Gene 90417.m00127 (T.vaginalis)
90417.m00127
Species: T.vaginalis
Alias: 90417.m00127, TvagK0924
External Links:
Annotation:
Group:
CAMK
Family:
CAMK-Tvag2
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 90417.m00127.AA | Protein | None | 211 | None | Fasta, JSON |
| 90417.m00127.kin_dom | Protein Kinase Domain | None | 174 | None | Fasta, JSON |
Protein domains of 90417.m00127.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 90417.m00127.AA | CAMK | 11-186 | 21 | 6.1e-46 | 145.58 | In-house | 155-425 (425) | Show / Hide |
Range on Protein: 11-186
Range on HMM: 155-425/425
Sequence Identity: 21% (58 aa)
ITKQPE---------------LTIYDAVRFLDQIGSALQYMHENGYVHRDIKPQNVLIFDT------------------TFALCDFSVSAKLHD------
|.... .| .| |. || ||..|.|... ||||.|| |.|. | . ..|| ..|. .
IVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFM
-----------------PNELLSGEIGTSFFMA-PQVANQ-------------EQYKPKPADMWSLGVTTYVLIYGTYPYDLQ---KIYDTSGQDMVKNN
...... || .|| | | |. ..| ....||||.|| .|.. |..|.. |.. . . ...|
CSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICE-D-E-WIGMN
ISRIQPL---GDLTFPDYPILP----------------------KDLKDILRGLLDKDPDKRMTAAELVNHPFI
.... |. .||.... | .. || .|..| .||.||||... |||..
DYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | 90417.m00127.AA | Ciliate-E2 | 11-186 | 19 | 2.9e-45 | 153.3 | In-house | 138-365 (365) | Show / Hide |
Range on Protein: 11-186
Range on HMM: 138-365/365
Sequence Identity: 19% (50 aa)
ITKQPELTIYDAVRFLDQIGS---------------ALQYMHENG-YVHRDIKPQNVLIFDTTFALCDFSVSAKLHDP----------NELLSGE-----
. . .|.. . .. || . ||.|.|... .||||||.|.|. ..|| | |..|. ....
K-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSR
-----------------IGTSFFMAPQVANQEQY--------KPKPADMWSLGVTTYVLIYGTYPYDLQKIYDTSGQDMVKNNISRIQPLGDLTFP----
.|| .|||.. | ..| . .|.|||||. | ...| .|. ... ... ||
TPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF------------------QQQIKQCKIDFPCPEW
------------DYPILPKDLKDILRG----LLDKDPDKRMT-AAELVNHPFI
.. .... ||... .|.|||.||.| . .. |||..
QKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
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| Kinase | 90417.m00127.AA | CAMKL | 11-186 | 28 | 5.4e-44 | 138.19 | In-house | 114-297 (297) | Show / Hide |
Range on Protein: 11-186 Range on HMM: 114-297/297 Sequence Identity: 28% (54 aa) ITKQPE----LTIYDAVRFLDQIGSALQYMHENGYVHRDIKPQNVLIF-DT--TFALCDFSVSAKLHD----PNELLSGEIGTSFFMAPQVANQ--EQYK | |... .. .| |. || ||..|.|..| ||||||| |.|. . . ..|| |.. . |...|. |. .||| . . ..| IVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYD PKPADMWSLGVTTYVLIYGTYPYDLQKIYDTSGQDMVKNNISRIQPLGDLTFPDYPILPKDLKDILRGLLDKDPDKRMTAAELVNHPFI ...|.||.||. |....|..| | . . . |.| . . ... | .| .. .. |..|..|..| ..|.||.|. ...|||. GPKVDIWSCGVILYAMVCGYLPFDDDTYN-KQGKDNI--YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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| Kinase | 90417.m00127.AA | ULK | 22-186 | 26 | 1.6e-40 | 139.18 | In-house | 132-329 (329) | Show / Hide |
Range on Protein: 22-186 Range on HMM: 132-329/329 Sequence Identity: 26% (52 aa) AVRFLDQIGSALQYMHENGYVHRDIKPQNVLIFDTTFA-------------LCDFSVSAKLHDP---NELLSGEI------GTSFFMAPQVAN----QEQ |. |. || ......|.....||||||||.|| . . ..|| . .. .. .... || .||||. . |.. AIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKP YKPKPADMWSLGVTTYVLIYGTYPYDLQKIYDTSGQDMVKNNISRIQPL-----GDLTFPDY---PILPKDLKDILRGLLDKDPDKRMTAAELVNHPFI | . .|.||||. | ..|| .|. . ..|. | . |. . . | ||.. |.. ...||..|..| .|...|.. || |||.. YYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF |
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| Kinase | 90417.m00127.AA | Pkinase | 11-186 | 25 | 2.4e-37 | 133.1 | Pfam | 95-293 (293) | Show / Hide |
Range on Protein: 11-186 Range on HMM: 95-293/293 Sequence Identity: 25% (52 aa) IT--KQPEL--TIYDAVRFLDQIGSALQYMHENGYVHRDIKPQNVLIF-DTTF----ALCDFSVSAKL-HDPNELLSGEIGTSFFMAPQVANQEQYKPKP |. .. . . .. ... || ..|.|.|..| .|||.||.|.|| . . .||| ..... . .|. ... ||...||| | . || ... ISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK ADMWSLGVTTYVLIYGTYPYDLQKIYDTSGQDMVKNNISRIQPLGDLTFPDYPILP-------------------KDLKDILRGLLDKDPDKRMTAAELV .||||.|.. | .. | |.. ... .. . . . | || . ..| |. . . ...||.....|.||| || ||.... VDMWSCGCILYEMLCGRPPFP-GHC-WHDN-HDQMQMICRIMG-PPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQIL NHPFI .||.. QHPWF |
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| Kinase | 90417.m00127.AA | Ciliate-E2-Unclassified | 11-186 | 21 | 2e-36 | 123.84 | In-house | 112-352 (352) | Show / Hide |
Range on Protein: 11-186
Range on HMM: 112-352/352
Sequence Identity: 21% (53 aa)
ITKQPE-----------------LTIYDAV-----RFLDQIGSALQYMHENG-YVHRDIKPQNVLIFDT----TFALCDFSVSAKLHDP-----------
|.|.. .| . |. ... || ..|.|.|... .||||||.|.|. . ..||. | |. ..
IKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKM
----NELLSGEIGTSFFM----APQVANQEQYKP---KPADMWSLGVTTYVLIYGTYPYD--LQKIYDTSGQDMVKN-----NISRIQPLGDLTFPDYP-
..... .|| .| || | ...| . .|.||||| | ...|.||.. ....... . . | .. ... ... || .|
QIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWI-NNAYRKQLYQNIKQKNIQFPKFPW
-----ILPKDLKDILR----GLLDKDPDKRMTAAELVNHPFI
.... ||... .|.|.|.||.|. .. |||..
QQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
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| Kinase | 90417.m00127.AA | CAMKK-Unclassified | 32-186 | 25 | 1.7e-35 | 112.87 | In-house | 190-392 (392) | Show / Hide |
Range on Protein: 32-186
Range on HMM: 190-392/392
Sequence Identity: 25% (55 aa)
ALQYMHENG---------------------YVHRDIKPQNVLIFDT-T-----FALCDFSVSAKLHDPNEL-LSGEIGTSFFMAPQVANQE--QYKPKP-
.||||| .. .|||||||| || . . | ..||..| .. . .. |.. ||. |||| . | |...
GLQYMHNFNQACSYIIIYINEFDKIDHFQDIIHRDIKPQNILIDHEDNDKGEHFKIADFGISVIMEHEQQKKLKNNAGTYCFMAPEFWSKENFKYDYNDY
------------------------ADMWSLGVTTYVLIYGTYPY---DLQKIYDTSGQDMVKNNISRIQPLGDLTFPD--YPILPKDLKDILRGLLDKDP
||.|||||| | ..|.. |. .||.. | .. . . || | .. .|| . ...||.|
SFLPGTFNPLRKTYRIERICFYKKADIWSLGVTFYCMVYHSLPFWHKNLQELFH----QMICQKE--------INFPPQYHPHCSHEFKDLIQKMCDKNP
DKRMTAAELVNHPFI
.|| |. . .||..
KKRITIDQMLVHPWF
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| Kinase | 90417.m00127.AA | ULK | 22-186 | 25 | 2.6e-35 | 122.74 | In-house | 128-324 (324) | Show / Hide |
Range on Protein: 22-186 Range on HMM: 128-324/324 Sequence Identity: 25% (52 aa) AVRFLDQIGSALQYMHENGYVHRDIKPQNVLIFDTTFA-------------LCDFSVSAKLHDPN---ELLSGEI------GTSFFMAPQVAN----QEQ |. |. || ......|.....|||||||| || . . ..|| . .. ..| .. || .||||. . |.. AIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKP YKPKPADMWSLGVTTYVLIYGTYPYDLQKIYDTSGQ--DMVKN------NISRIQPLGDLTFPDYP---ILPKDLKDILRGLLDKDPDKRMTAAELVNHP | . .|.||||. | ..|| ||. . ..|. . ....| | . . ||..| .. ...||..|..| .|...|.. |. ||| YYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQP----IQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHP FI .. WF |
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| Kinase | 90417.m00127.AA | STE | 32-186 | 24 | 6.1e-27 | 92.23 | In-house | 163-359 (359) | Show / Hide |
Range on Protein: 32-186 Range on HMM: 163-359/359 Sequence Identity: 24% (53 aa) A-LQYMHENGYVHRDIKPQNVLIFDTTFALCDFSVSAKLHD---------------PNE-LLSGEIGTSFFMAPQVANQEQYKPK------PADMWSLGV . |.| |.....||||||.|.|. |||| |...| | . .|| .||| | .|.. . . .|.|||| GLLYYLHSHHIIHRDIKPANILL----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDTKCDIWSLGC TTYVLIYGTYPY-DLQKIY-------------DTSGQDMVKNNISRIQPLGDLTFPDYPILP-----------------------KDLKDILRGLLDKDP | .. | .|. |.. . . . | ... | || ...|| .. |.||| TIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQ-------------FEQL-CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDP DKRMTAAELVN--HPFI .|| || .| . |||| NKRPTASQLLKSEHPFI |
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| Kinase | 90417.m00127.AA | CAMKK | 32-120 | 27 | 4.9e-25 | 76.02 | In-house | 188-326 (396) | Show / Hide |
Range on Protein: 32-120
Range on HMM: 188-326/396
Sequence Identity: 27% (38 aa)
ALQYMH-ENG-------------------YVHRDIKPQNVLIFDTT----FALCDFSVSAKLHDPNELLSG-----------EIGTSFFMAPQVANQ-EQ
.|.|.| ... .|||||||| || . . ..||.|| .. . ...||. || |||| . .|
GLEYLHNYQKACSYIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVSHIFEGQDQTLSNCESCFQRELNKTAGTPAFMAPELCSKENQ
--------------YKPKPADMWSLGVTTYVLIYGTYPY
|. |.||.|.|||| | ...|. |.
KENYNGYKYRFRFIYCGKAADIWALGVTLYCFVFGKCPF
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| Kinase | 90417.m00127.AA | MARK | 81-186 | 26 | 2.4e-23 | 73.32 | In-house | 167-262 (262) | Show / Hide |
Range on Protein: 81-186 Range on HMM: 167-262/262 Sequence Identity: 26% (28 aa) GTSFFMAPQVANQEQYKPKPADMWSLGVTTYVLIYGTYPYDLQKIYDTSGQDMVKNNISRIQPLGDLTFPDYPILPKDLKDILRGLLDKDPDKRMTAAEL || .|||.. ... | ...|.||||| |... |..|.| |.... ... . |. ..|.. ..|....... || .|..|.|. |. GTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFD--------GDTQDYKELYKKILRGKYDIPCH--VSKECRNLIQRLLTVNPEERPTIEEI VNHPFI ..||.. MKHPWM |
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| Kinase | 90417.m00127.AA | CAMKK | 146-186 | 28 | 6.5e-16 | 46.57 | In-house | 345-396 (396) | Show / Hide |
Range on Protein: 146-186 Range on HMM: 345-396/396 Sequence Identity: 28% (15 aa) DLTFPDY-----------PILPKDLKDILRGLLDKDPDKRMTAAELVNHPFI ...||.. | .. ||||.. ..|.|.|.||.|......||.. PIKFPENKEMLNNVSIYCPEISEDLKDLIKRMLEKNPTKRITIPQIKVHPWV |
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| S_TKc | 90417.m00127.AA | S_TKc | 3-186 | 20 | 7.8e-16 | 55.29 | SMART | 17-231 (231) | Show / Hide |
Range on Protein: 3-186
Range on HMM: 17-231/231
Sequence Identity: 20% (52 aa)
LAKYGA----------------------------------FE---------------------ITKQPE------LTIYDAVRFLDQIGSALQYMHENGY
... |. | |.. .. .| ... || .||.|.|..|
KCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGI
VHRDIKPQNVLIFDTTFALCDFSVSAKLHDPNELLSGEIGTSFFMAPQVANQEQYKPKPADMWSLGVTTYVLIYGTYPYDLQKIYDTSGQDMVKNNISRI
.|||.||.|.|. . . .||| ....| . .|| ..||| | .| ....|.||.|.. | ...| |.. ..|. ..|
IHRDLKPENILLDE-HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--------QMQMMFKKIG--
QPLGDLTFPDYPILPKDLKDILRGLLDKDPDKRMTAAELVN-------HPFI
....||..|..|.|||.||.|| |. . ||..
--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
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| Kinase | 90417.m00127.AA | MARK | 28-53 | 61 | 6.5e-10 | 28.77 | In-house | 112-137 (262) | Show / Hide |
Range on Protein: 28-53 Range on HMM: 112-137/262 Sequence Identity: 61% (16 aa) QIGSALQYMHENGYVHRDIKPQNVLI || ||..|.|... |||||||.|.|| QIVSAVNYCHSKNIVHRDIKPENILI |
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