TVAG_134240

Species: T.vaginalis
Alias: TVAG_134240, TvagK1049
External Links:
Annotation:

Classification

Group: Other
Family: Other-Tvag3

Sequence

Name Sequence Type Origin Length Description Download
TVAG_134240.AA Protein None 2082 None Fasta, JSON
TVAG_134240.kin_dom Protein Kinase Domain None 437 None Fasta, JSON

Protein domain

Protein domains of TVAG_134240.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
IQ TVAG_134240.AA IQ 12-32 38 0.001154 15.74 Pfam 1-21 (21) Show / Hide
Range on Protein: 12-32
Range on HMM: 1-21/21
Sequence Identity: 38% (8 aa)

IDVVVRIQSIFRGYSYRKHLS
 . ...||. .|||  |||. 
HRAAIKIQAWWRGYLARKHYR

IQ TVAG_134240.AA IQ 38-58 38 0.039813 10.76 Pfam 1-21 (21) Show / Hide
Range on Protein: 38-58
Range on HMM: 1-21/21
Sequence Identity: 38% (8 aa)

NRNALKIQNAWKFHLMRQKIQ
 | |.||| .|. .|.|.. .
HRAAIKIQAWWRGYLARKHYR

Kinase TVAG_134240.AA Dicty3 1199-1224 34 6.3e-08 22.04 In-house 326-351 (351) Show / Hide
Range on Protein: 1199-1224
Range on HMM: 326-351/351
Sequence Identity: 34% (9 aa)

SKLFIEIIATCLQIDPAKRPPIEQLL
|... ..|  |.|||| .|. ...|.
SNFCKNFIQHCWQIDPNHRWDMHELI

Kinase TVAG_134240.AA Ciliate-E2 1010-1229 12 1.4e-07 22.1 In-house 176-365 (365) Show / Hide
Range on Protein: 1010-1229
Range on HMM: 176-365/365
Sequence Identity: 12% (37 aa)

LHSKN-IILRTLYPDNIYLNGFQNQVMIGSLLDSQFLESQLAIPLPPKFTDYRN----------------------------------------------
||||| || | . |.|| .                           .| .|  .                                              
LHSKNNIIHRDIKPENILF---------------------------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTIC

---PFLPPEFFHKKASE-------WTTAFDVWQFGMLLLYILTGNLPKSYGEVLMSSLSQETIKKCQSEKQSFEGVLDENVIYPKPNFFYDWLEDFKVVS
   ....|| . .|  .       .... |.| .|..| . |.|..|                                                     
GTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF----------------------------------------------------

SLEKCTGECGEVFIQTDECNIKYSSILQLEHYSLLPYKNTKLNYD--------------------ESKLFIEIIAT----CLQIDPAKRPP-IEQLLRTY
                                 .   |. |....                     |.  . .|      .|| || ||.  .||.|   
---------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHP

PF
 |
WF

Kinase TVAG_134240.AA STE 1199-1230 48 2.2e-07 22.25 In-house 327-359 (359) Show / Hide
Range on Protein: 1199-1230
Range on HMM: 327-359/359
Sequence Identity: 48% (16 aa)

SKLFIEIIATCLQIDPAKRPPIEQLLRT-YPFN
|. |.. |. |||.|| |||  .|||.   || 
SPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI

Kinase TVAG_134240.AA STE20 1199-1230 46 3e-06 19.07 In-house 258-288 (288) Show / Hide
Range on Protein: 1199-1230
Range on HMM: 258-288/288
Sequence Identity: 46% (15 aa)

SKLFIEIIATCLQIDPAKRPPIEQLLRTYPFN
|. | . ...|||.||.|||  .|||.  || 
SPEFHDFVDKCLQKDPEKRPTASQLLK-HPFI

Kinase TVAG_134240.AA NKF1 1079-1099 52 5e-06 16.79 In-house 186-206 (269) Show / Hide
Range on Protein: 1079-1099
Range on HMM: 186-206/269
Sequence Identity: 52% (11 aa)

TAFDVWQFGMLLLYILTGNLP
.. |||||| |. ..|||..|
PSHDVWQFGVLIFCCLTGCFP

Kinase TVAG_134240.AA FRAY 1199-1229 41 7e-06 13.9 In-house 247-277 (277) Show / Hide
Range on Protein: 1199-1229
Range on HMM: 247-277/277
Sequence Identity: 41% (13 aa)

SKLFIEIIATCLQIDPAKRPPIEQLLRTYPF
...| ..|  ||| ||.|||    ||.   |
GHSFKKMIEKCLQKDPSKRPTASELLKHKFF

Kinase TVAG_134240.AA RCK 1203-1230 39 1.5e-05 13.23 In-house 272-298 (298) Show / Hide
Range on Protein: 1203-1230
Range on HMM: 272-298/298
Sequence Identity: 39% (11 aa)

IEIIATCLQIDPAKRPPIEQLLRTYPFN
||..  .||.|| ||. ..|.|. .|. 
IELMEKMLQWDPQKRITAQQALQ-HPYF

Kinase TVAG_134240.AA PLK2 1204-1229 34 1.7e-05 13.39 In-house 232-257 (257) Show / Hide
Range on Protein: 1204-1229
Range on HMM: 232-257/257
Sequence Identity: 34% (9 aa)

EIIATCLQIDPAKRPPIEQLLRTYPF
..||  |  ||. ||......|   |
HLIARMLSPDPEDRPSLDHIIRHDFF

Kinase TVAG_134240.AA CDKL 1199-1229 32 2.8e-05 14.01 In-house 256-286 (286) Show / Hide
Range on Protein: 1199-1229
Range on HMM: 256-286/286
Sequence Identity: 32% (10 aa)

SKLFIEIIATCLQIDPAKRPPIEQLLRTYPF
.|. . ..  ||..||..|.  |||..   |
NKKALDFMKKCLHMDPDERMTCEQLMHHPYF

Kinase TVAG_134240.AA Ciliate-D1 1082-1100 42 3e-05 18.37 In-house 1-19 (19) Show / Hide
Range on Protein: 1082-1100
Range on HMM: 1-19/19
Sequence Identity: 42% (8 aa)

DVWQFGMLLLYILTGNLPK
|.|.||..|...|.|. | 
DIWSFGCILYEMLFGQPPF

S_TKc TVAG_134240.AA S_TKc 828-1229 11 7.6e-05 -105.86 SMART 1-231 (231) Show / Hide
Range on Protein: 828-1229
Range on HMM: 1-231/231
Sequence Identity: 11% (48 aa)

EILGDLVKHELMKRVQESINKSFEKNLLDKMLPVQPIDLKLTQKEPDPNIKFCQMPFRNPELTEIFHRTSFELFPTHVQYGRDMDQKQFLRMFVLTPEIY
  ..... .  . .|   ..|.  .    |...                                                                   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------------------------------------------------------------

KKLSVQIDNVSKYSFVSRKVSICIPQVMTSSTEGFTKIVMTEDMKSL---PLSYFLKVHSFLGAD-PRLLSVAKSICSRCLSMLYNLHSKNIILRTLYPD
      ..  .  .  ..     | .   .  .  ... |  .. .     |  ..| .   | . |    .|....   .. |  .||..|| | | |.
------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPE

NIYLNGFQNQVMIGSLLDSQFLESQLAIPLPPKFTDYRNPF------LPPEFFHKKASEWTT-AFDVWQFGMLLLYILTGNLPKSYGEVLMSSLSQETIK
|| |.    ...|.    . .|                . |      ..|| .      ... . |.| .| .|   |.|  | .          |...|
NILLDE---HIKICDFGLARQL----------------TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCILYEMLCGYPPFP--------QMQMMFK

KCQSEKQSFEGVLDENVIYPKPNFFYDWLEDFKVVSSLEKCTGECGEVFIQTDECNIKYSSILQLEHYSLLPYKNTKLNYDESKLFIEIIATCLQIDPAK
|.                                                                                |. ....|  ||| ||.|
KIG-------------------------------------------------------------------------------SPEAKDFIRKCLQKDPEK

RPPIEQLLR-------TYPF
|| . ..|.          |
RPTA-EALQDEWDIKCHPWF