93444.m00159

Species: T.vaginalis
Alias: 93444.m00159, TvagK0784
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
93444.m00159.AA Protein None 201 None Fasta, JSON
93444.m00159.kin_dom Protein Kinase Domain None 139 None Fasta, JSON

Protein domain

Protein domains of 93444.m00159.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 93444.m00159.AA Ciliate-E2-Unclassified 29-149 20 4e-16 52.44 In-house 100-272 (352) Show / Hide
Range on Protein: 29-149
Range on HMM: 100-272/352
Sequence Identity: 20% (36 aa)

MDYIPGVTLESLLRN---------------HKRIRL-----------LYILEIITALNLQLKKMGEKGIKHRDLKPGNIVIDAD---FVPHILDWDDVT-
|.|..| .|.  ...               ..| ..            |. .|. .|.   .|   ..| |||.|| ||..| .   . . | |.     
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHK---NNIIHRDIKPENILFDNNGKNYYIKIIDFGISKK

------------TGVSMTQSPYH----GTIRFA----APEIFEM-KKE----CASDIFSFGGIIFNMLTGKAPFDD
            .  .....       ||...     |||...  . .     ..||.|.| |.. ||.|. ||.|
YQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYD

Kinase 93444.m00159.AA Ciliate-E2 29-198 18 9.7e-15 47.0 In-house 113-304 (365) Show / Hide
Range on Protein: 29-198
Range on HMM: 113-304/365
Sequence Identity: 18% (44 aa)

MDYIPGVTLESLLRNHKRIRL------LYILEIITA-LNLQLKK-------------------MGEKG-IKHRDLKPGNIVIDADFVPHILDWD------
|.|. | .|.....|.|  |.      .|. |   . .  |. .                   . .|. | |||.|| ||..     . | |.       
MEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYD

---------------------DVTTGVS------MTQSPYHGTIRFAAPEIFEMKKE----------CASDIFSFGGIIFNMLTGKAPFDDVYNNLDYIF
                     ..|.| .      ...  . ||  . ||||...||.           ..||.|.| |.. ||.|| ||           
DDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF-----------

HFIPEEYDVEDVDEQEEDEYEQEDDEDKEKKVKKINKKNK
                                 ...|..|
--------------------------------QQQIKQCK

Kinase 93444.m00159.AA CAMK 68-166 16 1.2e-10 29.82 In-house 197-372 (425) Show / Hide
Range on Protein: 68-166
Range on HMM: 197-372/425
Sequence Identity: 16% (29 aa)

EKGIKHRDLKPGNIVIDAD-----------------FVPHILDWDDVTTGVS-------------------------MTQSPYHGTIRFAA-PEIFEMK-
...| |||||| || .| .                 .   | |.   .   .                            . . ||  ..| ||... | 
SHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKG

--------------KECASDIFSFGGIIFNMLTGKAPFDDVY-------------------NNLDYIFHFIPEEYD
                 ..|. | | | . ||.|. ||.. .                   . .   ..|.|.. .
HCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFS

Kinase 93444.m00159.AA Pkinase 68-149 30 4.3e-10 36.78 Pfam 126-214 (293) Show / Hide
Range on Protein: 68-149
Range on HMM: 126-214/293
Sequence Identity: 30% (28 aa)

EKGIKHRDLKPGNIVIDADFVP----HILDWDDVT---TGVSMTQSPYHGTIRFAAPEI--FEMKKECASDIFSFGGIIFNMLTGKAPFDD
..|| |||||| || || . ..    .| |.       .  .   . . ||....|||.  .  .   ..|..|.| |.. ||.|. ||..
SMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPG

Kinase 93444.m00159.AA TKL 69-170 17 2.7e-08 25.97 In-house 159-310 (364) Show / Hide
Range on Protein: 69-170
Range on HMM: 159-310/364
Sequence Identity: 17% (27 aa)

KGIKHRDLKPGNIVIDADFV--------------PHILDWDDVTTGVSMTQSPY---------------------HGTIRFAAPEIFEMK--KECAS---
..| |||||. || .| ..               . | |    ..   ....                        ||.|. |||.....   ....   
PPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGID

------------DIFSFGGIIFNMLTGKAPFDDVYNNLDYIFHFIPEEYDVEDV
            |..||| ... .||.. |..|  ..  ....   .| . . |
EFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQD-P-FEEMFMMV

Kinase 93444.m00159.AA CAMK-Tt 108-151 41 4e-08 23.6 In-house 297-342 (396) Show / Hide
Range on Protein: 108-151
Range on HMM: 297-342/396
Sequence Identity: 41% (19 aa)

YHGTIRFAAPEIFEMKK--ECASDIFSFGGIIFNMLTGKAPFDDVY
| ||. | |||||.         |. | | | . || |. ||.  |
YTGTVAFSAPEIFNEDCCYDETIDMWSAGCILYTMLCGQEPFQAEY

S_TKc 93444.m00159.AA S_TKc 1-200 17 5.1e-08 -59.28 SMART 16-220 (231) Show / Hide
Range on Protein: 1-200
Range on HMM: 16-220/231
Sequence Identity: 17% (42 aa)

MEGFKIP--------------------LA------PKFFDTSVKHPGEPFDWVLMDYIPG--VTLESLLRNHKR------IRLLYILEIITALNLQLKKM
. . ..                     |        |..|. .      . .. |.|..|   .| .......|      .    .  ..  . . |. .
YKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQD----DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYC

GEKGIKHRDLKPGNIVIDADFVPHILDWDDVTTGVSMTQSPYHGTIRFAAPEIFEMKKEC-ASDIFSFGGIIFNMLTGKAPFDDVYNNLDYIFHFIPEEY
 ..|| |||||| || .|   .  | |    .       . . ||  . |||..  .  . ..|. |.| |.. ||.|. ||.    ... .|. |    
HSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG---

DVEDVDEQEEDEYEQEDDEDKEKKVKKINKKNKK--------R
                ..| |.  ..|. .|. .        .
----------------SPEAKD-FIRKCLQKDPEKRPTAEALQ

Kinase 93444.m00159.AA MSK 107-147 31 4.4e-07 19.99 In-house 164-210 (277) Show / Hide
Range on Protein: 107-147
Range on HMM: 164-210/277
Sequence Identity: 31% (15 aa)

PYHGTIRFAAPEIFEM---KKE---CASDIFSFGGIIFNMLTGKAPF
.. .|. ..|||. .    ...    | |..| | | . ||||. ||
SPCFTLHYMAPEMLRRGYAQDGGYDEACDWWSLGVILYTMLTGQVPF

Kinase 93444.m00159.AA RIPK 100-158 25 2e-06 18.23 In-house 174-239 (290) Show / Hide
Range on Protein: 100-158
Range on HMM: 174-239/290
Sequence Identity: 25% (17 aa)

GVSMTQSPYHGTIRFAAPEIFE--MKKE-----CASDIFSFGGIIFNMLTGKAPFDDVYNNLDYIF
. ||.  .  ||. . .|| |.   ||       ..|. ||. ...  ||.| |. |. . . ...
VYSMKSKNRWGTLSYMPPEHFRTDNKKPIKVVTPKYDVYSFAIVMWEVLTQKHPYEDRKCMMMIMM

Kinase 93444.m00159.AA CAMKL 110-161 33 7e-06 14.59 In-house 195-255 (297) Show / Hide
Range on Protein: 110-161
Range on HMM: 195-255/297
Sequence Identity: 33% (21 aa)

GTIRFAAPEIFEM--KKEC--ASDIFSFGGIIFNMLTGKAPFDDVYN------NLDYIFHFI
|.  ..|||||.   |. .  . || | | | ..|..|. ||||  .      |  | .. |
GSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKI

Kinase 93444.m00159.AA AGC 110-149 36 1e-05 9.19 In-house 267-307 (395) Show / Hide
Range on Protein: 110-149
Range on HMM: 267-307/395
Sequence Identity: 36% (16 aa)

G--TIRFAAPEIFEMKKECASDIFS--FGGIIFNMLTGKAPFDD
|  |  . ||||.      | |. |  .| ... ||||. || .
GPCTPEYMAPEIL---YGKACDWWSFGLGCLMYEMLTGYPPFYG

Kinase 93444.m00159.AA Ciliate-E2b 28-86 24 1.6e-05 12.94 In-house 78-138 (272) Show / Hide
Range on Protein: 28-86
Range on HMM: 78-138/272
Sequence Identity: 24% (15 aa)

LMDYIPGVTLESLLRNHK--RIRLLYILEIITALNLQLKKMGEKGIKHRDLKPGNIVIDAD
.|... |  |....|. .   .     . .|  . | |.   ...| .||.|| || .| .
MMEFCNGMELFDVIREIGRLLLSTYDSQFYIASICLCLEYLHNQNIIYRDIKPENIMVDHK

Kinase 93444.m00159.AA AGC 68-86 57 3.8e-05 7.68 In-house 171-191 (395) Show / Hide
Range on Protein: 68-86
Range on HMM: 171-191/395
Sequence Identity: 57% (12 aa)

E-KGIKHRD-LKPGNIVIDAD
. .|| ||| ||| ||..|.|
SHMGIIHRDYLKPENILLDED

Kinase 93444.m00159.AA Ciliate-E2b 110-166 26 7.3e-05 10.89 In-house 167-229 (272) Show / Hide
Range on Protein: 110-166
Range on HMM: 167-229/272
Sequence Identity: 26% (17 aa)

GTIRFAAPEIFE-----MKK-ECASDIFSFGGIIFNMLTGKAPFDDVYNNLDYIFHFIPEEYD
||  . |||| .      |   ...||.|.| . . .. |. |..    .   |  .| ..||
GTPHYMAPEIIQSLQPGGKGYTYKVDIWSVGICLYEFMCGYVPWAEDVQDPYEIYQEIIKKYD

Kinase 93444.m00159.AA APH 37-100 22 0.000205 15.94 Pfam 134-205 (248) Show / Hide
Range on Protein: 37-100
Range on HMM: 134-205/248
Sequence Identity: 22% (16 aa)

LESLLRNHKRIRLLY---ILEIITALNLQLKKMGE-KGIKHRDLKPGNIVID--ADFVPH--ILDWDDVTTG
|.. .|..   ...    .....  |  .|...    .. |.|..|||...|  .|  .   ..||||.. |
LMDWCRCWVDPEWFDEDRQWWLWQRLWAWLEAHWPPPCWCHGDFHPGNVMWDPRPDGGRVTGVIDWDDACWG

Kinase 93444.m00159.AA CAMKL 68-86 52 0.000234 9.65 In-house 145-163 (297) Show / Hide
Range on Protein: 68-86
Range on HMM: 145-163/297
Sequence Identity: 52% (10 aa)

EKGIKHRDLKPGNIVIDAD
..|| |||.|| || .| .
SHGIVHRDIKPENILLDEN

Kinase 93444.m00159.AA RIPK 73-87 66 0.000351 10.11 In-house 132-146 (290) Show / Hide
Range on Protein: 73-87
Range on HMM: 132-146/290
Sequence Identity: 66% (10 aa)

HRDLKPGNIVIDADF
||||||.|| .|..|
HRDLKPENILVDNNF

Kinase 93444.m00159.AA MSK 26-81 33 0.005238 6.0 In-house 77-132 (277) Show / Hide
Range on Protein: 26-81
Range on HMM: 77-132/277
Sequence Identity: 33% (19 aa)

WVLMDYIPGVTLESLLRNHKRIRLLYILEIITALNLQLKKMGEKGIKHRDLKPGNI
.  |.|. |  |   .|  .. ..    .|.  | . .. | .||| |||||| ||
YLVMEYCNGGELFTHIRKREHFDESECRMIMRELVMAVDHMHQKGIIHRDLKPENI

Kinase 93444.m00159.AA CAMK-Tt 66-86 52 0.038886 2.5 In-house 240-260 (396) Show / Hide
Range on Protein: 66-86
Range on HMM: 240-260/396
Sequence Identity: 52% (11 aa)

MGEKGIKHRDLKPGNIVIDAD
| |. . |||||| ||  . |
MHENYVCHRDLKPNNILCNED