94534.m00175

Species: T.vaginalis
Alias: 94534.m00175, TvagK0339
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
94534.m00175.AA Protein None 1061 None Fasta, JSON
94534.m00175.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of 94534.m00175.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 94534.m00175.AA TKL 228-472 23 6.6e-68 231.92 In-house 1-364 (364) Show / Hide
Range on Protein: 228-472
Range on HMM: 1-364/364
Sequence Identity: 23% (87 aa)

LGTGGFGTVYRSTRIS--------TGELLAIKEVRN-------------------------DRITMGTWASLYSEIATMAKLKNRYILELVG-THIKQP-
.| ||||.||. .           ||.  |.|  .                          |. ..     .  ||  | .|.   |. ..|     .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YRIITRFCPGKSLFERLHRPCVPLTPLHLTQIAYQMAVGIAYLHSLG--------IVHRDLKTLNIILDEDEA--------------A
            . |.. .||| ||...||       . .. ..|...| |..|||| .        |.|||||. || .||.                .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

IIADFGLCGFVDNNEG--------------------LVGGVGTPHYTAPEVLAHK----------------RYGLKVDTYSFGIILWEMATNQIPYRDKT
 |.||||. |......                    .   .||| . |||||  .                 |  |.| |||||.|||..| ..||.|  
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

QAEIY---------SHVVTHGWHLKIP------------SSVPDGLRRLILRCWSIDPNDRPDFDEIVDSF
  ...         . |. .| .. ||            ...|.....|. .||. ||..|| |.||.. .
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Pkinase 94534.m00175.AA Pkinase 222-472 25 1.9e-63 221.87 Pfam 1-293 (293) Show / Hide
Range on Protein: 222-472
Range on HMM: 1-293/293
Sequence Identity: 25% (75 aa)

IALDDALGTGGFGTVYRSTRISTGELLAIKEVRNDRITMGTWASLYS--EIATMAKLKNRYILELVGTHI--KQPYRIITRFCPGK----SLFERLH-RP
. .   .| |.||.||. ....||.. |.|... ... .. . ..    ||. |..|.  .|..| ..    . .| ... .|.|     .||.... . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIY-MVMEYCEGGLYVMDLFDYISTWR

CVPL--TPLHLTQIAYQMAVGIAYLHSLGIVHRDLKTLNIILDEDEAA----IIADFGLCGF--VDNNEGLVGGVGTPHYTAPEVLA-HKRYGLKVDTYS
  ..  .. ..  ..||.. |..|.|| ||.|||||  || .|..        |.||||. .    ||. . . .|||.| ||||.  .. || ||| .|
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

FGIILWEMATNQIPYRDK------TQAEIYSHVVTHGWHLKIPSSVP-------------------DGLRRLILRCWSIDPNDRPDFDEIVDS--F
.|.||.||.. . |....      .| ...  .    .|  .| . .                   . .. .| .|.  ||..|| ...|. .  |
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 94534.m00175.AA MLK 222-472 27 3.2e-58 199.72 In-house 1-291 (291) Show / Hide
Range on Protein: 222-472
Range on HMM: 1-291/291
Sequence Identity: 27% (80 aa)

IALDDALGTGGFGTVYRSTRISTGEL-----LAIKEVRNDRITMGT----WASLYSEIATMAKLKNRY----ILELVGTHIKQPYR--IITRFCPGKSLF
| .   .| |.|| |.. .    ...     .|.|.|| . . ..        .  |.   ..|. .     | ...|. ...|.   |.. .|.| ||.
IQFHEWIGSGSFGKVWKGRWR--NKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLY

ERLHR-PC------------VPLTPLHLTQIAYQMAVGIAYLHSLG---IVHRDLKTLNIILDE------DEAAIIADFGLCGFVDNN-EGLVGGVGTPH
. ||  .             .  .. |. ..|.|.| |..||||.    |.|||||  || .||      .. . |.|||.  .. .. .   .  ||. 
NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYA

YTAPEVL---AHKRYGLKVDTYSFGIILWEMATNQIPYR-DKTQAEIYSHVVTHGWHLKIPSSVPDGLRRLILRCWSIDPNDRPDFDEIVDSF
. ||||.    . .|  |.| .|.|..|||| | ..||. .  ...|   |. .| .. |||. |... .|. .||. ||..||.|..||  .
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL

Kinase 94534.m00175.AA S_TKc 222-473 26 8.5e-58 199.25 SMART 1-231 (231) Show / Hide
Range on Protein: 222-473
Range on HMM: 1-231/231
Sequence Identity: 26% (70 aa)

IALDDALGTGGFGTVYRSTRISTGELLAIKEVRNDRITMGTWASLYSEIATMAKLKNRYILELVGTHIKQPYRIITRFCPG--KSLFERLHRPCVP----
  . . .| |.||.||. . ..||.. |||...          ....||. . | .  .|  | ..   . . ... .|.|   .||.....   .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LTPLHLTQIAYQMAVGIAYLHSLGIVHRDLKTLNIILDEDEAAIIADFGLCGFVDNNEGLVGGVGTPHYTAPEVLAHKRYGL-KVDTYSFGIILWEMAT
 ... |   ..||.. ...|.||.||.|||||  || |||     |.||||. ..         .|||.| |||||    ||  |.| .|.|.||.||..
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

NQIPYRDKTQAEIYSHVVTHGWHLKIPSSVPDGLRRLILRCWSIDPNDRPDFDEIVD--------SFS
 . |..  ...... ...            .. .. .| .|.  ||..||   |.           . 
GYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 94534.m00175.AA TKL-Unique 266-472 30 1.3e-50 174.45 In-house 42-290 (290) Show / Hide
Range on Protein: 266-472
Range on HMM: 42-290/290
Sequence Identity: 30% (77 aa)

LYSEIATMAKLK-NRYILELVGTHI----KQP-YRIITRFCPGKSLFERLH---------RPCVPLTPLHLTQIAYQMAVGIAYLHSLG--IVHRDLKTL
...|. .| ||.    |. ..|. .    ..| . |.. .||| || . ||         ..  .|...   ..| ..| |  |||...  | |||||..
FENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSS

NIILDED-----EAAIIADFGLCGFVD-NNEGLVGG---------VGTPHYTAPEVLAH--KRYGLKVDTYSFGIILWEMATNQI------PYRDKTQAE
|. .|..       . |.||||. | . .|.. ...         .|.. . |||||    . |  |.| |||||.|||.||..|      ||.. .| .
NFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQ

IYSHVVT--HGWHLKIPSSVPDGLRRLILRCWSIDPNDRPDFDEIVDSF
... | .   . ...||.. |  .| || .||  || .|| ||||. . 
WCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL

Kinase 94534.m00175.AA Pkinase_Tyr 222-472 29 4.1e-47 160.18 Pfam 1-270 (270) Show / Hide
Range on Protein: 222-472
Range on HMM: 1-270/270
Sequence Identity: 29% (79 aa)

IALDDALGTGGFGTVYRSTRI----STGELLAIKEVRNDRITMGT---WASLYSEIATMAKL-KNRYILELVGTHI--KQP--YRIITRFCPGKSLFERL
| ..  || | ||.||. |      .|.   |.| ...   .|     .... .|...| .| ..  |. |.|  .  ..|  . |.. ..|. .| . |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

HRP---CVPLTPLHLTQIAYQMAVGIAYLHSLGIVHRDLKTLNIILDEDEAAIIADFGLCGFV---DNN-EGLVGGVGTPHYTAPEVLAHKRYGLKVDTY
...     |||. .| |...| | | .||.| ...|||| . |. ..|.  . |.||||.  .   |.      ||      .|||.......  | | .
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVW

SFGIILWEMAT-NQIP-YRDKTQAEIYSHVVTHGWHLKIPSSVPDGLRRLILRCWSIDPNDRPDFDEIVDSF
|||. .||. |  ..| | . . .|.| ..  .|  ...|   || . .|...||  ||.||| | ||.  .
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase 94534.m00175.AA Dicty4 295-474 32 4.1e-47 155.28 In-house 79-277 (277) Show / Hide
Range on Protein: 295-474
Range on HMM: 79-277/277
Sequence Identity: 32% (65 aa)

IITRFCPGKSLFERLHR------PCVPLT-PLHLT--QIAYQMAVGIAYLHS--LGIVHRDLKTLNIILDEDEAAIIADFGLCG----FVDNNEGLVGGV
| | ..|  .|.. ||       . ..|  || .   ..|   | |...||.    |.|||||. |.  |..  . ..||||        |.. .. . .
IVTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTAC

GTPHYTAPEVLAHKRYGLKVDTYSFGIILWEMATNQIPYR--DKTQAEIYSHVVTHGWHLKIPSSVPDGLRRLILRCWSIDPNDRPDFDEIVDS--FSS
||| ..||||..|..|  |.| |||||.|||..| |.||    .   ...  |. ..  ..||...|. ...|| .||. ||. || | ||.      .
GTPCWMAPEVMMHQPYNEKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH

Kinase 94534.m00175.AA STE 222-467 21 8.1e-46 158.54 In-house 1-350 (359) Show / Hide
Range on Protein: 222-467
Range on HMM: 1-350/359
Sequence Identity: 21% (76 aa)

IALDDALGTGGFGTVYRSTRI------STGEL---------LAIKEVRNDRITM---------------GTWASLYSEIATMAKLK--NRYILELVGTHI
  . . .| |.|||||.  ..      .|||.          |||... .. .                  . ..  || .| |..    .| .  |...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

KQP--------YRIITRFCPGKSLFERLHRPCVPLTPLH----------LTQI---AYQMAVG-IAYLHSLGIVHRDLKTLNIILDEDEAAIIADFGLCG
|            |.  ...| || . ... . .. ||.           .||   ..|   |  .||||..|.|||.|  || |     . ..|||.||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

FVDNN--EGLVGG-----------------VGTPHYTAPEVLAH------KRYGLKVDTYSFGIILWEMATNQIPYRDKTQAEIYSHVVTH---------
 ....  ..   .                 |||| . ||||.        | |. |.| .|.|. ..|||| . |. | .  . . .  .          
QLTDSMANI-Q-SNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQ

-----GWHLKIPS-------------------SVPDGLRRLILRCWSIDPNDRPDFDE
     | . ..|.                   .. . ..  | .|  .|||.||. ..
LCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ

Kinase 94534.m00175.AA TyrKc 222-472 26 2.4e-45 157.86 SMART 1-280 (280) Show / Hide
Range on Protein: 222-472
Range on HMM: 1-280/280
Sequence Identity: 26% (77 aa)

IALDDALGTGGFGTVYRSTRISTGELLAIKEVRNDRITMGTWASLYSEIATMAKL--KNRYILELVGTHIK--------QPYRIITRFCPGKSLFERLHR
| |.. || | ||.||. | .   .  |.| ...|       . ...|.  | ||  ..  |. |.|  ..        .|. |.. ..|. .| ..|..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

PCVPLTPLHLTQIAYQMAVGIAYLHSLGIVHRDLKTLNIILDEDEAAIIADFGLCGFVDNN-----EGLVGGV----GTP-----HYTAPEVLAHKRYGL
.   |.. .| ....| | | .|||| ...|||| . |. ..|.  . |.||||. ....      .. .  .    |.        .|||.. ....  
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KVDTYSFGIILWEMATN-QIPYRD-----KTQAEIYSHVVTHGWHLKIPSS--------VPDGLRRLILRCWSIDPNDRPDFDEIVDSF
| | .|||. .||. |. | || .     .. .|.. .| . |  ...| .         || . .....||  ||.||| | ||.. |
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQ-GYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase 94534.m00175.AA CAMK 227-468 17 7.6e-43 135.43 In-house 1-419 (425) Show / Hide
Range on Protein: 227-468
Range on HMM: 1-419/425
Sequence Identity: 17% (72 aa)

ALGTGGFGTVYRSTRISTG------------ELLAIKEVRNDRIT--------------------------MGTWASLYSEIATMAK-------LKNRYI
 ||.|.||.|.. ....|.            .  ||| .  ....                            . .....||. | |       |. . |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LELVGTHI--------------------KQPYRIIT---RFCPGK----SLFERLH-RPC-------------VPLTPLHLTQIAYQMAVGIAYLHSLGI
. |  .                      .. . ...    .|.|      ||...  ..|               .|     ..  |.. ...|.||..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDLKTLNIILDEDE----------------A-AIIADFGLCGFVDNNEG------------------------LVGGVGTPHYTA-PEVLAHKR----
||||||  || ||...                .   |.|||.  ..| .|.                        .   .|||.| | ||||  |.    
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

----------YGLKVDTYSFGIILWEMATNQIPYRDK-------------TQAEIYSHVVTHGWHLKIPS----------------------SVPDGLRR
          || |.|  | |.||  | .   |....             .. |..  . .  ..   |                        | .  . 
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LILRCWSIDPNDRPDFDEI
|| ..   ||..|.  ...
LIRKMLQVDPEKRMTIEQC

Kinase 94534.m00175.AA TK 222-472 15 5.3e-42 138.09 In-house 1-486 (486) Show / Hide
Range on Protein: 222-472
Range on HMM: 1-486/486
Sequence Identity: 15% (73 aa)

IALDDALGTGGFG---TVYRSTRISTG-------------------------ELLAIKEVRNDRITMGTWASL---------------YSEIATMA--KL
| | . || | ||   .||. . .. .                         .  |.| .. .  .  .   .                .|.. |   ..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

KNRYILELVG-THIK------------QPYRIITRFCPGKS----LFERLHRPCV---------------------------------------------
.   |. |.|  . .            .|. |.. ..|. .    | . |..                                                
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------PLTPLHLTQ-------------------IAYQMAVGIAYLHSL------GIVHRDLKTLNIILDEDEA-----------AIIADFG----
          |||  .| |                   ...| | | .||||.      ..||||| . |. ..|.             . |||||    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----LCGFVDN--NEGLVGGVGTPH-------------------------YTAPEVLA---------HKRYGLKVDTYSFGIILWEMAT-N-QIPYRDKT
    |.  ...  .   ... ||.                          ..|||.|.         ....  | | .|||. .||. |   . .| . .
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

Q---------AEIYSHVVT-------------HGWHLKIPSSVP--------------DGLRRLILRCWSIDPNDRPDFDEIVDSF
          .|.. ....             ..  .. |   |              . . .|...||. ||.|||.|..... .
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase 94534.m00175.AA TKL-ciliate1 222-472 22 6.7e-41 137.73 In-house 1-279 (279) Show / Hide
Range on Protein: 222-472
Range on HMM: 1-279/279
Sequence Identity: 22% (64 aa)

IALDDALGTGGFGTVYRSTRISTGELLAIKEVRNDRITM--GTWASLYSEIATMAKLKNRY-ILELVGTHIK-QPYRIITRFCPGKSLFERLHR-PC--V
| .    | | |. || ..| .  .  ||..   .            . || .  |.|.    ..|.|.  .   . ||. .|.. ..|. .|| .   .
ITMGQKIGSGHFCNVY-KGRCNSYD-VAIMNMNYFNSQESFINQKEFQREIQQHIKIKQHINLQQLQGISFYDNNFYIIMEHCHKGTMFDICHRKHSQIY

PLTPLHLTQIAYQMAVGIAYLHSLG--IVHRDLKTLNIILDEDEAAIIADFGLCGF-------VDNNEGL---VGGVGTPHYTAPEVLA-----HKRYGL
..  .|   . .  | |. |||..   ..||||| .|| .||.    | .|.           ...   .   ..  .|.|. |||..       . .  
MIKWQHRMRWCKDIAQGMQYLHMRQNPLIHRDLKMQNILYDEPYQYKICNFPHVKIADFHRIRNCSFQDMQNEMQRNTTFHWMAPEQMDPHIFPNYPINE

KVDTYSFGIILWEMATNQIPYRDKTQAEIYSHVVTHGW---HL---KIPSSVPDGLRRLILRCWSIDPNDRPDFDEIVDSF
|.| |..||...... .  |.  |  .   .  .  .     |   .|.   |. .  |. |||...||.||.|.|| .  
KIDIYAYGIVMYILCFRKTPFQQKMSVINIMCYWCEFPGRPNLGPQFIHFDCPQNFHNLMMRCWCQNPNKRPNFNEIIQIL

Kinase 94534.m00175.AA Dicty4-Unclassified 295-472 32 4.4e-40 134.95 In-house 79-263 (263) Show / Hide
Range on Protein: 295-472
Range on HMM: 79-263/263
Sequence Identity: 32% (60 aa)

IITRFCPGKSLFERLH-RPCVPLTPLHLTQ-----IAYQMAVGIAYLHSLGIVHRDLKTLNIILDEDEAAIIADFGLCGFVDNNEGLVGGVGTPHYTAPE
|.. | .   |||  | .|     |. |       .|   | |...||.  ..|||.|  || .| .  . |||||.   .|.|  .    |||  ..||
IVMEFMHKGNLFEVIHSKPSEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPE

VLAHKRYGLKVDTYSFGIILWEMATNQIPYRDKT-QAEIYSHVVTHGWHLKIPSSVPDGLRRLILRCWSIDPNDRPDFDEIVDSF
.| |  |  | | ||....|.|.||   || .     ..   |   .   |||....  ...||  ||. ||| || ...|..  
CLMHESYNQKSDVYSYAMMLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL

Kinase 94534.m00175.AA UTK 385-472 35 1.3e-20 67.24 In-house 206-296 (296) Show / Hide
Range on Protein: 385-472
Range on HMM: 206-296/296
Sequence Identity: 35% (32 aa)

TAPEVLAHK-RYGLKVDTYSFGIILWEMATN-QIPYRDKTQAEIYSHVVTHG-WHLKIPSSVPDGLRRLILRCWSIDPNDRPDFDEIVDSF
.|||.|.|  |. .| | .|||. .||. |. . || . . ...   |.  |  ... | ..|. . || .|||  || .||||...|. .
MAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM

Kinase 94534.m00175.AA UTK 222-366 26 4.1e-19 62.05 In-house 1-175 (296) Show / Hide
Range on Protein: 222-366
Range on HMM: 1-175/296
Sequence Identity: 26% (47 aa)

IALDDALGTGGFGTVYRSTR--IS--TGE-LLAIKEVR---NDRITMG---TWASLYSEIATMAKLK-NRYILELVGTHIK-QPYRIITRFCPGKSLFE-
..| . || | ||.|.. ..  .|   .| . |.|. .   ... ..    ..  .  |.. |....  ...| |||.. . .|  |.|..... .|   
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

-RLHRPCVP-----LTPLHLTQIAYQMAVGIAYLHSLGIVHRDLKTLNIILDED-------EAAIIADFG---LC
 | ||| .|     ||  .... |.. | | .|||| |.|||||   |. ....       . . |||||   ..
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMS

Kinase 94534.m00175.AA Dicty4 222-238 41 0.000187 10.96 In-house 1-17 (277) Show / Hide
Range on Protein: 222-238
Range on HMM: 1-17/277
Sequence Identity: 41% (7 aa)

IALDDALGTGGFGTVYR
|. .. .|.|.||.||.
INIEQRIGKGSFGEVYK