84488.m00156

Species: T.vaginalis
Alias: 84488.m00156, TvagK0283
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
84488.m00156.AA Protein None 822 None Fasta, JSON
84488.m00156.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of 84488.m00156.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 84488.m00156.AA TKL 214-458 27 2.1e-83 283.39 In-house 1-364 (364) Show / Hide
Range on Protein: 214-458
Range on HMM: 1-364/364
Sequence Identity: 27% (102 aa)

IGHGYSGRVYEGYIVGRP--------EKVAIKVLNG-------------------------SDTNGAMRRSLRTEITTLSTLSHPSILKLLGYTLKSP--
|| | .| || |.  | .        . ||.|...                          ....  .|  .. ||  .| |.|| |....|| . .|  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------FCLIIELLQNGSLADFLKNRPNELTPTDKTLITIDVARGMHYIHE--------KMLIHRDLKSFNILLDSNKR--------------A
            .|.. |. ..||| ..|        .  .  . .|.||||.| |         . .||||||| |||.|.| .              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

RICDFGFVRVDSFEP---------------------STGMIGTPQWMAPEVMMCSP---------------MYDNKVDVYSFGIVLWEMLTNQPPYAGIP
 |||||. |. | .                      .   .|||.||||||.. ..                |. |.|||||||||||.|| ..||...|
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

VQRLP---------TLIVKNEYRPEIP------------EGTPPALAGLIKDCWSSDPTKRPSFAEILTKL
               ..... .||.||            . .|| .. |..|||..||.||||| ||| .|
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase 84488.m00156.AA TKL-Unique 212-458 33 5.6e-81 275.33 In-house 3-290 (290) Show / Hide
Range on Protein: 212-458
Range on HMM: 3-290/290
Sequence Identity: 33% (98 aa)

KEIGHGYSGRVYEGYIVGRPEKVAIKVLN-GSDTNGAMRRSLRTEITTLSTLS-HPSILKLLGYTL----KSP-FCLIIELLQNGSLADFLK--------
. || | .|.|| |  ..| ..||||...  .| .  |.. .. |......|  || |... ||.     . | .|.. | .. ||| | |         
NKIGEGGYGQVYKG--KWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

-NRPNELTPTDKTLITIDVARGMHYIHEKM--LIHRDLKSFNILLDSN-----KRARICDFGFVRVDS--FEPSTGMI---------GTPQWMAPEVMMC
 |. ..|..  .  . ||.|.||.|.| .    ||||||| |.|.|.|      ...|||||.... |   . .....         |...||||||.. 
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

S-PMYDNKVDVYSFGIVLWEMLTNQP------PYAGIPVQRLPTLIVK--NEYRPEIPEGTPPALAGLIKDCWSSDPTKRPSFAEILTKL
.  .|..|.|||||||||||..|..       || |.  . .  .. .   .|||.||.  |. .  ||..|| .||..|||| ||...|
NFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL

Kinase 84488.m00156.AA Dicty4 208-460 36 1.4e-76 254.98 In-house 1-277 (277) Show / Hide
Range on Protein: 208-460
Range on HMM: 1-277/277
Sequence Identity: 36% (103 aa)

IQYEKEIGHGYSGRVYEGYIVGRPEKVAIKVLNGSDTN--GAMRRSLRTEITTLSTLSHPSILKLLGYTL----KSPFCLII-ELLQNGSLADFLKNRPN
|. |..|| |  | || |    |  .||.|.||   .|   .|  ..| |.. .. ..|| |....|. .    ... ..|  |..  |.|.  | ..| 
INIEQRIGKGSFGEVYKGTW--RGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPS

ELTPTDKTL---------ITIDVARGMHYIHE--KMLIHRDLKSFNILLDSNKRARICDFGFVR----VDSFEP-STGMIGTPQWMAPEVMMCSPMYDNK
|  . .|           . .|.|||| . |.     ||||||| |.| | |.|. .||||. .    . ..    ....||| ||||||||  | |. |
EQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQP-YNEK

VDVYSFGIVLWEMLTNQPPYA--GIPVQRLPTLIVKNEYRPEIPEGTPPALAGLIKDCWSSDPTKRPSFAEILTK--LYD
.|||||||||||.|| | ||.  ..|   .  ...    ||.||  .|| .. ||..||. ||..||||.||. .  |  
ADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH

Kinase 84488.m00156.AA MLK 208-458 31 2.3e-75 256.68 In-house 1-291 (291) Show / Hide
Range on Protein: 208-458
Range on HMM: 1-291/291
Sequence Identity: 31% (93 aa)

IQYEKEIGHGYSGRVYEGYIVGRP---EKVAIKVLN----GSDTNGAMRRSLRTEITTLSTLSHPS----ILKLLGYTLKS-P-FCLIIELLQNGSLADF
|| .. ||.| .| |. |.  ..      ||.|  .     .   .. .. ...|.  |. ||||     | ...|  |.. . ||.. | ...|||...
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LKNRPN-------------ELTPTDKTLITIDVARGMHYIHE-K--MLIHRDLKSFNILLDS------NKRARICDFGFVR-VDSFEPS--TGMIGTPQW
|.....               ..  .  .  ..|||||| |. .  ..||||||| |||.|       .. ..||||| .| . . . .  ....||. |
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYAW

MAPEVM--MCSPMYDNKVDVYSFGIVLWEMLTNQPPYA-GIPVQRLPTLIVKNEYRPEIPEGTPPALAGLIKDCWSSDPTKRPSFAEILTKL
|||||     . .|. |.||.|.|.||||||| . ||. ..   .    .. |. || || . |. .. |.|.||..|| |||||..|...|
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL

Kinase 84488.m00156.AA LRRK 208-460 28 7.6e-71 241.68 In-house 1-351 (351) Show / Hide
Range on Protein: 208-460
Range on HMM: 1-351/351
Sequence Identity: 28% (102 aa)

IQYEKEIGHGYSG-RVYEGYIVG-------------RP-------------EKVAIKVLNG----------SDTN--------------------GAMR-
. .|..|| | .| .|| .   |              |             ..||||..|           . .|                    ...| 
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

-RSLRTEITTLSTLSHPSILKLLGYTLKSPFCLIIELLQNGSLADFLKNRPN--------ELTPTDKTLITIDVARGMHYIHEKM--LIHRDLKSFNILL
 |..| |.. .|.| ||.|..|.|... .|.|.. |....|.| .||.|. .        ..... |  | ...|.|| | | ..  .||||||| ||||
FREFRHEVWIMSHLNHPNIVSLKGFCI-HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILL

DSNK------------RARICDFGFVR-VDSFEP--STGMIGTPQWMAPEVMMCS--PMYDNKVDVYSFGIVLWEMLTNQ-PPYAGIP-V-----QRLPT
 | .             | |.|||  |   .| .    |. |.|.|||||.|       |. |||.||||..||| || | .|. ... .     . .  
WSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIE

LIVKNEYRPEIPEG-TPP-----ALAGLIKDCWSSDPTKRPSFAEILTKLYD
.....  || ||.   ||      .  ||..||. ||.|||.| .|. .| .
DKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ

Kinase 84488.m00156.AA Pkinase_Tyr 208-458 30 9.8e-71 240.18 Pfam 1-270 (270) Show / Hide
Range on Protein: 208-458
Range on HMM: 1-270/270
Sequence Identity: 30% (84 aa)

IQYEKEIGHGYSGRVYEGYIV----GRPEKVAIKVLNGSDTNGA-MRRSLRTEITTLSTL-SHPSILKLLGYTL--KSP--FCLIIELLQNGSLADFLKN
|.  |..|.|  |.||.|.      .   .||.|.|. . .  . .|...  |. ....| .|| |..|.|  .  . |   ... |. ..|.| |.|..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

R---PNELTPTDKTLITIDVARGMHYIHEKMLIHRDLKSFNILLDSNKRARICDFGFVR-V-----DSFEPSTGMIGTPQWMAPEVMMCSPMYDNKVDVY
.   .. ||. |.  . ...|.|| | ..| .|||||   |.|...|. ..|||||  | .       .  ..|      |||||... .  .  | ||.
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGK-FTTKSDVW

SFGIVLWEMLT-NQPP-YAGIPVQRLPTLIVKNEYRPEIPEGTPPALAGLIKDCWSSDPTKRPSFAEILTKL
|||...||..|  . | |.|.. ...  .| .. || ..||..|. .  |.|.||  || .||.|.||. .|
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase 84488.m00156.AA TK 208-458 15 5.6e-70 233.54 In-house 1-486 (486) Show / Hide
Range on Protein: 208-458
Range on HMM: 1-486/486
Sequence Identity: 15% (77 aa)

IQYEKEIGHGYSG---RVYEGYIVGRP-------------------------EKVAIKVLNGSDTNGAMRRSL---------------RTEITTLST--L
|...|..|.|  |   .||.|   ||.                         ..||.|.|   |.. .... .                 |.  ..   .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

SHPSILKLLGYTLKS-------------PFCLIIELLQNGS----LADFLKNRPNE--------------------------------------------
 || |..|.|. ...             |.... |. ..|.    | |.|......                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LTPTDKTLITIDVARGMHYIHEK------MLIHRDLKSFNILLDSNKR-----------ARICDFG---
                               ||. ..  .  ..|.|| |.|.|       ..||||   |.|...|..           ..|.|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----FVRVDSFEPSTGMIGTPQ----------------------------WMAPEVMMCSP--------MYDNKVDVYSFGIVLWEMLT-N-QPPYAGI
       | .  .      ...                             |||||...            .  | ||.|||...||..|   .|.| |.
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

PV---------QRLPTLIVKN-------------EYRPEIPEGTP--------------PALAGLIKDCWSSDPTKRPSFAEILTKL
.          | .  ....               .|.. |.. |              .... |...||. || .||.|.... .|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase 84488.m00156.AA TyrKc 208-458 28 2.8e-66 227.41 SMART 1-280 (280) Show / Hide
Range on Protein: 208-458
Range on HMM: 1-280/280
Sequence Identity: 28% (83 aa)

IQYEKEIGHGYSGRVYEGYIVGRPEKVAIKVLNGSDTNGAMRRSLRTEITTLSTL--SHPSILKLLGYTLK--------SPFCLIIELLQNGSLADFLKN
|. .|..|.|  |.||.|      ..||.|.|. .      |. .. |.  .. |  .|| |..|.|. ..         | ... |.  .|.| |.|..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

RPNELTPTDKTLITIDVARGMHYIHEKMLIHRDLKSFNILLDSNKRARICDFGFVRVDSFE------PSTGMI----GTPQ-----WMAPEVMMCSPMYD
. ..|.. |.  . ...|.|| |.|.| .|||||   |.|...|....|.|||  |    .       .. .     |.       |||||..    .. 
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFT

NKVDVYSFGIVLWEMLTN-QPPYAG-----IPVQRLPTLIVKNEYRPEIPEG--------TPPALAGLIKDCWSSDPTKRPSFAEILTKL
 | ||.|||...||..|. |.|| |     .. |..  . ||. ||...|.          |...  ..|.||  || .||.|.||  ..
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEY-VKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase 84488.m00156.AA Dicty4-Unclassified 208-458 31 3.7e-63 215.13 In-house 1-263 (263) Show / Hide
Range on Protein: 208-458
Range on HMM: 1-263/263
Sequence Identity: 31% (85 aa)

IQYEKEIGHGYSGRVYEGYIVGRPEKVAIKVLN-GSDTNG-AMRRSLRTEITTLSTLSHPSILKLLGYTLKSP------FCLIIELLQNGSLADFLK---
||  ..|| |   .|. |   |.   ||.| .| ...     |    . |.  |  ..||  .|. || .  |      .| . |..  | |        
IQIDQFIGKGHFSKVHKGNWKGK--DVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCI-NPRSHKSTMCIVMEFMHKGNLFEVIHSKP

---NRPNELTPTDKTLITIDVARGMHYIHEKMLIHRDLKSFNILLDSNKRARICDFGFVRVDSFEPSTGMIG-TPQWMAPEVMMCSPMYDNKVDVYSFGI
   ..|  |  |    . .|.|.|| . | . .||||.|| |||.| .  ..| |||  || .|      |. || | .||..|    |  | ||||...
SEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHE-SYNQKSDVYSYAM

VLWEMLTNQPPYAGIP-VQRLPTLIVKNEYRPEIPEGTPPALAGLIKDCWSSDPTKRPSFAEILTKL
.|.|..|   || .|. .  .  ..     ||.||.  .. .  |||.||. || |||.. .|  .|
MLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL

Kinase 84488.m00156.AA Pkinase 208-458 26 2.4e-62 218.21 Pfam 1-293 (293) Show / Hide
Range on Protein: 208-458
Range on HMM: 1-293/293
Sequence Identity: 26% (77 aa)

IQYEKEIGHGYSGRVYEGYIVGRPEKVAIKVLNGSDTNGAMRRSLRT--EITTLSTLSHPSILKLLGYTL-KSPFCLIIELLQNG----SLADFLK-NRP
.. .. || | .|.||... .| ...||.|... ....  .....|   ||  .  |.|| |..|...   |.  ... |....|    .|.|...  | 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NEL--TPTDKTLITIDVARGMHYIHEKMLIHRDLKSFNILLDSNKRA----RICDFGFVR---VDSFEPSTGMIGTPQWMAPEVMMCSPMYDNKVDVYSF
. .  .. .   .   ..||. |.|..  ||||||. |||.|.|       .|||||. .     . .  |.  ||| .||||| . ...|. |||..|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GIVLWEMLTNQPPYAGI----PVQRLPTLIVKNEY-RPEIPEGTP---------------------PALAGLIKDCWSSDPTKRPSFAEILTK--L
|..|.|||. .||. |     .  .   .|... . ... .. ..                     ...  .||.|.  ||.|||....||    .
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 84488.m00156.AA S_TKc 208-459 27 2.2e-60 207.86 SMART 1-231 (231) Show / Hide
Range on Protein: 208-459
Range on HMM: 1-231/231
Sequence Identity: 27% (75 aa)

IQYEKEIGHGYSGRVYEGYIVGRPEKVAIKVLNGSDTNGAMRRSLRTEITTLSTLSHPSILKLLGYTLKSPFCLIIELLQN--GSLADFLKNRPNE----
 .  ..||.|  |.|| .. ..  ..||||...         ...| ||  |.   || | ||...   . .... |.. .  |.| |..|.|. .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LTPTDKTLITIDVARGMHYIHEKMLIHRDLKSFNILLDSNKRARICDFGFVRVDSFEPSTGMIGTPQWMAPEVMMCSPMYDN-KVDVYSFGIVLWEMLT
 ... .   ..  ..... |.|..  ||||||  |||||.  .  |||||. |.      | ..||| .|||||.     |.  |.|..|.|..|.|||.
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLC

NQPPYAGIPVQRLPTLIVKNEYRPEIPEGTPPALAGLIKDCWSSDPTKRPSFAEILT--------KLY
 .||.        . .. |.          .| .  .|. |.  ||.|||.  |.|.           
GYPPFP------QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 84488.m00156.AA Dicty5 208-462 36 1.9e-58 199.81 In-house 1-260 (260) Show / Hide
Range on Protein: 208-462
Range on HMM: 1-260/260
Sequence Identity: 36% (98 aa)

IQYEKEIGHGYSGRVYEGYIVGRPEKVAIKVLNGSDT-NGAMRRSLRTEITTLSTLS--HPSILKLLG---YTLKSPFCLIIELLQNGSLADFLKNRPN-
.   . |  | ||||| |   |.   |||||. ...   .    .   |.| .|     || . . .|   |  | || .  |. .|||| . |. . . 
VSFHDWIASGASGRVYNGIYKGM--DVAIKVY-SQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHV-TEYCHNGSLFNYLNDQRKT

---ELTPTDKTLITIDVARGMHYIHEKMLIHRDLKSFNILLDSNKRARICDFGFVR-VDSFEPSTGMIGTPQWMAPEVMMCSPMYDNKVDVYSFGIVLWE
    .    .  . ||.|..| ..| .  ||||||| |.|.  |  . | |||  | ||     |  .||. |||.|.    | |..|.|||||||||||
TGQPIAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQP-YHQKCDVYSFGIVLWE

MLTNQPPYAGIPVQRLPTLIVKNEYRPEIPEGTPPALAGLIKDCWSSDPTKRPSFAEILTKLYDPX
|.|   ||  |     | .. | | ||.||   |   . ||| ||   | .|||| ||.  .    
MFTRKEPYDNINNWNIPVMVMKGE-RPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII

Kinase 84488.m00156.AA TK-Unique 208-458 26 5e-56 191.67 In-house 1-294 (294) Show / Hide
Range on Protein: 208-458
Range on HMM: 1-294/294
Sequence Identity: 26% (80 aa)

IQYEKEIGHGYSGRVYEGYIVGRP-----EKVAIKVLNGSDTNGAMRRSLRTEITTLSTLS-HPSILKLLGYTL-KS-PFCLIIELLQNGSLADFLK-NR
.  ...|| |  | |. | ..|..      |... ...  . ..  .. .  ||  .. |  || |...||..  .. |...|.| ...|.| ..|. .|
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

PN------------------------ELTPTDKTLITIDVARGMHYIHE--KMLIHRDLKSFNILLDSNKRARICDFGFVR--------VDSFEPSTGMI
|.                        ...| |   . ...|.|| |...  |. .|||| . |.|| ..|.. |||||. |        . . . .. .|
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

GTPQWMAPEVMM--CSPMYDNKVDVYSFGIVLWEMLTN-QPPYAGIPVQRLPTLIVKNEYRPEIPEGT-PPALAGLIKDCWSSDPTKRPSFAEILTKL
    |||||..     . .  | ||.|||...||..|. ..|| |.|  .. ..| .. ||.. ||.  ....  |.| ||...|..||||..|. .|
---RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECI-RDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL

Kinase 84488.m00156.AA STE 210-459 22 9.4e-55 188.22 In-house 1-359 (359) Show / Hide
Range on Protein: 210-459
Range on HMM: 1-359/359
Sequence Identity: 22% (81 aa)

YEK--EIGHGYSGRVYEGYIV------GRPEK---------VAIKVLN---------------GSDTNGAMRRSLRTEITTLSTLS--HPSILKLLGYTL
.|.  .||.| .| || .. .         |.         .|||..|                ...|   . ..  || ... ..  || | | .|. .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

KSP--------FCLIIELLQNGSLADFLK---NRPNELTPT--------DKTL--ITIDVARG-MHYIHEKMLIHRDLKSFNILLDSNKRARICDFGFVR
|           ... |.. .||| |..|    ....|.           . .  |. .. .| ..|.|..  ||||.|. ||||     . .||||.  
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

--VDS----------------FEPSTGMIGTPQWMAPEVMMC-----SPMYDNKVDVYSFGIVLWEMLTNQPPYAGIPVQRLPTLIVKN-----------
  .||                 . .. ..||| ||||||...     .. || |.|..|.|....||.| .||..  .  |   .| .|           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---EYRPEIPEGTP-------------------PALAGLIKDCWSSDPTKRPSFAEILT---KLY
   .  | .|. .                    | .   |. |   || |||.  . |    .  
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI