Gene 97354.m00234 (T.vaginalis)
97354.m00234
Species: T.vaginalis
Alias: TvagK0643, 97354.m00234
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 97354.m00234.AA | Protein | None | 2167 | None | Fasta, JSON |
| 97354.m00234.kin_dom | Protein Kinase Domain | None | 241 | None | Fasta, JSON |
Protein domains of 97354.m00234.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 97354.m00234.AA | FRAP | 1949-2116 | 28 | 1.5e-16 | 57.37 | In-house | 70-241 (251) | Show / Hide |
Range on Protein: 1949-2116 Range on HMM: 70-241/251 Sequence Identity: 28% (50 aa) ISNYRKTRNVKQNVEEEVVLSHTSMNFDDLTSLQRLEVFDTSVRNKIYSFDLRDSLWYLSKNPQQWIDTSTNFSKCFAFDSFLTYYFGIGNRNPDNILID | .||| ... |.| .. .. . ..| |. ... |.| . | ||. || | | |.. ||. . | | | |.| | | ||... IRDYRKKYHIRYNIEYNIMDRMCN-DYDHLPLMNKVEIFRYIMNNTKGE-DLKKLLWLKSPNSEIWFERRTNYTRSLATMSMAGYILGLGDRHPSNIMLQ PQTGRIASIDLYSAL------ERLENDVPLRLTPMFENALDDVEVNGLYSNKIHELMKTLLTNSQKVVDYIYAF .||.| || |.. .|.||| | ||.. ..| | | . || . . . |. . || RYTGKIVHIDFGDCFEVAMRREKFPEKIPFRLTRMLVNAMEACGIEGNYRNTCELVMKVIREHKESVMAVLEAF |
|||||||||
| Kinase | 97354.m00234.AA | PIKK | 1972-2116 | 23 | 1.1e-13 | 46.56 | In-house | 141-290 (290) | Show / Hide |
Range on Protein: 1972-2116
Range on HMM: 141-290/290
Sequence Identity: 23% (36 aa)
SMNFDDLTSLQRLEVFDTSVRNKIYSFDLRDSLWYLSKNPQQWIDTSTNFSKCFAFDSFLTYYFGIGNRNPDNILIDPQTGRIASIDLYSALE-RLE---
.|. ..... ...||| . ... .... .| . .|..| . .|. | .. | |.| |.|.||.|| ||| | .||. . | .
CMMYQHWPLHEKVEVFRE-QMQNTPPDMFKKWFWRKFPDPEIWWERRENYTRSYAVMCMVGYILGLGDRHPENIMIDMQTGEIVHIDFGCCFESAMQRLP
--NDVPLRLTPMFENALDDVEVNGLYSNKIHELMKTLLTNSQKVVDYIYAF
|| |||....||. |.|.. . . |. . . .. .|
VPEKVPFRLTRNMVNAMGPMGVEGVFRRCCEHVMMCMRQHRETLMTVCEVF
|
|||||||||
| Kinase | 97354.m00234.AA | ATR | 2011-2116 | 24 | 1.2e-11 | 35.52 | In-house | 157-267 (267) | Show / Hide |
Range on Protein: 2011-2116 Range on HMM: 157-267/267 Sequence Identity: 24% (27 aa) PQQWIDTSTNFSKCFAFDSFLTYYFGIGNRNPDNILIDPQTGRIASIDLYSALER-----LENDVPLRLTPMFENALDDVEVNGLYSNKIHELMKTLLTN |||| . |. . .| . . | |.| | |||||| .| . .| . || ||| .... .. .||. . . |. . . PQQWYSSRENYCRSYAVWCMVGYIIGLGDRHTDNILIDKINGECVHVDYNCIFNSGEQFEVPEIVPFRLTHNMVFGMGPMKTYGLFRRACEVIMMCMRDH SQKVVDYIYAF . .. .. .| RDDIMSVWDCF |
|||||||||
| Kinase | 97354.m00234.AA | PI3_PI4_kinase | 1976-2124 | 18 | 5.2e-09 | 35.01 | Pfam | 122-300 (300) | Show / Hide |
Range on Protein: 1976-2124 Range on HMM: 122-300/300 Sequence Identity: 18% (33 aa) DDLTSLQRLEVFDTSVRNKIYSFDLRDSLWYLSKNP-QQWIDTSTNFSKCFAFDSFLTYYFGIGNRNPDNILI--DPQTGRIASIDLYSALE-----RLE ..|. .|..||| ... .| . .|.. .| .... | . .|| . .| . ..| .|.| |..|||.. | || .. || ... ... WHLMRMQKVEVF-EMRIMKTPKPGLYQWFWKHNPDAYEEWWEARDNFVRSCAGMCVVDYILGNGDRHNDNIMVKDDKTTGHLFHIDFGHCFPHWKMKHFH N--DVPLRLTP------MFENAL------DDVEVNGLYSNKIHELMKTLLTNSQKVVDYI---------YAFEGEIPSNI . .|| |.|. .. .|. |. . |.. .... | .. .. .. .. | . . KPERVPFRWTHWPQAKKPMVHAMGGYISLDPSGDYGWFRDYCWHAYRALRRHMNLCMNLLKKAVMRGECMVHDGLPMWRS |
|||||||||
| PI3Kc | 97354.m00234.AA | PI3Kc | 1910-2166 | 13 | 2.8e-05 | -82.13 | SMART | 1-333 (336) | Show / Hide |
Range on Protein: 1910-2166
Range on HMM: 1-333/336
Sequence Identity: 13% (44 aa)
AELKKR---------------------TEKSSLCSLDFT-------SFSKNVACLLWPANFIDIKSFISNYRKTRNVKQNVEEEVV--------------
| . | . . . .|.. . ... . | | . . ..|.| ... .... .
AVIFKCGDDLRQDMRMMQMFRLMNKIWQKDKECRRRDLHMRPYKCIPTGPKCGMIEWVPNCETLHQIQKKYHKWKKMPMDYHQWFMFDMLVPEIQKNMYM
------LSHTSMNFDDLTSLQRLEVFDTSVRNKIYSFDLRDSLWYLSKNPQ-QWIDTSTNFSKCFAFDSFLTYYFGIGNRNPDNILIDPQTGRIASIDLY
. | | ...|....|..| . ..... .|.| .| ...| | . .|| . | . || .||| | .|||..| .|| . ||.
MIWHQQACHWMMMYQHMTHMEWLKYF-EGATCPFKPPVLYDWFWEHFPDPNEDWWEARDNFTRSCAGYCMVTYILGIGDRHNDNIMLDMKTGHCFHIDFG
SALER---LEN-------DVPLRLTPMFENALD----DVEVNGLYSNKIHELMKTLLTNSQKVVDYIYAFEGEIP-SNIISE-----MKKKSLQNP-ENS
.... .. || |||... .. . .. |.. .. .. . .| ... .. .. . .. .. . ..... .
HIFGHGPKKPGFKHHHRERVPFRLTHDMVYVMGGGGKPSGYFGYFRTCCCRAYRAMRKHSNLIMNLFEMMVYDPIMPCWRMMEKDIKYLRQRFRLDHLSD
DLIADEL-------ISVSRNPANYTKLCKSWNPL
...| . .. | ...|.. ... .
EEAAQYFMQTMCTKLIEHSNESWTTRMYWMFHNW
|
|||||||||
| Kinase | 97354.m00234.AA | SMG1 | 2004-2058 | 34 | 0.000272 | 9.95 | In-house | 173-227 (242) | Show / Hide |
Range on Protein: 2004-2058 Range on HMM: 173-227/242 Sequence Identity: 34% (19 aa) LWYLSKNPQQWIDTSTNFSKCFAFDSFLTYYFGIGNRNPDNILIDPQTGRIASID || | | . . | | | |.| | ||.||| || . || LWSSCTTPDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHID |
|||||||||