Gene 88645.m00153 (T.vaginalis)

88645.m00153

Species: T.vaginalis
Alias: 88645.m00153, TvagK0304
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
88645.m00153.AA Protein None 962 None Fasta, JSON
88645.m00153.kin_dom Protein Kinase Domain None 255 None Fasta, JSON

Protein domain

Protein domains of 88645.m00153.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 88645.m00153.AA S_TKc 120-374 25 1.5e-60 208.36 SMART 1-231 (231) Show / Hide 
Range on Protein: 120-374
Range on HMM: 1-231/231
Sequence Identity: 25% (69 aa)

FTFQEIIGHGGFGEIWLANDLRTGKIVAIKELFAEKLVGRNLTNFVREIVTMGKCHNRFVIPFIGFTVEKPYCIITEYMPY--GSLHNYLRQERK-THKR
... ..||.|.||. ... . .||.|||||..           .. |||  . | |  ... .... ... .....||..   |.|. |... ..   ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

IFSGTHLTMIAIGLIIAIRYIHVQKIIHRDVKAANVLLDNHYLPKLCDFGISRFFNRKAMTVGIGTASHMAPELMSTSKYDI-KADVFAFGCTLYEMVEK
 |.  |   ..  .. |. |.| ..|||||.| .|.|||.    |.||||..|..     |  .||   ||||..   .|.  |.|. ..||.||||.  
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCG

KNPFAGYPSKEVIKNHKKGIRPKFYNQEEPDCLLCLIMKCWEQNPNDRPLPIEIFN--------DFA
. ||     ....|. .            .. .. .|.||.. .|..||   |...         . 
YPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 88645.m00153.AA TKL 126-373 22 1.1e-59 204.61 In-house 1-364 (364) Show / Hide 
Range on Protein: 126-373
Range on HMM: 1-364/364
Sequence Identity: 22% (83 aa)

IGHGGFGEIWLANDLR--------TGKIVAIKELFAEKLVGRNL-------------------------TNFVREIVTMGKCHNRFVIPFIGFTVEKP--
|| |||||.. ..           ||| ||.| .  .    ...                           ...||. | ...   ...|.|.  . |  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YCIITEYMPYGSLHNYLRQERKTHKRIFSGTHLTM-IAIGLIIAIRYIHVQK--------IIHRDVKAANVLLDNHYL----------
            .||..||.| |||..||              |... .|..   .. | | ..        ||||| | .|.|.|...           
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPN

----PKLCDFGISRFF---------------------NRKAMTVGIGTASHMAPELMSTS----------------KYDIKADVFAFGCTLYEMVEKKNP
    .|.||||.|||.                     |||.    .||  .||||..  .                .|. |.||..||  |.|..  . |
ADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRP

FAGYPS-------------KEVIKNHKKGIRPKFYN-----QEEPDC---LLCLIMKCWEQNPNDRPLPIEIFNDF
...||.             . |... ..  .|   .     . .|||   .  |...||...|..||   ||   .
YYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Pkinase 88645.m00153.AA Pkinase 120-373 23 4.8e-55 193.97 Pfam 1-293 (293) Show / Hide 
Range on Protein: 120-373
Range on HMM: 1-293/293
Sequence Identity: 23% (70 aa)

FTFQEIIGHGGFGEIWLANDLRTGKIVAIKELFAEKLVGRNLTNFVR--EIVTMGKCHNRFVIPFIGFTV-EKPYCIITEYMPYG----SLHNYLRQERK
... ..|| |.||. ... .  ||||||.|..  ..     . . .|  ||  | ...  ... ....   .. .....||.. |    .|. |..   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--W

THKRI-FSGTHLTMIAIGLIIAIRYIHVQKIIHRDVKAANVLLDNHYLP----KLCDFGISR---FFNRKAMTVGIGTASHMAPELMS-TSKYDIKADVF
 |... ||  .. ...  .. .. |.| ..|||||.| .|.|.||.. .    |.||||...     |   ||.  ||   ||||.    ..|. |.|..
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

AFGCTLYEMVEKKNPFAGY----PSKEVIKNHKKGIRPKFYNQEE----------------------PDCLLCLIMKCWEQNPNDRPLPIEIFND--F
..||.||||. .. || |     .  . .. ...  .|..  ...                      .. .. .| .|....|..|| . .|...  |
SCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 88645.m00153.AA MLK 120-373 27 6.5e-48 164.28 In-house 1-291 (291) Show / Hide 
Range on Protein: 120-373
Range on HMM: 1-291/291
Sequence Identity: 27% (81 aa)

FTFQEIIGHGGFGEIWLANDLRTG---KIVAIKELFAEK----LVG---RNLTNFVREIVTMGKCHNR---FVIPFIGFTVEK-P-YCIITEYMPYGSLH
..|.|.||.|.||. |...   .    ||||.|. .|..      .   ...  ..|.   .  .|.     .|.| |   .  . .||..||...|||.
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRIL--SHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLY

NYLRQERKTHK---------RIFSGTHLTMIAIGLIIAIRYIHVQK---IIHRDVKAANVLLDN------HYLPKLCDFGISRFFNRK-A-MTVGIGTAS
|.|. .|.            |. .  |.  .|     .. | | ..   ||||| |  |.|.|.      |   | ||||.||..... . |.  .||. 
NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYA

HMAPELM---STSKYDIKADVFAFGCTLYEMVEKKNPFA-GYP-SKEVIKNHKKGIRPKFYNQEEPDCLLCLIMKCWEQNPNDRPLPIEIFNDF
 ||||       .||..|.||. .|  |.||. .. |.. .|  .   ...  .|.||   ..  |. .  |...||.|.|..||   .|   .
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPST-CPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 88645.m00153.AA STE 120-374 21 3.1e-46 159.92 In-house 1-359 (359) Show / Hide 
Range on Protein: 120-374
Range on HMM: 1-359/359
Sequence Identity: 21% (77 aa)

FTFQEIIGHGGFGEIWLANDLR---------------TGKIVAIKEL-FAEKLV--------------GRNLTNFVREIVTMGKCH--NRFVIPFIGFTV
....|.||.|.||.  .| .                 ||.|.|||.. . ..                  .. .. .|| .| ||.    ... ..|  .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EKP--------YCIITEYMPYGSLHNYLRQERKTHK---------RIFSGTHLTMIAIGLIIA-IRYIHVQKIIHRDVKAANVLLDNHYLPKLCDFGISR
 .          .|. |||..|||   ...  .. |           |. . .  |.  .. .   |.| ..|||||.|.||.||      ||||||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

FFNR-------------------KAMTVGIGTASHMAPELMST------SKYDIKADVFAFGCTLYEMVEKKNPFAG-YPSKEVIKNHKK----------
 ..                    |  |. .||  .|||| ..       ..||.|.|.  .|||. ||.. | |..  .| .      ..          
QLTDSMANIQSNNIIDCIETMQQKRNTF-VGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

----GIRPKFYNQEEP------------------DCLLCLIMKCWEQNPNDRPLPIEIFN---DFA
    |  |.. .  ..                  ...   | || . .||.|| . .  .    | 
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 88645.m00153.AA TK 120-373 14 1.7e-43 143.21 In-house 1-486 (486) Show / Hide 
Range on Protein: 120-373
Range on HMM: 1-486/486
Sequence Identity: 14% (69 aa)

FTFQEIIGHGGFG---EIWLA------------------------NDLRTGK-IVAIKELF--AEKLVGRNLT-------------NFVREIVTMG--KC
 |. . .|.| ||   |....                        |. . ||  ||.| |   ..    . .              ....|.  |   ..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

HNRFVIPFIG-FTVE------------KPYCIITEYMPYGS----LHNYLRQERKTHKR-----------------------------------------
|   .. ..|  | .            .|..|..||||.|.    |..|||. |.. .                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------IFSGTHLTMIAIGLIIAIRYIHVQ------KIIHRDVKAANVLLDNHYL-----------PKLCDFGISR
                              ...  .|  ..  .  . .|.| .      ...|||. | |.|.....             |..||| ||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

F----FNRKAMTVGIGTASH--------------------------------MAPELMS---------TSKYDIKADVFAFGCTLYEMVE--KKNPFAGY
       |.    .  ....                                |||| .          . |. .| ||..||....|..   .. .  | 
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

PS---------KEVIKNHKKG--------------IRPKFYNQEEP-------------DCLLCLIMKCWEQNPNDRPLPIEIFNDF
..         .||... ..|               |..   .  .             . .  |...||. .|.|||   .. . .
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 88645.m00153.AA Ciliate-E2 120-371 17 4.7e-43 145.64 In-house 1-361 (365) Show / Hide 
Range on Protein: 120-371
Range on HMM: 1-361/365
Sequence Identity: 17% (66 aa)

FTFQEIIGHGGFGEIWLANDLRTGKIVAIK-----------------ELFAEKLVGRNLTNFVREIVTMG-----------------KCHNRFVIPFIGF
. |...|| |.|| ...... ...| .|||                  ..| | .  |  ...  .  .                  .  . ..| .. .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

TV---EKPYCIITEYMPYGSLHNYLRQERK--------------THKRIFSGTHLT-------MIAIGLIIAIRYIHVQK-IIHRDVKAANVLLDNHYLP
     .. . ...||  .|.|  |... .|               . . ..   |        ...  .| |..|.| .. ||||| |  |.|.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLCDFGISRFFN------------RKAMTVG----------------------IGTASHMAPELMSTSK---------YDIKADVFAFGCTLYEMVEKKN
|..|||.|....             . |  .                      .||.  ||||  .  |         || |.|....|..||||. .| 
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFAGYPSKEVIKNHKKGIRPKFYN---------------QEEPDCLLCLIMK----CWEQNPNDRPL-PIEIFN
||        ...... |.  ...               .. ..    || |    . . .|. |.  . .|.|
PF-------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN
Kinase 88645.m00153.AA Ciliate-E2-Unclassified 120-371 19 7e-43 146.58 In-house 1-348 (352) Show / Hide 
Range on Protein: 120-371
Range on HMM: 1-348/352
Sequence Identity: 19% (68 aa)

FTFQEIIGHGGFGEIWLANDLRTGKIVAIKELF-----AEKLVGRNLTNFVREIVTMGKC------------------HNRFVIPFIGFTV--EKPYCII
......||.||||..... .  .... |.|..      . |.. ..  ....|. .| .                   |.  .|    ..   ..  .|.
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

TEYMPYGSLHNYLRQ------------ERKTHKRIFSGTHLT-----MIAIGLIIAIRYIHVQK-IIHRDVKAANVLLDNHY---LPKLCDFGISRF---
.||...|.|..|...            ... ...||.  .        ..  .. .. |.| .. ||||| |  |.|.||      .|..|||||..   
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

-------------FNRKAMTVGI-GTASHM----APELMSTSKYD----IKADVFAFGCTLYEMVEKKNPFAGYPSKE----------------VIKNHK
             .... |.  . || . |    |||..   .||    .|.|....|. ||||.  . || .. ...                ...| |
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

KG-IRPKFYNQ-----EEPDCLLCLIM----KCWEQNPNDRPLPIEIFN
.. |  . ...       ...   .|     |. . ||| |. . .|.|
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILN
Kinase 88645.m00153.AA HH498 120-373 27 3e-40 125.03 In-house 1-284 (284) Show / Hide 
Range on Protein: 120-373
Range on HMM: 1-284/284
Sequence Identity: 27% (80 aa)

FTFQEIIGHGGFGEIWLANDLRTGKIVAIKELFAEKLVGRNL------TNFVREIVTMGKCHNRFVIPFIGFTVEKP--YCIITEYMPYGSLHNYL----
. |.|.|| | ||.. .    | .||||.|   |..              |.||.. | .  .  |. |.. ... |    |.|.|   |||   |    
IEFHEKIGSGSFGKVYKGE-WR-NKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYACCDDPSQFAIVTQYCDNGSLFSILNTIP

---------RQERKTHKRIFSGTHLTMIAIGLIIAIRYIHV---QKIIHRDVKAANVLLDNHYLPKLCDFGISRFFNR---KAMTVGIGTASHMAPELMS
           . |   || .      |..      .| |    . |||||    |.|..     .  |||.||| .    . ||  .|    ||||  |
IGGAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFS

-TSKYDIKADVFAFGCTLYEMVEKKNPFAGY-PSKEVIKNHKKGIRPKFYNQ---EEPDCLLCLIMKCWEQNPNDRPLPIEIFNDF
   ||.||.||| ..  ..||   . ||. | |     .   . |||   ..     |   . ||. ||...|..||   .|    
QCQKYSIKVDVFSYAMCIWEMHTREVPFHHYKPAAAAAEMAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL
Kinase 88645.m00153.AA TKL-Unique 122-373 27 7.6e-40 138.23 In-house 1-290 (290) Show / Hide 
Range on Protein: 122-373
Range on HMM: 1-290/290
Sequence Identity: 27% (81 aa)

FQEIIGHGGFGEIWLANDLRTGKIVAIKELFA-EKLVGRNLTNFVREIVTMGKCH-NRFVIPFIGFTV----EKP-YCIITEYMPYGSLHNYLRQ-----
| . || ||.|..  .     |..|||| ..  |..  . . .| .|. .| | |   ..  ..|...      | .||..||.| |||...| |     
FWNKIGEGGYGQVYKG--KWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

---ERKTHKRIFSGTHLTMIAIGLIIAIRYIHVQK--IIHRDVKAANVLLDNH-----YLPKLCDFGISRFFNRK-AMTVG----------IGTASHMAP
   ....    ..      .||    .  |.|  .  ||||| |  |.|.||.     .  |.||||.|.| ..  .||..          .|..  |||
NNNNNNCK---LNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAP

ELMST--SKYDIKADVFAFGCTLYEMVEKKN------PFAGYPSKEVI-KNHK--KGIRPKFYNQEEPDCLLCLIMKCWEQNPNDRPLPIEIFNDF
|...   ..|..|.||..||  |.|... |       |. |. ..... . |.  .. ||.  |  ... .  || .|| ..| .||  .|| .  
EVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKE-YRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 88645.m00153.AA Dicty5 143-319 36 3.2e-38 129.15 In-house 22-203 (260) Show / Hide 
Range on Protein: 143-319
Range on HMM: 22-203/260
Sequence Identity: 36% (67 aa)

GKIVAIKELFAEKLVGRNLTNFVREIVTMGKCH--NRFVIPFIG-FTVEKPY-CIITEYMPYGSLHNYLRQERK-THKRIFSGTHLTMIAIGLIIAIRYI
|. ||||..  |  .. ..  | ||.  |         .| . |  . .. |  ..|||   ||| |||.. || | . |  .. | | ||.   ..|..
GMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQPIAYFQQLHM-AIDIAQSMRHL

HVQKIIHRDVKAANVLLDNHYLPKLCDFGISR-FFNRKAMTVGIGTASHMAPELMSTSKYDIKADVFAFGCTLYEMVEKKNPF
|   |||||.|  |.|.   .  |. |||.||   ||. ||. .||   ||.||     |. |.||..||  |.||  .| |.
HSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEMFTRKEPY
Kinase 88645.m00153.AA TyrKc 120-373 25 6e-37 129.99 SMART 1-280 (280) Show / Hide 
Range on Protein: 120-373
Range on HMM: 1-280/280
Sequence Identity: 25% (75 aa)

FTFQEIIGHGGFGEIWLANDLRTGKIVAIKELFAEKLVGRNLTNFVREIVTMGKC--HNRFVIPFIGFTVE--------KPYCIITEYMPYGSLHNYLRQ
 |. ...|.| |||....  ..    ||.| | ...     .  | ||.  | |   |.  .. ..|  ..        .|..|..||||.|.|..||| 
ITLGKKLGEGAFGEVYKG-TWK--IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

ERKTHKRIFSGTHLTMIAIGLIIAIRYIHVQKIIHRDVKAANVLLDNHYLPKLCDFGISRFFNRK--------AMTVGIGTASH-------MAPELMSTS
 |..    ..  .|  ...      .|.| ...||||  | |.|... .  | .||| ||.   .          ..  .  ..       |||| . ..
HRPK----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

KYDIKADVFAFGCTLYEMVEK-KNPFAG-----YPSKEVIKNHKKGIRPKFYNQ-------EEPDCLLCLIMKCWEQNPNDRPLPIEIFNDF
|. .| ||..|| ...|.    . |  |      . .|||.. |.| |..           . || .  .. .||. .|.|||   ||  .|
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 88645.m00153.AA ULK 120-338 20 2.2e-36 126.64 In-house 1-280 (324) Show / Hide 
Range on Protein: 120-338
Range on HMM: 1-280/324
Sequence Identity: 20% (58 aa)

FTFQEIIGHGGFG-EIWLANDLRT---GKIVAIKELFAEKLVGRNLT--------NFVREIVTMGKCH------NRFVIPFIGFTVEK---PYCIITEYM
.   ...|.| ||     . . .|   ...||.|     |.   ..         .. .|| .| | .      .  .. .. .. ..    ..||.|| 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNH-HIVKLYDWFETSNHNNIYIIMEYC

PYGSLHNYLRQERK---T-HKRIFSGTHLTMIAIGLIIAIRYIHVQKIIHRDVKAANVLLDN------------HYLPKLCDFGISRFFNRKAM--TVGI
. | | .|. . .|   |  |...|      . . .. . ...| ..||||| | .| |. |            ..  |..||| .....   |  ..  
NGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

---------GTASHMAPELMS----TSKYD-IKADVFAFGCTLYEMVEKKNPFAGYPSKEVI----KNHKKG------IRPK
         ||   |||.. .      .|. .|.|.. .|| .|||.  | || ..   . .    |  ..|      |. .
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQ
Kinase 88645.m00153.AA Pkinase_Tyr 120-269 29 9.6e-29 97.97 Pfam 1-159 (270) Show / Hide 
Range on Protein: 120-269
Range on HMM: 1-159/270
Sequence Identity: 29% (47 aa)

FTFQEIIGHGGFGEIWLANDL----RTGKIVAIKELFAEKLVGRN--LTNFVREIVTMGKC-HNRFVIPFIGFTV--EKP--YCIITEYMPYGSLHNYLR
 || . .|.| |||....        |.  ||.| |  |.   ..  .  | ||. .| .  |.  .. ..|  .  ..|  ..|..||||.|.|..|||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

QERKTHKRIFSGTHLTMIAIGLIIAIRYIHVQKIIHRDVKAANVLLDNHYLPKLCDFGISR
. | . |. ..  .|  ...    .  | . ...||||. | |.|...    | |||| .|
KHR-EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR
Kinase 88645.m00153.AA Pkinase_Tyr 286-364 31 3.1e-12 42.04 Pfam 181-261 (270) Show / Hide 
Range on Protein: 286-364
Range on HMM: 181-261/270
Sequence Identity: 31% (26 aa)

MAPELMSTSKYDIKADVFAFGCTLYEMVE-KKNP-FAGYPSKEVIKNH-KKGIRPKFYNQEEPDCLLCLIMKCWEQNPNDRP
|||| ....|. .| || .|| ...|..   . | ..| .  ||..   ..| | .   .  || .  |...||...|.|||
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPC-PENCPDEIYDLMKQCWHYDPEDRP
Kinase 88645.m00153.AA Dicty5 351-377 48 0.000391 10.12 In-house 234-260 (260) Show / Hide 
Range on Protein: 351-377
Range on HMM: 234-260/260
Sequence Identity: 48% (13 aa)

LIMKCWEQNPNDRPLPIEIFNDFASGR
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LIKKCWQQKPHNRPSFKEICKYFESII