequence Identity: 31% (91 aa)

FVKSIGKGGFSEVFSASYTPTKQMCAVKKLKF-RDLSGKNFEALSRELQILSKNA-HPYLLGFVGFSI----DRP-FIIVTEYLPNGSLFDALR------
|...|| ||...|. . .   .   |.|....  |.| .  . ...|. ...|   || .. ..|...    . | ..||.||.| ||| | |       
FWNKIGEGGYGQVYKGKW--RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

-WKDNHKPLTGTQKTLIAMCIASGMAKLHKNR--IMHRDLKSLNILLDED-----LLPRVIDFGLSKFYD-EKDETLT--------EVLGTTHWMAPELF
    |...|.  |.  .| .||.||  || .   |.||||||.|.|.|..     .  ...||||||| . . ..|..        ...|.. |||||..
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

EN--KGYTNKIDVYAYGVLLWEMLTNSI------PYAGKSNTQII--YDVVKKGKRPPIPIRTPSGLKNLINACWDQNPNSRPTFKEIFQQF
..  . |..|.|||..|. |||..|. |      || | . .|..   .......||||| . |  ...||..||...|  ||.| ||    
RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 80599.m00044.AA MLK 25-278 32 1.5e-72 247.32 In-house 1-291 (291) Show / Hide 
Range on Protein: 25-278
Range on HMM: 1-291/291
Sequence Identity: 32% (96 aa)

FQFVKSIGKGGFSEVFSASYTPTK---QMCAVKKLK---FRDLSG-----KNFEALSRELQILSKNA-HPYLLGFVGFSIDR-P-FIIVTEYLPNGSLFD
.|| . ||.|.| .|... .  .       |||. .   | | |      ..||   |.| |||..  ||.   |.| ...  . | ||.||...|||..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

ALRWKDNHKP-----------LTGTQKTLIAMCIASGMAKLHKNR---IMHRDLKSLNILLDE------DLLPRVIDFGLSKFYDEKDETLTEVLGTTHW
 |. ....              .  ..  .|. .|.||. ||..    | |||||| |||.||      ..  .. |||.|..  ..... .   ||  |
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAW

MAPELF---ENKGYTNKIDVYAYGVLLWEMLTNSIPYA-GKSNTQIIYDVVKKGKRPPIPIRTPSGLKNLINACWDQNPNSRPTFKEIFQQF
|||| .   ..  |. | ||. .||.||||||  .||. . .. .|.. |. .|.|||||.  | ..|.|.. ||.|.|..||.|..| |..
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 80599.m00044.AA S_TKc 25-279 27 3.2e-65 223.9 SMART 1-231 (231) Show / Hide 
Range on Protein: 25-279
Range on HMM: 1-231/231
Sequence Identity: 27% (73 aa)

FQFVKSIGKGGFSEVFSASYTPTKQMCAVKKLKFRDLSGKNFEALSRELQILSKNAHPYLLGFVGFSIDRPFIIVTEYLPN--GSLFDALRWKDNHKP--
..... ||||.|..|. .  . |.. .|.|..|         | . ||.|||.|  ||..  . ..  |  . .|.||...  |.||| .. .  |..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LTGTQKTLIAMCIASGMAKLHKNRIMHRDLKSLNILLDEDLLPRVIDFGLSKFYDEKDETLTEVLGTTHWMAPELFENKGYTN-KIDVYAYGVLLWEML
 ..  .   ..  |..... .|...|.|||||  ||||||     ..||||....       | . || ..||||..   ||.  |.|... |..|.|||
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

TNSIPYAGKSNTQIIYDVVKKGKRPPIPIRTPSGLKNLINACWDQNPNSRPTFKEIFQ--------QFA
.   |.    . | ......           .. .|..|. |.. .|. |||  |..|        .. 
CGYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 80599.m00044.AA Pkinase 25-278 25 1.3e-63 222.49 Pfam 1-293 (293) Show / Hide 
Range on Protein: 25-278
Range on HMM: 1-293/293
Sequence Identity: 25% (75 aa)

FQFVKSIGKGGFSEVFSASYTPTKQMCAVKKLKFRDLSGKNFEALSR--ELQILSKNAHPYLLGFVGFSIDRPFII-VTEYLPNG----SLFDALRWKDN
..... ||.|.|..|. .    | .. |||..| |. . .  ... |  |.||. .  ||. . . ..  |.. |  |.||...|    .||| ..  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST-WR

HKPL--TGTQKTLIAMCIASGMAKLHKNRIMHRDLKSLNILLDEDLLP----RVIDFGLSKFY-DEKDETLTEVLGTTHWMAPELFE-NKGYTNKIDVYA
|...  .  .   ..  |..|.. .|...|.|||||. |||.|..  .    ...||||.|..   ... .| . || ..||||.   ...|. |.|...
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

YGVLLWEMLTNSIPYAGK------SNTQIIYDVVKKGKRPPIPIRTP-------------------SGLKNLINACWDQNPNSRPTFKEIFQQ--F
.|..|.|||.   |. |.      .  |.|. . ..  . ..|   .                   . .| .|. |....|..|||...|.|   |
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 80599.m00044.AA Dicty4 25-280 35 6.6e-63 208.69 In-house 1-277 (277) Show / Hide 
Range on Protein: 25-280
Range on HMM: 1-277/277
Sequence Identity: 35% (98 aa)

FQFVKSIGKGGFSEVFSASYTPTKQMCAVKKL--KFRDLSGKNFEALSRELQILSKNAHPYLLGFVGFSI---DRP--FIIVTEYLPNGSLFDALRW---
 .. . ||||.|.||. ..     .  |||||  .  ... .  ... .|  |..|  || .. | | ..     |  . |||||.| |.|.  |.    
INIEQRIGKGSFGEVYKGTW--RGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPS

---KDNHKPLTGTQK-TLIAMCIASGMAKLHK-N-RIMHRDLKSLNILLDEDLLPRVIDFGLSK----FYDEKDETLTEVLGTTHWMAPELFENKGYTNK
   .   ....   .  ..|  .| ||. ||  | .| |||||| |.| |...   | |||||.      | || . | . ||. |||||   ...|. |
EQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMT-ACGTPCWMAPEVMMHQPYNEK

IDVYAYGVLLWEMLTNSIPYA--GKSNTQIIYDVVKKGKRPPIPIRTPSGLKNLINACWDQNPNSRPTFKEIFQQ--FAA
 ||| .| .|||.||  .||.  ...  |..  |. |. |||||  .|  .| ||. ||| .|..||.|.|| |.    .
ADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase 80599.m00044.AA Dicty5 98-282 43 2.3e-60 206.45 In-house 76-260 (260) Show / Hide 
Range on Protein: 98-282
Range on HMM: 76-260/260
Sequence Identity: 43% (81 aa)

IVTEYLPNGSLFDALRWKDN--HKPLTGTQKTLIAMCIASGMAKLHKNRIMHRDLKSLNILLDEDLLPRVIDFGLSKFYDEKDETLTEVLGTTHWMAPEL
.||||  |||||..|. . .   .|.   |.  .|. || .|  ||   | ||||||.|.|. |..   .|||| | | | . .  |  .||  |||.||
HVTEYCHNGSLFNYLNDQRKTTGQPIAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYH-MTMHVGTQCWMACEL

FENKGYTNKIDVYAYGVLLWEMLTNSIPYAGKSNTQI-IYDVVKKGKRPPIPIRTPSGLKNLINACWDQNPNSRPTFKEIFQQFAANI
|  ..|..| |||..|. ||||.|   ||  . .... |   | || || ||   |.   ||| .|| | |  ||.|||| . |   |
FNGQPYHQKCDVYSFGIVLWEMFTRKEPY--DNINNWNIPVMVMKGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase 80599.m00044.AA LRRK 25-280 25 3.3e-59 203.0 In-house 1-351 (351) Show / Hide 
Range on Protein: 25-280
Range on HMM: 1-351/351
Sequence Identity: 25% (89 aa)

FQFVKSIGKGGFS-EVFSASYT-----------------------PTKQMC---AVKKLKFR---------DLSG-----------------------KN
. . ..||.|||  .|. | .                        ..  ||   |.||...          . ..                       ..
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

FEALSRELQILSKNAHPYLLGFVGFSIDRPFIIVTEYLPNGSLFDALRWKDNHK------PLTGTQKTLIAMCIASGMAKLHKNR--IMHRDLKSLNILL
|  . .|. |.|.  ||...  .||.| .|...|.||.|.|.| . |. | ...       .. . |  ||. ||.||..||...  | |||||| ||||
FREFRHEVWIMSHLNHPNIVSLKGFCI-HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILL

---D---------EDLLPRVIDFGLSK--FYDEKDET-LTEVLGTTHWMAPELFE---NKGYTNKIDVYAYGVLLWEMLTNS-IPYAGKS-N-----TQI
   .         ..    ..|||.|   ... .  . .  ..|.  |||||      .. || |.|.|..|..||| || . .|. . .       . .
WSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHM--GVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQ

IYDVVKKGKRPPIP--IRTPS----GLKNLINACWDQNPNSRPTFKEIFQQFAA
| | ...| ||.||  ...|      ...||. ||...|..||.| .|...   
IEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 80599.m00044.AA HH498 25-278 32 5.1e-58 182.35 In-house 1-284 (284) Show / Hide 
Range on Protein: 25-278
Range on HMM: 1-284/284
Sequence Identity: 32% (92 aa)

FQFVKSIGKGGFSEVFSASYTPTKQMCAVKKLKFRDLSGKNF------EALSRELQILSKNAHPYLLGFVGFSIDRP--FIIVTEYLPNGSLFDAL----
. | ..|| | | .|.   .     . |||  .    . |          . ||  |... .||.   ||. ..| |  | |||.|  |||||  |    
IEFHEKIGSGSFGKVYKGEW--RNKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYACCDDPSQFAIVTQYCDNGSLFSILNTIP

-----------RWKDNHKPLTGTQKTLIAMCIASGMAKLHK---NRIMHRDLKSLNILLDEDLLPRVIDFGLSKFY-DEKDETLTEVLGTTHWMAPELFE
             | |   .    |  |.. .| ||  ||      | |||| | |||..||    | ||| | |  |  |...|   |   ||||| | 
IGGAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFS

-NKGYTNKIDVYAYGVLLWEMLTNSIPYAGKSNTQIIYDVVKKGKRPPIPIR----TPSGLKNLINACWDQNPNSRPTFKEIFQQF
 .  |. |.||. |.  .|||.|  .|..         ..  .  |||||.      |    |||  ||...|..||.| .|    
QCQKYSIKVDVFSYAMCIWEMHTREVPFHHYKPAAAAAEMAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL
Kinase 80599.m00044.AA Pkinase_Tyr 25-278 32 9.5e-58 196.2 Pfam 1-270 (270) Show / Hide 
Range on Protein: 25-278
Range on HMM: 1-270/270
Sequence Identity: 32% (89 aa)

FQFVKSIGKGGFSEVFSASYT----PTKQMCAVKKLKFRDLSGKN--FEALSRELQILSKN-AHPYLLGFVGFSI--DRP--FIIVTEYLPNGSLFDALR
 .| | .|.| | ||. . ..     ||. .|||.||  . . ..   |.. ||..|...   || .. ..|  .  ..|   .||.|| |.|.| | ||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK-EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

WK-DNHKPLTGTQKTLIAMCIASGMAKLHKNRIMHRDLKSLNILLDEDLLPRVIDFGLSKFYDEKDETLTEVLG----TTHWMAPELFENKGYTNKIDVY
 . .. .|||  ..  ... ||.||. |. ... ||||   |.|..|..  .. ||||..   ..|.  . . |       ||||| . .. .| | ||.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDVW

AYGVLLWEMLTNS-IP-YAGKSNTQIIYDVVKKGKRPPIPIRTPSGLKNLINACWDQNPNSRPTFKEIFQQF
..|||.||..|   .| |.| ||....  . ..| | |.|  .|  . .|.  ||...|. ||||.|| .|.
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 80599.m00044.AA TyrKc 25-278 29 2.8e-57 197.51 SMART 1-280 (280) Show / Hide 
Range on Protein: 25-278
Range on HMM: 1-280/280
Sequence Identity: 29% (87 aa)

FQFVKSIGKGGFSEVFSASYTPTKQMCAVKKLKFRDLSGKNFEALSRELQILSKN--AHPYLLGFVGFSID--------RPFIIVTEYLPNGSLFDALRW
 .. | .| | | ||. . ..   ...|||.||         |.. ||..|..|    || .. ..|  ..         |  ||.|| |.|.| | || 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KDNHKPLTGTQKTLIAMCIASGMAKLHKNRIMHRDLKSLNILLDEDLLPRVIDFGLSKFYDEK-------DET------LTEVLGTTHWMAPELFENKGY
. ..  |.  ..  ..  ||.||. ||.... ||||   |.|..|..  .. |||||.. ...       |         .  .    ||||| .  . .
HRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

TNKIDVYAYGVLLWEMLTN-SIPYAG-----KSNTQIIYDVVKKGKRPPIPIR--------TPSGLKNLINACWDQNPNSRPTFKEIFQQF
| | ||...||..||..|.   || |     .||...| . ||.|.|.|.|           |. . ...  ||. .|..||||.|| ..|
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEY-VKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 80599.m00044.AA TK 25-278 18 1.3e-53 177.75 In-house 1-486 (486) Show / Hide 
Range on Protein: 25-278
Range on HMM: 1-486/486
Sequence Identity: 18% (90 aa)

FQFVKSIGKGGFS---EVFSASYTPTK-------------------------QMCAVKKLKFR-DLSGKNFEA--------------LSRELQILS--KN
 ...| .|.| |    ||. . . . .                         . .||| ||   . | . |..              . .|.....  . 
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

AHPYLLGFVG-FSID------------RPFIIVTEYLPNGS----LFDALRWKDNHKPL-----------------------------------------
 || .. ..|  . .            .|..||.|| |.|.    | | || .....                                           
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------TGTQKTLIA-------------------MC--IASGMAKLHKN------RIMHRDLKSLNILLDEDLL-----------PRVIDFGLS--
          . |.| |.                    ||  ||.||. ||..      .. ||||   |.|..|..             .. |||||  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

-------KFYDEKDETLTEVLGTTH-------------------------WMAPELFENKG---------YTNKIDVYAYGVLLWEMLTNS-IPYAG-KS
       . |...| . ..  ||.                          ||||| .. .          .| | ||...|||.||..|.   ||.|  |
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

N--------TQIIYDVVKKG--------------KRPPIPIRTP--------------SGLKNLINACWDQNPNSRPTFKEIFQQF
|         | ... ...|               |.| |   |                .  |.  ||. .|. ||||... .|.
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 80599.m00044.AA DRK 31-280 34 2.4e-50 168.75 In-house 7-258 (258) Show / Hide 
Range on Protein: 31-280
Range on HMM: 7-258/258
Sequence Identity: 34% (89 aa)

IGKGGFSEVFSASYTPTKQMCAVKKLKFRDLS-GKNFEALSRELQILSKNAHPYLLGFVGFSIDRPFI-IVTEYLPNGSLFDALRWKDNHKPLTGTQKTL
||.|.. |||  .   |.   |||.|.       .    . ||  ....  ||    | |     | | |..||.| |||   |   |    .       
IGRGNYGEVFRGTWRGTQ--VAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILH--DESIEMDWPLMKQ

IAMCIASGMAKLHKNR--IMHRDLKSLNILLDEDLLPRVIDFGLSK-FYDEKDETLTE-VLGTTHWMAPELFENKGYTNKIDVYAYGVLLWEMLTNSIPY
... .| ||  ||     |.|||||| | | ||     | |||||  |   |. . .    ||. | |||   | .|| | ||| ... |||..|  .||
MMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWECVTRQDPY

AGKSNTQIIYDVVKKGKRPPIPIRTPSGLKNLINACWDQNPNSRPTFKEIFQQFAA
.|.   |..  | . | |||.|   |     |.| ||. .|  ||.. |. .   |
FGMPTFQVVFSVGRHGMRPPMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase 80599.m00044.AA STE 25-279 19 5.7e-49 169.02 In-house 1-359 (359) Show / Hide 
Range on Protein: 25-279
Range on HMM: 1-359/359
Sequence Identity: 19% (72 aa)

FQFVKSIGKGGFSEVFSA-------SYTPTKQM---------CAVKKLKFRDLS---------------GKNFEALSRELQILSKNA--HPYLLGFVGFS
..... ||||.| .|. |        . .|..          .|.|...... .                .... . .|..|..|    ||.   . |  
WEGIEKIGKGAFGTVYKAMNHKNCNIH-KTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

IDRP--------FIIVTEYLPNGSLFDALR----WKDNHK-------PLTGTQKTLIAMCIASG-MAKLHKNRIMHRDLKSLNILLDEDLLPRVIDFGLS
..            |. ||...||| | ..     .....       ..  .|   |.  |  | .. ||...|.|||.|. ||||        .|||..
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVC

KFYDEK----------------DETLTEVLGTTHWMAPELFEN------KGYTNKIDVYAYGVLLWEMLTNSIPYAGKSNTQIIYDVVKK----------
.  ...                ..  . . ||  |||||  ..      |||. | |..  | ...||.|   |..  .... ..   ..          
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

----GKRPPIPIRTP-------------------SGLKNLINACWDQNPNSRPTFKEIFQ---QFA
    |. ||.| ..                    . .|. || | . .|| ||| ..  .    | 
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI