Gene 93129.m00072 (T.vaginalis)
93129.m00072
Species: T.vaginalis
Alias: 93129.m00072, TvagK0421
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 93129.m00072.AA | Protein | None | 431 | None | Fasta, JSON |
| 93129.m00072.kin_dom | Protein Kinase Domain | None | 251 | None | Fasta, JSON |
Protein domains of 93129.m00072.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| PH | 93129.m00072.AA | PH | 11-108 | 17 | 4.3e-11 | 44.11 | SMART | 1-82 (82) | Show / Hide |
Range on Protein: 11-108 Range on HMM: 1-82/82 Sequence Identity: 17% (17 aa) CTNSGWLRVQSETPNVWNRKYVTVCNKSLIISKDESTKSIEKVIQLTNEASFELLKGSATPRFQVNLGKNQKPIIFSATTTEEVSHWISLLRTVQDNG . .|||...| | .......|..|.. ||. . ..| |.. ... . |.. .. ..|.. . || |.. .. ...| VIKEGWLYKKS--K-RWKKRWFVLFNDCLYYYKDK---KPKGSIPLSDC-TVRE-P-----CFEIHH-DR--TYYFQCESEEEMQEWMQAIQKAIHNN |
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| PH | 93129.m00072.AA | PH | 11-106 | 17 | 2.8e-07 | 28.9 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 11-106 Range on HMM: 1-92/92 Sequence Identity: 17% (17 aa) CTNSGWLRVQSETPNVWNRKYVTVCNKSLIISKDESTKSIEKVIQLTNEASFELLKGS-ATPRFQVNLGKNQKPIIFSATTTEEVSHWISLLRTVQD .. .|||.... | . .....|. |.. ||.. .. ..| | . ... .. . ||. . . ..|.| . || .|.. .. .. VIKEGWLHKKG-KRKSWKKRWFVLFNNCLYYYKDDK-YRPKGSIPLSDC-QVTKVPDNKRPHCFQIRT-DR-RTYYFQAESEEEMNDWMQAIQSACR |
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| Kinase | 93129.m00072.AA | AGC | 116-366 | 30 | 3.9e-154 | 401.85 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 116-366 Range on HMM: 1-395/395 Sequence Identity: 30% (122 aa) FQIISVIGRGYYGKVMLVRRI------DTDQLYAIKSIRKSR--------LAEMDSCS--------VLTEKNIMMKIH----------HPFIVN-LCFAF |... |||.| .|||.|||. ||...||.| ..|.. |. | |.||..|.. |||||. | ..| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF QTDTK--VYLGLEYAP---------GG-ELFYYME---SNGTIPVDDARLYVAE-------IGLALAHLHK-YGIIYRD-LKPENILFDADGHIKLTDFG |.... .|. .||.| || |||... .|. . . || | || | ||| .||. |||.|| |||||||.|.|||||||||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG LSKELGVDG---------------------------------------------------TAKTFCG--TPDYLAPEVIPQEKYTTKIDEWA--LGVLTY |.||. || ...|||| ||.|.|||.. |. | |. ||.| | LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY EMILGRTPFCNDN----------KNEMFQEIV------TLDPYFP----------EGMDPRIINFIMRLLTKDPKERPT----------FDDVKSDPFF ||. |..||..|| ..|||| | . .. || . ..| ..| .||.|||..|.. ....|. |.| EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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| Kinase | 93129.m00072.AA | Akt | 116-366 | 44 | 4.8e-114 | 365.98 | In-house | 1-264 (264) | Show / Hide |
Range on Protein: 116-366 Range on HMM: 1-264/264 Sequence Identity: 44% (118 aa) FQIISVIGRGYYGKVMLVRRIDTDQLY-AIKSIRKSRLAEMDSC-SVLTEKNIMMKIHHPFIVNLCFAFQTDTKVYLGLEYAPGGELFYYMESNGTIPVD |... |.|.| .|||.||. ||...| |.|...|... ... ..||.|| .. ||||||| ..||| .| |. ..|..||||||.. .... | FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED DARLYVAEIGLALAHLHKYGIIYRD-LKPENILFDADGHIKLTDFGLSKEL-GVD-GTAKTFCGTPDYLAPEVIPQEKYTTKIDEWA-LGVLTYEMILGR || |.||| ||. |||. .||||| ||||||| |.||||.||||||.|| | ..||||||| |||||.. . .| . | |. ||...|||. || RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR TPFCNDNKNEMFQEIVTLDPYFP--EGMDPRIINFIMRLLTKDPKERP-----TFDDVKSDPFF || |... .||. | . . || . .| ..| .||.||||.|. . ...|..|.| PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF |
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| Kinase | 93129.m00072.AA | S_TKc | 116-366 | 37 | 3e-105 | 356.9 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 116-366 Range on HMM: 1-231/231 Sequence Identity: 37% (99 aa) FQIISVIGRGYYGKVMLVRRIDTDQLYAIKSIRKSRLAEMDSCSVLTEKNIMMKIHHPFIVNLCFAFQTDTKVYLGLEYAPG--GELFYYMESNGT---- ..|. .||.| .|||...| ..|....||| |. .... | .|..| |||.||.| .||. ...|. .||..| |.|| |....|. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR --IPVDDARLYVAEIGLALAHLHKYGIIYRDLKPENILFDADGHIKLTDFGLSKELGVDGTAKTFCGTPDYLAPEVIPQEKYTT-KIDEWALGVLTYEMI .| .|| |...| .||...|. |||.|||||||||.| |||..||||...| .||||||.|.||||. .|.. |.| |..|.. |||. FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML LGRTPFCNDNKNEMFQEIVTLDPYFPEGMDPRIINFIMRLLTKDPKERPTFDDVKS-------DPFF |..||. . ..||. |. .| ..||...|.|||..||| .. .|.| CGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 93129.m00072.AA | SGK | 116-366 | 39 | 1.7e-104 | 323.68 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 116-366 Range on HMM: 1-283/283 Sequence Identity: 39% (112 aa) FQIISVIGRGYYGKVMLVRRIDT------------------DQLYAIKSIRK-SRL-------AEMDSCSVLTEK-NIMMKIHHPFIVNLCFAFQTDTKV |....||| | .|||..|.. |. |..||.| ..| ... . ...|. .|. .. ||||||| .||||..| FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL YLGLEYAPGGELFYYMESNGTIPVDDARLYVAEIGLALAHLHKYGIIYRDLKPENILFDADGHIKLTDFGLSK-ELGVDGTAKTFCGTPDYLAPEVIPQE |. ..|. |||.||.. . | | || |.||| .|| .||. |||||||||||| |..||..||||||.| . | .|||||| ||||||. . YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ KYTTKIDEWALGVLTYEMILGRTPFCNDNKNEMFQEIVTLDPYFPEGMDPRIINFIMRLLTKDPKER----PTFDDVKSDPFF . | | || . |||. | || . ||..|.. | . .| .| . | ||.||||.| | ..|. ||| PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF |
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| Kinase | 93129.m00072.AA | AktR | 116-366 | 41 | 2.3e-98 | 333.1 | In-house | 1-268 (268) | Show / Hide |
Range on Protein: 116-366 Range on HMM: 1-268/268 Sequence Identity: 41% (112 aa) FQIISVIGRGYYGKVMLVRRI-DTDQLYAIKSIRKSRLAEMDSCS-VLTEKNIMM-KIHHPFIVNLCFAFQTDTKVYLGLEYAPGGELFYYMESNGTIPV |... ..|.| .|||.||.. |....||.|.|.|. . | . ..||.||| .. |||||.| ..|||..| .. .|| ||||||.. ..... FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE DDARLYVAEIGLALAHLHKY-GIIYRDLKPENILFDADGHIKLTDFGLSK-ELG--VDGTAKTFCGTPDYLAPEVIPQ-EKYTTKIDEWALGVLTYEMIL ..|| | |.| ||| .||. |||||||||||| | |||.|.||||||| . | .|..||||| |.|||.| . . .. .| ||.|.. |||. EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT GRTPFCNDNKNEMFQEIVTLD-PYFPEGMDP--RIINFIM-RLLTKDPKERPT-----FDDVKSDPFF | .|| ..|.|.||| | . . .||. ... ..| .|| |.|..|.. ....|| |.| GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF |
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| Kinase | 93129.m00072.AA | RSK | 119-366 | 39 | 5.8e-97 | 328.43 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 119-366 Range on HMM: 1-278/278 Sequence Identity: 39% (109 aa) ISVIGRGYYGKVMLVRRI---DTDQLYAIKSIRKSRLAEM--DSCSVLTEKNIMMKIH-HPFIVNLCFAFQTDTKVYLGLEYAPGGELFYYMESNGT--- ..| |.| |||| |.|.. ||.|.|| | ..|. .. | ..|| ||.. . |||||.| ||||..|.|| .|| .|||||. . .. LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC IPVDDARLYVAEIGLALAHLHKYGIIYRDLKPENILFDA---DGHIKLTDFGLSKELGVD--GTAKTFCGTPDYLAPEVIP---QEK-YTTKIDEWALGV . |.|. | ||| ||. |||. |||.|||||||||.| .|||||||||..|.. | . ..|||.| .|.|||.. |.. .. | | ||| FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV LTYEMILGRTPFCN---DNKNEMFQEIVTLD--PYFP--EGMDPRIINFIMRLLTKDPKERPT-----FDDVKSDPFF | ||| |..|| . .|..| .. | . . . .| . . . ..| ..|..||. |.. ...|..|.| LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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| Kinase | 93129.m00072.AA | PKC | 116-366 | 38 | 1.1e-90 | 294.1 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 116-366 Range on HMM: 1-262/262 Sequence Identity: 38% (102 aa) FQIISVIGRGYYGKVMLVRRIDTDQLYAIKSIRKSRLAEMDSC-SVLTEKNIM-MKIHHPFIVNLCFAFQTDTKVYLGLEYAPGGELFYYMESNGTIPVD |. . |.|.| .|||||..| .||..|||| ..| . | ...||| .. ||| ..| ||| . . .|| || | . . . . .. FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE DARLYVAEIGLALAHLHKYGIIYRDLKPENILFDADGHIKLTDFGLSKE-LGVDGTAKTFCGTPDYLAPEVIPQEKYTTKIDEWALGVLTYEMILGRTPF || | ||| .|| ||. |||||||| .|.| |..||||..|||..|| . . |..||||||||.|||.. ..|. .| ||.||| ||| .|. || HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF CNDNKNEMFQEIVTLDPYFPEGMDPRIINFIMRLLTKDPKERPTF--------DDVKSDPFF .. |.|| | . .|..| . .. . . ..||.|..| .|... ||| HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF |
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| Kinase | 93129.m00072.AA | CAMK | 121-366 | 22 | 1.4e-87 | 282.21 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 121-366
Range on HMM: 1-425/425
Sequence Identity: 22% (96 aa)
VIGRGYYGKVMLVRRIDTD------------QLYAIKSIRKSRLA--------------------------EMDSCSVLTEKNIMMK-------IHHPFI
..||| .||| |.... | | .||| | |..| . | .|. | .||.| ..|| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
VNLCFAFQ------------TDTK--------VYLGL---EYAPGGEL----FYYMESN---------------GTIPVDDARLYVAEIGLALAHLHKYG
..| ... | .| .|. . ||..|||| | | .. | .. ..|| |. | |....|. .
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN
IIYRDLKPENILFDAD-----------------GHIKLTDFGLSKELGV------------------------DGTAKTFCGTPDYLA-PEVIPQ-----
|. |||||||||.| . . ||..|||..... . ||||||| | | |||. .
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN
---------EKYTTKIDEWALGVLTYEMILGRTPFCND-------------NKNEMFQEIVTLDPYFPEGMDPR------------------------II
. |. |.| |..||..| | |. || | | .|.|. | . . .||. . . .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK
NFIMRLLTKDPKERPTFDDVKSDPFF
..| ..|..||..|.| ......|..
DLIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | 93129.m00072.AA | Pkinase | 116-366 | 31 | 2.1e-87 | 301.45 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 116-366 Range on HMM: 1-293/293 Sequence Identity: 31% (94 aa) FQIISVIGRGYYGKVMLVRRIDTDQLYAIKSIRKSRLAEMDSCSVLT--EKNIMMKIHHPFIVNLCFAFQTDTKVYLGLEYAPGG----ELFYYME--SN ..|...||.| .|.| . ....| ...|.| |.|.. . . . | || ...||.|| | .|......|. .||..|| .|| |.. .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH GTI--PVDDARLYVAEIGLALAHLHKYGIIYRDLKPENILFDADGHI----KLTDFGLSKE--LGVDGTAKTFCGTPDYLAPEVIP-QEKYTTKIDEWAL |.. . .... |. .| .|...|. |||.|||||||||.| .||| |..||||.| . .. ..||||||.|.||||| ...|..|.| |.. GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GVLTYEMILGRTPFCND------NKNEMFQEIVTLDPYFPEGMD---------------------PRIINFIMRLLTKDPKERPTFDDVKSDPFF |.. |||..||.||... ....|...| .. |.. . . . || ..|.||||.|||..... .|.| GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | 93129.m00072.AA | PKA | 116-366 | 40 | 2.6e-87 | 296.38 | In-house | 1-263 (263) | Show / Hide |
Range on Protein: 116-366 Range on HMM: 1-263/263 Sequence Identity: 40% (106 aa) FQIISVIGRGYYGKVMLVRRIDTDQLYAIKSIRKSRLAEMDSCS-VLTEKNIMMKIHHPFIVN-LCFAFQTDTKVYLGLEYAPGGELFYYMESNGTIPVD |.|| ..|.| .|.|||.| .. . ||.| ..|.. . |..||||.. |.|||||. . . ||.|.. |. .||.||||.|.|. .| . . FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP DARLYVA-EIGLALAHLHKYGIIYRDLKPENILFDADGHIKLTDFGLSKELGVDGTAKTFCGTPDYLAPEVIPQE-KYTTKIDEWALGVLTYEMILGRTP .|..|.| .| ||| ||. |||||||||||| | .||||.|||| .|. ||. .| ||||.|||||.| . . .| ||||.| ||| | .| HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKK--VDDRTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPP FCND--NKNEMFQEIVTLDPYFPEGMDPRI---INFIMRLLTKDPKERP---TF--DDVKSDPFF | .. ....... |. . ||. .|.. .| .||..|...| . .|.| ..| FYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF |
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| Kinase | 93129.m00072.AA | p70 | 116-366 | 35 | 2.3e-81 | 276.63 | In-house | 1-299 (299) | Show / Hide |
Range on Protein: 116-366 Range on HMM: 1-299/299 Sequence Identity: 35% (106 aa) FQIISVIGRGYYGKVMLVRRID---TDQLYAIKSIRKSRL--AEMDSCSVL-------------------------TEKNIMMKIHHPFIVNLCFAFQTD |. . |.|.| ||||..|| | ..|| | .|| . | . | || . ||||. | .||||. FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN TKVYLGLEYAPGGELFYYMESNGTIPVDDARLYVAEIGLALAHLHKYGIIYRDLKPENILFDADGHIKLTDFGLSKELGVDGTA-----------KTFCG | || ||| .|||||. | |. . | |. | .|| .|| |||. |||||||||||.. .. ||..||||||.|| ||. |||| GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG TPDYLAPEVIPQEKYTTKIDEWALGVLTYEMILGRTPFCNDNKNEMFQEIVTLD--PYFPEGMDPRIINFIMRLLTKDPKERPT-----FDDVKSDPFF |. | |||.. . .| |.||.| | | | || .|. . | . | . | .|| ..|..| . |....||| TIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF |
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| Kinase | 93129.m00072.AA | Ciliate-E2 | 116-366 | 24 | 3.6e-80 | 272.64 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 116-366 Range on HMM: 1-365/365 Sequence Identity: 24% (91 aa) FQIISVIGRGYYGKVMLVRRIDTD-----------------------QLYAIKSIRKSRLAEMDS-CSVL----------TEKNIMMKIHHPFIVNLCFA . .| .||.| .|.| ..... .. ..||.|...|. . .. . ... ||||. .. ||.|... . YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC FQ--TDTKVYLGLEYAPGGELFYYMESNGTIP-----------VDDARLYVAEIGL---------------ALAHLHKYG-IIYRDLKPENILFDADGHI || .|...|| .||. ||.||.|...| . .. . ..| || .||. . ||.||.||||||| | FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I KLTDFGLSKELGVD--------------------------------GTAKTFCGTPDYLAPEVIPQEK---------YTTKIDEWALGVLTYEMILGRTP |..||||||.. | ...|.|||| |.|||.. .| |..|.| |.|||. |||. |..| KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP FCNDNKNEMFQEIVTLDPYFP------------------EGMDPRIINFIMR----LLTKDPKERPT-FDDVKSDPFF | .|.| . || . .. ...| . .| |||..|.| ..... |.| F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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| Kinase | 93129.m00072.AA | TyrKc | 116-364 | 21 | 1.3e-16 | 46.09 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 116-364 Range on HMM: 1-280/280 Sequence Identity: 21% (62 aa) FQIISVIGRGYYGKVMLVRRIDTDQLYAIKSIRKSRLAEMDSCSVLTEKNIMMKI--HHPFIVNLCFAFQTD-------TKVYLGLEYAPGGELFYYMES . . ..|.| .|.|.. . . . |.|..... . | .||.|. ||| ||.| . .. ... .||.|.| | | . ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK NGT-IPVDDARLYVAEIGLALAHLHKYGIIYRDLKPENILFDADGHIKLTDFGLSKELGVD------GTAKTFCG--TPD------YLAPEVIPQEKYTT .. ....| . | ..||. ..| ||| |.| ......| .|||||.... | . .. . . .|||.| |.|| HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT KIDEWALGVLTYEMI-LGRTPFCN-----DNKNEMFQEIVTL-DPYFPEG--------MDPRIINFIMRLLTKDPKERPTFDDVKSDP | | |. ||. .|. .| .| . . |... . . . |. . . . . . . ||..|||| ..... KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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| Kinase | 93129.m00072.AA | S_TK_X | 367-427 | 31 | 1.2e-13 | 52.58 | SMART | 1-79 (79) | Show / Hide |
Range on Protein: 367-427 Range on HMM: 1-79/79 Sequence Identity: 31% (25 aa) EGVDWDAVYN--REHSPSYIPEIK----DRMCTNNFDPEFTTELAADSFVSPGIHAFGN------------IAGFSYVE |.|||..|| .| | ..|.|| . .|.||||||| | . .. ..|.. . . .||.|| RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF |
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| Kinase | 93129.m00072.AA | Pkinase_Tyr | 116-363 | 24 | 1e-10 | 36.89 | Pfam | 1-269 (270) | Show / Hide |
Range on Protein: 116-363 Range on HMM: 1-269/270 Sequence Identity: 24% (67 aa) FQIISVIGRGYYGKVMLVRRI----DTDQLYAIKSIRKSRLAEMD--SCSVLTEKNIMMKI-HHPFIVNLCFAFQ-TDTK--VYLGLEYAPGGELFYYME ... ..|.| .|.|.. . .|.. |.|.. | . . . . . | .||... ||| ||.| . . .|. .||.|.| | | ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR S----NGTIPVDDARLYVAEIGLALAHLHKYGIIYRDLKPENILFDADGHIKLTDFGLSKEL-------GVDGTAKTFCGTPDYLAPEVIPQEKYTTKID . .. ... | . ..| ....|. ..| ||| |.| . ....| .||||.. . . | .| . .|||.| |.||| | KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LP--IKWMAPECINYGKFTTKSD EWALGVLTYEMIL-GRTP-FCNDNKNEMFQEIV--TLDPYFPEGMDPRIINFIMRLLTKDPKERPTFDDVKSD |. ||| .|.. |..| . . .|... | ||. . | . ... .||..|||| .. .. VWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQ |
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| Kinase | 93129.m00072.AA | Pkinase_C | 386-429 | 37 | 1.5e-07 | 29.86 | Pfam | 1-46 (46) | Show / Hide |
Range on Protein: 386-429 Range on HMM: 1-46/46 Sequence Identity: 37% (18 aa) EIKDRMCTNNFDPEFTTELAADSF----VSPGIHAFGNIAGFSYVEPN ..|.. .| ||||||| | . |.. |.| .. . ||.|| |. QVKSPTDTSNFDPEFTDEPPMDTPPDWRMSSGDQE--PFRGFTYVNPD |
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