Gene 85144.m00112 (T.vaginalis)

85144.m00112

Species: T.vaginalis
Alias: 85144.m00112, TvagK0462
External Links:
Annotation:

Classification

Group: CK1
Family: CK1
Subfamily: CK1-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
85144.m00112.AA Protein None 308 None Fasta, JSON
85144.m00112.kin_dom Protein Kinase Domain None 108 None Fasta, JSON

Protein domain

Protein domains of 85144.m00112.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 85144.m00112.AA CK1 2-230 21 1.3e-37 128.78 In-house 40-339 (339) Show / Hide 
Range on Protein: 2-230
Range on HMM: 40-339/339
Sequence Identity: 21% (64 aa)

LKIETESDNKK-STLLNEHRVYEVIQKK---------QPEEYR----KRFLIEYAYDKRSN--VHISALELLGANLDDLKR-VTN-GYLVDINNTLRIAV
.|.| .. ... ..|. |...|.  |..          .  .     . . . | | .. .   ..  ..||| ||.||..  .. .     . .|.||.
MKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEEDDYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAI

ETLRCIKDLHAMGIVHGDIKPGNFLVRP--------------NRRFPIALIDFGLSE---IEDEDNG--------------------SSKYKG-TPKYSS
 .|  ....| .|..| ||||.||..                |..  . .||||..    ... ...                      .. | |..| |
QMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYRDKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCS

LPVLSGTRPKKCDDIYSWIISMVYLLCGS--LPWSHINNKDK-----IKEMMEDEDGEKFKKF------------VPQELMEIYQYASSLANDDRNAEID
. .  |  .   ||..||.  ....| |.  |||.... ..|     . .| ..   || ...            .|||. .|..| .||  .||    |
INCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKMSTPFFLCCPKKDHDCPQEF-KIMKYIRSLKYYDR---PD

YEKI
||.|
YEMI
Kinase 85144.m00112.AA Worm8 90-125 54 5.2e-13 33.91 In-house 113-149 (261) Show / Hide 
Range on Protein: 90-125
Range on HMM: 113-149/261
Sequence Identity: 54% (20 aa)

KDLHAMGIVHGDIKPGNFLV-RPNRRFPIALIDFGLS
.| |..||||||||. | .|   || |   |.|||.|
QDIHSFGIVHGDIKADNLMVSHSNRMFMLVLVDFGCS
Kinase 85144.m00112.AA TTBKL 53-125 28 9.5e-13 39.44 In-house 78-156 (288) Show / Hide 
Range on Protein: 53-125
Range on HMM: 78-156/288
Sequence Identity: 28% (23 aa)

ALELLGANLDDLKRVTNGYL-VDINNTLRIAVETLRCIKDLHAMGIVHGDIKPGNFLVRPN------RRFPIALIDFGLS
...|.| ||.||..  .         ..||.. .| ..|..| .|..| |.||.|. .  .      .|  . |||||..
VMTLCGPNLQDLRKMMPNKKRFSDGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRH-VYLIDFGMA
Kinase 85144.m00112.AA CAMK1 92-143 41 2.4e-12 32.14 In-house 124-179 (276) Show / Hide 
Range on Protein: 92-143
Range on HMM: 124-179/276
Sequence Identity: 41% (23 aa)

LHAMGIVHGDIKPGNFLVRPN-RRFPIA--LIDFGLSEIEDEDN-GSSKYKGTPKY
.|..|||| |.|| | | ...   ..|.  ..||||| |.|.|.   ..  ||| |
MHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGY
Kinase 85144.m00112.AA TTBKL 157-234 29 4.7e-12 37.06 In-house 209-288 (288) Show / Hide 
Range on Protein: 157-234
Range on HMM: 209-288/288
Sequence Identity: 29% (25 aa)

CDDIYSWIISMVYLLCGSLPWSHINNKDKIKEMMEDEDGEKFKKF------VPQELMEIYQYASSLANDDRNAEIDYEKIEDLL
.||..||. ....|.|| |||.....|..| .|...  .|.. |        |.|. ..... .|| . ||    |||.|  ..
HDDLWSWMYMIIELHCG-LPWTNMEDKMEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRP---DYEMIYECF
Kinase 85144.m00112.AA CAMK 92-145 22 1.1e-11 33.2 In-house 195-287 (425) Show / Hide 
Range on Protein: 92-145
Range on HMM: 195-287/425
Sequence Identity: 22% (21 aa)

LHAMGIVHGDIKPGNFLVRPNRR---------------FPIALIDFGLS--EIEDEDNG----------------------SSKYKGTPKYSS
.| ..||| |.|| | |.  | .               ..| .||||..   ...|.|                        . . ||| | .
CHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMA
Kinase 85144.m00112.AA CDC7 86-136 36 1.9e-11 29.0 In-house 118-167 (522) Show / Hide 
Range on Protein: 86-136
Range on HMM: 118-167/522
Sequence Identity: 36% (19 aa)

LRCIKDLHAMGIVHGDIKPGNFL-VRPNRRFPIALIDFGLSEIEDEDNGSSK
..  . .| .||.| |.||.|||  | ...|  .|.||||... .  |  |.
FYALRHVHQFGIIHRDVKPSNFLYNRRTKKF--LLVDFGLAQHMMDYNECSR
Kinase 85144.m00112.AA Ciliate-E2 81-158 24 4.9e-11 34.11 In-house 165-278 (365) Show / Hide 
Range on Protein: 81-158
Range on HMM: 165-278/365
Sequence Identity: 24% (30 aa)

IAVETLRCIKDLHAMG-IVHGDIKPGNFLVRPNRRFPIALIDFGLSEIEDEDNGSSKY----K----------------------------GTPKYSSLP
.... . ... ||  . |.| |||| | |.       | .|||||| . |.||    .    |                            ||| | .  
YIACIILALEYLHSKNNIIHRDIKPENILF-------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPE

VLSGT----------RPKKCD
.|.|             .|||
ILNGKKYDNQQKQKGYDYKCD
Kinase 85144.m00112.AA S_TKc 9-250 12 1e-09 -34.27 SMART 1-231 (231) Show / Hide 
Range on Protein: 9-250
Range on HMM: 1-231/231
Sequence Identity: 12% (37 aa)

DNKKSTL---------LNEHRV--YEVIQKKQPEEYRKRFLIE---------------YAYDKRSNVHISALELLGA---NLDDLKRVTNG----YLVDI
  .  ..         .  |.    .|  |. .    .... |               ....   .     .|...    .| |. .  ..    .  . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKKHHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE

NNTLRIAVETLRCIKDLHAMGIVHGDIKPGNFLVRPNRRFPIALIDFGLSEIEDEDNGSSKYKGTPKYSSLPVLSGTRPKK-CDDIYSWIISMVYLLCGS
  . ... .... .. .| .||.| |.|| | |.       | ..||||. .       . . ||| | .  ||      |   |..|  . .  .||| 
-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGY

LPWSHINNKDKIKEMMEDEDGEKFKKFVPQELMEIYQYASSLANDDRNAEIDYEKIEDLLARSIVRHYV------QWK-------DPYF
 |..   . ... ...                                     .   |.. .  ..           .       .|.|
PPFP---QMQMMFKKIG-----------------------------------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase 85144.m00112.AA nmo 86-132 44 2.4e-09 24.26 In-house 112-156 (292) Show / Hide 
Range on Protein: 86-132
Range on HMM: 112-156/292
Sequence Identity: 44% (21 aa)

LRCIKDLHAMGIVHGDIKPGNFLVRPNRRFPIALIDFGLSEIEDEDN
|| .| ||. .|.| |||||| ||  |    . . ||||  ....|.
LRGLKYLHSANILHRDIKPGNLLV--NSNCVLKICDFGLARVWEQDQ
Kinase 85144.m00112.AA BUB 78-110 36 2.5e-09 29.26 In-house 124-156 (311) Show / Hide 
Range on Protein: 78-110
Range on HMM: 124-156/311
Sequence Identity: 36% (12 aa)

TLRIAVETLRCIKDLHAMGIVHGDIKPGNFLVR
.. .... |. ...||...|.|||||| ||. .
VMFFCCQMLKMVEHLHRCEIIHGDIKPDNFMLM
Kinase 85144.m00112.AA TTBK 54-124 36 6.1e-09 27.77 In-house 75-147 (257) Show / Hide 
Range on Protein: 54-124
Range on HMM: 75-147/257
Sequence Identity: 36% (27 aa)

LELLGANLDDLKRVTNGYLVDINNTLRIAVETLRCIKDLHAMGIVHGDIKPGNFLV--RPNRRFPIALIDFGL
..|.| || || |        .  |||. |  |  |.  | .|  | |||| || .   | ..  . ..||||
MQLQGKNLADLRRKQPRGCFSLSTTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGL
Kinase 85144.m00112.AA Pkinase 92-187 27 2e-06 23.67 Pfam 124-225 (293) Show / Hide 
Range on Protein: 92-187
Range on HMM: 124-225/293
Sequence Identity: 27% (29 aa)

LHAMGIVHGDIKPGNFLVRPNRRFP---IALIDFGLSEI--EDEDNGSSKYKGTPKYSSLPVLS-GTRPKKCDDIYSWIISMVYLLCGSLPWSHI----N
.|.|||.| |.|| |.|.  |.  .   . ..||||..   .  .   . . ||| | .  |.  |.   .  |..|  . . ..||| .|...     |
CHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN

NKDKIK
  |...
-HDQMQ
Kinase 85144.m00112.AA APH 96-125 28 0.000748 14.02 Pfam 171-202 (248) Show / Hide 
Range on Protein: 96-125
Range on HMM: 171-202/248
Sequence Identity: 28% (9 aa)

GIVHGDIKPGNFLVR--PNRRFPIALIDFGLS
...||| .|||....  |.    ...||.. .
CWCHGDFHPGNVMWDPRPDGGRVTGVIDWDDA
Kinase 85144.m00112.AA TTBK 158-230 34 0.009139 5.64 In-house 188-257 (257) Show / Hide 
Range on Protein: 158-230
Range on HMM: 188-257/257
Sequence Identity: 34% (25 aa)

DDIYSWIISMVYLLCGSLPWSHINNKDKIKEMMEDEDGEKFKKFVPQELMEIYQYASSLANDDRNAEIDYEKI
||  |    .|  . | |||  |  ||.. || |  |     | .|.|.    .  .||   ||    ||  |
DDLWSLFYMLVEFVQGQLPWRKIKDKDQVGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRP---DYQLI