Gene 86485.m00553 (T.vaginalis)

86485.m00553

Species: T.vaginalis
Alias: 86485.m00553, TvagK0388
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
86485.m00553.AA Protein None 474 None Fasta, JSON
86485.m00553.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 86485.m00553.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH 86485.m00553.AA PH 6-101 19 1.7e-10 42.11 SMART 1-82 (82) Show / Hide 
Range on Protein: 6-101
Range on HMM: 1-82/82
Sequence Identity: 19% (19 aa)

LVTSGWLKRHRFLAFWAKRYCVLTGTDFCIYKSEDLTSFDFHIEILPTTTIEIIDEVHDPRFRIIDNMGKENVFETPNTEMLMRWVLALRGCTLNN
.. .|||..   .  | ||..||..  ...||..       .....| ..... . .    |.|.   . . .| ... | . .|. |.. .. ||
VIKEGWLYKKS-K-RWKKRWFVLFNDCLYYYKDK------KPKGSIPLSDCTVRE-P---CFEIHH-DR-TYYFQCESEEEMQEWMQAIQKAIHNN
PH 86485.m00553.AA PH 6-99 19 8e-06 23.65 Pfam 1-92 (92) Show / Hide 
Range on Protein: 6-99
Range on HMM: 1-92/92
Sequence Identity: 19% (19 aa)

LVTSGWLKRHRFLAFWAKRYCVLTGTDFCIYKSEDLTSFDFHIEILPTTTIEIIDEVHDP----RFRIIDNMGKENVFETPNTEMLMRWVLALRGCTL
.. .|||..  ..  | ||..||...  ..||...      .  ..|  ..  ...|.|.     |.|.  .... .|.... | . .|. |.. .  
VIKEGWLHKKGKRKSWKKRWFVLFNNCLYYYKDDK----YRPKGSIPLSDC-QVTKVPDNKRPHCFQIRT-DRRTYYFQAESEEEMNDWMQAIQSACR
Kinase 86485.m00553.AA AGC 109-360 30 8.3e-166 432.71 In-house 1-395 (395) Show / Hide 
Range on Protein: 109-360
Range on HMM: 1-395/395
Sequence Identity: 30% (123 aa)

FRVLKVIGRGFYGKVTLCEHI------ATKEIVAIKSIHKSR---LIQQNKVTTVISE------------RNILAKAQ----------HPFIVN-LKFAF
|..|||||.| .||| |...       .|... |.| . |..   ....|.|  ...|            ||||.|..          |||||. |...|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QSPSK--FYLGLEYVP---------GG-ELFFHMQ---RYGNIRLDDCKIYIAE-------ILLALNHLHS-LGVIYRD-LKPENILLDANGHIKLTDFG
|....   |. .||.|         || |||.|.|   ..|    . ...|.||       |.||| .||| .|.|.|| |||||||||..|||||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSKNLAHE---------------------------------------------------VHTSTFCG--TTEYLAPEVVNHQPYTYSVDWWA--LGVLTY
|.| .  .                                                   . |.||||  | ||.|||..    |....|||.  ||.| |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

ELLFGTTPFAHQN----------RAKMFRNIL------DNEPQFP----------PNFNQEAIDFIKAMLTKDPLKRPT----------FEQIKQMKFF
|.|.| .|| ..|          ...|| .|.       ....||          ..| .|| |.|| .|.||| ||..          .|.||. ..|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 86485.m00553.AA Akt 109-360 45 7.4e-131 420.57 In-house 1-264 (264) Show / Hide 
Range on Protein: 109-360
Range on HMM: 1-264/264
Sequence Identity: 45% (120 aa)

FRVLKVIGRGFYGKVTLCEHIATKEIV-AIKSIHKSRLIQQNKVTTVISERNILAKAQHPFIVNLKFAFQSPSKFYLGLEYVPGGELFFHMQRYGNIRLD
|..|||.|.| .||| |..  .|...  |.|.. |...||.|.|  .. ||||| . .|||||||...||.. | |. ..|..|||||.|.|| . .  |
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

DCKIYIAEILLALNHLHSLGVIYRD-LKPENILLDANGHIKLTDFGLSK-N-LAHEVHTSTFCGTTEYLAPEVVNHQPYTYSVDWWA-LGVLTYELLFGT
  . |.||| ||. |||| ..|||| |||||||.|..|||.||||||.| | . .   | ||||| ||||||. | . .| .||||. ||...||...| 
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

TPFAHQNRAKMFRNILDNEPQFP--PNFNQEAIDFIKAMLTKDPLKRP-----TFEQIKQMKFF
 || .|.. .|| .|. .. .||  ... .|. |.|. .|.||| ||.     . ..||.  .|
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 86485.m00553.AA SGK 109-360 42 4.8e-121 375.7 In-house 1-283 (283) Show / Hide 
Range on Protein: 109-360
Range on HMM: 1-283/283
Sequence Identity: 42% (119 aa)

FRVLKVIGRGFYGKVTLCEHIAT------------------KEIVAIKSIHKSRLI-------QQNKVTTVISER-NILAKAQHPFIVNLKFAFQSPSKF
|. ||||| | .||| . .| ..                  . . |.| . |   |       . ...  . .|| .|| .  |||||||..||| . | 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLGLEYVPGGELFFHMQRYGNIRLDDCKIYIAEILLALNHLHSLGVIYRDLKPENILLDANGHIKLTDFGLSK-NLAHEVHTSTFCGTTEYLAPEVVNHQ
|. ..|| |||.|.|.|| .    |  ..| ||| .|| .|||. .|||||||||||||. ||..||||||.| . ...  |.||||| ||||||| ..|
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

PYTYSVDWWALGVLTYELLFGTTPFAHQNRAKMFRNILDNEPQFPPNFNQEAIDFIKAMLTKDPLKR----PTFEQIKQMKFF
|.  .|||| || . ||...|  || ..|.. |. ||.  . |.||..  .| | |.  |.||| ||      |..||.  ||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 86485.m00553.AA AktR 109-360 40 2.3e-112 379.58 In-house 1-268 (268) Show / Hide 
Range on Protein: 109-360
Range on HMM: 1-268/268
Sequence Identity: 40% (109 aa)

FRVLKVIGRGFYGKVTLCEHI-ATKEIVAIKSIHKSRLIQQNKVTTVISERNILA-KAQHPFIVNLKFAFQSPSKFYLGLEYVPGGELFFHMQRYGNIRL
|.|.|..|.| .||| |...   .....|.|.|.|. .|..|.   .| ||||.. ...|||||.|...||. .| .. .||.||||||.| .. . .  
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

DDCKIYIAEILLALNHLHSL-GVIYRDLKPENILLDANGHIKLTDFGLSK--NLA-HEVHTSTFCGTTEYLAPEVVNH-QPYTYSVDWWALGVLTYELLF
.. ..|.|.||||| .||.   .||||||||||||| .||.|.|||||||  .    . .. .|||| ||.|||...  .....||||||.|.. ||...
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GTTPFAHQNRAKMFRNILDNE---PQFPPNFNQEAIDFIK-AMLTKDPLKRPT-----FEQIKQMKFF
| .|| |.|.  || .|.  .   ...|..| ... |.|.   | |.| ||..     .|.||  ..|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 86485.m00553.AA RSK 112-360 43 1.7e-111 376.75 In-house 1-278 (278) Show / Hide 
Range on Protein: 112-360
Range on HMM: 1-278/278
Sequence Identity: 43% (121 aa)

LKVIGRGFYGKVTLCEHI---ATKEIVAIKSIHKSRLIQQNK-VTTVISERNILAKAQ-HPFIVNLKFAFQSPSKFYLGLEYVPGGELFFHMQRYGN---
||| |.| |||| ||  .   .|. | | | ..|. ..| .| . ..  |||||.  | |||||.|. ||| ..|.|| .||..||||| | |. .    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

IRLDDCKIYIAEILLALNHLHSLGVIYRDLKPENILLDA---NGHIKLTDFGLSKN-LAH-EVHTSTFCGTTEYLAPEVVN---HQP-YTYSVDWWALGV
.  |....|.||| ||. |||..|.|.|||||||||.|    .|||||||||..|   .. .  | |||.| ||.|||...   .|  .. ..||| |||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LTYELLFGTTPFAH---QNRAKMFRNILDNE--PQFP--PNFNQEAIDFIKAMLTKDPLKRPT-----FEQIKQMKFF
| ||.|.| .||..   .||.. ...|. ..  . .|  ..  ||| |.|..||..|| ||..      |.||| ..|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 86485.m00553.AA S_TKc 109-360 37 1.2e-107 364.9 SMART 1-231 (231) Show / Hide 
Range on Protein: 109-360
Range on HMM: 1-231/231
Sequence Identity: 37% (101 aa)

FRVLKVIGRGFYGKVTLCEHIATKEIVAIKSIHKSRLIQQNKVTTVISERNILAKAQHPFIVNLKFAFQSPSKFYLGLEYVPG--GELFFHMQRYGN---
...|..||.| .||| .| |. |..||||| |.           ....|..|| | .||.||.|. .||. ...|. .||..|  |.|| .....|    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---IRLDDCKIYIAEILLALNHLHSLGVIYRDLKPENILLDANGHIKLTDFGLSKNLAHEVHTSTFCGTTEYLAPEVVNHQPYTY-SVDWWALGVLTYEL
   .   ... |...|..||...||.|.|.|||||||||||   |||..||||.. |      .||||| .|.||||.   .|.. ..|||..|.. ||.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LFGTTPFAHQNRAKMFRNILDNEPQFPPNFNQEAIDFIKAMLTKDPLKRPTFEQIKQ-------MKFF
| | .||   . ..||..|.           .||.|||. .|.||| ||||  .. |       . .|
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 86485.m00553.AA RSK-Unclassified 109-360 38 8.99999999999e-101 317.3 In-house 1-283 (283) Show / Hide 
Range on Protein: 109-360
Range on HMM: 1-283/283
Sequence Identity: 38% (108 aa)

FRVLKVIGRGFYGKVTLCEHIATKEIVAIKSIHKSRLIQQNKVTTVISERNILAKAQHPFIVNLKFAFQSPSKFYLGLEYVPGGELFFHMQ--RYGNIRL
| . . ||.|  ||| | .   |. | |.|  ||...|..||.  |. |.||.|  .||||| | ..||.  . || .|| .||..| |.|  .   .  
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

DDCKIYIAEILLALNHLHSLGVIYRDLKPENILLDANGHIKLTDFGLSKNL----------------------AHEVHTSTFCGTTEYLAPEVVNHQPYT
|| ..|..|. .|| .|| ...|||||||.||.|.  ||..||||.||.                         |   |  |||| ||||||..     |
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHT

YSVDWWALGVLTYELLFGTTPFAHQNRAKMFRNILDNEPQFP--PNFNQEAIDFIKAMLTKDPLKR----PT-FEQIKQMKFF
  |||| ||.. ||.||| .|.   |.  .| ||. |. .||      ... | ||..|.. | ||        . ||.  ||
KAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF
Kinase 86485.m00553.AA PKA 109-360 40 4.9e-98 332.01 In-house 1-263 (263) Show / Hide 
Range on Protein: 109-360
Range on HMM: 1-263/263
Sequence Identity: 40% (108 aa)

FRVLKVIGRGFYGKVTLCEHIATKEIVAIKSIHKSRLIQQNKVTTVISERNILAKAQHPFIVN-LKFAFQSPSKFYLGLEYVPGGELFFHMQRYGNIRLD
|  ....|.| .|.| || |  .....|.| . |.. .. . |  |..|.|||   .|||||. ... || ... |. .|||||||.| .... |    .
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

DCKIYIA-EILLALNHLHSLGVIYRDLKPENILLDANGHIKLTDFGLSKNLAHEVHTSTFCGTTEYLAPEVVNHQ-PYTYSVDWWALGVLTYELLFGTTP
. |.|.| .| |||  |||.  |||||||||||.| |||||.|||| .|..     |.| ||| ||||||...   ..  ||||||||.| ||.|.| .|
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPP

FAHQ--NRAKMFRNILDNEPQFPPNFNQEA---IDFIKAMLTKDPLKRP---TF--EQIKQMKFF
|     . ..... |.. . .||..|.. |    |.||  |..|. ||     .  ..||  |.|
FYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 86485.m00553.AA Pkinase 109-360 35 5e-98 336.78 Pfam 1-293 (293) Show / Hide 
Range on Protein: 109-360
Range on HMM: 1-293/293
Sequence Identity: 35% (106 aa)

FRVLKVIGRGFYGKVTLCEHIATKEIVAIKSIHKSRLIQQNKVTTVI-SERNILAKAQHPFIVNLKFAFQSPSKFYLGLEYVPGG----ELFFHMQ--RY
......||.| .|.| .| |. | .|||.| | |..   . ..| .  ||  |... .||.|| |. .|..... |. .||..||    .|| ...  |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GNI--RLDDCKIYIAEILLALNHLHSLGVIYRDLKPENILLDANGHI----KLTDFGLSKN--LAHEVHTSTFCGTTEYLAPEVVN-HQPYTYSVDWWAL
|..    ..|| |. .|| .|...|| |.|.|||||||||.| ||||    |..||||.|   . . . ..||||| .|.||||.. .|.|...||.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVLTYELLFGTTPFAHQ------NRAKMFRNILDNEPQFPPNFN---------------------QEAIDFIKAMLTKDPLKRPTFEQIKQMKFF
|.. ||.|.| .|| ..      .  .|...|.. .. |.                         .|..|||| .|.||| ||||.|||.| ..|
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 86485.m00553.AA PKC 109-360 41 4.2e-97 315.29 In-house 1-262 (262) Show / Hide 
Range on Protein: 109-360
Range on HMM: 1-262/262
Sequence Identity: 41% (109 aa)

FRVLKVIGRGFYGKVTLCEHIATKEIVAIKSIHKSRLIQQNKVTTVISERNILAKA-QHPFIVNLKFAFQSPSKFYLGLEYVPGGELFFHMQRYGNIRLD
|. |||.|.| .||| | |.  |.|. ||| . |   ||   |  .  |. .|| | .||| ..|   ||.... .  .||| || | ||.|...   . 
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

DCKIYIAEILLALNHLHSLGVIYRDLKPENILLDANGHIKLTDFGLSK-NLAHEVHTSTFCGTTEYLAPEVVNHQPYTYSVDWWALGVLTYELLFGTTPF
  . | |||..||. ||. |.|||||| .|.|||. ||||..|||..| |.  .. ||||||| .|.|||..  |.|. ||||||.||| ||.. |  ||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

AHQNRAKMFRNILDNEPQFPPNFNQEAIDFIKAMLTKDPLKRPTF--------EQIKQMKFF
  ..   .|..|.. .| .|  . .|| . .|...||.| ||           . |..  ||
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase 86485.m00553.AA Ciliate-E2 109-360 25 5.5e-91 308.58 In-house 1-365 (365) Show / Hide 
Range on Protein: 109-360
Range on HMM: 1-365/365
Sequence Identity: 25% (97 aa)

FRVLKVIGRGFYGKVTLCEHIATKE-----------------------IVAIKSIHKSRLIQQNKVTTVI----------SERNILAKAQHPFIVNLKFA
. ..|.||.| .|.| .|... ...                       |.|.|...|. ..|....  ..           |.||| . .||.|.... .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--SPSKFYLGLEYVPGGELFFHMQ------------RYGNIRLDDCKIYIAEILL---------------ALNHLHSLG-VIYRDLKPENILLDANGH
||  . ...|| .||. ||.|| ...              ... .  .| ....||                ||..||| . .|.||.||||||.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

IKLTDFGLSK---------------NLAHEVH------------------TSTFCGTTEYLAPEVVNHQP---------YTYSVDWWALGVLTYELLFGT
||..||||||               ..  . .                  . |.||| .|.|||..| ..         |.|..|.|.|||. ||.||| 
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

TPFAHQNRAKMFRNILDNEPQFPPN------------------FNQEAIDFIKA----MLTKDPLKRPT-FEQIKQMKFF
.||        ...|.... .||..                    ||..|.||     || ||| ||.| .|||.. ..|
PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 86485.m00553.AA Ciliate-E2-Unclassified 109-360 29 7.6e-91 308.12 In-house 1-352 (352) Show / Hide 
Range on Protein: 109-360
Range on HMM: 1-352/352
Sequence Identity: 29% (104 aa)

FRVLKVIGRGFYGKVTLCEHIATKEIVAIKSIHKSRLIQQNKVTTV---------ISERN-------------ILAKAQHPFIVNLKFAFQSPSKFYLGL
....|.||.| .||| .|.|. .|.. |.| ..|.. . |... ..         . ...             ||   .|||||.. ..||.  ..|. .
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYVPGGELFFHMQRYGN-----------------IRLDDCK-----IYIAEILLALNHLHSLG-VIYRDLKPENILLDANG---HIKLTDFGLSKNLA--
||..||.|..... ...                 .    .|      |.|.||..|..||. . .|.||.||||||.| ||   .||..|||.||..   
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

--------------HEVHTSTFCGTTEYL----APEVVNHQPYT----YSVDWWALGVLTYELLFGTTPFAHQNRAK----------------MFRNILD
               . ...||||| .|.    ||||   | |     |..|.|.|||. ||.|||. ||  .|. .                ...||..
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

NEPQFPP--------NFNQEAIDFIK----AMLTKDPLKRPTFEQIKQMKFF
...|||.        . ..||.|||.     || |.| ||.|||||..  .|
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 86485.m00553.AA TyrKc 109-360 22 8.9e-21 76.26 SMART 1-280 (280) Show / Hide 
Range on Protein: 109-360
Range on HMM: 1-280/280
Sequence Identity: 22% (66 aa)

FRVLKVIGRGFYGKVTLCEHIATKEIVAIKSIHKSRLIQQNKVTTVISERNILAKA--QHPFIVNLKFAFQSP-------SKFYLGLEYVPGGELFFHMQ
 . .|..|.|..|.| ... .   . ||.|.....       .   ..| .|. |   .|| ||.|  .  ..          .. .||.|.| |  . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RYGN-IRLDDCKIYIAEILLALNHLHSLGVIYRDLKPENILLDANGHIKLTDFGLSKNLAHE--------VHTSTF--CGTT----EYLAPEVVNHQPYT
.... . ..|   .   |    ..||| ..| |||   |.|...|...| .|||||... ..        . ...   .| |      .|||. |.  .|
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

YSVDWWALGVLTYELL-FGTTPFAH-----QNRAKMFRNILDN-EPQFPPN--------FNQEAIDFIKAMLTKDPLKRPTFEQIKQMKFF
   | |. ||. .|.. .| .|         . . ..... .   .  |||          .|  . .|     || .||||..|   ..|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 86485.m00553.AA S_TK_X 361-421 25 1.2e-10 42.62 SMART 1-79 (79) Show / Hide 
Range on Protein: 361-421
Range on HMM: 1-79/79
Sequence Identity: 25% (20 aa)

QNLNWDDVLQ--KKIQPKFVPASD----NSNEANNFDPEFTS----EQAADSYVMPVFGSAE--------KLAGFSYVD
 ...||....  |.|.| |.|       .   ..|||||||.    .. .|. ...  .  |        . .||.|| 
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 86485.m00553.AA Pkinase_Tyr 109-172 25 4e-06 21.49 Pfam 1-69 (270) Show / Hide 
Range on Protein: 109-172
Range on HMM: 1-69/270
Sequence Identity: 25% (18 aa)

FRVLKVIGRGFYGKVTLCEHI----ATKEIVAIKSIHKSRLIQQN-KVTTVISERNILAKA-QHPFIVNL
 . .|..|.| .|.| ...       ||  ||.|.. |    ... .    ..| .|. .  .|| ||.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRL
Kinase 86485.m00553.AA Pkinase_Tyr 237-300 27 5.7e-05 17.45 Pfam 141-208 (270) Show / Hide 
Range on Protein: 237-300
Range on HMM: 141-208/270
Sequence Identity: 27% (19 aa)

NILLDANGHIKLTDFGLSKNL----AH-EVHTSTFCGTTEYLAPEVVNHQPYTYSVDWWALGVLTYELL
|.|.. |...| .||||.. .        .....       .|||. |.  .|   | |. ||| .|..
NCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTKSDVWSFGVLMWEIF
Kinase 86485.m00553.AA Pkinase_Tyr 343-359 41 0.753538 3.5 Pfam 255-270 (270) Show / Hide 
Range on Protein: 343-359
Range on HMM: 255-270/270
Sequence Identity: 41% (7 aa)

KDPLKRPTFEQIKQMKF
.|| .||||..| . ..
YDPEDRPTFSEI-HEQL