Gene 89075.m00073 (T.vaginalis)

89075.m00073

Species: T.vaginalis
Alias: TvagK0870, 89075.m00073
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag2

Sequence

Name Sequence Type Origin Length Description Download
89075.m00073.AA Protein None 836 None Fasta, JSON
89075.m00073.kin_dom Protein Kinase Domain None 248 None Fasta, JSON

Protein domain

Protein domains of 89075.m00073.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 89075.m00073.AA Fer 217-260 22 2.7e-08 24.48 In-house 239-283 (283) Show / Hide 
Range on Protein: 217-260
Range on HMM: 239-283/283
Sequence Identity: 22% (10 aa)

KLLNGFRPIFDVRAPLFIQSIME-SCWTQEPQRRPSANQVQRLFL
.  .| .. .  ..| .| .||. .||...|  ||....... . 
IIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase 89075.m00073.AA TK 230-259 26 8.9e-08 21.34 In-house 457-486 (486) Show / Hide 
Range on Protein: 230-259
Range on HMM: 457-486/486
Sequence Identity: 26% (8 aa)

APLFIQSIMESCWTQEPQRRPSANQVQRLF
.| ... .| .||  .|..||.  |... .
PPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 89075.m00073.AA TKL 171-259 15 2.9e-07 22.24 In-house 239-364 (364) Show / Hide 
Range on Protein: 171-259
Range on HMM: 239-364/364
Sequence Identity: 15% (19 aa)

FVAPEL------QTIYA----------PNFMTDMFSLSMVICRFFSQGYKFKPSHKSGSI---------GFKLLNGFRPIFD------------VRAPLF
. |||.       | ..           .  .|..|  .|..  ..    ..  . .  |             ..| ||  .              .|  
WMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPS

IQSIMESCWTQEPQRRPSANQVQRLF
. ..|. || ..|. |||....   .
MKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 89075.m00073.AA PDGFR 230-259 36 6.5e-07 17.83 In-house 329-358 (358) Show / Hide 
Range on Protein: 230-259
Range on HMM: 329-358/358
Sequence Identity: 36% (11 aa)

APLFIQSIMESCWTQEPQRRPSANQVQRLF
||  | .|| .||  .|..||.  |.  . 
APEEIYEIMQKCWDFDPEKRPTFQQLCQFL
Kinase 89075.m00073.AA RTKB 230-259 33 7.3e-07 19.19 In-house 235-264 (264) Show / Hide 
Range on Protein: 230-259
Range on HMM: 235-264/264
Sequence Identity: 33% (10 aa)

APLFIQSIMESCWTQEPQRRPSANQVQRLF
.|  .  ||  ||  |.| ||.   . ..|
MPQAADHIMQMCWQMEAQHRPDFDELVDAF
S_TKc 89075.m00073.AA S_TKc 5-260 13 2e-06 -82.65 SMART 1-231 (231) Show / Hide 
Range on Protein: 5-260
Range on HMM: 1-231/231
Sequence Identity: 13% (38 aa)

YSNVKPICEHANTKVFIATNNLDQQLEIITQISNLNLSEIDIKSFKANFNILSKLSHPAISIPYKFKILQNSLSTIFLFAKTNT-TKTMDDYLVNVTQNE
|  ...| . |  ||. .... ....  | .|.         ....   .||.|  || | . ..  .     .  . .   .. . .. ||...   . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNI-VKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----YNPEMSILFSAGVISAITYLHSNNIVCNDITFDSILIDENLFPI------FSSIGTYFLLPSLGPPSDLHDSV----FVAPELQTIYAPNF-MTDM
    ... .   . . ...|. |.||..|.  |.  . ||.||    |      .. .               .  .    ..|||.      ..   |.
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL--------------TTFCGTPWYMAPEVL---GYGKCKCDW

FSLSMVICRFFSQGYKFKPSHKSGSIGFKLLNGFRPIFDVRAPLFIQSIMESCWTQEPQRRPSANQVQR--------LFL
 |.  ..  ...    |          .....  .       | ... ... |.. .|..||.| .. .         ..
WSCGCILYEMLCGYPPFP-------QMQMMFKKIG------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 89075.m00073.AA Pkinase_Tyr 230-259 26 3e-06 21.69 Pfam 241-270 (270) Show / Hide 
Range on Protein: 230-259
Range on HMM: 241-270/270
Sequence Identity: 26% (8 aa)

APLFIQSIMESCWTQEPQRRPSANQVQRLF
.|  | ..| .|| ..|..||.  .... .
CPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 89075.m00073.AA RGC 222-261 20 5e-06 17.38 In-house 253-300 (300) Show / Hide 
Range on Protein: 222-261
Range on HMM: 253-300/300
Sequence Identity: 20% (10 aa)

FRPIFDVR-------APLFIQSIMESCWTQEPQRRPS-ANQVQRLFLS
|||  .         ..  . ..|. ||.  |  ||. ..|.. .. .
FRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase 89075.m00073.AA RGC 222-261 20 6e-06 17.38 In-house 253-300 (300) Show / Hide 
Range on Protein: 222-261
Range on HMM: 253-300/300
Sequence Identity: 20% (10 aa)

FRPIFDVR-------APLFIQSIMESCWTQEPQRRPS-ANQVQRLFLS
|||  .         ..  . ..|. ||.  |  ||. ..|.. .. .
FRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase 89075.m00073.AA LRRK 235-261 25 9e-06 16.33 In-house 325-351 (351) Show / Hide 
Range on Protein: 235-261
Range on HMM: 325-351/351
Sequence Identity: 25% (7 aa)

QSIMESCWTQEPQRRPSANQVQRLFLS
|. ...||...|..||...|.     .
QDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 89075.m00073.AA KIN6 237-259 43 1.3e-05 14.32 In-house 283-305 (305) Show / Hide 
Range on Protein: 237-259
Range on HMM: 283-305/305
Sequence Identity: 43% (10 aa)

IMESCWTQEPQRRPSANQVQRLF
|| |||   | .||  |..  .|
IMQSCWQEKPDDRPEFNEMRMQF
Kinase 89075.m00073.AA TKL-Sp1 234-259 42 3e-05 11.9 In-house 238-263 (263) Show / Hide 
Range on Protein: 234-259
Range on HMM: 238-263/263
Sequence Identity: 42% (11 aa)

IQSIMESCWTQEPQRRPSANQVQRLF
.| |.| |  |.| .|||| .    |
VQKILEPCFDQKPEKRPSAEDLLDQF
Kinase 89075.m00073.AA TKL 115-144 31 0.01889 4.65 In-house 140-177 (364) Show / Hide 
Range on Protein: 115-144
Range on HMM: 140-177/364
Sequence Identity: 31% (12 aa)

GVISAITYLHSNN--------IVCNDITFDSILIDENL
.. ... ||||.|        |.  |.. . ||.|||.
DIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENW
Kinase 89075.m00073.AA TKL-Sp1 113-133 42 0.067108 1.24 In-house 104-124 (263) Show / Hide 
Range on Protein: 113-133
Range on HMM: 104-124/263
Sequence Identity: 42% (9 aa)

SAGVISAITYLHSNNIVCNDI
| .| .|.|..|  ||   ||
SCEVLQAVTFMHACNILHLDI
Ank 89075.m00073.AA Ank 745-778 41 3.6e-07 30.1 Pfam 1-33 (33) Show / Hide 
Range on Protein: 745-778
Range on HMM: 1-33/33
Sequence Identity: 41% (14 aa)

DGKTPLMAAAESGNLELIKLLLKTKAIDQNLQME
|| |||. |...|..| .|.||. .  | |.|  
DGFTPLHLACRCGHTEVVKMLLQ-HGADVNAQDD
Ank 89075.m00073.AA Ank 677-710 38 6.3e-05 22.03 Pfam 1-33 (33) Show / Hide 
Range on Protein: 677-710
Range on HMM: 1-33/33
Sequence Identity: 38% (13 aa)

FGRTALHAAAFNGAVESLSILLSMSEIDVNRKDN
 |.|.|| |...| .| .. ||.    ||| .|.
DGFTPLHLACRCGHTEVVKMLLQ-HGADVNAQDD
Ank 89075.m00073.AA Ank 711-744 41 0.000458 18.92 Pfam 1-33 (33) Show / Hide 
Range on Protein: 711-744
Range on HMM: 1-33/33
Sequence Identity: 41% (14 aa)

FGETPFYLACERGNFFSVKQFLSDKRVDVNAANE
 |.||  |||..|.   || .|. .  |||| . 
DGFTPLHLACRCGHTEVVKMLLQ-HGADVNAQDD
Ank 89075.m00073.AA Ank 779-791 30 1.915457 5.86 Pfam 1-13 (33) Show / Hide 
Range on Protein: 779-791
Range on HMM: 1-13/33
Sequence Identity: 30% (4 aa)

NGQTAFHCAASYD
.|.|. |.|....
DGFTPLHLACRCG
Ank 89075.m00073.AA Ank 812-831 25 27.067966 1.71 Pfam 1-19 (33) Show / Hide 
Range on Protein: 812-831
Range on HMM: 1-19/33
Sequence Identity: 25% (5 aa)

KGRTAIDIAIKNGFDSSVIE
 |.|.  .|...| . .|..
DGFTPLHLACRCG-HTEVVK