Gene 80906.m00383 (T.vaginalis)

80906.m00383

Species: T.vaginalis
Alias: 80906.m00383, TvagK0263
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
80906.m00383.AA Protein None 786 None Fasta, JSON
80906.m00383.kin_dom Protein Kinase Domain None 250 None Fasta, JSON

Protein domain

Protein domains of 80906.m00383.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 80906.m00383.AA TKL 211-454 26 1.5e-86 293.83 In-house 1-364 (364) Show / Hide 
Range on Protein: 211-454
Range on HMM: 1-364/364
Sequence Identity: 26% (97 aa)

IGSGVSSNVYIGILKKTK--------EKVAIKALKFEQLQGAKL-------------------------NAFQRELSVLASAQHECLLRFVGATDTYP--
|||| .. || |... .         . ||.| .| .. .   .                           . .|. .. . .|. ...|.|.    |  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------FCIVTEWMPGGSLYNDLNNTGNLSPTERSIAMFDIARGMRCLHNRH--------IIHRDLKTLNVLIDANNR--------------AK
            .|||.|..|||||...|.      .  |   . ||||||  ||...        |||||||. |.|.| |..              .|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

IIDFGLSRYANEQF---------------------MSESIGTPHWMAPELLGSS---------------KQYDLKVDVYAYAIVCWEILMCEVPYEGLLP
| ||||||  .. .                      .  .||| |||||.|  .               ..|. |.|||...|| |||| ...||... .
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY

PQII---------ARVLINDLRPPLE------------DDCPPGLRRLITSCWQRDPNMRPSFNEIITMF
...|         . |  . ||||.             .||||....|.. ||. ||. ||||.||.  .
MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 80906.m00383.AA TKL-Unique 207-454 33 2.4e-73 249.96 In-house 1-290 (290) Show / Hide 
Range on Protein: 207-454
Range on HMM: 1-290/290
Sequence Identity: 33% (98 aa)

IEKEIGSGVSSNVYIGILKKTKEKVAIKALKF-EQLQGAKLNAFQRELSVLASAQ-HECLLRFVGATD----TYP-FCIVTEWMPGGSLYNDLN------
. . ||.|....|| |. ...  .|||| ... | .   ..  | .|....   . |. .....|..     . | .|||.| .||||||. |.      
FWNKIGEGGYGQVYKGKWRGY--PVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

----NTGNLSPTERSIAMFDIARGMRCLHNRH--IIHRDLKTLNVLIDAN-----NRAKIIDFGLSRYANEQ---FMSES--------IGTPHWMAPELL
    |  .|..  |     |||.||  ||..   |||||||..|.|.| |     ...||.|||||. ..     . .|.        .|.. |||||.|
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

GSS-KQYDLKVDVYAYAIVCWEILMCEV------PYEGLLPPQIIARVLI--NDLRPPLEDDCPPGLRRLITSCWQRDPNMRPSFNEIITMF
 .. .||. |.|||...|| |||.  ..      ||.|. . |... |      .|||. ..||. .| ||. || .||  ||||.|||.  
RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 80906.m00383.AA Dicty4 205-456 36 3.3e-67 223.25 In-house 1-277 (277) Show / Hide 
Range on Protein: 205-456
Range on HMM: 1-277/277
Sequence Identity: 36% (103 aa)

LEIEKEIGSGVSSNVYIGILKKTKEKVAIKAL--KFEQLQGAKLNAFQRELSVLASAQHECLLRFVGATDT----YP--FCIVTEWMPGGSLYNDLNN--
. ||..||.|  . || |. . .  .||.| |  . . .  . ||.| .| . ... .|  .. | ||  |     |  .||||| || |.||. |..  
INIEQRIGKGSFGEVYKGTWRGK--EVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGAC-TAPRSHPGKMCIVTEYMPKGNLYSLLHDKP

----TGNLSPTERSIA----MFDIARGMRCLHNRH--IIHRDLKTLNVLIDANNRAKIIDFGLSR----YANEQF-MSESIGTPHWMAPELLGSSKQYDL
        .. .. ..    .||.||||  ||..   |||||||. | |.|.|.|.|. |||||.      . .. ..  .||| ||||| .  .. |. 
SEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVM-MHQPYNE

KVDVYAYAIVCWEILMCEVPYE--GLLPPQIIARVLINDLRPPLEDDCPPGLRRLITSCWQRDPNMRPSFNEIITM--FAK
|.||| ..|| |||| .. ||   .  ..|... |    ||||. |.||| ...||. ||  ||. ||||.|||       
KADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase 80906.m00383.AA MLK 205-454 31 2.7e-65 223.26 In-house 1-291 (291) Show / Hide 
Range on Protein: 205-454
Range on HMM: 1-291/291
Sequence Identity: 31% (91 aa)

LEIEKEIGSGVSSNVYIGILKKTK---EKVAIKALKFEQ----LQGAKLNAFQRELSVLASAQHEC----LLRFVGA-TDT-YPFCIVTEWMPGGSLYND
..... |||| .  |. |  ...      ||.|. ...       ..   .|..|   |.  .|.       .|.|. ... ..||||.|...|||||| 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LNN-TG-------------NLSPTERSIAMFDIARGMRCLHNRH---IIHRDLKTLNVLIDA------NNRAKIIDFGLSRYANEQ-F-MSESIGTPHWM
|.. ..             . ..      ....||||  ||.     |||||||  |.|||.      .  .|| |||.||  ..    |   .||. ||
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWM

APELL--GSSKQYDLKVDVYAYAIVCWEILMCEVPYE-GLLPPQIIARVLINDLRPPLEDDCPPGLRRLITSCWQRDPNMRPSFNEIITMF
||| .    . .|. |.||. ...| ||.| .||||. .. | .|.. |  | ||||.. .||... .|.. ||. ||. |||| .|.. .
APEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
S_TKc 80906.m00383.AA S_TKc 205-461 26 3.7e-65 223.7 SMART 1-231 (231) Show / Hide 
Range on Protein: 205-461
Range on HMM: 1-231/231
Sequence Identity: 26% (71 aa)

LEIEKEIGSGVSSNVYIGILKKTKEKVAIKALKFEQLQGAKLNAFQRELSVLASAQHECLLRFVGATDTYPFCIVTEWMPG--GSLYNDLNNTGN-----
 || ..||.|  . || .. |||...|||| .|         . ..||...| . .|. . .. .. ..  ...|.| ..|  |.|.  . . |      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LSPTERSIAMFDIARGMRCLHNRHIIHRDLKTLNVLIDANNRAKIIDFGLSRYANEQFMSESIGTPHWMAPELLGSSKQYDL-KVDVYAYAIVCWEILM
 ... .    |  |....  .|...|||||||  |.|.|   . ||.||||.|       .  .|||..||||.|    .|.  |.|...  .. .| | 
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLC

CEVPYEGLLPPQIIARVLINDLRPPLEDDCPPGLRRLITSCWQRDPNMRPSFNEIITMF--AKCDIYV
 . |..    .| . ...            .| .. .|  |.|.||. ||.  |. ..   .||. ..
GYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 80906.m00383.AA LRRK 205-456 24 5.2e-63 215.65 In-house 1-351 (351) Show / Hide 
Range on Protein: 205-456
Range on HMM: 1-351/351
Sequence Identity: 24% (86 aa)

LEIEKEIGSGVSS-NVYIGILKK--------------------------TKEKVAIKALKFE---------QLQG-----------------------AK
|.||..||.|..  .|| .....                            ..|||| ....            .                        .
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

LNAFQRELSVLASAQHECLLRFVGATDTYPFCIVTEWMPGGSLYNDLN---NTG------NLSPTERSIAMFDIARGMRCLHNRH--IIHRDLKTLNVLI
.. |..|.... . .| ...  .| .   |.|.|.| .| |.||  |    ..|      ..|.. .   . .||.||. ||...  |||||||. |.|.
FREFRHEVWIMSHLNHPNIVSLKGFC-IHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILL

---D---------ANNRAKIIDFGLSR---YANEQFMSESIGTPHWMAPELLGSS--KQYDLKVDVYAYAIVCWEILMCE-VPYEGLL-P-----PQIIA
   .         |.  |||.|||.||   .  . . . . |.| ||||| ..    ..|. |||.|..... ||.|  .  |....  .       .| 
WSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIE

RVLINDLRPPLEDD-CPP-----GLRRLITSCWQRDPNMRPSFNEIITMFAK
   |. |||..  . |||      .  ||..||| ||. ||.|..|.     
DKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 80906.m00383.AA Pkinase_Tyr 205-454 30 2.6e-62 211.63 Pfam 1-270 (270) Show / Hide 
Range on Protein: 205-454
Range on HMM: 1-270/270
Sequence Identity: 30% (83 aa)

LEIEKEIGSGVSSNVYIGILK----KTKEKVAIKALKFEQLQGAK--LNAFQRELSVLASA-QHECLLRFVGA-T-DTYP--FCIVTEWMPGGSLYNDLN
... |..|.|   .|| |..|    .|| .||.| || |.       . .| ||.... .  .|. ..|..|. | .  |   .||.| ||.|.|.. | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK-EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

N----TGNLSPTERSIAMFDIARGMRCLHNRHIIHRDLKTLNVLIDANNRAKIIDFGLSRYA----NE-QFMSESIGTPHWMAPELLGSSKQYDLKVDVY
.     ..|.. .     ..||.||  |.....||||| . |.|.. || .|| ||||.|.     .  .  ...     ||||| .  .| .  | ||.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSDVW

AYAIVCWEILM-CEVP-YEGLLPPQIIARVLINDLRPPLEDDCPPGLRRLITSCWQRDPNMRPSFNEIITMF
.. ...|||.  .| | |.|. . ......  .  | |  ..||. . .|...||. ||..||.| ||. ..
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 80906.m00383.AA Pkinase 205-454 27 3.2e-62 217.82 Pfam 1-293 (293) Show / Hide 
Range on Protein: 205-454
Range on HMM: 1-293/293
Sequence Identity: 27% (81 aa)

LEIEKEIGSGVSSNVYIGILKKTKEKVAIKALKFEQLQGAKLNAFQR--ELSVLASAQHECLLRFVGAT-DTYPFCIVTEWMPGG----SLYNDLN--NT
..|.. |||| .. ||... |.| ..||.| .| .     |. .  |  |...... .|.. .|. ..  |    ..|.|...||    .|.  .   . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GNL--SPTERSIAMFDIARGMRCLHNRHIIHRDLKTLNVLIDANNRA----KIIDFGLSR---YANEQFMSESIGTPHWMAPELLGSSKQYDLKVDVYAY
|..  |. |    |  |.||.  .|.. |||||||  |.||| |.      ||.||||..   | | . |.   |||..||||.. ... |. |||....
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

AIVCWEILMCEVPYEGL------LPPQIIARVLINDLRPPLEDDCP-------------------PGLRRLITSCWQRDPNMRPSFNEIITM--F
 ....| |  . |. |        . |.|.|..  .|. . . .|.                   . .. .|..|...||. ||.. .|     |
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 80906.m00383.AA TK 205-454 16 5.9e-60 199.34 In-house 1-486 (486) Show / Hide 
Range on Protein: 205-454
Range on HMM: 1-486/486
Sequence Identity: 16% (81 aa)

LEIEKEIGSGVSS---NVYIGILK-------------------------KTKEKVAIKALKFE--QLQGAKLN-------------AFQRELSVLAS--A
....|..|.|       || |...                         ..|..||.| || .  . | ...              .. .|.... .   
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

QHECLLRFVG-ATDT------------YPFCIVTEWMPGGS----LYNDLNNTGN---------------------------------------------
.|. ..|..|  |.              |..||.|.||.|.    | . | .  .                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LSPTERSIAMFDIARGMRCLHNR------HIIHRDLKTLNVLIDANNR-----------AKIIDFG---
                               |.. ..   ...||.||. || .      ...|||| . |.|.. ||.           .|| |||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LSRYAN---EQFMSESIGTPH-------------------------WMAPELLGSSK--------QYDLKVDVYAYAIVCWEILM-CEVPYEGLL
     |.|. .   .   ..| ||.                          ||||| | . .         .  | ||... ...|||.. ...|| | .
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

PP---------QIIARVLIND--------------LRPPLEDDCP--------------PGLRRLITSCWQRDPNMRPSFNEIITMF
.          | . . | .               .|.|  ..||              . . .|...||..||. ||.| ..  ..
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 80906.m00383.AA TyrKc 205-454 28 3.3e-58 200.59 SMART 1-280 (280) Show / Hide 
Range on Protein: 205-454
Range on HMM: 1-280/280
Sequence Identity: 28% (81 aa)

LEIEKEIGSGVSSNVYIGILKKTKEKVAIKALKFEQLQGAKLNAFQRELSVLASA--QHECLLRFVGATDT--------YPFCIVTEWMPGGSLYNDLNN
.. .|..|.|    || |..|   ..||.| || .      . .| ||.... .   .|....|..|.  .         | .||.| ||.|.| . | .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

TGN-LSPTERSIAMFDIARGMRCLHNRHIIHRDLKTLNVLIDANNRAKIIDFGLSRYANEQ----------FMSESIGTP-----HWMAPELLGSSKQYD
... |.. .    ...||.||. || ...||||| . |.|...|...|| ||||||.  .            ..|. |.       ||||| .   . . 
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFT

LKVDVYAYAIVCWEIL-MCEVPYEGL----LPPQIIARVLINDLRPPLEDD--------CPPGLRRLITSCWQRDPNMRPSFNEIITMF
 | ||... ...|||.  .. ||.|     ...| . . . .  |.|  ..        ||. . .....||..||..||.|.||.  |
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 80906.m00383.AA Dicty5 205-458 38 2.6e-56 192.34 In-house 1-260 (260) Show / Hide 
Range on Protein: 205-458
Range on HMM: 1-260/260
Sequence Identity: 38% (103 aa)

LEIEKEIGSGVSSNVYIGILKKTKEKVAIKALKFEQLQGAKLNAFQRELSVLASAQ--HECLLRFVGAT---DTYPFCIVTEWMPGGSLYNDLNNTGN--
  . . | || |  || || |     |||| .  |   .  .| |.||  ..   |  |  . |. ||    | ||| .|||    ||| | ||   .  
VSFHDWIASGASGRVYNGIYK--GMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPF-HVTEYCHNGSLFNYLNDQRKTT

----LSPTERSIAMFDIARGMRCLHNRHIIHRDLKTLNVLIDANNRAKIIDFGLSR-YANEQFMSESIGTPHWMAPELLGSSKQYDLKVDVYAYAIVCWE
    . ..  ..|. |||..|| ||   ||||||| .|.||  |  .|||||| ||  .|   |   .||. |||.||   .. |. |.|||...|| ||
GQPIAYFQQLHMAI-DIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELF-NGQPYHQKCDVYSFGIVLWE

ILMCEVPYEGLLPPQIIARVLINDLRPPLEDDCPPGLRRLITSCWQRDPNMRPSFNEIITMFAKCD
..    ||. .    |   |   . || .  |||     || .|||  |  |||| ||. .| .  
MFTRKEPYDNINNWNIPVMVMKGE-RPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase 80906.m00383.AA Dicty4-Unclassified 205-454 33 6.4e-55 186.52 In-house 1-263 (263) Show / Hide 
Range on Protein: 205-454
Range on HMM: 1-263/263
Sequence Identity: 33% (90 aa)

LEIEKEIGSGVSSNVYIGILKKTKEKVAIKALKFEQLQGAK---LNAFQRELSVLASAQHECLLRFVGATDTYP------FCIVTEWMPGGSLYNDLN--
. | ..|| |  | |. |.  | |. ||.| .  |    .    .  | .|  .| | ||  |..  |.    |      .|||.| |. | |    .  
IQIDQFIGKGHFSKVHKGNW-KGKD-VAVKKFN-ENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYC-INPRSHKSTMCIVMEFMHKGNLFEVIHSK

---NTGNLSPTE---RSIAMFDIARGMRCLHNRHIIHRDLKTLNVLIDANNRAKIIDFGLSRYANEQFMSESIG-TPHWMAPELLGSSKQYDLKVDVYAY
       ..  .     .| ||||.||  || | .||||.|  |.|.| .. .|| |||.||     |    |. || | .|| |     |  | ||| |
PSEQQQPIKLDDTLIIKYA-FDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECL-MHESYNQKSDVYSY

AIVCWEILMCEVPYEGLL-PPQIIARVLINDLRPPLEDDCPPGLRRLITSCWQRDPNMRPSFNEIITMF
|.. .| .  . || .   .  .   |    ||| . | |.. ...||  ||  ||| ||..|.||   
AMMLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase 80906.m00383.AA STE 205-455 20 1.3e-51 177.78 In-house 1-359 (359) Show / Hide 
Range on Protein: 205-455
Range on HMM: 1-359/359
Sequence Identity: 20% (74 aa)

LEIEKEIGSGVSSNVYIGILK------KTKEK---------VAIKALKFEQLQ---------------GAKLNAFQRELSVLASAQ--HECLLRFVGATD
.|. ..||.| .  || .. .      ||.|.         .||| ...|. .                 ... ...|....   .  |.   .. |.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TYP--------FCIVTEWMPGGSLYNDLNNTGNLSPT------------ERSI--AMFDIARG-MRCLHNRHIIHRDLKTLNVLIDANNRAKIIDFGLSR
            .|. |.|.||||   .....    .            |  |    ..| .| .  ||. ||||||.|  |.|.     .|..|||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

YANE------------------QFMSESIGTPHWMAPELLGS-----SKQYDLKVDVYAYAIVCWEILMCEVPYEGLLPPQIIARVLIN-----------
  ..                  |     .||| ||||| .       .|.|| |.|..   ....| .  ..|.  . |.. . . ..|           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---DLRPPLED-------------------DCPPGLRRLITSCWQRDPNMRPSFNEIIT---MFA
   .  |||.|                    . | ..  |  | |.||| ||. .. .     | 
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 80906.m00383.AA TKL-ciliate1 205-454 29 7e-51 172.39 In-house 1-279 (279) Show / Hide 
Range on Protein: 205-454
Range on HMM: 1-279/279
Sequence Identity: 29% (83 aa)

LEIEKEIGSGVSSNVYIGILKKTKEKVAIKALKFEQLQG--AKLNAFQREL-SVLASAQHECLLRFVGATDTY--PFCIVTEWMPGGSLYNDLNNTGN--
  . ..|||| ..||| |  .     |||. ..  ..|     . .||||.       ||. |.  .| .  |   | |..|  ..|..   .  .    
ITMGQKIGSGHFCNVYKGRCNSY--DVAIMNMNYFNSQESFINQKEFQREIQQHIKIKQHINLQQLQG-ISFYDNNFYIIMEHCHKGTMFDICHRKHSQI

--LSPTERSIAMFDIARGMRCLHNRH--IIHRDLKTLNVLIDANNRAKIIDF--------GLSRYANEQFM---SESIGTPHWMAPELLG----SSKQYD
  ..   |     |||.||  || |   .|||||| .| | |  .. || .|        .. |  . | |   ..  .|.|||||| .     . ... 
YMIKWQHRMRWCKDIAQGMQYLHMRQNPLIHRDLKMQNILYDEPYQYKICNFPHVKIADFHRIRNCSFQDMQNEMQRNTTFHWMAPEQMDPHIFPNYPIN

LKVDVYAYAIVCWEILMCEVPY-EGLLPPQIIARVLINDLRPPL-----EDDCPPGLRRLITSCWQRDPNMRPSFNEIITMF
 |.|.|||.|| ..    . |. . .    |.  .     || |       |||. .  |.  || ..|| ||.|||||   
EKIDIYAYGIVMYILCFRKTPFQQKMSVINIMCYWCEFPGRPNLGPQFIHFDCPQNFHNLMMRCWCQNPNKRPNFNEIIQIL