88783.m00065

Species: T.vaginalis
Alias: TvagK1005, 88783.m00065
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
88783.m00065.AA Protein None 295 None Fasta, JSON
88783.m00065.kin_dom Protein Kinase Domain None 164 None Fasta, JSON

Protein domain

Protein domains of 88783.m00065.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 88783.m00065.AA TKL 47-210 15 3.8e-14 47.35 In-house 163-364 (364) Show / Hide
Range on Protein: 47-210
Range on HMM: 163-364/364
Sequence Identity: 15% (34 aa)

HSDLKPDNIIIDGNFV--------------AHVIDFG---EMSAKKNFLIS---------------TTHAPHGNRCFSAPET-----------------E
| |||..|| .| |.               . . |||   .|| ..|   .               ||. . |. .. |||                  .
HRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCK

KLTYYPASDIYSLGCIIYNMIFKMIPFESYASKNNELL-------KKKQEKFERVHHLKAPSKETYLVTLLKQVDSMEKYESTYDPSQMTVRDELIEIIK
...| ...|.|| | ... ..   .|.. | .   ..        ..  .|..|      ..                ..     .   .. ........
GFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQN---------------HH-K-M-CPCPDCPPSMKKLMQ

KCTLKERESRPKAEELCELI
.|   . |.|| ..|. . .
DCWDHDPEKRPSFQEILKRL

Kinase 88783.m00065.AA Ciliate-E2-Unclassified 47-208 18 1.1e-13 43.92 In-house 167-348 (352) Show / Hide
Range on Protein: 47-208
Range on HMM: 167-348/352
Sequence Identity: 18% (38 aa)

HSDLKPDNIIID--G-NFVAHVIDFGEMS-------------AKKNFLISTTHAPH-GNRCFS----APETEKL-TYY----PASDIYSLGCIIYNMIFK
| |.||.||..|  | |.   .||||  .             .|......       |. ..     |||  .   |.     ..||.|||.|.| |.| 
HRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFG

MIPFESYASKN---------------NELLKKKQEKFERVHHLKAPSKETYLVTLLKQVDSMEKYESTYDPSQMTVRDELIEIIK----KCTLKERESRP
  ||... ..                . . ..|| ...  .. .                             ... .| ...|.    |.  |  ..|.
YYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQ-------------------------IPKHWSPEAKDFINDLLQKMLKKNPNKRI

KAEELCE
 .|....
TFEQILN

Kinase 88783.m00065.AA Pkinase 47-124 36 1.7e-12 45.26 Pfam 131-212 (293) Show / Hide
Range on Protein: 47-124
Range on HMM: 131-212/293
Sequence Identity: 36% (31 aa)

HSDLKPDNIIIDGNFVA----HVIDFGEMSAKK--NFLISTTHAPHGNRCFSAPET--EKLTYYPASDIYSLGCIIYNMIFKMIPF
| ||||.|| || | .     ...|||  .||.  .   | .. . | . . |||   .   | |..|..|.|||.| |...  ||
HRDLKPENILIDNNGHIDACVKICDFG--LAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPF

Kinase 88783.m00065.AA Ciliate-E2 49-206 15 9.4e-12 36.61 In-house 186-359 (365) Show / Hide
Range on Protein: 49-206
Range on HMM: 186-359/365
Sequence Identity: 15% (35 aa)

DLKPDNIIIDGNFVAHVIDFG---------------EMSAKKNFLISTTHAPHG----------------NRCFSAPETEKLT----------YYPASDI
|.||.||..       .||||                .. .. |  . |.   |                .  . |||  .            |  ..||
DIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDI

YSLGCIIYNMIFKMIPFESYASKNNELLKKKQEKFERVHHLKAPSKETYLVTLLKQVDSMEKYESTYDPSQ---------------MTVRDELIEIIKK-
.|||.|.| |.|.  ||                                        .  .. .  ... .                 . .| . .||| 
WSLGVILYEMLFGKPPF---------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKF

---CTLKERESRPK-AEEL
   .  |. | |.  .|..
GKRMLQKDPEKRITGWEQI

S_TKc 88783.m00065.AA S_TKc 3-215 15 1.1e-07 -64.09 SMART 1-231 (231) Show / Hide
Range on Protein: 3-215
Range on HMM: 1-231/231
Sequence Identity: 15% (44 aa)

FISGVTL----------------------------------------DNLVKYLITNQLDFRDYQILAISYVIS---YVLGKLGAHK-------------
.  . ..                                        .|.||.. . |    |.  .   |.      ..  .  ..             
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPEHAR

-------------------HSDLKPDNIIIDGNFVAHVIDFGEMSAKKNFLISTTHAPHGNRCFSAPETEKLTYYP-ASDIYSLGCIIYNMIFKMIPFES
                   | ||||.|| .|   .  ..|||  .|..       .   | . . |||     | . ..|..|.|||.| |.    ||. 
FYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFG--LARQL------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLCGYPPFP-

YASKNNELLKKKQEKFERVHHLKAPSKETYLVTLLKQVDSMEKYESTYDPSQMTVRDELIEIIKKCTLKERESRPKAEELCE----LIRNIAI
     ....||                                             .|....|.||  |. | || | |. .          .
---QMQMMFKKIG------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 88783.m00065.AA Ciliate-D1 106-124 57 3.2e-07 25.37 In-house 1-19 (19) Show / Hide
Range on Protein: 106-124
Range on HMM: 1-19/19
Sequence Identity: 57% (11 aa)

DIYSLGCIIYNMIFKMIPF
||.|.|||.|.|.|.. ||
DIWSFGCILYEMLFGQPPF

Kinase 88783.m00065.AA CAMK 47-126 21 4.7e-07 18.01 In-house 202-336 (425) Show / Hide
Range on Protein: 47-126
Range on HMM: 202-336/425
Sequence Identity: 21% (29 aa)

HSDLKPDNIIIDGN-----------------FVAHVIDFGEMSAKKNFLIS-----------------------TTHAPHGNRCFSA-PETEK-------
| ||||.|| .| |                 .   .|||| ...|..   .                         . . |  .. | ||  .       
HRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFG-FANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------LTYY-PASDIYSLGCIIYNMIFKMIPFES
        .|| |..|. |.|.| | |     ||..
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYG

Kinase 88783.m00065.AA ULK 97-141 32 7.4e-07 20.07 In-house 228-272 (329) Show / Hide
Range on Protein: 97-141
Range on HMM: 228-272/329
Sequence Identity: 32% (15 aa)

EKLTYYPA-SDIYSLGCIIYNMIFKMIPFESYASKNNELLKKKQEK
|.  || . .||.|||||.| |..   ||...      |.......
EQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLI

Kinase 88783.m00065.AA Ciliate-A1 47-116 27 1e-06 18.84 In-house 124-220 (301) Show / Hide
Range on Protein: 47-116
Range on HMM: 124-220/301
Sequence Identity: 27% (27 aa)

HSDLKPDNIIIDGNFVAHVIDFGEMSAKKNFLI------------------STTHAPHGNRCFSAPET----------EKLTYYPASDIYSLGCIIYN
|.||||.||.|       ..|.| ||    .                    . |    ||. . .||            .   |  ||.|||||||..
HRDLKPQNILIHFDDKWKICDLG-MSKQLEQNQDCCDDVNGCSFSKQVNKHYHTCKKGGNLYYMSPEQYQMHYRDQMFIENKIYKQSDMYSLGCIICF

Kinase 88783.m00065.AA Ciliate-E3 47-70 51 1e-06 17.04 In-house 126-152 (202) Show / Hide
Range on Protein: 47-70
Range on HMM: 126-152/202
Sequence Identity: 51% (14 aa)

HSDLKPDNIIIDGNF---VAHVIDFGE
|||.||||| .| |    ..   ||||
HSDIKPDNILVDKNNNQLIIKICDFGE

Kinase 88783.m00065.AA TTK 103-126 45 1e-06 17.98 In-house 260-283 (344) Show / Hide
Range on Protein: 103-126
Range on HMM: 260-283/344
Sequence Identity: 45% (11 aa)

PASDIYSLGCIIYNMIFKMIPFES
..||. |.|||.| ||.   || .
CKSDVWSCGCILYYMIYGKTPFQH

Kinase 88783.m00065.AA Ciliate-E9 47-74 53 9e-06 13.96 In-house 135-161 (298) Show / Hide
Range on Protein: 47-74
Range on HMM: 135-161/298
Sequence Identity: 53% (15 aa)

HSDLKPDNIIIDGNFVAHVIDFGEMSAK
| ||||.|..|| |.   ..||| |||.
HRDLKPENMLIDKNYNMKICDFG-MSAQ

Kinase 88783.m00065.AA Ciliate-E3 105-118 35 0.000723 8.28 In-house 189-202 (202) Show / Hide
Range on Protein: 105-118
Range on HMM: 189-202/202
Sequence Identity: 35% (5 aa)

SDIYSLGCIIYNMI
||.||.| ..  ..
SDYYSVGAVFCQLC

Kinase 88783.m00065.AA Ciliate-E9 106-131 38 0.00242 6.1 In-house 207-232 (298) Show / Hide
Range on Protein: 106-131
Range on HMM: 207-232/298
Sequence Identity: 38% (10 aa)

DIYSLGCIIYNMIFKMIPFESYASKN
||.|.||| . |..   || .  . |
DIFSAGCILFMMVMNQYPFFHTNCYN