96267.m00149

Species: T.vaginalis
Alias: 96267.m00149, TvagK0438
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
96267.m00149.AA Protein None 451 None Fasta, JSON
96267.m00149.kin_dom Protein Kinase Domain None 256 None Fasta, JSON

Protein domain

Protein domains of 96267.m00149.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH 96267.m00149.AA PH 5-99 13 9.8e-10 39.59 SMART 1-82 (82) Show / Hide
Range on Protein: 5-99
Range on HMM: 1-82/82
Sequence Identity: 13% (13 aa)

PVLAGTLKRRSGKVSMWRQVKCELYPGKMVFKHKSTGDIAEILKLNSMTTILREEGDSHNTFIVKDSNETLELAADSSESLQNWIKKFKELTLHQ
... |.|...|     |... . |... ... ...  .  ... |... |. . .     .| ..  ..|......|.|..| |.. ..... ..
VIKEGWLYKKS--K-RWKKRWFVLFNDCLYYYKDK--KPKGSIPLSDC-TVRE-P-----CFEIHH-DRTYYFQCESEEEMQEWMQAIQKAIHNN

PH 96267.m00149.AA PH 5-97 12 3.9e-08 31.97 Pfam 1-92 (92) Show / Hide
Range on Protein: 5-97
Range on HMM: 1-92/92
Sequence Identity: 12% (12 aa)

PVLAGTLKRRSGKVSMWRQVKCELYPGKMVFKHKSTGDIAEILKLNSMTTILREEGD--SHNTFIVKDSNE-TLELAADSSESLQNWIKKFKELTL
... | |.... | . |... . | ......  ...       ...  .  ...  |   ...| ..  .. |....|.|.|... |.. ....  
VIKEGWLHKKG-KRKSWKKRWFVLFNNCLYYYKDDK--YRPKGSIPLSDCQVTKVPDNKRPHCFQIRT-DRRTYYFQAESEEEMNDWMQAIQSACR

Kinase 96267.m00149.AA AGC 107-362 26 6.1e-142 369.58 In-house 1-395 (395) Show / Hide
Range on Protein: 107-362
Range on HMM: 1-395/395
Sequence Identity: 26% (107 aa)

FRIIRTLGSGFYGKVLLAEHK------QSKKIYAIKSIHKSR-LVNDD--KINTIFSE------------RNILLLSQ----------HPFIVG-IKFSF
|......| | .||| |...|      ...|.||.| . |..  | ..  ..  . .|            |||| . .          |||||   ..||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QNDKK--FYLGLEYVS---------GG-ELFKLIE---TGHCVPFQQVRFYVME-------VALALDYLHS-IGVIYRD-LKLENVLMTKSGHIKLTDFG
|....   |. .||..         || |||  .       . . ...|||  |       ..|||.||||  |.|.|| ||.||.|... |||||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSKIVADGK-----------------------------------------------ADNSTTSTFCG--TPEYLAPEMILSKDYGIEIDWWA--LGVFTY
|.|.. ...                                                .. .|.||||  ||||.|||..    || . |||.  ||.. |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EFSYTITPFVGKTNK----------KTYDNIL------HEEPKFP----------PNADPNLVSFIMMCLRKDPTKRAT----------FKDIKKHPFF
|. . ..|| |...           .....|.      ....|||          .. .|.....| ..| |||.|| .          ...||.||.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF

Kinase 96267.m00149.AA Akt 107-362 39 1.7e-108 347.95 In-house 1-264 (264) Show / Hide
Range on Protein: 107-362
Range on HMM: 1-264/264
Sequence Identity: 39% (105 aa)

FRIIRTLGSGFYGKVLLAEHKQSKKIY-AIKSIHKSRLVNDDKINTIFSERNILLLSQHPFIVGIKFSFQNDKKFYLGLEYVSGGELFKLIETGHCVPFQ
|.... ||.| .|||.|.. |...|.| |.|.. |..... ...  .. |||||   .|||||. ..|||. .| |. ..|..||||| ..      . .
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

QVRFYVMEVALALDYLHSIGVIYRD-LKLENVLMTKSGHIKLTDFGLSKIVADG-KADNSTTSTFCGTPEYLAPEMILSKDYGIEIDWWA-LGVFTYEFS
. |||. |. ||...||| ..|||| ||.||.|| | |||.||||||.|   .. . |. .| ||||||||||||... ....   |||. ||...||. 
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCK---ENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMM

YTITPFVGKTNKKTYDNILHEEPKFP--PNADPNLVSFIMMCLRKDPTKRA-----TFKDIKKHPFF
.   ||  . ... ...|. .. |||  .. .|.  ..|  .| |||.||      . ..|| ||.|
CGRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF

Kinase 96267.m00149.AA SGK 107-362 37 1.4e-102 317.65 In-house 1-283 (283) Show / Hide
Range on Protein: 107-362
Range on HMM: 1-283/283
Sequence Identity: 37% (108 aa)

FRIIRTLGSGFYGKVLLAEHKQS------------------KKIYAIKSIHKSRLV-------NDDKINTIFSER-NILLLSQHPFIVGIKFSFQNDKKF
|... ..| | .|||....||.                   .|.||.| . |   .       .  . . | .|| .|| .  |||||. ...||...| 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLGLEYVSGGELFKLIETGHCVPFQQVRFYVMEVALALDYLHSIGVIYRDLKLENVLMTKSGHIKLTDFGLSKIVADGKADNSTTSTFCGTPEYLAPEMI
|. ..|| |||.|  .    . |  ..|||. |...||.||||. .|||||| ||.|    ||..||||||.|    | ..| ||.||||||||||||..
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCK---EGIKTNDTTFTFCGTPEYLAPEVL

LSKDYGIEIDWWALGVFTYEFSYTITPFVGKTNKKTYDNILHEEPKFPPNADPNLVSFIMMCLRKDPTKRATFK----DIKKHPFF
. . .. . ||| || . ||. | . ||  .  .  ||||.... ..||.  .   . |   | |||.||   |    .||.||||
RKQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF

Kinase 96267.m00149.AA S_TKc 107-362 33 7.4e-94 319.04 SMART 1-231 (231) Show / Hide
Range on Protein: 107-362
Range on HMM: 1-231/231
Sequence Identity: 33% (92 aa)

FRIIRTLGSGFYGKVLLAEHKQSKKIYAIKSIHKSRLVNDDKINTIFSERNILLLSQHPFIVGIKFSFQNDKKFYLGLEYVSG--GELFKLIETGHC---
..|.|..|.| .||| .. || ...|.||| |.          ..| .|..||   .||.|| .. .||. ...|. .||..|  |.||..|.   .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---VPFQQVRFYVMEVALALDYLHSIGVIYRDLKLENVLMTKSGHIKLTDFGLSKIVADGKADNSTTSTFCGTPEYLAPEMILSKDYGI-EIDWWALGVF
    |  ..|||. ....||.|.|| |.|.|||| ||.|...  |||..||||....          .||||||.|.|||..    ||  ..|||..|. 
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

TYEFSYTITPFVGKTNKKTYDNILHEEPKFPPNADPNLVSFIMMCLRKDPTKRATFKDIKK-------HPFF
 ||. .  .||   . ......|.          .| . .||. ||.|||.|| |  .. .       ||.|
LYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 96267.m00149.AA AktR 107-362 37 1.9e-93 316.76 In-house 1-268 (268) Show / Hide
Range on Protein: 107-362
Range on HMM: 1-268/268
Sequence Identity: 37% (102 aa)

FRIIRTLGSGFYGKVLLAEHK-QSKKIYAIKSIHKSRLVNDDKINTIFSERNILL-LSQHPFIVGIKFSFQNDKKFYLGLEYVSGGELFKLIETGHCVPF
|.... ||.| .||| |...| ...|.||.|.|.|. ...  ..  .  ||||.  ...|||||  ...||...| .. .||. |||||  . . .    
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

QQVRFYVMEVALALDYLHSI-GVIYRDLKLENVLMTKSGHIKLTDFGLSK--IVADGKADNSTTSTFCGTPEYLAPEMILS-KDYGIEIDWWALGVFTYE
.|.|||  .. |||.|||.   .|||||| || |. . ||.|.|||||||  ..   .... .. .|||||||.|||||.  | ..  .||||.|.| ||
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFM---MHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYE

FSYTITPFVGKTNKKTYDNILHEE-PKFPPNADP--NLVSFIM-MCLRKDPTKRAT-----FKDIKKHPFF
  . ..||  | ..  ...|. ..  |||.....  .. ..|   .| |.|.|| .     ...||.||.|
MVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF

Kinase 96267.m00149.AA RSK 110-362 37 2.2e-87 296.64 In-house 1-278 (278) Show / Hide
Range on Protein: 110-362
Range on HMM: 1-278/278
Sequence Identity: 37% (104 aa)

IRTLGSGFYGKVLLAEHK---QSKKIYAIKSIHKSRLVNDDK-INTIFSERNILLLSQ-HPFIVGIKFSFQNDKKFYLGLEYVSGGELFKLIE-TGH--C
.. || | |||| |   .   ....||| | ..|. .|. .| . . . |||||...| |||||  . .|| ..|.|| .||..|||||. ..  .|  |
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

VPFQQVRFYVMEVALALDYLHSIGVIYRDLKLENVLMTK---SGHIKLTDFGLSKIVADGKAD-NSTTSTFCGTPEYLAPEMIL---SKD-YGIEIDWWA
     ..||  |..||...||. |.|.||||.||.| .    .|||||||||..|.    ..| |. | |||.| ||.||||.     .  ..   ||| 
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF---RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWS

LGVFTYEFSYTITPFVG---KTNKKTYDNILHEE--PKFP--PNADPNLVSFIMMCLRKDPTKRAT-----FKDIKKHPFF
|||  ||     .|| |   .. |.. ..|.. .  ...|  ..  ..  ..| ..| .|| || .      ..||.||.|
LGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase 96267.m00149.AA PKA 107-362 41 1.5e-84 287.21 In-house 1-263 (263) Show / Hide
Range on Protein: 107-362
Range on HMM: 1-263/263
Sequence Identity: 41% (112 aa)

FRIIRTLGSGFYGKVLLAEHKQSKKIYAIKSIHKSRLVNDDKINTIFSERNILLLSQHPFIVG-IKFSFQNDKKFYLGLEYVSGGELFKLIETGHCVPFQ
| ||.|||.| .|.| |. ||.|...||.| . |.. |    .  . .|.|||.. .|||||   ...||.|.. |. .|||.|||.|. .    . . .
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

QVRFYVM-EVALALDYLHSIGVIYRDLKLENVLMTKSGHIKLTDFGLSKIVADGKADNSTTSTFCGTPEYLAPEMILSK-DYGIEIDWWALGVFTYEFSY
. .||.. .. |||.||||   |||||| || |. | ||||.|||| .| | |       |.| ||||||||||.|.||  .|  .||||||.  ||.  
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD------RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLA

TITPFVGK--TNKKTYDNILHEEPKFPPNADPNL---VSFIMMCLRKDPTKRA-TFK----DIKKHPFF
 ..||  .  .  ..|. |.  . |||.. |...    ..|   | .|.|||  ..|    |||.|..|
GYPPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF

Kinase 96267.m00149.AA Pkinase 107-362 31 2.5e-84 291.28 Pfam 1-293 (293) Show / Hide
Range on Protein: 107-362
Range on HMM: 1-293/293
Sequence Identity: 31% (95 aa)

FRIIRTLGSGFYGKVLLAEHKQSKKIYAIKSIHKSRLVNDDKINTIF-SERNILLLSQHPFIVGIKFSFQNDKKFYLGLEYVSGG----ELFKLIE--TG
..|.|..||| .|.| .. || . ||.|.| | |..   . ... .  ||  |..  .||.|| .. .|..... |. .||. ||    .|| .|.   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

HCV--PFQQVRFYVMEVALALDYLHSIGVIYRDLKLENVLMTKSGHI----KLTDFGLSKIVADGKADNSTTSTFCGTPEYLAPEMIL-SKDYGIEIDWW
 |.  . ....||. ... .|.|.|| |.|.||||.||.|. . |||    |..||||.| .      || ..||||||.|.||| |. ...|| ..|.|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

ALGVFTYEFSYTITPFVGK------TNKKTYDNILHEEPKFPPNAD---------------------PNLVSFIMMCLRKDPTKRATFKDIKKHPFF
..|.  ||.    .|| |.      . .. ...|.. ...|.   .                     ... .||  ||.|||.|| |...|..||.|
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 96267.m00149.AA MAST 107-362 29 3.6e-84 271.18 In-house 1-334 (334) Show / Hide
Range on Protein: 107-362
Range on HMM: 1-334/334
Sequence Identity: 29% (100 aa)

FRIIRTLGSGFYGKVLLAEHKQSKKIYAIKSIHKSRLVNDDKINTIFSERNILLLSQHPFIVGIKFSFQNDKKFYLGLEYVSGGELFKLIETGHCVPFQQ
| .|. .. | |||| |..|| .....|.| | || . |   ... ..||||| ..| ||.| .  ||| ... .. .||..|| ...|..   . .   
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

VRFYVMEVALALDYLHSIGVIYRDLKLENVLMTKSGHIKLTDFGLSKI--------VADG---------------KADNSTTSTF---------------
...|. |..|.|.|||| | . |||| .|.| ...||||||||||||.        .  |               | .. ....                
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDLNMMYEGYTPPNIFNNSTDPMNKNQQDYSQFPGDFGINGNTNKNQIQ

------------------------CGTPEYLAPEMILSKD-YGIEIDWWALGVFTYEFSYTITPFVGKTNKKTYDNILHEE---PKFPPNADPN---LVS
                        ||||.|.||| || .. .|. .|||..|.  |||   ..||...|  ....|||...    ..|.  |.|     |
QQQEQPQCQQQNMRPHNIHQNKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMS

FIMMC-----LRKDPTKRATFK----DIKKHPFF
   ..     |  || || ...    ..|.||||
PEAQDLIEKLLQPDPRKRLGANNGADEVKQHPFF

Kinase 96267.m00149.AA PKC 107-362 38 1.6e-82 267.31 In-house 1-262 (262) Show / Hide
Range on Protein: 107-362
Range on HMM: 1-262/262
Sequence Identity: 38% (102 aa)

FRIIRTLGSGFYGKVLLAEHKQSKKIYAIKSIHKSRLVNDDKINTIFSERNILLL-SQHPFIVGIKFSFQNDKKFYLGLEYVSGGELFKLIETGHCVPFQ
|. .. || | .|||.|||.|.....|||| . |   . || .     |. .| | ..||| ..   .||   . .  .||| || |   |   .  . .
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

QVRFYVMEVALALDYLHSIGVIYRDLKLENVLMTKSGHIKLTDFGLSKIVADGKADNSTTSTFCGTPEYLAPEMILSKDYGIEIDWWALGVFTYEFSYTI
. |||  |...|| .||. |.|||||||.|||... ||||..|||..|   ..  . .|||||||||.|.||| .  ..||  .||||.||  ||.    
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCK---ENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQ

TPFVGKTNKKTYDNILHEEPKFPPNADPNLVSFIMMCLRKDPTKRATF--------KDIKKHPFF
 || |..     ..|.|..| .|       || .   . |.|.||           .||..||||
SPFHGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF

Kinase 96267.m00149.AA Ciliate-E2 107-362 25 7.5e-80 271.6 In-house 1-365 (365) Show / Hide
Range on Protein: 107-362
Range on HMM: 1-365/365
Sequence Identity: 25% (95 aa)

FRIIRTLGSGFYGKVLLAEH-----------------------KQSKKIYAIKSIHKSRLVNDDKINTIF----------SERNILLLSQHPFIVGIKFS
. .|. .|.| .|.| ....                       |. .||||.|...|. . .  ... |.           |.||| . .||.|. .. .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--NDKKFYLGLEYVSGGELFKLIE-----------------TGHCVPF--QQVR-------FYVMEVALALDYLHSIG-VIYRDLKLENVLMTKSGHI
||  .|...|| .||..||.||..|.                   ..  .  |...       ||. .. ||| |||| . .|.||.|.||.|.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLTDFGLSKIVA----------------DGKADNSTTST-------------FCGTPEYLAPEMILSKD---------YGIEIDWWALGVFTYEFSYTIT
|..||||||..                 . | |.|.|..             .||||.|.|||.. .|.         |. ..|.|.|||  ||. .  .
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFVGKTNKKTYDNILHEEPKFPPN------------------ADPNLVSFIMM----CLRKDPTKRAT-FKDIKKHPFF
||        ...|.  . .||..                   ...   .|      .| ||| || | ...|..||.|
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 96267.m00149.AA Ciliate-E2-Unclassified 107-362 26 8.7e-78 264.73 In-house 1-352 (352) Show / Hide
Range on Protein: 107-362
Range on HMM: 1-352/352
Sequence Identity: 26% (95 aa)

FRIIRTLGSGFYGKVLLAEHKQSKKIYAIKSIHKSRLVNDDKINT---------IFSERN-------------ILLLSQHPFIVGIKFSFQNDKKFYLGL
..||...|.| .||| ...||. |..||.| ..|.. ... .|..         .  ...             ||| ..|||||   . ||.....|. .
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYVSGGELFKLIET-----------------GHCVPFQQVR-----FYVMEVALALDYLHSIG-VIYRDLKLENVLMTKSG---HIKLTDFGLSKIVA--
||. ||.|.. |.                  ..... ||..     ||  .. ..|.|||. . .|.||.|.||.|....|   .||..|||.||     
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

---DGKA--------DNSTTSTFCGTPEYL----APEMILSKDYG----IEIDWWALGVFTYEFSYTITPFVGKTNKK----------------TYDNIL
   | .         ..  ..||||||.|.    |||.. .. |.    ...|.|.|||  ||. .   || ... ..                 |.||.
NNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

HEEPKFPP--------NADPNLVSFIM----MCLRKDPTKRATFKDIKKHPFF
  ...||.        . .|.   ||      .| |.| || ||..|..||.|
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 96267.m00149.AA TyrKc 107-362 21 1.3e-17 62.02 SMART 1-280 (280) Show / Hide
Range on Protein: 107-362
Range on HMM: 1-280/280
Sequence Identity: 21% (63 aa)

FRIIRTLGSGFYGKVLLAEHKQSKKIYAIKSIHKSRLVNDDKINTIFSERNILLLS--QHPFIVGIKFSFQND-------KKFYLGLEYVSGGELFKLIE
 . ...||.|..|.| ... |      |.|.....       .  . .| .|.     .|| || .      .       .  .. .||...| | . . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

TGHC-VPFQQVRFYVMEVALALDYLHSIGVIYRDLKLENVLMTKSGHIKLTDFGLSKIVADG----KADNSTTSTF--CGTP----EYLAPEMILSKDYG
  .  .. ..   .   .|   .|||| ..| |||   |.| .. ...| .|||||. . |.     ..   ...   .|        .||| |  . . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

IEIDWWALGVFTYE-FSYTITPFVG-----KTNKKTYDNILHE-EPKFPPN--------ADPNLVSFIMMCLRKDPTKRATFKDIKKHPFF
.. | |. ||  .| |.|  .|  |     ..|.  . .. .   .. |||        . . . . . .| . || .| ||..|  | .|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase 96267.m00149.AA Pkinase_Tyr 107-255 22 8.7e-08 26.99 Pfam 1-161 (270) Show / Hide
Range on Protein: 107-255
Range on HMM: 1-161/270
Sequence Identity: 22% (37 aa)

FRIIRTLGSGFYGKVLLAEHK----QSKKIYAIKSIHKSRLVNDD-KINTIFSERNILLLS-QHPFIVGIKFSFQ-NDKK--FYLGLEYVSGGELFKLIE
 .....||.| .|.| ... |    . |   |.|.. |     .. ..   ..| .|.    .|| ||         ..    |. .||. .| | .   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

T----GHCVPFQQVRFYVMEVALALDYLHSIGVIYRDLKLENVLMTKSGHIKLTDFGLSKIV
.    .. .. ..   . ...| ...||.|.. | |||   |.| |.....| .||||.. .
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI

Kinase 96267.m00149.AA S_TK_X 363-417 24 0.000408 11.26 SMART 1-79 (79) Show / Hide
Range on Protein: 363-417
Range on HMM: 1-79/79
Sequence Identity: 24% (19 aa)

EGISWDDVLN--KKITPPRKPKAK-------------PATSRLSKKRRRTESDATFVPHQNA---------FDGFSFAG
 || ||...|  |.|.|| ||| |             |   . . .   ... ..   .||.         | ||..  
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF

Kinase 96267.m00149.AA Pkinase_Tyr 328-362 28 0.002378 11.97 Pfam 238-270 (270) Show / Hide
Range on Protein: 328-362
Range on HMM: 238-270/270
Sequence Identity: 28% (10 aa)

PPNADPNLVSFIMMCLRKDPTKRATFKDIKKHPFF
|.|. . . . ...| ..|| .| ||..|  | ..
PENCPDEIYDLMKQCWHYDPEDRPTFSEI--HEQL