Gene 94174.m00145 (T.vaginalis)

94174.m00145

Species: T.vaginalis
Alias: 94174.m00145, TvagK0335
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
94174.m00145.AA Protein None 1153 None Fasta, JSON
94174.m00145.kin_dom Protein Kinase Domain None 250 None Fasta, JSON

Protein domain

Protein domains of 94174.m00145.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 94174.m00145.AA MLK 218-467 31 2.7e-81 276.37 In-house 1-291 (291) Show / Hide 
Range on Protein: 218-467
Range on HMM: 1-291/291
Sequence Identity: 31% (92 aa)

FVLKKKIGSGGFADVYEGIQQSTQ---KVVAIKILHNNE----ISESLFKSFKREIEIQSKLKNFA----ILELVGVCLEA-P-FYIATEFMPKDCLFKR
. ....||||.| .|. |  . .    |.||.|. . .     ....  . |..|... ..|.       | ...||||.  . |.| .|.... .|.  
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

IHSQTK--------------LEPTKKTIIALGCAIALSYMHKLD---YIHRDIKSLNILLDA------DDYPKICDFGMSRKLLHQ-ELMTGGIGTAQWE
.|....                .  .  .|| || ...| |...   .||||.|| |||.|.      ..  |||||| ||.. .  . |.. .||. | 
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWM

APEVI---SNQMYTEKCDVYSYGILLWEILTGEVPFR-GLTQMQVASDVVGNSHRPVIPNVAPPKITKMIKLCWEQDPNRRPSMETVASAI
|||||    ...|.|||||.|.|..|||.||.|||.. .. .|..|  |. |. || ||. .|. . |..| ||.|||..|||.  . .  
APEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 94174.m00145.AA TKL 224-467 24 7.7e-74 251.62 In-house 1-364 (364) Show / Hide 
Range on Protein: 224-467
Range on HMM: 1-364/364
Sequence Identity: 24% (90 aa)

IGSGGFADVYEGIQQSTQ--------KVVAIKILHNNE-------------------------ISESLFKSFKREIEIQSKLKNFAILELVGVCLEAP--
||||||. || |. . .         |.||.|... ..                          .. ... ...|| . |.|.   |. ..|.|.. |  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------FYIATEFMPKDCLFKRIHSQTKLEPTKKTIIALGCAIALSYMHKLD--------YIHRDIKSLNILLDADDY--------------PK
            ..| .|..|. .|. ..|      . ..  .||..| ...|.|  .         ||||.|| |||.| .                .|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

ICDFGMSRKLLHQE--------------------LMTGGIGTAQWEAPEVISNQ----------------MYTEKCDVYSYGILLWEILTGEVPFRGLTQ
||||| || . . .                         .|| .| ||||. .|                 |.|||||||.||.||||||...|....  
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY

MQVA---------SDVVGNSHRPVIP------------NVAPPKITKMIKLCWEQDPNRRPSMETVASAI
|..          . |. ...|| ||            . .|| . | .. ||..||. |||.... . .
MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 94174.m00145.AA Dicty4 218-461 35 4.8e-67 222.67 In-house 1-267 (277) Show / Hide 
Range on Protein: 218-461
Range on HMM: 1-267/277
Sequence Identity: 35% (96 aa)

FVLKKKIGSGGFADVYEGIQQSTQKVVAIKIL--HNNEISESLFKSFKREIEIQSKLKNFAILELVGVCL---EAP--FYIATEFMPKDCLFKRIHS---
 .  ..||.|.|. || |.    .| ||.|.|  ||   .|.. ..|..|..| .|. .  |. . | |.    .|  . | ||.|||  |.. .|.   
INIEQRIGKGSFGEVYKGTWR--GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPS

----QTKLE-PTKKT--IIALGCAIALSYMHK--LDYIHRDIKSLNILLDADDYPKICDFGMSR----KLLHQELMTGGIGTAQWEAPEVISNQMYTEKC
     .||. |. |    .|. .|  . . |    . ||||.|| |.| |..   |.|||| |.       |.  ... .||. |.||||  .| |.|| 
EQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKA

DVYSYGILLWEILTGEVPFR--GLTQMQVASDVVGNSHRPVIPNVAPPKITKMIKLCWEQDPNRRPSME
||||.||.||||||.. |.   .   ||..  |.    || ||.  ||.... |. ||. ||..|||.|
DVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFE
Kinase 94174.m00145.AA TKL-Unique 220-467 31 3.2e-62 213.02 In-house 1-290 (290) Show / Hide 
Range on Protein: 220-467
Range on HMM: 1-290/290
Sequence Identity: 31% (91 aa)

LKKKIGSGGFADVYEGIQQSTQKVVAIKILH-NNEISESLFKSFKREIEIQSKLK-NFAILELVGVCL----EAP-FYIATEFMPKDCLFKRIH------
  .|||.||.. || |.  ...  ||||..| |...| .. . |..|. . .||.    |. ..|.|      .| ..| .|..|   | . .|      
FWNKIGEGGYGQVYKGKWRGYP--VAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

----SQTKLEPTKKTIIALGCAIALSYMHKLD--YIHRDIKSLNILLDAD-----DYPKICDFGMSRKLLHQELMTGG----------IGTAQWEAPEVI
    . .|| . ..  .|. .| .. | | ..   ||||.||.|.|.| .        |||||| |. .     || .          .|...| ||||.
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

SN--QMYTEKCDVYSYGILLWEILTGEV------PFRGLTQMQVASDVVG--NSHRPVIPNVAPPKITKMIKLCWEQDPNRRPSMETVASAI
..   .|.||.||||.|| ||||.|...      |..|..| |... |     . || |||  |. ... |. || .||  ||| ... . .
RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 94174.m00145.AA Dicty4-Unclassified 218-467 34 3.2e-60 204.96 In-house 1-263 (263) Show / Hide 
Range on Protein: 218-467
Range on HMM: 1-263/263
Sequence Identity: 34% (91 aa)

FVLKKKIGSGGFADVYEGIQQSTQKVVAIKILHNNEIS--ESLFKSFKREIEIQSKLKNFAILELVGVCLEAP------FYIATEFMPKDCLFKRIH---
    . || | |. |. |.     | ||.|..  |  .  | . . ||.|.||   .     . . | |. .|      . | .|||.|  ||  ||   
IQIDQFIGKGHFSKVHKGNWKG--KDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCI-NPRSHKSTMCIVMEFMHKGNLFEVIHSKP

----SQTKLEPTKKTIIALGCAIALSYMHKLDYIHRDIKSLNILLDADDYPKICDFGMSRKLLHQELMTGGIGTAQWEAPEVISNQMYTEKCDVYSYGIL
       ||. |    .|.  |  . ..|  . ||||||| |||.| .   || |||.||       ||   ||  ||.||.     |. | |||||...
SEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMM

LWEILTGEVPFRGLT-QMQVASDVVGNSHRPVIPNVAPPKITKMIKLCWEQDPNRRPSMETVASAI
|.| .||. |. .    | .|  |     || ||   .. . |.|| ||  |||.||.|. .    
LYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase 94174.m00145.AA Pkinase 218-467 26 1.8e-58 205.34 Pfam 1-293 (293) Show / Hide 
Range on Protein: 218-467
Range on HMM: 1-293/293
Sequence Identity: 26% (79 aa)

FVLKKKIGSGGFADVYEGIQQSTQKVVAIKILHNNEISESLFKSFKR--EIEIQSKLKNFAILELVGVCL-EAPFYIATEFMPKD----CLFKRIH--SQ
.....|||||.|. ||... ..|.|.||.||.   .....  ..  |  ||.|  .|.   |..| ...  .   |. .|.....     || .|.  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

TKL--EPTKKTIIALGCAIALSYMHKLDYIHRDIKSLNILLDADDYP----KICDFGMSRK--LLHQELMTGGIGTAQWEAPEVIS-NQMYTEKCDVYSY
...  ..     ...  . .| |.|.   ||||.|. |||.| ....    |||||| ...  . ... ||.  ||  . |||||  .|.|. |.|..|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GILLWEILTGEVPFRGL------TQMQVASDVVGNSHRPVIPNVAP-------------------PKITKMIKLCWEQDPNRRPSMETVASA--I
|..|.| |.|. ||.|       .|||.   . |   .  .|.  .                   .   . || |...||..||. | .     .
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 94174.m00145.AA S_TKc 218-473 29 8.3e-57 195.96 SMART 1-231 (231) Show / Hide 
Range on Protein: 218-473
Range on HMM: 1-231/231
Sequence Identity: 29% (80 aa)

FVLKKKIGSGGFADVYEGIQQSTQKVVAIKILHNNEISESLFKSFKREIEIQSKLKNFAILELVGVCLEAPFYIATEFMPK--DCLFKRIHSQTK-----
. . .|||.|.|. || ..  .|...|||||..         ....|||.| .| .   |  | .|. .  .|. .|...     ||..|... .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LEPTKKTIIALGCAIALSYMHKLDYIHRDIKSLNILLDADDYPKICDFGMSRKLLHQELMTGGIGTAQWEAPEVISNQMYTE-KCDVYSYGILLWEILT
 . .     ..   . || |.|..  ||||.|  |||||     ||||||..|.|      |  .||  . ||||.    |.  |||..| |..|.| |.
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

GEVPFRGLTQMQVASDVVGNSHRPVIPNVAPPKITKMIKLCWEQDPNRRPSMETVAS---AIACGEVV
|. ||.   |||.  ...|           .|    .|. |.. ||..||.   .     .|.| . .
GYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 94174.m00145.AA LRRK 218-469 24 4.5e-56 192.6 In-house 1-351 (351) Show / Hide 
Range on Protein: 218-469
Range on HMM: 1-351/351
Sequence Identity: 24% (87 aa)

FVLKKKIGSGGFA-DVYEGIQQS--------------------------TQKVVAIKILHNN---------------------------------EISES
..  ..||.|||.  || .. ..                            . ||||...                                   . ...
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

LFKSFKREIEIQSKLKNFAILELVGVCLEAPFYIATEFMPKDCLFKRIH----SQ-----TKLEPTKKTIIALGCAIALSYMHKLD--YIHRDIKSLNIL
 | .| .|. | |.|.   |. |.|.|.. |. ...|..|   | ...|    ..     ... .. |  |||  | .. |.|. .   |||| || |||
-FREFRHEVWIMSHLNHPNIVSLKGFCIH-PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNIL

LDADDYP------------KICDFGMSR--KLLHQELMTGGIGTAQWEAPEVISNQ---MYTEKCDVYSYGILLWEILTGE-VPFRGLT-Q-----MQVA
|   . .            ||.||| ||  . .| ..  |  |. .| |||.. .     |||| |.||.|..|||.||..  ||....       |   
LWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQI

SDVVGNSHRPVIPNV-APP-----KITKMIKLCWEQDPNRRPSMETVASAIAC
.| . . .||.||.   ||        . |..||..||..||..... . .  
EDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 94174.m00145.AA HH498 218-467 29 4.4e-55 172.9 In-house 1-284 (284) Show / Hide 
Range on Protein: 218-467
Range on HMM: 1-284/284
Sequence Identity: 29% (84 aa)

FVLKKKIGSGGFADVYEGIQQSTQKVVAIKILHNNEISESLF------KSFKREIEIQSKLKNFAILELVGVCLEAP--FYIATEFMPKDCLFKRI----
.  ..||||| | .|| |      |.||.|    . ....          | ||. | ..| ..     |. |.. |  | | |..     || .     
IEFHEKIGSGSFGKVYKGEWR--NKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYACCDDPSQFAIVTQYCDNGSLFSILNTIP

----------HSQT----KLEPTKKTIIALGCAIALSYMHK-LDY--IHRDIKSLNILLDADDYPKICDFGMSR--KLLHQELMTGGIGTAQWEAPEVIS
          | |      . .  | .|..  |    | |  |    ||||  | |||...|   .. ||| ||  . .| . ||  .|   | |||| |
IGGAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFS

-NQMYTEKCDVYSYGILLWEILTGEVPFRGLTQMQVASDVVGNSHRPVIPNV----APPKITKMIKLCWEQDPNRRPSMETVASAI
 .| |..| ||.||.. .||..|.||||  . .   | ..   . || ||.      | ..  .|  ||.. |. ||.   .   .
QCQKYSIKVDVFSYAMCIWEMHTREVPFHHYKPAAAAAEMAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL
Kinase 94174.m00145.AA Pkinase_Tyr 218-467 29 1.4e-53 182.08 Pfam 1-270 (270) Show / Hide 
Range on Protein: 218-467
Range on HMM: 1-270/270
Sequence Identity: 29% (80 aa)

FVLKKKIGSGGFADVYEGIQQ----STQKVVAIKILHNNEISESL--FKSFKREIEIQSKL-KNFAILELVGVCL--EAP--FYIATEFMPKDCLFKRIH
 .. ||.|.| | .||.|.      .|.  ||.|.| ..  ...    ..| ||..| ..| ..  |. |.|||.  . |   || .|.||. .| .  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

S----QTKLEPTKKTIIALGCAIALSYMHKLDYIHRDIKSLNILLDADDYPKICDFGMSRKL-----LHQELMTGGIGTAQWEAPEVISNQMYTEKCDVY
.    . .| .  .  ...  | ...| .   .||||.   |.|.. .   ||||||..| .           .||     | |||.|..  .|.| ||.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDVW

SYGILLWEILT-GEVP-FRGLTQMQVASDVVGNSHRPVIPNVAPPKITKMIKLCWEQDPNRRPSMETVASAI
|.|.|.|||.| || | . |..  .|   .  . .|  .|  .|..| ...|.||..||..||... . . .
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 94174.m00145.AA DRK 218-469 34 1.8e-51 172.62 In-house 1-258 (258) Show / Hide 
Range on Protein: 218-469
Range on HMM: 1-258/258
Sequence Identity: 34% (89 aa)

FVLKKKIGSGGFADVYEGIQQSTQKVVAIKILHNNEIS-ESLFKSFKREIEIQSKLKNFAILELVGVCLEAP-FYIATEFMPKDCLFKRIHSQT-KLEPT
 .    || |....|. |    ||  ||.| | |  |  | . . |.|||.. ..|    |    | |.. |   | .|.||.  | .  | .  ...  
IKIGNRIGRGNYGEVFRGTWRGTQ--VAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWP

KKTIIALGCAIALSYMHKLD--YIHRDIKSLNILLDADDYPKICDFGMSR---KLLHQELMTGGIGTAQWEAPEVISNQMYTEKCDVYSYGILLWEILTG
    ... ||  . | |  .   |||| || | | |     |. ||| |    | . .      .||  | ||||  || |||| ||||..| |||..| 
LMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWECVTR

EVPFRGLTQMQVASDVVGNSHRPVIPNVAPPKITKMIKLCWEQDPNRRPSMETVASAIAC
. |. |   .||   |     || .|   ||| .. .. ||. ||  ||||. .   .  
QDPYFGMPTFQVVFSVGRHGMRPPMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase 94174.m00145.AA TyrKc 218-467 27 3.7e-51 177.21 SMART 1-280 (280) Show / Hide 
Range on Protein: 218-467
Range on HMM: 1-280/280
Sequence Identity: 27% (79 aa)

FVLKKKIGSGGFADVYEGIQQSTQKVVAIKILHNNEISESLFKSFKREIEIQSKL--KNFAILELVGVCLE--------APFYIATEFMPKDCLFKRIHS
 .|.||.|.| |  ||.|.       ||.| |...       . | ||..| .||  ..  |. |.|||..         | .| .|.||. .| .....
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

QTK-LEPTKKTIIALGCAIALSYMHKLDYIHRDIKSLNILLDADDYPKICDFGMSRKLLHQ-------ELMT-----GGI--GTAQWEAPEVISNQMYTE
  . | . ..  ...  |   .| |.  .||||.   |.|....   ||.|||.||.. .        .  .     ||       | |||.|   ..|.
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KCDVYSYGILLWEILT-GEVPFRGL----TQMQVASDVVGNSHRPVIPNV--------APPKITKMIKLCWEQDPNRRPSMETVASAI
| ||.|.|...|||.| |. |  |        | .   | . .|. .|          .|... ...| ||. ||. ||..... . .
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 94174.m00145.AA TK 218-467 14 9.7e-51 167.91 In-house 1-486 (486) Show / Hide 
Range on Protein: 218-467
Range on HMM: 1-486/486
Sequence Identity: 14% (73 aa)

FVLKKKIGSGGFA---DVYEGIQQSTQK-------------------------VVAIKILHNN-EISESLFKS--------------FKREIEIQS--KL
 .| ||.|.| |    .||.|. ..  .                          ||.|.|.   . |.  |.               . .|... .  ..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

KNFAILELVGVCLEA-------------PFYIATEFMPKDC----LFKRIHSQTK---------------------------------------------
.   |. |.|||..              |..| .|.||. .    | .  ..  .                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LEPTKKTIIALGCAIALSYMHKL------DYIHRDIKSLNILLDADDY-----------PKICDFGMSR
                               | .  .  ...  | ...|.|..       ..|||.   |.|.. ..             ||.|||.||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

K----LLHQELMTGGIGTAQ-------------------------------WEAPEVISNQM---------YTEKCDVYSYGILLWEILT-GEVPFRG-L
.    |       .   ...                               | |||..  .          .|.| ||.|.|.|.|||.| |..|. | .
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TQ---------MQVASDVV-------------GNSHRPVIPNVAP--------------PKITKMIKLCWEQDPNRRPSMETVASAI
.           .|   ..             |. .|.  |  .|              . .  ... ||. ||..||..... ...
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 94174.m00145.AA TKL-ciliate1 220-467 26 7.3e-45 151.49 In-house 3-279 (279) Show / Hide 
Range on Protein: 220-467
Range on HMM: 3-279/279
Sequence Identity: 26% (75 aa)

LKKKIGSGGFADVYEGIQQSTQKVVAIKILHNNEISE--SLFKSFKREIEIQSKLKNF-AILELVGVCLE-APFYIATEFMPKDCLFKRIHSQTK----L
...||||| |  || |  .|  ..|||. .  .  .|     | | |||.  .|.|..   ..|.|. .    ||| .|. .|  .|   |   .    .
MGQKIGSGHFCNVYKGRCNS--YDVAIMNMNYFNSQESFINQKEFQREIQQHIKIKQHINLQQLQGISFYDNNFYIIMEHCHKGTMFDICHRKHSQIYMI

EPTKKTIIALGCAIALSYMHKLD--YIHRDIKSLNILLDADDYPKICDF--------GMSRKLLHQEL--MTGGIGTAQWEAPEVI-----SNQMYTEKC
       .    |  ..|.|..    ||||.|..|||.| .  .|||.|        .  |.   |..   ..  .|  | |||..     .|. ..|| 
KWQHRMRWCKDIAQGMQYLHMRQNPLIHRDLKMQNILYDEPYQYKICNFPHVKIADFHRIRNCSFQDMQNEMQRNTTFHWMAPEQMDPHIFPNYPINEKI

DVYSYGILLWEILTGEVPFRGLTQMQVASDVVGNSHRP--------VIPNVAPPKITKMIKLCWEQDPNRRPSMETVASAI
|.|.|||....    . ||    .| |..  .  .  |         |.   |. . .... ||.|.|| ||. . .   .
DIYAYGIVMYILCFRKTPFQ--QKMSVINIMCYWCEFPGRPNLGPQFIHFDCPQNFHNLMMRCWCQNPNKRPNFNEIIQIL