Gene 96800.m00254 (T.vaginalis)

96800.m00254

Species: T.vaginalis
Alias: TvagK0350, 96800.m00254
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
96800.m00254.AA Protein None 938 None Fasta, JSON
96800.m00254.kin_dom Protein Kinase Domain None 259 None Fasta, JSON

Protein domain

Protein domains of 96800.m00254.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 96800.m00254.AA MLK 35-288 36 2.7e-97 329.56 In-house 1-291 (291) Show / Hide 
Range on Protein: 35-288
Range on HMM: 1-291/291
Sequence Identity: 36% (108 aa)

LELQKRIGSGGFAEVFYG-YRKSD--GTVVAIKRLRNQQFDAKML-----EMFKREVGILAGLRHFA----ILPFVGACTKP-P-FCIVTEFMSGGSLFS
..... ||||.| .|. | .|. |    .||.|| |   | .|       . |..|. .|. |.|      | .|.|.|..| . ||||.|...||||..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

RLHTKEITNR-----------LSPTQLSIIALGVAYGMAFLHDNQ---MLHRDLKSLNILLDA------ENFPKICDFGMARAKSNSSEPMTGEIGTSQW
 ||....               .. ..  .|| .| ||..|| ..     |||||| |||.|.      .   |||||| .| .... . |.. .||  |
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAW

MAPEVL---ISQKYDEKADVYSYGIILWEMLTGDVPYR-GLRDIQIAMSVVNQNNRPKIPKNCPHNLEKFIRICWDSDPSKRPDFNTIVRAL
|||||.    ..||.||.||.|.|..||||||. |||. ..  ..||. |.. ..|| ||..||. ..|.. .||..||.|||.|  ||  |
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 96800.m00254.AA TKL 41-288 29 2.5e-91 309.73 In-house 1-364 (364) Show / Hide 
Range on Protein: 41-288
Range on HMM: 1-364/364
Sequence Identity: 29% (111 aa)

IGSGGFAEVFYG-YRKSD-------GTVVAIKRLRNQQFDAKML-----------------------EMFKREVGILAGLR--HFAILPFVGACTKPP--
||||||.||. | .|  .       |..||.|... .. | ...                       ..|..|. |.  .|  |  |..|.|.|. ||  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------FCIVTEFMSGGSLFSRLHTKEITNRLSPTQLSIIALGVAYGMAFLHDNQ--------MLHRDLKSLNILLD--------------AEN
            .|||.|...||||...||         . |.  .||..| ||..|| ..        ..|||||| |||.|              |. 
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

FPKICDFGMARAKSNS-SEPMTG------------------EIGTSQWMAPEVLISQ----------------KYDEKADVYSYGIILWEMLTGDVPYRG
..|||||| .| .|.| .  .|.                  ..|| .|||||||  |                .|.||.||||.||.|||.||. .||..
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYD

LRDIQIA---------MSVVNQNNRPKIP------------KNCPHNLEKFIRICWDSDPSKRPDFNTIVRAL
.  ...          | |.. ..|| ||            ..||. . | .  |||.||.||| |..|.  |
YPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 96800.m00254.AA Dicty4 35-290 40 6.3e-91 303.47 In-house 1-277 (277) Show / Hide 
Range on Protein: 35-290
Range on HMM: 1-277/277
Sequence Identity: 40% (114 aa)

LELQKRIGSGGFAEVFYGYRKSDGTVVAIKRL--RNQQFDAKMLEMFKREVGILAGLRHFAILPFVGACT----KP-PFCIVTEFMSGGSLFSRLHT---
.  ..|||.|.|.||. |  .  |. ||.| |  .|| ||..||. |..|| |.. .||  |. | ||||    .|  .|||||.|. |.|.| ||    
INIEQRIGKGSFGEVYKGTWR--GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPS

---KEITNRLS-PTQLS--IIALGVAYGMAFLHD-N-QMLHRDLKSLNILLDAENFPKICDFGMAR----AKSNSSEPMTGEIGTSQWMAPEVLISQKYD
   ..|.  |. |. ..   .|. .| ||. ||  |   .|||||| |.| |. .  |.|||| ..     ....   ... .||  ||||||. .| |.
EQQQSIK--LDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDN-QMTACGTPCWMAPEVMMHQPYN

EKADVYSYGIILWEMLTGDVPYR--GLRDIQIAMSVVNQNNRPKIPKNCPHNLEKFIRICWDSDPSKRPDFNTIVRA--LES
|||||||.||.|||.||.. ||   .    |.. .|.|  .||.||..|| .. . |  ||| ||..|| |. |. .  ||.
EKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase 96800.m00254.AA TKL-Unique 37-288 34 1.4e-84 287.3 In-house 1-290 (290) Show / Hide 
Range on Protein: 37-288
Range on HMM: 1-290/290
Sequence Identity: 34% (102 aa)

LQKRIGSGGFAEVFYGYRKSDGTVVAIKRLR-NQQFDAKMLEMFKREVGILAGLR-HFAILPFVGACT----KPP-FCIVTEFMSGGSLFSRLHT-----
  . ||.||...|. |  .  |. ||||..  |  .  .|.. |..|| ..  |. |  |. ..|.|.    .|| .|||.|...|||| . ||.     
FWNKIGEGGYGQVYKGKWR--GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

---KEITNRLSPTQLSIIALGVAYGMAFLHDNQ--MLHRDLKSLNILLDAE-----NFPKICDFGMARAKSNSSEPMTGEI---------GTSQWMAPEV
   .. .. |.. |   .|. .| || .|| ..  ..||||||.|.|.| .     .  |||||| .. .|....  ..|.         |. .||||||
NNNNNNCK-LNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEV

LIS--QKYDEKADVYSYGIILWEMLTGDV------PYRGLRDIQIAMSVVN--QNNRPKIPKNCPHNLEKFIRICWDSDPSKRPDFNTIVRAL
| .   .|.||.||||.||.|||..|...      ||.|. ..|..  |     | ||.|| .|| .. . |. ||..|||.|| |..|.  |
LRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 96800.m00254.AA HH498 35-288 34 3.3e-79 250.69 In-house 1-284 (284) Show / Hide 
Range on Protein: 35-288
Range on HMM: 1-284/284
Sequence Identity: 34% (100 aa)

LELQKRIGSGGFAEVFYGYRKSDGTVVAIKRLRNQQFDAKML------EMFKREVGILAGLRHFAILPFVGACTKPP--FCIVTEFMSGGSLFSRL----
.| .. |||| | .|. |.    . .||.|| | . | .|         || ||| |.  | |.    ||.||   |  | |||.. ..|||||.|    
IEFHEKIGSGSFGKVYKGEWR--NKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYACCDDPSQFAIVTQYCDNGSLFSILNTIP

----------HTKEITNR-LSPTQLSIIALGVAYGMAFLHD---NQMLHRDLKSLNILLDAENFPKICDFGMAR-AKSNSSEPMTGEIGTSQWMAPEVLI
          |      | ...    .|.. || || .||.    .  |||| | |||....   .. |||  |  ..   . ||  .|   ||||||  
IGGAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFS

-SQKYDEKADVYSYGIILWEMLTGDVPYRGLRDIQIAMSVVNQNNRPKIPKN----CPHNLEKFIRICWDSDPSKRPDFNTIVRAL
 .|||..|.||.||....|||.|. ||.  .  .  |  . ..  || ||       ||     | .||.  |. ||||  ||. |
QCQKYSIKVDVFSYAMCIWEMHTREVPFHHYKPAAAAAEMAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL
Kinase 96800.m00254.AA Dicty4-Unclassified 35-288 37 2.9e-76 259.67 In-house 1-263 (263) Show / Hide 
Range on Protein: 35-288
Range on HMM: 1-263/263
Sequence Identity: 37% (100 aa)

LELQKRIGSGGFAEVFYGYRKSDGTVVAIKRLRNQQFDAK--MLEMFKREVGILAGLRHFAILPFVGACTKP-----PFCIVTEFMSGGSLFSRLH----
.   . || | |..|  |  |  |  ||.| .   .| .   |.. ||.|| ||  . |   .   |.|  |      .|||.|||  | ||   |    
IQIDQFIGKGHFSKVHKGNWK--GKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPS

TKEITNRLSPTQLSIIALGVAYGMAFLHDNQMLHRDLKSLNILLDAENFPKICDFGMARAKSNSSEPMTGEIGTSQWMAPEVLISQKYDEKADVYSYGII
 ..   .|  |    .|. .| ||..||   . |||.|| |||.|  .  || |||..|  ..    ||   ||  | .||.|    |  |.|||||...
EQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFN-MTTIAGTPKWESPECLMHESYNQKSDVYSYAMM

LWEMLTGDVPYRGLR-DIQIAMSVVNQNNRPKIPKNCPHNLEKFIRICWDSDPSKRPDFNTIVRAL
|.|..||| || .    . .| ||     ||||| ||. .. | |  ||  || ||| .| |.  |
LYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase 96800.m00254.AA Pkinase_Tyr 35-288 31 8.2e-74 250.61 Pfam 1-270 (270) Show / Hide 
Range on Protein: 35-288
Range on HMM: 1-270/270
Sequence Identity: 31% (86 aa)

LELQKRIGSGGFAEVFYGYRK----SDGTVVAIKRLRNQQFDAKM--LEMFKREVGILAGL-RHFAILPFVGACT--KPP--FCIVTEFMSGGSLFSRLH
... | .|.| | ||. |. |    .... ||.| | ... . .   .|.| ||. |.  | .|  |. ..|.||  . |   .||.|.| .|.| . |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

TK-EITNRLSPTQLSIIALGVAYGMAFLHDNQMLHRDLKSLNILLDAENFPKICDFGMARAK--SNSS-EPMTGEIGTSQWMAPEVLISQKYDEKADVYS
.. |  ..|.. .|  ... .| ||..|..... ||||   |.|.. .|. ||||||.||.           .|      |||||..   |. .| ||.|
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

YGIILWEMLT-GDVP-YRGLRDIQIAMSVVNQNNRPKIPKNCPHNLEKFIRICWDSDPSKRPDFNTIVRAL
.|. .||..| |. | | |. . ..   .  ...| ..|.|||  . . .. ||. ||..|| |  |.. |
FGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 96800.m00254.AA DRK 35-290 37 2.8e-73 247.55 In-house 1-258 (258) Show / Hide 
Range on Protein: 35-290
Range on HMM: 1-258/258
Sequence Identity: 37% (99 aa)

LELQKRIGSGGFAEVFYG-YRKSDGTVVAIKRLRNQQFD-AKMLEMFKREVGILAGLRHFAILPFVGACTKPP-FCIVTEFMSGGSLFSRLHTKEITNRL
   . ||| |...||| |  |   || ||.|.| |   .  ..|  |.||. ..  |||  |  | |.|. ||  ||..|.|. ||| . ||   |   .
IKIGNRIGRGNYGEVFRGTWR---GTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESI--EM

SPTQLSIIALGVAYGMAFLHDNQ--MLHRDLKSLNILLDAENFPKICDFGMAR--AKSNSSEPMTGEIGTSQWMAPEVLISQKYDEKADVYSYGIILWEM
.   .  ... .| || .||      .|||||| | | |     |. ||| .    |  .       .||  | ||||| .| | |||||||..|.|||.
DWPLMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWEC

LTGDVPYRGLRDIQIAMSVVNQNNRPKIPKNCPHNLEKFIRICWDSDPSKRPDFNTIVRALES
.|   || |    |. .||     || .|..||    . .  ||. ||. || .  ..  ||.
VTRQDPYFGMPTFQVVFSVGRHGMRPPMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase 96800.m00254.AA TyrKc 35-288 29 1e-70 242.13 SMART 1-280 (280) Show / Hide 
Range on Protein: 35-288
Range on HMM: 1-280/280
Sequence Identity: 29% (86 aa)

LELQKRIGSGGFAEVFYGYRKSDGTVVAIKRLRNQQFDAKMLEMFKREVGILAGL--RHFAILPFVGACTK--------PPFCIVTEFMSGGSLFSRLHT
..| | .|.| | ||. |  |   . ||.| |..       .|.| ||  |.  |  .|  |. ..|.||.        .| .||.|.|..|.| ..|. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KEITNRLSPTQLSIIALGVAYGMAFLHDNQMLHRDLKSLNILLDAENFPKICDFGMARAKSNS-------SEPMT----GEI--GTSQWMAPEVLISQKY
.. .  |.. .|  ... .| ||..||...  ||||   |.|.....  ||.|||..|.  .        .  ..    |.       |||||..   |.
HRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

DEKADVYSYGIILWEMLT-GDVPYRGL----RDIQIAMSVVNQNNRPKIPKN--------CPHNLEKFIRICWDSDPSKRPDFNTIVRAL
 .| ||.|.|. .||..| |. || |      . | ..  | | .|...|.|        ||  . . .. ||. ||..|| |..|.. .
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 96800.m00254.AA Pkinase 35-288 26 1.7e-68 238.63 Pfam 1-293 (293) Show / Hide 
Range on Protein: 35-288
Range on HMM: 1-293/293
Sequence Identity: 26% (79 aa)

LELQKRIGSGGFAEVFYGYRKSDGTVVAIKRLRNQQFDAKMLEMFKR--EVGILAGLRHFAILPFVGAC-TKPPFCIVTEFMSGG----SLFSRLHTKEI
... ..||||.|..|. ...|..| .||.|... .  . ....   |  |. |.. |.|  |. . ... .|.  ..|.|.. ||    .||....| . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST-WR

TNRL--SPTQLSIIALGVAYGMAFLHDNQMLHRDLKSLNILLDAENFP----KICDFGMARAK-SNSSEPMTGEIGTSQWMAPEVLI-SQKYDEKADVYS
 ...  |. ..  ... .. |....|..  .|||||. |||.| .. .    |||||| |. .   ... ||.  ||. .|||||.  .|.|. |.|..|
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

YGIILWEMLTGDVPYRGL---RDIQIAMSVVNQNNRPKIPKNCP-----------------------HNLEKFIRICWDSDPSKRPDFNTIVRA--L
.|.||.|||.|  |..|     .    | ..... .|... ..|                        .. .||. |.. ||.||| .  |.    .
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 96800.m00254.AA TK 35-288 16 4.1e-65 216.96 In-house 1-486 (486) Show / Hide 
Range on Protein: 35-288
Range on HMM: 1-486/486
Sequence Identity: 16% (82 aa)

LELQKRIGSGGFA---EVFYGYRKSDG-------------------------TVVAIKRLR---NQQFDAKMLEMFK---------REVGILAGLR----
..| | .|.| |    ||. |  ....                         | ||.| |.   ... .....|...         .|. ... ..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HFAILPFVGACTK-------------PPFCIVTEFMSGGS----LFSRLHTKEITNR------------------------------------------
 |  |. ..|.||.             .|..||.|.|..|.    | . |...  . .                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LSPTQLSIIALGVAYGMAFLHDN------QMLHRDLKSLNILLDAENF-----------PKICDFGMA-
                               |.. ||  ... .| ||..||..      .. ||||   |.|.. .|             ||.|||.. 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----RAKSNSSEPMTGEIGTSQ----------------------------WMAPEVLISQK---------YDEKADVYSYGIILWEMLT-GDVPYRGLR
     .|.   |.      ..                              |||||.| ...         . .| ||.|.|. .||..| |..|| |  
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

DI---------QIAMSVVNQN--------------NRPKIPKNCP--------------HNLEKFIRICWDSDPSKRPDFNTIVRAL
.          |  |  . .               .|.. |..||                .. ... ||. ||..||.| .....|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 96800.m00254.AA LRRK 35-290 26 2.6e-64 219.95 In-house 1-351 (351) Show / Hide 
Range on Protein: 35-290
Range on HMM: 1-351/351
Sequence Identity: 26% (95 aa)

LELQKRIGSGGFA-EVFYGYRKSD--------------------------GTVVAIKRLRN--------------------------------QQFDAKM
|. .. ||.|||. .|. .  ..                           .. |||| .                                   .. .. 
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

LEMFKREVGILAGLRHFAILPFVGACTKPPFCIVTEFMSGGSLFSRLHTKEITN------RLSPTQLSIIALGVAYGMAFLHDNQ--MLHRDLKSLNILL
.  | .|| |. .|.|  |.. .| | . |.|.|.|... |.| ..|| |. .       ..|.. .  ||| .| ||..||..    .|||||| ||||
FREFRHEVWIMSHLNHPNIVSLKGFCIH-PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILL

---D---------AENFPKICDFGMAR-AKSNSSEPMTGEIGTSQWMAPEVLISQ---KYDEKADVYSYGIILWEMLTGD-VPYRGLR--D----IQIAM
   .         |.   ||.|||  |  ..  ..   |  |. .|||||..       |.||.|.||.|.|||| ||..  |....   |    . .  
WSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIE

SVVNQNNRPKIPKN-CPH-----NLEKFIRICWDSDPSKRPDFNTIVRALES
  ..   ||.|| . ||.      ... |  ||. || ||| |..||  |..
DKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 96800.m00254.AA CZAK 35-288 36 3.3e-62 213.0 In-house 1-279 (279) Show / Hide 
Range on Protein: 35-288
Range on HMM: 1-279/279
Sequence Identity: 36% (102 aa)

LELQKRIGSGGFAEVFYGYRKSDGTVVAIKRLRNQQFDAKML----EMFKREVGILAGLRHFAILPFVGACTKPP---FCIVTEFMSGGSLFSRLHTKEI
|.  . || | | ||  .| .  |..|||| .   ||  |      .|| .||.|.  |.|  .. |.|||.       |||.|.| ||||  || |   
LKFGQTIGQGFFGEVYKAYWR--GKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSL-RRLLTDHY

TNRLS-PTQLSIIALGVAYGMAFLHD----NQMLHRDLKSLNILLDAENFP--------------KICDFGMARAKSNSSEPMTGEIGTSQWMAPEVLIS
   .  |     .|. .| || .|||    |  ||||| | ||||| ..                || |||  | .      ||  .|   |||||. . 
FYHKQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLD-HSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPECFKG

QKYDEKADVYSYGIILWEMLTGDVPYRGLRDIQIAMSVVNQNNRPKIPKNCPHNLE---KFIRICWDSDPSKRPDFNTIVRAL
  | ||.||||.|.|||...|.| || ... . .|      | || .|   .   .   . |  ||.. |. || |  |.  |
ENYTEKVDVYSFGMILWCIITCDQPYQNMQPMKMAHLAAYENYRPPMPQPMDPMWKNLGELIEMCWNKNPDERPSFKQILQHL
Kinase 96800.m00254.AA S_TKc 35-293 28 4.3e-61 210.2 SMART 1-231 (231) Show / Hide 
Range on Protein: 35-293
Range on HMM: 1-231/231
Sequence Identity: 28% (76 aa)

LELQKRIGSGGFAEVFYGYRKSDGTVVAIKRLRNQQFDAKMLEMFKREVGILAGLRHFAILPFVGACTKPPFCIVTEFMSG--GSLFSRLHTKEI-TNR-
 |. . ||.|.|..|. .. |..| .||||...         |...||. ||   .|  |  . ...    ...|.|...|  |.||.... .    .| 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LSPTQLSIIALGVAYGMAFLHDNQMLHRDLKSLNILLDAENFPKICDFGMARAKSNSSEPMTGEIGTSQWMAPEVLISQKYDE-KADVYSYGIILWEML
 ... .   ..  .. .....|... .|||||  |||||     ||||||.||         |  .||  .||||||   .|.  |.|..| |.||.|||
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

TGDVPYRGLRDIQIAMSVVNQNNRPKIPKNCPHNLEKFIRICWDSDPSKRPDFNTIVR----ALESGAI
.|  |..   ..|  . ..            .. .  ||| |.. ||.|||    . .    .     .
CGYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF