Gene 81146.m00065 (T.vaginalis)

81146.m00065

Species: T.vaginalis
Alias: 81146.m00065, TvagK0265
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
81146.m00065.AA Protein None 1043 None Fasta, JSON
81146.m00065.kin_dom Protein Kinase Domain None 249 None Fasta, JSON

Protein domain

Protein domains of 81146.m00065.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 81146.m00065.AA TKL 202-443 22 1.1e-86 294.28 In-house 1-364 (364) Show / Hide 
Range on Protein: 202-443
Range on HMM: 1-364/364
Sequence Identity: 22% (85 aa)

IGTGATGNVFKAIHLPTN--------KTVAIKQLNNLDLTDPEI-------------------------ESLRREIAILSSLRHPYLIEFVGATSTPP--
|| |. | |.|...  ..        |.||.|...  .    ..                         . ...|| ..|.|||| .. |.|.   ||  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YWIITDFMDNGS-LYSCLRNNRLNATELTKIAYESADGVAYLHS--------KNIIHRDLKTLNVLVSQDNE--------------AR
            ..|.......|| |.  .         . ..|.. | |..||||        ..|||||||. |.|| ....              . 
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

VCDFGISRSAD---SQIMTG------------------LVGTYNYMAPEVITRA----------------RYTLKADSFSFGMMLWEMLTGQVPFSYVSN
.||||.||. .   .. .|.                   .||...|||||.  .                 |. |.| .|||..|||.||...|..   .
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY

SYQI---------GDLIVKGQRPEFP------------RNTPAQLKDLIQSCWAQNPDSRPTFEQIKSNF
. .|            ..||.||. |             ..| ..|.|.| ||...|..||.|..|.. .
MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 81146.m00065.AA MLK 196-443 30 4.4e-78 265.71 In-house 1-291 (291) Show / Hide 
Range on Protein: 196-443
Range on HMM: 1-291/291
Sequence Identity: 30% (90 aa)

FQLKQQIGTGATGNVFKAIHLPTN---KTVAIKQLN----NLDLTDPEIESLRREIAILSSLRHPY----LIEFVGA-TSTPP-YWIITDFMDNGSLYSC
.|... || |. | |.|.    ..   |.||.|. .        |. |.. ...|. .|. |.||      |.|.|. ...|. . |.. ....||||. 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LRNNR---------------LNATELTKIAYESADGVAYLHSKN---IIHRDLKTLNVLVSQ------DNEARVCDFGISRSADSQ-I-MTGLVGTYNYM
|...|                    . ..|.  | |..||||.    |||||||  |.|...      .  ...||||.||.  .    |..  ||| .|
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWM

APEVITR---ARYTLKADSFSFGMMLWEMLTGQVPFS-YVSNSYQIGDLIVKGQRPEFPRNTPAQLKDLIQSCWAQNPDSRPTFEQIKSNF
|||||..    .|. |.| .|.|..||||||..||.. ...... .   ...|.||  | . |. .| |.. || |.| .||.| || . .
APEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 81146.m00065.AA Pkinase 196-443 26 1.9e-76 265.06 Pfam 1-293 (293) Show / Hide 
Range on Protein: 196-443
Range on HMM: 1-293/293
Sequence Identity: 26% (80 aa)

FQLKQQIGTGATGNVFKAIHLPTNKTVAIKQLNNLDLTDPEIESLRR--EIAILSSLRHPYLIEFVGATSTPPY-WIITDFMDNG----SLYSCLR---N
......|| |. | |.|..|  |.|.||.|...  .  . . ...||  ||.|. .|.||. ... ..  .... .........|    .|.. ..   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NRL--NATELTKIAYESADGVAYLHSKNIIHRDLKTLNVLVSQDNEA----RVCDFGISR---SADSQIMTGLVGTYNYMAPEVIT-RARYTLKADSFSF
...     |. ...|. . |..|.||..|||||||  |.|......     ..||||...      .. ||...||..|||||||  .  |. |.| .|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GMMLWEMLTGQVPFSYVS----NSYQIGDLIVKGQRPEFPRNTP-----------------------AQLKDLIQSCWAQNPDSRPTFEQIKSN--F
| .|.|||.|. ||.  .    | .    .|..  .|..... |                         .||.| .|....| .|||.|||.    |
GCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 81146.m00065.AA Dicty4 196-439 33 1.5e-73 244.67 In-house 1-269 (277) Show / Hide 
Range on Protein: 196-439
Range on HMM: 1-269/277
Sequence Identity: 33% (92 aa)

FQLKQQIGTGATGNVFKAIHLPTNKTVAIKQL--NNLDLTDPEIESLRREIAILSSLRHPYLIEFVGATS----TP-PYWIITDFMDNGSLYSCLRN---
 .  | ||.|. | |.|..     | ||.| |  .| ..   .....|.|..|....||| .. | ||      .|    | | .|  |.||| |..   
INIEQRIGKGSFGEVYKGTW--RGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPS

---NRLNAT--ELTK---IAYESADGVAYLHSKN--IIHRDLKTLNVLVSQDNEARVCDFGISR----SADSQI-MTGLVGTYNYMAPEVITRARYTLKA
    .        ..   .|   | |...||. |  |||||||. | ||.... . |||||.|.      | .  ... .||  .|||||    .|. ||
EQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKA

DSFSFGMMLWEMLTGQVPFS-YVSNSYQIGDLIVK-GQRPEFPRNTPAQLKDLIQSCWAQNPDSRPTFEQI
| .|||..|||.||.| |..   ..  |......  . ||. | ..|. .|.||| ||  .| .||.||.|
DVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEI
Kinase 81146.m00065.AA S_TKc 196-444 27 3.2e-72 247.17 SMART 1-231 (231) Show / Hide 
Range on Protein: 196-444
Range on HMM: 1-231/231
Sequence Identity: 27% (73 aa)

FQLKQQIGTGATGNVFKAIHLPTNKTVAIKQLNNLDLTDPEIESLRREIAILSSLRHPYLIEFVGATSTPPYWIITDFMDN--GSLYSCLRNNR------
... ..|| || | |.|..|  |.. ||||...         |..||||.||.. .||... . ..  .  ........|.  |.|.. .....      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LNATELTKIAYESADGVAYLHSKNIIHRDLKTLNVLVSQDNEARVCDFGISRSADSQIMTGLVGTYNYMAPEVITRARYTL-KADSFSFGMMLWEMLTG
 ..  .  ...|. .....|.||..|||||||  |.|...  .  .||||..|       | ..|| .||||||.    |.  |.|  |.| .|.|||.|
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCG

QVPFSYVSNSYQIGDLIVKGQRPEFPRNTPAQLKDLIQSCWAQNPDSRPTFEQIKS--------NFI
. ||.   . ... ..|.           . ..||.|. |.  .|. |||  ..           ..
YPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 81146.m00065.AA Pkinase_Tyr 196-443 30 1.3e-71 243.12 Pfam 1-270 (270) Show / Hide 
Range on Protein: 196-443
Range on HMM: 1-270/270
Sequence Identity: 30% (82 aa)

FQLKQQIGTGATGNVFKAIHL----PTNKTVAIKQLNNLDLTDPE--IESLRREIAILSSL-RHPYLIEFVGATS--TPP--YWIITDFMDNGSLYSCLR
 .. ...| || |.|.|..       |. .||.| |.. . ....  .|.. ||..|...| .|| .. ..|. .    |  ..|.. .| .|.|.. ||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

NN-----RLNATELTKIAYESADGVAYLHSKNIIHRDLKTLNVLVSQDNEARVCDFGISRSA----DS-QIMTGLVGTYNYMAPEVITRARYTLKADSFS
..     .|.  .| ..... |.| .||.|||.||||| . |.||. .| ...|||| .|         .  .|       ||||.|   ..| | |  |
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

FGMMLWEMLT-GQVP-FSYVSNSYQIGDLI-VKGQRPEFPRNTPAQLKDLIQSCWAQNPDSRPTFEQIKSNF
||  .||..| |. | .  .   ... ..|  .|.| . |.|.|. . ||...||...|. ||||..| . .
FGVLMWEIFTYGEQPTYPGM-SNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 81146.m00065.AA LRRK 196-445 28 5.1e-70 238.94 In-house 1-351 (351) Show / Hide 
Range on Protein: 196-445
Range on HMM: 1-351/351
Sequence Identity: 28% (99 aa)

FQLKQQIGTGATG-NVFKAIHL--------------------------PTNKTVAIKQLNN----LDLTD-----------------------------P
.   .||| |..| .|..|.                               ..||||..|      | .|                              
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTID-NDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCR

EIESLRREIAILSSLRHPYLIEFVGATSTPPYWIITDFMDNGSLYSCLRNNRLNA-----TE-----LTKIAYESADGVAYLHSKN--IIHRDLKTLNVL
   ..|.|..|.|.|.||...  .|  .  |. ........|.||. |.|.. ..     ..     . |||.. |.|..||||.|  |||||||. |.|
AFREFRHEVWIMSHLNHPNIVSLKGF-CIHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNIL

V-SQDNE-----------ARVCDFGISR--SADSQ-IMTGLVGTYNYMAPEVIT---RARYTLKADSFSFGMMLWEMLTGQ-VPFSYVS-N-----SYQI
. | ...           | ..||||||  ...   .  |.||.  .||||..    .  || |.| .|||| ||| ||.|  ||   .        .||
LWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQI

GDLIVKGQRPEFPRN-TPA-----QLKDLIQSCWAQNPDSRPTFEQIKSNFIR
 |.| .|.|| .| .  |       ..||||.||...|..||.|.|| .    
EDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 81146.m00065.AA TKL-Unique 198-443 28 1.7e-69 237.19 In-house 1-290 (290) Show / Hide 
Range on Protein: 198-443
Range on HMM: 1-290/290
Sequence Identity: 28% (84 aa)

LKQQIGTGATGNVFKAIHLPTNKTVAIKQLN-NLDLTDPEIESLRREIAILSSLR-HPYLIEFVGATS----TPP-YWIITDFMDNGSLYSCLR------
    ||.|. |.|.|...    . |||||.. | |.   ... ...|. ... |. || .  ..|..     .|| . |...... ||||. |       
FWNKIGEGGYGQVYKGKW--RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

-----NNRLNATELTKIAYESADGVAYLHSKN--IIHRDLKTLNVLVSQD-----NEARVCDFGISRSADSQ---IMT--------GLVGTYNYMAPEVI
     |. ||     |.|   |.|  |||...  |||||||..|.||...     . ...||||.|.....    . .        . .|....|||||.
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

TR--ARYTLKADSFSFGMMLWEMLTGQV------PFSYVSNSYQIGDLIVK---GQRPEFPRNTPAQLKDLIQSCWAQNPDSRPTFEQIKSNF
..  . |. |.| .|||..|||..|...      |.. . ...|.  .. .   ..||. | . | ...|||| ||...|. ||.|..| .  
RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGM-DQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 81146.m00065.AA STE 196-444 23 1.9e-65 223.72 In-house 1-359 (359) Show / Hide 
Range on Protein: 196-444
Range on HMM: 1-359/359
Sequence Identity: 23% (84 aa)

FQLKQQIGTGATGNVFKAIHL------PTNKT---------VAIKQLN---------------NLDLTDPEIESLRREIAILSSLR--HPYLIEFVGATS
... ..|| ||.| |.||..       .|...         .||||.|               . .  . |.... .|| |.. ..  ||. ... |.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TPP--------YWIITDFMDNGSLYSCLRNN---------------RLNATELTKIAYESADG-VAYLHSKNIIHRDLKTLNVLVSQDNEARVCDFGISR
            ||.  .||.||| . ....               |.. ... .|...   |  .||||..|||||.|  |.|.     .  ||||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

SADS------------------QIMTGLVGTYNYMAPEVITRAR------YTLKADSFSFGMMLWEMLTGQVPF---SYVSNSYQIGDL-----------
. ..                  |  . .|||  .||||||.. .      |. |.|  |.| ...||.||..|.   .. .. ..| .            
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

IVKGQRPEFPRNTP-------------------AQLKDLIQSCWAQNPDSRPTFEQIKS---NFI
||.|. | .| ..                      .|| |. |   .|. ||| .|  .    ||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 81146.m00065.AA TK 196-443 16 2.7e-65 217.58 In-house 1-486 (486) Show / Hide 
Range on Protein: 196-443
Range on HMM: 1-486/486
Sequence Identity: 16% (82 aa)

FQLKQQIGTGATG---NVFKAIHLPTNK-------------------------TVAIKQLNNLDLTDPEIESL---------------RREIAILSS--L
 .| ...| |. |    |.|..  . |.                         .||.|.|   | ...| . .                .|......  .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHPYLIEFVGATST-------------PPYWIITDFMDNGS----LYSCLRNNR----------------------------------------------
.|| .. ..|. .              .|..|.. .|..|.    | . ||..|                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LNATELTKIAYESADGVAYLHSK------NIIHRDLKTLNVLVSQDNE-----------ARVCDFGIS-
                               |.  .|  ...  |.| .|||||      |..|||| . |.||...|            ....||| | 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-------RSADS-QIMTGLVGTYN---------------------------YMAPEVIT---------RARYTLKADSFSFGMMLWEMLT-GQVPFSY-V
       |  .| .  .   . .                            .||||...           ..| | | .||| ..||..| ||.|.   .
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

SN--------SYQIGDLIVKG--------------QRPEFPRNTP--------------AQLKDLIQSCWAQNPDSRPTFEQIKSNF
||          .. .....|               |.. | . |              . . ||.|.||. .|. ||||.|... .
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 81146.m00065.AA TyrKc 196-443 28 1.4e-63 218.41 SMART 1-280 (280) Show / Hide 
Range on Protein: 196-443
Range on HMM: 1-280/280
Sequence Identity: 28% (82 aa)

FQLKQQIGTGATGNVFKAIHLPTNKTVAIKQLNNLDLTDPEIESLRREIAILSSL--RHPYLIEFVGATST--------PPYWIITDFMDNGSLYSCLRN
 .|....| || | |.|..      .||.| |..       .| ..||. |...|  .|| .. ..|. ..        .|..|.. .|..|.| . ||.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

NR--LNATELTKIAYESADGVAYLHSKNIIHRDLKTLNVLVSQDNEARVCDFGISRSADSQ--------IMT-----GLV--GTYNYMAPEVITRARYTL
.|  |.  .| ....  |.| .||||||.||||| . |.||. .. ....||| ||  ..           .     |      .  ||||.|   ..| 
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KADSFSFGMMLWEMLT-GQVPFSYV----SNSYQIGDLIVKGQRPEFPRN--------TPAQLKDLIQSCWAQNPDSRPTFEQIKSNF
| | .||| ..||..| || | . .     . ...  .. .| |.. | |         |. . .....||. .|..||||..|.. |
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 81146.m00065.AA HH498 196-443 31 1.4e-57 180.97 In-house 1-284 (284) Show / Hide 
Range on Protein: 196-443
Range on HMM: 1-284/284
Sequence Identity: 31% (89 aa)

FQLKQQIGTGATGNVFKAIHLPTNKTVAIKQLNNLD-LTDPE-----IESLRREIAILSSLRHPYLIEFVGATSTPP--YWIITDFMDNGSLYSCL----
.  . .|| |. |.|.|      || ||.|       .   .        . ||. |.. | ||. . ||.|.   |    |.|.. |||||.| |    
IEFHEKIGSGSFGKVYKGEW--RNKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYACCDDPSQFAIVTQYCDNGSLFSILNTIP

----------RNNR-----LNATELTKIAYESADGVAYLHS---KNIIHRDLKTLNVLVSQDNEARVCDFGISR---SADSQIMTGLVGTYNYMAPEVIT
           |..     .       |. . | |  |||.   . ||||||   |.|. .|  | | |||.||   . .   ||   |   .||||| .
IGGAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFS

-RARYTLKADSFSFGMMLWEMLTGQVPFSYVSNSYQIGDLIVKGQRPEFPRN----TPAQLKDLIQSCWAQNPDSRPTFEQIKSNF
   .|. |.| ||..| .|||.|. |||.         ..  .  ||  |       |..   ||| || ..|..||.| ||    
QCQKYSIKVDVFSYAMCIWEMHTREVPFHHYKPAAAAAEMAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL
Kinase 81146.m00065.AA Dicty5 197-447 32 3e-55 188.63 In-house 2-260 (260) Show / Hide 
Range on Protein: 197-447
Range on HMM: 2-260/260
Sequence Identity: 32% (86 aa)

QLKQQIGTGATGNVFKAIHLPTNKTVAIKQLNNLDLTDPEIESLRREIAILSSLR--HPYLIEFVGA-TSTPPY-WIITDFMDNGSLYSCLRNNRL----
 . . |  || | |.. |     . |||| .        ....  ||..|.|     || .| . || .    |  ..| .  |||| . |.  |     
SFHDWIASGASGRVYNGIY--KGMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQ

NATELTK--IAYESADGVAYLHSKNIIHRDLKTLNVLVSQDNEARVCDFGISR-SADSQIMTGLVGTYNYMAPEVITRARYTLKADSFSFGMMLWEMLTG
.    ..  .|   | .  .|||.|||||||| .|.|.  . .. . |||.||  .    ||  ||| ..||.|. .   |. |.| .|||  ||||.| 
PIAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEMFTR

QVPFSYVSNSYQIGDLIVKGQRPEFPRNTPAQLKDLIQSCWAQNPDSRPTFEQIKSNFIRSR
  |.  . |.  |  .. || ||. |   |     || .|| | |  ||.|  |   | .  
KEPYDNI-NNWNIPVMVMKGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase 81146.m00065.AA Dicty4-Unclassified 196-443 31 1e-54 185.8 In-house 1-263 (263) Show / Hide 
Range on Protein: 196-443
Range on HMM: 1-263/263
Sequence Identity: 31% (83 aa)

FQLKQQIGTGATGNVFKAIHLPTNKTVAIKQLNNLDLTDP--EIESLRREIAILSSLRHPYLIEFVGATSTP-----PYWIITDFMDNGSLYSCLR----
 |  | || |.   | | .     | ||.| .|          |.  ..|..|| |. || |.   |.   |      . |.. ||  | |         
IQIDQFIGKGHFSKVHKGNW--KGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPS

-NNR---LNATELTKIAYESADGVAYLHSKNIIHRDLKTLNVLVSQDNEARVCDFGISRSAD-SQIMTGLVGTYNYMAPEVITRARYTLKADSFSFGMML
  ..   |. |   |.| . | | ..||..|.||||.|  |.|.  .. ... ||||||  |  . ||   ||    .||.     |. |.| .|..|||
EQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMML

WEMLTGQVPFSYVSNSYQIGDLIV-KGQRPEFPRNTPAQLKDLIQSCWAQNPDSRPTFEQIKSNF
.|..||  |.  .     .. ..  |. ||. | | .  .| ||  ||   |  |||..||    
YELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL