Gene 93567.m00048 (T.vaginalis)

93567.m00048

Species: T.vaginalis
Alias: 93567.m00048, TvagK0330
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
93567.m00048.AA Protein None 818 None Fasta, JSON
93567.m00048.kin_dom Protein Kinase Domain None 249 None Fasta, JSON

Protein domain

Protein domains of 93567.m00048.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 93567.m00048.AA TKL 32-273 26 1.1e-81 277.66 In-house 1-364 (364) Show / Hide 
Range on Protein: 32-273
Range on HMM: 1-364/364
Sequence Identity: 26% (99 aa)

IGSGGFGEVWIGNYIPSN--------TKVAIKKLFADE-----------------------------LSEQTMSEISLHASLSQQFLVPFIGYTNEKP--
|||||||||. |..   .        . ||.||.  ..                             . ..   || .. .|. . .|.|.|| .. |  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------LCIVTQYISNGSLYDALHNQNPQVSLSPTDLTIIAFGIASGMAYIHSRN--------IIHRDLKTLNILLDSQLL-------------
            ||||..|...|||.. ||         .  .  .| .||.||.| ||.|        |||||||. |||.|. .              
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-PKIIDFGTSSSNKSRAINQD---------------------VGTAAIMAPELHR----------------FEKYDQSVDVYSYGIILWEMLTHDIPF--
 .|| |||.| ... .  ..|                     .|| . ||||. |                ...|....||||.||.|||.||  .|.  
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYD

GDKEPVQIV-------YCVAQKGERPILP------------NDVPIPLMKLINSCWAEDPKQRPAFSEICAKF
 . .|...        . |..||.|| .|            .|.| .. ||.  ||..||..|| |.||  ..
YPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 93567.m00048.AA MLK 26-273 32 9.8e-74 251.28 In-house 1-291 (291) Show / Hide 
Range on Protein: 26-273
Range on HMM: 1-291/291
Sequence Identity: 32% (95 aa)

LTFEKVIGSGGFGEVWIGNYIPSNTK-----VAIKKLF--------ADELSEQTMSEISLHASLSQQF----LVPFIGYTNEK-P-LCIVTQYISNGSLY
..|...||||.||.|| |..   |.      ||.|. .        ... ...   |. . . ||..      ..| |  ..  . .|||..|...||||
IQFHEWIGSGSFGKVWKGRWR--NKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLY

DALHNQNPQVS-----------LSPTDLTIIAFGIASGMAYIHSRN---IIHRDLKTLNILLDS------QLLPKIIDFGTSSSNKSR-A-INQDVGTAA
. ||..... .            ..  .  .|. .|.||.| ||     |||||||  |||.|       ..  || ||||| . ... .      ||.|
NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYA

IMAPEL---HRFEKYDQSVDVYSYGIILWEMLTHDIPFG-DKEPVQIVYCVAQKGERPILPNDVPIPLMKLINSCWAEDPKQRPAFSEICAKF
 ||||     | |||. ..||.|.|..||||||  .|.  . .| .| . ||..|.|| .|.. | .. ||.. || .||..|| |..|  ..
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 93567.m00048.AA Dicty4 26-276 33 3e-68 226.77 In-house 1-277 (277) Show / Hide 
Range on Protein: 26-276
Range on HMM: 1-277/277
Sequence Identity: 33% (94 aa)

LTFEKVIGSGGFGEVWIGNYIPSNTKVAIKKL--FADELSEQTMS----EISLHASLSQQFLVPFIGYTN---EKP--LCIVTQYISNGSLYDALHN---
...|. ||.|.||||  |.     ..||.|||    . ..| ...    |... ....   .. | |. .    .|  .|||| | . |.||  ||.   
INIEQRIGKGSFGEVYKGTWR--GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPS

-QNPQVSLSPTDLTI---IAFGIASGMAYIHSRN--IIHRDLKTLNILLDSQLLPKIIDFGTSSSNKSRAINQD-----VGTAAIMAPELHRFEKYDQSV
 | . ..|. .. .    .|| .| ||.. |..|  |||||||. |.| |  .  |. ||| |   |    ..|     .||.. ||||  ... |....
EQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKA

DVYSYGIILWEMLTHDIPFG--DKEPVQIVYCVAQKGERPILPNDVPIPLMKLINSCWAEDPKQRPAFSEICAK-FLSG
||||.||.|||.|| ..|.    ....|.|  |..|..||..|...| .. .||. || .||..|| |.||  .  |  
DVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase 93567.m00048.AA TKL-Unique 28-273 32 3.3e-66 226.25 In-house 1-290 (290) Show / Hide 
Range on Protein: 28-273
Range on HMM: 1-290/290
Sequence Identity: 32% (96 aa)

FEKVIGSGGFGEVWIGNYIPSNTKVAIKKLFADELSEQTMSE-ISLHA---SLSQ--QFLVPFIGYTNE---KPL--CIVTQYISNGSLYDALH------
| ..||.||.|.|  | .    ..||||...  |.|. .|..  . .    .  .   ..| ..||.     .|   |||. |.. ||||| ||      
FWNKIGEGGYGQVYKGKW--RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

-NQNPQVSLSPTDLTIIAFGIASGMAYIHSRN--IIHRDLKTLNILLDSQ-----LLPKIIDFGTSSSNKSR---AIN--------QDVGTAAIMAPELH
 | |.   |..     .|  ||.|| |.|...  |||||||..|.|.|.      .  ||.|||.| .|...    .|          .|..  ||||. 
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

RF--EKYDQSVDVYSYGIILWEMLTHDI------PFGDKEPVQIVYCVAQ--KGERPILPNDVPIPLMKLINSCWAEDPKQRPAFSEICAKF
|   ..|....||||.||.|||..|..|      |. . .. |.   |..  .. || .||. |  . .||. ||. || ||| |.||  . 
RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 93567.m00048.AA Dicty5 89-277 41 6.8e-60 204.82 In-house 70-260 (260) Show / Hide 
Range on Protein: 89-277
Range on HMM: 70-260/260
Sequence Identity: 41% (81 aa)

NEKPLCIVTQYISNGSLYDALHNQNP---QVSLSPTDLTIIAFGIASGMAYIHSRNIIHRDLKTLNILLDSQLLPKIIDFGTSS-SNKSRAINQDVGTAA
|.| . .|| |..|||| ..|  |     |  . .. |  .| .|| .| ..|| |||||||| .|.|.   .  ||||||||           .||| .
NDKYPFHVTEYCHNGSLFNYLNDQRKTTGQPIAYFQQLH-MAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQC

IMAPELHRFEKYDQSVDVYSYGIILWEMLTHDIPFGDKEPVQIVYCVAQKGERPILPNDVPIPLMKLINSCWAEDPKQRPAFSEICAKFLSGE
 ||.||     |.| .||||.||.||||.| . |. .     |   | .||||| .| |.|    .|| .|| . |..|| | |||. | |  
WMACELFNGQPYHQKCDVYSFGIVLWEMFTRKEPYDNINNWNIPVMV-MKGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase 93567.m00048.AA S_TKc 26-274 25 1.4e-58 201.87 SMART 1-231 (231) Show / Hide 
Range on Protein: 26-274
Range on HMM: 1-231/231
Sequence Identity: 25% (66 aa)

LTFEKVIGSGGFGEVWIGNYIPSNTKVAIKKLFADELSEQTMSEISLHASLSQQFLVPFIGYTNEKPLCIVTQYISN--GSLYDALHNQNPQVS---LSP
 .. ..||.|.||.|. .  . .. .||||..      |....||... .    ..| ....  .. |..|. |...  |.|.| .......     ...
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE

TDLTIIAFGIASGMAYIHSRNIIHRDLKTLNILLDSQLLPKIIDFGTSSSNKSRAINQDVGTAAIMAPELHRFEKYDQ-SVDVYSYGIILWEMLTHDIPF
 .   ..  |.....|.||..|||||||  |||||.    ||.||| .        .  .||   ||||.    .|.  ..|..| |.||.|||.   ||
-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPF

GDKEPVQIVYCVAQKGERPILPNDVPIPLMKLINSCWAEDPKQRPAFSEICA--------KFL
     .| .. .             . ..  .|. |.  ||..||   |. .         ..
P---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 93567.m00048.AA Pkinase 26-273 23 4.1e-57 200.87 Pfam 1-293 (293) Show / Hide 
Range on Protein: 26-273
Range on HMM: 1-293/293
Sequence Identity: 23% (71 aa)

LTFEKVIGSGGFGEVWIGNYIPSNTKVAIKKLFADELSEQTM------SEISLHASLSQQFLVPFIGYT-NEKPLCIVTQYISNG----SLYDALH--NQ
......||||.||.|...  . .. .||.|..  .. ...        |||.....|.  . | ....  ... ...|. |  .|    .|.| ..  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NPQVSLSPTDLTIIAFGIASGMAYIHSRNIIHRDLKTLNILLDSQLLP----KIIDFGTSS---SNKSRAINQDVGTAAIMAPELHR-FEKYDQSVDVYS
..   .|. ..  ..  |..|..|.||..|||||||  |||.|..  .    ||.||| .      ...  .  .||   ||||..|  ..|...||..|
GCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

YGIILWEMLTHDIPFGDK----EPVQIVYCVAQKGERPILPND----------------------VPIPLMKLINSCWAEDPKQRPAFSEICAK--F
.|.||.|||.   || ..    . .   .........|.  .                       .. .. ..|..|.. |||.|| . .|.    |
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 93567.m00048.AA DRK 32-275 33 2.9e-55 185.63 In-house 7-258 (258) Show / Hide 
Range on Protein: 32-275
Range on HMM: 7-258/258
Sequence Identity: 33% (87 aa)

IGSGGFGEVWIGNYIPSNTKVAIKKLFADELS-EQTMSEISLHASLSQQF----LVPFIGYTNEKP-LCIVTQYISNGSLYDALHNQNPQVSLSPTDLTI
|| |..|||. |      |.||.|.||..    |  ..|    . |  |      . |.|  |. |  ||.. |.. ||||  ||..   ....   .  
IGRGNYGEVFRGTWR--GTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDE--SIEMDWPLMKQ

IAFGIASGMAYIHSRN--IIHRDLKTLNILLDSQLLPKIIDFGTSS----SNKSRAINQDVGTAAIMAPELHRFEKYDQSVDVYSYGIILWEMLTHDIPF
..| .| || | |..|  |||||||. | | |     |. ||| |          .    .||    |||  | . |    ||||..|.|||..|  .|.
MMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWECVTRQDPY

GDKEPVQIVYCVAQKGERPILPNDVPIPLMKLINSCWAEDPKQRPAFSEICAKFLS
  . . |.|  | . |.||. |  .| .  .|.| || ||| .|| . |.     .
FGMPTFQVVFSVGRHGMRPPMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase 93567.m00048.AA HH498 26-273 29 3.8e-53 166.63 In-house 1-284 (284) Show / Hide 
Range on Protein: 26-273
Range on HMM: 1-284/284
Sequence Identity: 29% (84 aa)

LTFEKVIGSGGFGEVWIGNYIPSNTKVAIKKLFADELSEQTM----------SEISLHASLSQQFLVPFIGYT--NEKPLCIVTQYISNGSLYDAL----
. | . |||| ||.|  | .   |  ||.|   |   ..              |.|.   |.    | |.. .   .. . |||||..||||.  |    
IEFHEKIGSGSFGKVYKGEWR--NKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYACCDDPSQFAIVTQYCDNGSLFSILNTIP

----------HNQN-PQVSLSPTDLTIIAFGIASGMAYIHS---RNIIHRDLKTLNILLDSQLLPKIIDFGTSSSNKSR---AINQDVGTAAIMAPELHR
          |||.     ...    .|.  .| || | |.   . ||||||   |||..     .. ||| |   ...    .    |    ||||   
IGGAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFS

-FEKYDQSVDVYSYGIILWEMLTHDIPFGDKEPVQIVYCVAQKGERPILPND----VPIPLMKLINSCWAEDPKQRPAFSEICAKF
   ||.  |||.||....|||.|  .|| . .|.     .| .  || .|.     .| .   ||  ||   |  || |..| .. 
QCQKYSIKVDVFSYAMCIWEMHTREVPFHHYKPAAAAAEMAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL
Kinase 93567.m00048.AA TK 26-273 16 3.1e-51 169.61 In-house 1-486 (486) Show / Hide 
Range on Protein: 26-273
Range on HMM: 1-486/486
Sequence Identity: 16% (81 aa)

LTFEKVIGSGGFG---EVWIGNYIPSN-------------------------TKVAIKKLF---ADELSEQTM----------------SEISLHAS--L
.|..|..|.| ||   ||. | ... |                         |.||.| |    |..  |. .                .|...  .  .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

SQQFLVPFIGYTNEK-------------PLCIVTQYISNGS----LYDALHNQNP---------------------------------------------
  . .| ..|.  ..             |..||. | ..|.    | | |..  |                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

--------QVSLSPTDLTI-------------------IAFGIASGMAYIHSR------NIIHRDLKTLNILLDSQLL-----------PKIIDFGTS--
          .|. .||                     ... ||.||.|.||.      |..|||| . |.|.....             || ||| |  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

-----------SSNKSRAINQDVG-------------------TAAI----MAPELHR---------FEKYDQSVDVYSYGIILWEMLTHD-IPFGDKEP
           ...  |. ....|                    . .    ||||  .         . |.    ||.|.|. .||..|.   |..   .
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

V---------QIVYCVAQK------------GERPILP--NDVPI-------------PLMKL-INSCWAEDPKQRPAFSEICAKF
          | |.   ..            |.|  .|   . |              ... . . .||..||..|| ||..  ..
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 93567.m00048.AA TyrKc 26-273 30 3.2e-50 174.07 SMART 1-280 (280) Show / Hide 
Range on Protein: 26-273
Range on HMM: 1-280/280
Sequence Identity: 30% (87 aa)

LTFEKVIGSGGFGEVWIGNYIPSNTKVAIKKLFADELSEQTMSEISLHASL--SQQFLVPFIGYTNE--------KPLCIVTQYISNGSLYDALHNQNPQ
.|..|..|.| ||||. | ..   ..||.|.| .|   |  |.|...  .|  . . .| ..|.  .        .||.||. | ..|.| | |..  |.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

VSLSPTDLTIIAFGIASGMAYIHSRNIIHRDLKTLNILLDSQLLPKIIDFGTSSSNKSR---AINQDVGTA-----AI-------MAPELHRFEKYDQSV
  |.. ||  ... ||.||.|.||.|.||||| . |.|.....  || ||| |   ..      ..|. ..     .        ||||  .. |.    
--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS

DVYSYGIILWEMLTH-DIPFGD-----KEPVQIVYCVAQKGERPILPND-------VPIPLMKLINSCWAEDPKQRPAFSEICAKF
||.|.|. .||..|  . |  .     ... ... .| | . .|. |||        |  . ... .||.|||..|| ||||. .|
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 93567.m00048.AA Dicty4-Unclassified 26-273 31 5.5e-50 169.38 In-house 1-263 (263) Show / Hide 
Range on Protein: 26-273
Range on HMM: 1-263/263
Sequence Identity: 31% (84 aa)

LTFEKVIGSGGFGEVWIGNYIPSNTKVAIKKL------FADELSEQTMSEISLHASLSQQFLVPFIGYTNEKP------LCIVTQYISNGSLYDALH---
.   . || | | .|  ||    .  ||.||.      | .|. .    |. .  |..   ||   ||    |      .|||.  .  | |    |   
IQIDQFIGKGHFSKVHKGNWKGKD--VAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCIN-PRSHKSTMCIVMEFMHKGNLFEVIHSKP

-NQNPQVSLSPTDLTIIAFGIASGMAYIHSRNIIHRDLKTLNILLDSQLLPKIIDFGTSSSNKSRAINQDVG-TAAIMAPELHRFEKYDQSVDVYSYGII
  |.  ..|  |    .|| || ||.. |.||.||||.|  |||.|     || ||| |           .. | .  .||  . | | |  |||||...
SEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMM

LWEMLTHDIPFGDKE-PVQIVYCVAQKGERPILPNDVPIPLMKLINSCWAEDPKQRPAFSEICAKF
|.|..| | |. .   .. .   |. |. || .|  ..  . |||  || .||. || . .|  . 
LYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase 93567.m00048.AA LRRK 91-275 34 8e-50 171.85 In-house 128-351 (351) Show / Hide 
Range on Protein: 91-275
Range on HMM: 128-351/351
Sequence Identity: 34% (78 aa)

KPLCIVTQYISNGSLYDALH--NQNPQ----VSLSPTDLTIIAFGIASGMAYIHSRN--IIHRDLKTLNILL---D---------SQLLPKIIDFGTSS-
.|||.|. |...|.||. ||   |...     ..|.. .  ||  ||.||.| ||.|  |||||||. ||||   .          .   ||.|||.|. 
HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRM

--SNKSRAINQDVGTAAIMAPELHRFE---KYDQSVDVYSYGIILWEMLTHD-IPFGD---KEPVQIVYCVAQ---KGERPILPND-VPI-----PLMKL
  . .. ...  ||.   ||||  |..    |.. ||.||.|.|||| || . .||..   .   |  . . .   .| || .|..  |       . .|
FQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDL

INSCWAEDPKQRPAFSEICAKFLS
|..||..|||.|| ||.|  .  .
IQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 93567.m00048.AA Pkinase_Tyr 26-166 32 8.9e-31 104.86 Pfam 1-156 (270) Show / Hide 
Range on Protein: 26-166
Range on HMM: 1-156/270
Sequence Identity: 32% (51 aa)

LTFEKVIGSGGFGEVWIGNYI----PSNTKVAIKKL--FADEL---SEQTMSEISLHASL-SQQFLVPFIGYTN--EKP--LCIVTQYISNGSLYDALHN
.|| |..|.| ||||. | .       ...||.|.|   |..    .|  |.|...  .| . . .| ..|     ..|  ..||. |  .|.|.| |..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

Q-NPQVSLSPTDLTIIAFGIASGMAYIHSRNIIHRDLKTLNILLDSQLLPKIIDFG
. ... .|.. ||  ... ||.||.| .|.|.||||| . |.|.....  || |||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase 93567.m00048.AA Pkinase_Tyr 186-273 31 1.2e-19 67.15 Pfam 181-270 (270) Show / Hide 
Range on Protein: 186-273
Range on HMM: 181-270/270
Sequence Identity: 31% (28 aa)

MAPELHRFEKYDQSVDVYSYGIILWEMLT-HDIP-FGDKEPVQIVYCVAQKGERPILPNDVPIPLMKLINSCWAEDPKQRPAFSEICAKF
||||  .. |.    ||.|.|. .||..|  ..| . .  . ...  ....|.|   | . | .. .|. .||..||..|| ||||  ..
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 93567.m00048.AA LRRK 26-57 23 2.4e-05 14.88 In-house 1-59 (351) Show / Hide 
Range on Protein: 26-57
Range on HMM: 1-59/351
Sequence Identity: 23% (14 aa)

LTFEKVIGSGGFG-EVWIGNYI--------------------------PSNTKVAIKKL
| .|. ||.|||| .|  ....                           . ..|||||.
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKW
Kinase 93567.m00048.AA Dicty5 26-45 40 0.187524 0.76 In-house 1-20 (260) Show / Hide 
Range on Protein: 26-45
Range on HMM: 1-20/260
Sequence Identity: 40% (8 aa)

LTFEKVIGSGGFGEVWIGNY
  | ..| ||  | |  | |
VSFHDWIASGASGRVYNGIY