Gene 90492.m00270 (T.vaginalis)

90492.m00270

Species: T.vaginalis
Alias: 90492.m00270, TvagK0312
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
90492.m00270.AA Protein None 779 None Fasta, JSON
90492.m00270.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of 90492.m00270.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 90492.m00270.AA TKL 47-291 23 2.4e-71 243.31 In-house 1-364 (364) Show / Hide 
Range on Protein: 47-291
Range on HMM: 1-364/364
Sequence Identity: 23% (89 aa)

IGSGTFGEVWRAKGNDEK--------GTAAIKILFNEELSKAEL-------------------------KHFLMEVEILVRCQSRFVIPFVGFTNTYP--
||||.||||...| . .          . |.|..  .. .. ..                         ...  |. .. |..   ...|.|. .  |  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YAVATRLATNGN-LADFIGIMRNQGKYPSTIFQRIAIGIAVGMQYLHNLG--------IIHRDLKPSNILLNKNYL------------
            ..  . .. .|. | ...             . |.|..|| ||.|||. .        |||||||..|||...|.             
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--PLICDFGVSR-NTLSNVMTK--------------------CTGTPQWMAPEIVAGS----------------EYSLSADIFSYGMILYEIATLTRPFE
  . ||||| || .. |. |..                    . |||.|||||.  |.                ||| ..|..|.|..|.||.|  ||..
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY

GIPVSTIL---------REVL-KGTRPTLP------------TNIHPGMRELIIRCWMSDPRLRPSFKEIINLL
..| ....           |  || ||..|            ... |.|..|. .|| .||. ||||.||.  |
DYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 90492.m00270.AA MLK 41-291 27 2.4e-60 206.79 In-house 1-291 (291) Show / Hide 
Range on Protein: 41-291
Range on HMM: 1-291/291
Sequence Identity: 27% (80 aa)

FQLEKKIGSGTFGEVWRAKGNDEK---GTAAIKILF-NEELSKAE----LKHFLMEVEILVRCQSRF----VIPFVGFTNTY-P-YAVATRLATNGNLAD
.|....||||.||.||...   .     . |.|. . . . .|..     ..| ||...| . . .     .|.|.|  . . . ... .  . .| |..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

FIGIMRNQGK-----------YPSTIFQRIAIGIAVGMQYLHNLG---IIHRDLKPSNILLNK-----NYLPL-ICDFGVSRNTLSNV---MTKCTGTPQ
..   |...            |.   . ..|  .| ||.|||..    |||||||..|||.       ... | |||||.||  ...    |..  ||. 
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRD-WHQMCTNMMSNAGTYA

WMAPEIV---AGSEYSLSADIFSYGMILYEIATLTRPFE-GIP-VSTILREVLKGTRPTLPTNIHPGMRELIIRCWMSDPRLRPSFKEIINLL
|||||.     .. || ..|..|.|..|.|. |   |.. ..     .   ...|.||..| .. ... .|. .|| .||. ||||..|.  |
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 90492.m00270.AA LRRK 111-293 32 7.6e-58 198.49 In-house 129-351 (351) Show / Hide 
Range on Protein: 111-293
Range on HMM: 129-351/351
Sequence Identity: 32% (72 aa)

PYAVATRLATNGNLADFIGIMRNQG------KYPSTIFQRIAIGIAVGMQYLHNLG--IIHRDLKPSNILL---N---------KNYLPLICDFGVSR--
|.. .. .|..|.| .|.   .. |      . . .....||. || ||.|||.    |||||||. ||||   .          ..   |.||| ||  
PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMF

NTLSN-VMTKCTGTPQWMAPEIVAG---SEYSLSADIFSYGMILYEIATLT-RPFEGIP-------VSTILREVLKGTRPTLPTN-IHP-----GMRELI
 .. . |  .|.|.|.||||||. .   .||.  .|..|.||||.|. |.. .||....        ..|  ....| |||.| .  .|      . .||
QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDLI

IRCWMSDPRLRPSFKEIINLLCD
  ||  ||. ||.| .|.  | .
QHCWQHDPKKRPHFSQIVKRLSQ
Kinase 90492.m00270.AA Pkinase 41-291 24 1.2e-52 186.05 Pfam 1-293 (293) Show / Hide 
Range on Protein: 41-291
Range on HMM: 1-293/293
Sequence Identity: 24% (72 aa)

FQLEKKIGSGTFGEVWRAKGNDEKGTAAIKILFNEELSKAELKHFLM--EVEILVRCQSRFVIPFVGFT--NTYPYAVATRLATNG----NLADFIGIMR
.....|||||.||.|....  ..  . |.||.  .. .. .... .   |..|. |... ... . ..   ....| . . .. .|     |.|.|   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIY-MVMEYCEGGLYVMDLFDYIST-W

NQGKY--PSTIFQRIAIGIAVGMQYLHNLGIIHRDLKPSNILLNKNYLP----LICDFGVSR---NTLSNVMTKCTGTPQWMAPEIVA-GSEYSLSADIF
..|..  .    ....  |. |..|.|. |||||||||.|||...|. .     |||||...   .  .  ||  .||| .||||..  |..|. ..|..
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SYGMILYEIATLTRPFEGI----PVSTILREVLKGTRPTLPTNIH-----------------------PGMRELIIRCWMSDPRLRPSFKEIINL--L
|.| |||| ..   || |     .  . .  . .  .| |. ..                        . ....| .|.  ||  ||....| .   .
SCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 90492.m00270.AA S_TKc 41-298 26 1.5e-52 181.79 SMART 1-231 (231) Show / Hide 
Range on Protein: 41-298
Range on HMM: 1-231/231
Sequence Identity: 26% (70 aa)

FQLEKKIGSGTFGEVWRAKGNDEKGTAAIKILFNEELSKAELKHFLMEVEILVRCQSRFVIPFVGFTNTYPYAVATRLATN--GNLADFIGIMRNQGK--
... .|||.|.||.|.... .. .   ||||.          .|.. |..|| . .  ... . ..  .  . . . .. .  |.| |.|  .. .|.  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-YPSTIFQRIAIGIAVGMQYLHNLGIIHRDLKPSNILLNKNYLPLICDFGVSRNTLSNVMTKCTGTPQWMAPEIVAGSEYSL-SADIFSYGMILYEIATL
 .|    ....  |. ...|.|..|||||||||.||||..     |||||..|       | . ||| .||||..    |.  ..|. | | |||| .. 
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCG

TRPFEGIPVSTILREVLKGTRPTLPTNIHPGMRELIIRCWMSDPRLRPSFKEIIN--LLCDFRAVF
  ||.   . .... ..            | ....| .|.  ||. ||.  |. .  ..      |
YPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 90492.m00270.AA TKL-Unique 144-291 35 8.4e-50 171.77 In-house 114-290 (290) Show / Hide 
Range on Protein: 144-291
Range on HMM: 114-290/290
Sequence Identity: 35% (62 aa)

RIAIGIAVGMQYLHNLG--IIHRDLKPSNILLNKN-----YLPLICDFGVSRNTLSNVMTKCT-----------GTPQWMAPEIVAG--SEYSLSADIFS
..|| || || |||...  |||||||.||.|.. |     .   ||||| |..  ..  .. .           |...|||||.  .  . || ..|..|
KMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYS

YGMILYEIATLTR------PFEGIPVSTIL---REVLKGTRPTLPTNIHPGMRELIIRCWMSDPRLRPSFKEIINLL
.|..|.|||| ..      |..|.    ..   ...... ||..|... .  |.|| .|| .||  |||| |||. |
FGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 90492.m00270.AA Dicty4-Unclassified 139-291 41 2e-49 167.39 In-house 108-263 (263) Show / Hide 
Range on Protein: 139-291
Range on HMM: 108-263/263
Sequence Identity: 41% (64 aa)

STIFQRIAIGIAVGMQYLHNLGIIHRDLKPSNILLNKNYLPLICDFGVSRNTLSNV-MTKCTGTPQWMAPEIVAGSEYSLSADIFSYGMILYEIATLTRP
.|.  ..|. || |||.||   .||||.| ||||. |..   | |||.|| .  |  ||   ||| | .||.  .  |   .|..||.|.||| ||   |
DTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMMLYELATGDEP

FEGIP-VSTILREVL-KGTRPTLPTNIHPGMRELIIRCWMSDPRLRPSFKEIINLL
. .|. .  . | |  |. || .| |. . .. ||  ||  ||. ||.. .||. |
YQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase 90492.m00270.AA TK 41-291 14 3.9e-48 159.02 In-house 1-486 (486) Show / Hide 
Range on Protein: 41-291
Range on HMM: 1-486/486
Sequence Identity: 14% (71 aa)

FQLEKKIGSGTFG---EVWRA------KGNDEKG-------------------TAAIKILFNE-ELSKAELKH-----------FLMEVEILVRCQ----
 .|.||.|.| ||   ||...      ..| ...                   . |.|.|  . . |..| .            ||.|.|..   .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-SRFVIPFVG-FTNT------------YPYAVATRLATNGN----LADFIGIMRNQGKYPSTIFQR----------------------------------
    .. ..|  |               |. . . .. .|.    | |.    |. .. ..   ..                                  
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

--------------------------------------IAIGIAVGMQYLHNL------GIIHRDLKPSNILLNKNYL-----------PLICDFG----
                                      ..  || ||.||| .      ...||||   |.|...|.              |.|||    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----VSRNTLSN-VMTKCTGTPQ---------------------------WMAPEIVAGSE---------YSLSADIFSYGMILYEIATLT-RPFEG-IP
     .|   |.   .. ..                              ||||| ... .         ..   |..|.|  ..|| |.   |. | ..
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

V---------STILREVLKG--------------TRPTLPTNIH--------------PGMRELIIRCWMSDPRLRPSFKEIINLL
            ... . .|               |.  | . .              . . .|. .||  ||. ||.|... . |
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 90492.m00270.AA Dicty5 116-295 37 5.6e-47 159.72 In-house 78-260 (260) Show / Hide 
Range on Protein: 116-295
Range on HMM: 78-260/260
Sequence Identity: 37% (69 aa)

TRLATNGNLADFIGIMRNQGKYPSTIFQR--IAIGIAVGMQYLHNLGIIHRDLKPSNILLNKNYLPLICDFGVSR-NTLSNVMTKCTGTPQWMAPEIVAG
| .  || | .     |.    |  .||.  .||.|| .|..||  .|||||||  |.|...|.   | |||.||   .   ||   ||. |||.|.  |
TEYCHNGSLFNYLNDQRKTTGQPIAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNG

SEYSLSADIFSYGMILYEIATLTRPFEGIPVSTILREVLKGTRPTLPTNIHPGMRELIIRCWMSDPRLRPSFKEIINLLCDFR
  |   .|..|.| .|.|. |   |.. |    |   | || |||.|  .      ||  ||   |..|||||||.  .    
QPYHQKCDVYSFGIVLWEMFTRKEPYDNINNWNIPVMVMKGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase 90492.m00270.AA Dicty4 136-293 37 2.5e-46 152.58 In-house 105-277 (277) Show / Hide 
Range on Protein: 136-293
Range on HMM: 105-277/277
Sequence Identity: 37% (66 aa)

KYPSTIFQR---IAIGIAVGMQYLHN--LGIIHRDLKPSNILLNKNYLPLICDFGVSR-----NTLSN-VMTKCTGTPQWMAPEIVAGSEYSLSADIFSY
| ... . |   .|. .| ||..||.    |||||||..|.|  ||.   .|||| |.      ...   || | ||| |||||. .. .|  .|| .|.
KLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTAC-GTPCWMAPEVMMHQPYNEKADVYSF

GMILYEIATLTRPFE--GIPVSTILREVLK-GTRPTLPTNIHPGMRELIIRCWMSDPRLRPSFKEIINL--LCD
|..|.||.|   |.   ..|   . | |   . || .| .  |  ..|| .||  ||  ||||.|||.   |  
GIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase 90492.m00270.AA TyrKc 41-291 24 2.1e-44 154.75 SMART 1-280 (280) Show / Hide 
Range on Protein: 41-291
Range on HMM: 1-280/280
Sequence Identity: 24% (71 aa)

FQLEKKIGSGTFGEVWRAKGNDEKGTAAIKILFNEELSKAELKHFLMEVEILVRC--QSRFVIPFVGFTNT--------YPYAVATRLATNGNLADFIGI
 .|.||.|.| ||||.... .    . |.| | ..      .. |. | .|. .   .   .. ..|   .         |. . . .. .|.| |..  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

MRNQGKYPSTIFQRIAIGIAVGMQYLHNLGIIHRDLKPSNILLNKNYLPLICDFGVSRNTLSN-------VMTKCT---GTPQ-----WMAPEIVAGSEY
 |..   .   .  ... || ||.|||  ..|||||   |.|...|.   |.||| ||.  .         . . .   |.       |||||    ...
HRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

SLSADIFSYGMILYEIATL-TRPFEG-----IPVSTILREVLKGTRPTLPTN--------IHPGMRELIIRCWMSDPRLRPSFKEIINLL
.   |..|.|  ..|| |.   | .|     .. . ... | .| |.  | |         .. | ... .||. ||  ||.|.||. ..
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 90492.m00270.AA Ciliate-E2-Unclassified 41-289 19 2.3e-42 144.75 In-house 1-348 (352) Show / Hide 
Range on Protein: 41-289
Range on HMM: 1-348/352
Sequence Identity: 19% (68 aa)

FQLEKKIGSGTFGEVWRAKGNDEKGTAAIKILFNEELSKAELKHF----------LMEVE-------------ILVRCQSRFVIPFV-GFTNTYPYAVAT
. . |.||.| ||.|.... ...|  .|.|..      |  .. .          ... .             ||. ... |.. ..  |...      .
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

RLATNGNLADFIGI--------------MRNQGKYPSTIFQ-----RIAIGIAVGMQYLHNLG-IIHRDLKPSNILLNKNY---LPLICDFGVSR-----
 .. .|.| ..| .              |... . .    .     ...  | .| .|||  . |||||.||.|||...|     . |.||| |.     
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

------------NTLSNVMTKCTGTPQWM----APEIVAGSEYSLS----ADIFSYGMILYEIATLTRPFEGIPVST----------------ILREVLK
            .. .. |. ..|||. |    |||.  | .|. |    .||.| |.||||. . ..||..                     .... ..
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

G---TRPTLP----TNIHPGMRELII----RCWMSDPRLRPSFKEIIN
.    ..  .     ...|   ..|     ..   .|  |..|..|.|
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILN
Kinase 90492.m00270.AA Pkinase_Tyr 41-291 26 1.4e-38 131.27 Pfam 1-270 (270) Show / Hide 
Range on Protein: 41-291
Range on HMM: 1-270/270
Sequence Identity: 26% (71 aa)

FQLEKKIGSGTFGEVWRAKGN----DEKGTAAIKILFNEELSKAE--LKHFLMEVEILVRC-QSRFVIPFVGFTN--TYP--YAVATRLATNGNLADFIG
 .. ||.|.| ||||.... .    ..| . |.|.| .|  .. .  .. |. |..|.    .   .. ..|       |  . . . .. .|.| |.  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

IM-RNQGKYPSTIFQRIAIGIAVGMQYLHNLGIIHRDLKPSNILLNKNYLPLICDFGVSRNT-LSNVM-TKCTGTP---QWMAPEIVAGSEYSLSADIFS
    .... .      ... || ||.||.. ..|||||   |.|...|    ||||| .|         .| .|..    |||||  . ....   |. |
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

YGMILYEIATLT-RP-FEGIPVSTILREV-LKGTRPTLPTNIHPGMRELIIRCWMSDPRLRPSFKEIINLL
.|  ..|| |.   | ..|.. . ... .  .| |   | | .. . .|. .||. ||  ||.|.||.. |
FGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 90492.m00270.AA STE 140-286 24 4.3e-35 121.4 In-house 151-350 (359) Show / Hide 
Range on Protein: 140-286
Range on HMM: 151-350/359
Sequence Identity: 24% (50 aa)

TIFQRIAIGIAVG-MQYLHNLGIIHRDLKPSNILLNKNYLPLICDFGVSR------------------NTLSNVMTKCTGTPQWMAPEIVAG------SE
..  .|.  |  | ..|||...|||||.||.||||       .|||||.                   .| .   . ..||| |||||.. .      ..
SQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKG

YSLSADIFSYGMILYEIATLTRPFEGIPVSTILREVLKG---------------TRPTLPTNIH-------------------PGMRELIIRCWMSDPRL
|. ..|| | |  . | ||   |.   .    . . ...               . |.||....                   | ... | .|   ||. 
YDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNK

RPSFKE
||. ..
RPTASQ
Kinase 90492.m00270.AA TKL-Unique 43-107 25 3e-08 25.36 In-house 1-65 (290) Show / Hide 
Range on Protein: 43-107
Range on HMM: 1-65/290
Sequence Identity: 25% (17 aa)

LEKKIGSGTFGEVWRAKGNDEKGTAAIKILF-NEELSKAELKHFLMEVEILVRCQ-SRFVIPFVGFT
  .|||.|..|.| ..|.. ..   |||... ||..|. ... | .|| .. . . . ..  ..|..
FWNKIGEGGYGQVYKGKWRGYP--VAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYC
Kinase 90492.m00270.AA Dicty4 41-92 32 1e-06 18.11 In-house 1-52 (277) Show / Hide 
Range on Protein: 41-92
Range on HMM: 1-52/277
Sequence Identity: 32% (18 aa)

FQLEKKIGSGTFGEVWRAKGNDEKGTA-AIKIL--FNEELSKAELKHFLMEVEIL
 . |..||.| |||| ...    .|.. |.|.|   |. .. ..|. |. ||.|.
INIEQRIGKGSFGEVYKGTW---RGKEVAVKKLNNHNQNFDENMLNEFRKEVHIM
Kinase 90492.m00270.AA STE 41-105 19 1.8e-05 15.44 In-house 1-97 (359) Show / Hide 
Range on Protein: 41-105
Range on HMM: 1-97/359
Sequence Identity: 19% (19 aa)

FQLEKKIGSGTFGEVWRAKGND-----EKG----------TAAIKILFNEELSK---------------AELKHFLMEVEILVRCQ--SRFVIPFVG
... .|||.|.||.| .|. ..     ..|            |||..  |. ..                |.. .|.|..|. .|.  . ... . |
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYG
Kinase 90492.m00270.AA LRRK 41-72 22 0.000233 11.31 In-house 1-59 (351) Show / Hide 
Range on Protein: 41-72
Range on HMM: 1-59/351
Sequence Identity: 22% (13 aa)

FQLEKKIGSGTFG-EVWRAKGND-------------------------EKG-TAAIKIL
.  |..||.|.|| .| ||| ..                          .. ..|||..
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKW
Kinase 90492.m00270.AA Dicty4-Unclassified 41-92 38 0.000532 9.55 In-house 1-52 (263) Show / Hide 
Range on Protein: 41-92
Range on HMM: 1-52/263
Sequence Identity: 38% (21 aa)

FQLEKKIGSGTFGEVWRAKGNDEKGTAAIKILFNEELSKAE---LKHFLMEVEIL
 |  . || | | .|   |||      |.|. |||   |.    .. |. |||||
IQIDQFIGKGHFSKVH--KGNWKGKDVAVKK-FNENKFKFREEMIQDFKKEVEIL