Gene 95725.m00240 (T.vaginalis)

95725.m00240

Species: T.vaginalis
Alias: TvagK0435, 95725.m00240
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
95725.m00240.AA Protein None 453 None Fasta, JSON
95725.m00240.kin_dom Protein Kinase Domain None 256 None Fasta, JSON

Protein domain

Protein domains of 95725.m00240.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH 95725.m00240.AA PH 3-98 34 3.2e-20 74.42 SMART 1-82 (82) Show / Hide 
Range on Protein: 3-98
Range on HMM: 1-82/82
Sequence Identity: 34% (33 aa)

VYKTGWATKQGGMIKTWKKRYFVLTDDWLVYYDKPDGNEHGRIPLDPTVVVSPAPDCKKQPAYKIVTSGRTYYVVPETQAEVNEWVAVLTAAINNS
| | || .|..    .||||.|||..| |.||...     |.|||.   |.  .       . .|.. .||||.  |.. | .||.. . .||.|.
VIKEGWLYKKS--K-RWKKRWFVLFNDCLYYYKDK--KPKGSIPLSDCTVRE-P-------CFEIHH-DRTYYFQCESEEEMQEWMQAIQKAIHNN
PH 95725.m00240.AA PH 3-96 37 5.7e-17 63.84 Pfam 1-92 (92) Show / Hide 
Range on Protein: 3-96
Range on HMM: 1-92/92
Sequence Identity: 37% (36 aa)

VYKTGWATKQGGMIKTWKKRYFVLTDDWLVYYDKPDGNEHGRIPLDPTVVVSPAPDCKKQPAYKIVTSGR-TYYVVPETQAEVNEWVAVLTAAIN
|.| || .|.|  .|.||||.|||... |.||.... .  | |||.    | ..|| |..   .|.| .| |||.  |.. | |.|.. . .|. 
VIKEGWLHKKG-KRKSWKKRWFVLFNNCLYYYKDDKYRPKGSIPLSDC-QVTKVPDNKRPHCFQIRT-DRRTYYFQAESEEEMNDWMQAIQSACR
Kinase 95725.m00240.AA AGC 127-382 34 7.1e-186 485.81 In-house 1-395 (395) Show / Hide 
Range on Protein: 127-382
Range on HMM: 1-395/395
Sequence Identity: 34% (136 aa)

FTILGVLGRGTYGKVQLVKEK------ETGKLFALKTMSKRL---LAESDQVEQTITE------------RNVLLTTK----------HPFLVC-AHYTF
| .| |.|.|..||| ||..|       |||..|.| ..|.    . . ..||.|.||            ||.| . .          |||.|   ||.|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTDAK--IFMVLDYVP---------GG-ELFGRLK---EESLFAESRVRLYAAE-------ICLGLGYLHK-LGFIYRD-LKPENILVDQDGHLKITDFG
|.. .  ...|..|.|         || ||| .|.    |  | |.|.| ||||       |.|.| |||. .|.|.|| ||||||| |.|||.|.||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LAKNTDMG----------------------------------------------------TTSTFCG--TPEYIAPEMLQRLPYTKAVDWWS--YGIIIY
|.|   ..                                                    .|.||||  ||||.|||.|    |.||.||||  .|...|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMLTGLPPFYDEN----------TNQMYRSIL------RDDVKYP----------SHVSHDARSLINQLLNRNPEARLGSGPSD-----YEEIKAHPFF
|||||.||||..|           ..|. .|.       ..||.|          ...| .|..||..||...|| |||.|..|     .||||.||.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 95725.m00240.AA Akt 127-382 50 6.1e-154 495.55 In-house 1-264 (264) Show / Hide 
Range on Protein: 127-382
Range on HMM: 1-264/264
Sequence Identity: 50% (134 aa)

FTILGVLGRGTYGKVQLVKEKETGKLF-ALKTMSKRLLAESDQVEQTITERNVLLTTKHPFLVCAHYTFQTDAKIFMVLDYVPGGELFGRLKEESLFAES
|..| |||.|..||| |||.| |.|.. |.|  .|. . . .|||.|.||||.| ...|||.|  || |||  |...|.||..|||||  |. .  | |.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

RVRLYAAEICLGLGYLHKLGFIYRD-LKPENILVDQDGHLKITDFGLAK-N--TDMGTTSTFCGTPEYIAPEMLQRLPYTKAVDWWS-YGIIIYEMLTGL
| | |.||| |....||. . |||| |||||||.|.|||...|||||.| |  .|  .| ||||||||.|||.|.   .|||||||.  |...|||..|.
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

PPFYDENTNQMYRSILRDDVKYP--SHVSHDARSLINQLLNRNPEARLGSGPSDYEEIKAHPFF
||||...  ||.  |.  .||.|  . .| ....||..|||..|. |||.||.| .|||.||.|
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 95725.m00240.AA SGK 127-382 44 8.3e-139 431.52 In-house 1-283 (283) Show / Hide 
Range on Protein: 127-382
Range on HMM: 1-283/283
Sequence Identity: 44% (126 aa)

FTILGVLGRGTYGKVQLVKEKET------------------GKLFALKTMSKRLLA-------ESDQVEQTITER-NVLLTTKHPFLVCAHYTFQTDAKI
| .| |.| | .||| .|| |..                  .|..|.|  .|              ..  . .|| ..|   ||||.|  || |||. | 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

FMVLDYVPGGELFGRLKEESLFAESRVRLYAAEICLGLGYLHKLGFIYRDLKPENILVDQDGHLKITDFGLAK--NTDMGTTSTFCGTPEYIAPEMLQRL
..|.||| |||.|  |. |  | |.|.| ||||| . |.|||..  ||||||||||| | .||...|||||.|    .  ||.|||||||| |||.|.  
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

PYTKAVDWWSYGIIIYEMLTGLPPFYDENTNQMYRSILRDDVKYPSHVSHDARSLINQLLNRNPEARLGSGPSDYEEIKAHPFF
|. ..||||. |.. |||..||||||. |..|||  |.. . . |  .| ||..||..||...|. |||.   | .||| ||||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTK-RDFMEIKNHPFF
Kinase 95725.m00240.AA AktR 127-382 48 2.3e-129 436.1 In-house 1-268 (268) Show / Hide 
Range on Protein: 127-382
Range on HMM: 1-268/268
Sequence Identity: 48% (129 aa)

FTILGVLGRGTYGKVQLVKEK-ETGKLFALKTMSKRLLAESDQVEQTITERNVLL-TTKHPFLVCAHYTFQTDAKIFMVLDYVPGGELFGRLKEESLFAE
|... .||.|..||| ||..| ...|..|.|  .|  . |  | ..||||||..    .|||.|  ||.|||. |.| ...|.||||||  || .  | |
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

SRVRLYAAEICLGLGYLHKL-GFIYRDLKPENILVDQDGHLKITDFGLAK----NTDMGTTSTFCGTPEYIAPEMLQR-LPYTKAVDWWSYGIIIYEMLT
...| |.|.|.|.| |||.    ||||||||||| |.|||.|||||||.|    . .  .. .|||||||.||||...  ...|.||||. || ||||.|
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GLPPFYDENTNQMYRSILRDD---VKYPSHVSHDARSLIN-QLLNRNPEARLGSGPSDYEEIKAHPFF
|.||||..|.|||. .|.  .   ..||| .|  ...||. .||..||. |||.. .. |||| ||.|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 95725.m00240.AA PKA 127-382 45 2.2e-128 432.82 In-house 1-263 (263) Show / Hide 
Range on Protein: 127-382
Range on HMM: 1-263/263
Sequence Identity: 45% (119 aa)

FTILGVLGRGTYGKVQLVKEKETGKLFALKTMSKRLLAESDQVEQTITERNVLLTTKHPFLVC-AHYTFQTDAKIFMVLDYVPGGELFGRLKEESLFAES
| |. .||.|..|.|.|...|..|. .|.|...|.      ||| ...|.|.|. .||||.|    .|||.| ...||..||||||.| .|  .  | ..
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

RVRLYAA-EICLGLGYLHKLGFIYRDLKPENILVDQDGHLKITDFGLAKNTDMGTTSTFCGTPEYIAPEMLQRL-PYTKAVDWWSYGIIIYEMLTGLPPF
  ..||| .|.| | |||..  ||||||||||| |..||.|||||| ||..|   |.| ||||||.|||..|.  .. |.||||. ||.|||||.| |||
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD-RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPF

YDE--NTNQMYRSILRDDVKYPSHVSHDA---RSLINQLLNRNPEARLGSGPSDYEEIKAHPFF
||.  ...|.|. |.  ..|.|.|.. ||   ..||..||..... |.|.  .. . || |..|
YDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 95725.m00240.AA RSK 130-382 43 8.99999999999e-123 414.17 In-house 1-278 (278) Show / Hide 
Range on Protein: 130-382
Range on HMM: 1-278/278
Sequence Identity: 43% (120 aa)

LGVLGRGTYGKVQLVKEK---ETGKLFALKTMSKRLLAESDQ-VEQTITERNVLLTTK-HPFLVCAHYTFQTDAKIFMVLDYVPGGELFGRLKEESL---
| |||.| |||| |....    ||...| |  .|. .. ..  .. | ||||.|.... |||.|  ||.|||. |......|..||||| .|..|     
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FAESRVRLYAAEICLGLGYLHKLGFIYRDLKPENILVDQ---DGHLKITDFGLAKN--TD-MGTTSTFCGTPEYIAPEMLQ---RLP-YTKAVDWWSYGI
| |.... |.||| | . .||..|.|.||||||||| |.   .||.|.||||..|    |  . | |||.| ||.|||||    .   ..||.|||| |.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

IIYEMLTGLPPFYD---ENTNQMYRSILRDD--VKYP--SHVSHDARSLINQLLNRNPEARLGSGPSDYEEIKAHPFF
..|||||| |||.    .| ..  . |.. .  .. |  . .|..|..||...| |.|. |||.||.| ||||.||.|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 95725.m00240.AA RSK-Unclassified 127-382 40 1.1e-120 380.91 In-house 1-283 (283) Show / Hide 
Range on Protein: 127-382
Range on HMM: 1-283/283
Sequence Identity: 40% (115 aa)

FTILGVLGRGTYGKVQLVKEKETGKLFALKTMSKRLLAESDQVEQTITERNVLLTTKHPFLVCAHYTFQTDAKIFMVLDYVPGGELFGRLK--EESLFAE
|   . .|.|  ||| ||..|.| ...|.| ..|  .     .   .||.|.. ||.||| |   . |||  . .....| .||..|  |    |  |.|
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

SRVRLYAAEICLGLGYLHKLGFIYRDLKPENILVDQDGHLKITDFGLAKNT-----------------------DMGTTSTFCGTPEYIAPEMLQRLPYT
 .|| ||.|. . | ||||..||||||||.||. .|.|| . |||.| .                         .   |  |||| ||.||||..|   |
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHT

KAVDWWSYGIIIYEMLTGLPPFYDENTNQMYRSILRDDVKYP--SHVSHDARSLINQLLNRNPEARLGSGPSDYEEIKAHPFF
||||||  ||..|||| |.||.| .|.| ..  |.. .|| |  | .| ..|.||  ||.|||  |||..  | ..||.||||
KAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF
Kinase 95725.m00240.AA PKC 127-382 45 6.4e-114 370.69 In-house 1-262 (262) Show / Hide 
Range on Protein: 127-382
Range on HMM: 1-262/262
Sequence Identity: 45% (119 aa)

FTILGVLGRGTYGKVQLVKEKETGKLFALKTMSKRLLAESDQVEQTITERNVL-LTTKHPFLVCAHYTFQTDAKIFMVLDYVPGGELFGRLKEESLFAES
|. | |||.| .||| |.. |.| ...| | . | .  . | || | ||. || | .|||||.  | .|||  ..| |. || || |     .   | |.
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

RVRLYAAEICLGLGYLHKLGFIYRDLKPENILVDQDGHLKITDFGLAKN--TDMGTTSTFCGTPEYIAPEMLQRLPYTKAVDWWSYGIIIYEMLTGLPPF
. | |||||...| .||. | |||||| .|.|.|..|| ||.|||..|   ..  |||||||||.||||| ||  .|.|.||||..|.  |||. | .||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

YDENTNQMYRSILRDDVKYPSHVSHDARSLINQLLNRNPEARLGSGPSD---YEEIKAHPFF
  |.  .. .||. |.. || . | .| |.. .....||| |||..|..    ..|..||||
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase 95725.m00240.AA S_TKc 127-382 36 3.3e-107 363.4 SMART 1-231 (231) Show / Hide 
Range on Protein: 127-382
Range on HMM: 1-231/231
Sequence Identity: 36% (98 aa)

FTILGVLGRGTYGKVQLVKEKETGKLFALKTMSKRLLAESDQVEQTITERNVLLTTKHPFLVCAHYTFQTDAKIFMVLDYVPG--GELFGRLKEESL---
..|| ..|.|..||| ....|.||...|.| ..          |... |...|   .||..|  ...||.  ...||..|..|  |.|| ..|.      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FAESRVRLYAAEICLGLGYLHKLGFIYRDLKPENILVDQDGHLKITDFGLAKNTDMGTTSTFCGTPEYIAPEMLQRLPYTK-AVDWWSYGIIIYEML
   | | ..| |...||..| |.|..|.|.|||||||||.|.  |.||.|||||.       .||||||.|.|||.|   .|.| ..|||| |.|.||||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

TGLPPFYDENTNQMYRSILRDDVKYPSHVSHDARSLINQLLNRNPEARLGSGPSDY--EEIKAHPFF
.| |||.  . ..|.. |.          |..|...|...|...|| |..        ..||.||.|
CGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 95725.m00240.AA RSK 127-382 38 1e-101 344.22 In-house 1-271 (271) Show / Hide 
Range on Protein: 127-382
Range on HMM: 1-271/271
Sequence Identity: 38% (105 aa)

FTILGVLGRGTYGKVQLVKEK---ETGKLFALKTMSKRLLAESDQVEQTITERNVLLTTKHPFLVCAHYTFQTDAKIFMVLDYVPGGELFGRLKEESLFA
. .. ..|.|...|| ..| .    |....| |   |  .. .|.  .. .||..|    ||| |  || ||.  |..|..|   ||.||.||  .  | 
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFS

ESRVRLYAAEICLGLGYLHKLGFIYRDLKPENILVDQD----GHLKITDFGLAKNT--DMGTTSTFCGTPEYIAPEMLQRLPYTKAVDWWSYGIIIYEML
|. |. |.||| | . |||..| ..|||||||||.| .    ||.||.|||.||    . | . |||.| .|.|||.| |  ...|.||||.|.. ||||
EREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEML

TGLPPFYDENTNQMYRSILRDDVKY-------PSHVSHDARSLINQLLNRNPEARLGSGPSDYEEIKAHPFF
|| .||.  . . .   |.| ..         .. .|  | .|. ..| |.|. |||.|| . |.|| ||.|
TGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase 95725.m00240.AA p70 166-382 44 1.3e-97 330.63 In-house 69-299 (299) Show / Hide 
Range on Protein: 166-382
Range on HMM: 69-299/299
Sequence Identity: 44% (102 aa)

SDQVEQTITERNVLLTTKHPFLVCAHYTFQTDAKIFMVLDYVPGGELFGRLKEESLFAESRVRLYAAEICLGLGYLHKLGFIYRDLKPENILVDQDGHLK
| ..|.|  |||.| . ||||..  || |||. | . .|.| .|||||  |.... . |  .. |..|| . |..||..| |||||||||.. .| ||..
SKRLERTFAERNILEEVKHPFICDLHYAFQTNGKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVV

ITDFGLAKNTDMGTTS------------TFCGTPEYIAPEMLQRLPYTKAVDWWSYGIIIYEMLTGLPPFYDENTNQMYRSILRDD--VKYPSHVSHDAR
 ||||| |    . .             |||||.|| |||.| |  . .|||||| |. .| |||| |||  ||  .   .||.    .| |   .|..|
LTDFGLCKESIHDGAVDEEDPENVNATHTFCGTIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMR

SLINQLLNRNPEARLGSGPSDYEEIKAHPFF
 ||..|| |.| .|.|.||.| ..|..||||
DLIKKLLKRHPTQRWGAGPEDAADIQEHPFF
Kinase 95725.m00240.AA Pkinase 127-382 31 4.1e-95 327.08 Pfam 1-293 (293) Show / Hide 
Range on Protein: 127-382
Range on HMM: 1-293/293
Sequence Identity: 31% (93 aa)

FTILGVLGRGTYGKVQLVKEKETGKLFALKTMSKRLLAESDQVEQTI-TERNVLLTTKHPFLVCAHYTFQTDAKIFMVLDYVPGG----ELFGRLK--EE
..|....|.|..|.| . ..| |||..|.|...||   .. ... .  .|  ...  .||. |  ...|... .| ||..|..||    .|| ...  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

SLF--AESRVRLYAAEICLGLGYLHKLGFIYRDLKPENILVDQDGHL----KITDFGLAK---NTDMGTTSTFCGTPEYIAPEMLQ-RLPYTKAVDWWSY
  |   |  .. |. .|. || |.|. |.|.|||||||||.|..||.    ||.||||||   .   . ..||||||.|.||| .. . .|...||.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GIIIYEMLTGLPPFYDE------NTNQMYRSILRDDVKYPSHVS---------------------HDARSLINQLLNRNPEARLGSGPSDYEEIKAHPFF
|.|.||||.| |||...      . .||.. |.. ......  .                      .....|. .|...|. |..      |.|. ||.|
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQHPWF
Kinase 95725.m00240.AA TyrKc 127-376 19 1.2e-15 30.04 SMART 1-280 (280) Show / Hide 
Range on Protein: 127-376
Range on HMM: 1-280/280
Sequence Identity: 19% (56 aa)

FTILGVLGRGTYGKVQLVKEKETGKLFALKTMSKRLLAESDQVEQTITERNVLLTT--KHPFLVCAHYTFQTD-------AKIFMVLDYVPGGELFGRLK
 | . .||.| .|.| . . |       ..   | | ...  .|  . | ...     .|| .|. .    ..         ...|. |.|.| |  .|.
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

EESL-FAESRVRLYAAEICLGLGYLHKLGFIYRDLKPENILVDQDGHLKITDFGLAKNTDMG------TTSTFC----GTPE-----YIAPEMLQRLPYT
.    .  .    ..  |. |  |||. ..| |||   |.||. ... ||.||||... . .      .         |.         ||| ..   .|
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

KAVDWWSYGIIIYEMLT-GLPPFYD-----ENTNQMYRSILRDDVKYPSHV---------SHDARSLINQLLNRNPEARLGSGPSDYEEI
 . | ||.|. ..|..| | .| ..      .  .... . . .   . .          . .  ... |  ...|| |       .|..
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase 95725.m00240.AA Pkinase_Tyr 127-335 25 8.5e-14 47.35 Pfam 1-228 (270) Show / Hide 
Range on Protein: 127-335
Range on HMM: 1-228/270
Sequence Identity: 25% (58 aa)

FTILGVLGRGTYGKVQLVKEK----ETGKLFALKTMSKRLLAESDQ--VEQTITERNVLLTT-KHPFLVCAHYTFQ-TDAK--IFMVLDYVPGGELFGRL
 |.. .||.| .|.| . . |    .|.   | |.. |   | ..|   |  . | ... .  .|| .|. .      .    |..|. |.|.| |   |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

KE----ESLFAESRVRLYAAEICLGLGYLHKLGFIYRDLKPENILVDQDGHLKITDFGLAKNT-DMGTT-STFCGTPE---YIAPEMLQRLPYTKAVDWW
..    .  .  ..   ....|. |. ||.  ..| |||   |.||. ... ||.|||||.   . ..   .  |..      ||| ..   .| . | |
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVW

SYGIIIYEMLT-GLPP-FYDENTNQMYRSI
|.|. ..|..| |  | ...   ...|. |
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYI
Kinase 95725.m00240.AA S_TK_X 383-446 35 4.1e-09 37.53 SMART 1-79 (79) Show / Hide 
Range on Protein: 383-446
Range on HMM: 1-79/79
Sequence Identity: 35% (28 aa)

ASINWENVFN--KKTKPEWKPKIK----NATDTSLFDEEFTHETGGVSFEDGSLIGADTQEQ---------FNGFTCTQ
..|.|....|  |...| .|||||    ..|||| ||.||| ||   .  |  |...  |..         | |||   
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 95725.m00240.AA p70 127-161 44 1.3e-08 27.47 In-house 1-38 (299) Show / Hide 
Range on Protein: 127-161
Range on HMM: 1-38/299
Sequence Identity: 44% (17 aa)

FTILGVLGRGTYGKVQLVKEKE---TGKLFALKTMSKR
|  | |||.| |||| .|.      |||..| | . |.
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKA
Kinase 95725.m00240.AA Pkinase_C 402-443 42 5.2e-07 27.97 Pfam 1-41 (46) Show / Hide 
Range on Protein: 402-443
Range on HMM: 1-41/46
Sequence Identity: 42% (18 aa)

KIKNATDTSLFDEEFTHETGGVSFEDGSLIGADTQEQFNGFT
..|..|||| ||.||| |.   .. |.. . .  ||.| |||
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFT