83629.m00142

Species: T.vaginalis
Alias: 83629.m00142, TvagK0780
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
83629.m00142.AA Protein None 315 None Fasta, JSON
83629.m00142.kin_dom Protein Kinase Domain None 123 None Fasta, JSON

Protein domain

Protein domains of 83629.m00142.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 83629.m00142.AA CAMK 48-124 18 1.4e-17 52.53 In-house 202-336 (425) Show / Hide
Range on Protein: 48-124
Range on HMM: 202-336/425
Sequence Identity: 18% (25 aa)

HRDLKPDNIVVDGDM-----------------IPHIIDWDDSTDRFSLS-------------------------ISERHGTIPFAA-PEIFSA-------
||||||.|| .| ..                    |||.  ..  .. .                          ... || ...| ||...        
HRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQ

------QRK--CESDIFSFGAIMFNMITERYPFYS
      ..    ..|. | | |.. | . ..|||.
NATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYG

Kinase 83629.m00142.AA Ciliate-E2-Unclassified 1-124 22 5.3e-17 55.52 In-house 100-272 (352) Show / Hide
Range on Protein: 1-124
Range on HMM: 100-272/352
Sequence Identity: 22% (39 aa)

MDYIPGITITKLIS--------GGCVGNRIKKLCML-----------EIFAAIASQL-TLMKEMEIKHRDLKPDNIVVDGDM---IPHIIDWDDST----
|.|..| .  . |.        |.  ....|. ...            .|| | . |  | ..  | |||.||.||..| ..    . |||.  |     
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

---------DRFSLSISERH----GTIPFA----APEIFSA-QRK----CESDIFSFGAIMFNMITERYPFYS
          ...  ....     ||. .     |||..   .       ..||.|.| |.. |.. .||||.
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYD

Kinase 83629.m00142.AA Ciliate-E2 48-122 22 4.2e-15 48.29 In-house 184-296 (365) Show / Hide
Range on Protein: 48-122
Range on HMM: 184-296/365
Sequence Identity: 22% (26 aa)

HRDLKPDNIVVDGDMIPHIIDWDDSTDRFSLSISERH---------------------------------GTIPFAAPEIFSAQRK----------CESD
|||.||.||..     . |||.  |..    .. ..|                                 || .. ||||.. .             ..|
HRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCD

IFSFGAIMFNMITERYPF
|.|.| |.. |.. ..||
IWSLGVILYEMLFGKPPF

Kinase 83629.m00142.AA Pkinase 48-125 27 2.2e-11 41.3 Pfam 131-215 (293) Show / Hide
Range on Protein: 48-125
Range on HMM: 131-215/293
Sequence Identity: 27% (24 aa)

HRDLKPDNIVVDGDMIP----HIIDWDDST---DRFSLSISERHGTIPFAAPEI--FSAQRKCESDIFSFGAIMFNMITERYPFYSA
||||||.|| .| .. .    .|.|.  .       .   . . ||....|||.  ..     ..|..|.| |.. |.. | ||...
HRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGH

Kinase 83629.m00142.AA TKL 48-232 13 8.4e-09 27.84 In-house 163-364 (364) Show / Hide
Range on Protein: 48-232
Range on HMM: 163-364/364
Sequence Identity: 13% (34 aa)

HRDLKPDNIVVDGDMI--------------PHIIDWDDSTDRF---SLSISE------------------RHGTIPFAAPEIFSAQRK------------
|||||..|| || ..               . | |   |.. .   . . ..                  . ||. . |||..  | .            
HRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCK

-----CESDIFSFGAIMFNMITERYPFY-SAYRTRAGL-------QSLADKFSELQLPNLAETLDVLAEFEQMDDSEQYNHWPTVVSYVEPILTELIKAG
       .|..||| ... ..| . |.|   |... .           .||.  . .|.  ..                                     
GFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQN-------------------------------------

ARDDYIYNERFQNDPFNRKISELIGLCCKQEPDGRITPEDLHDRI
    .      ..... . ...|.  |....|. | . ... .|.
---HH-K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase 83629.m00142.AA Ciliate-A3 25-117 33 1.2e-08 24.84 In-house 77-176 (237) Show / Hide
Range on Protein: 25-117
Range on HMM: 77-176/237
Sequence Identity: 33% (33 aa)

LCMLEIFAAIASQLTLMKEMEIKHRDLKPDNIVV--DGDMIPHIIDWDDSTDRFSLSISERHGTIPFAAPEIFSAQRKCES-----DIFSFGAIMFNMIT
| ...|   |.  . ..||....||||||.||..  ||. |   |     |      .    .|  . |||| ||..|        |..||| |...| |
LEVIDIAIQITKGMMILKELNLEHRDLKPENILIHNDGEKIIAKISDYGLTKEVQCDLKSIVRTPNYMAPEILSAKKKGSVYDDKIDVWSFGLILYEMFT





Kinase 83629.m00142.AA S_TKc 3-236 12 6.8e-08 -61.19 SMART 1-231 (231) Show / Hide
Range on Protein: 3-236
Range on HMM: 1-231/231
Sequence Identity: 12% (39 aa)

YIPGITI-------------TK---------------------------------------------LISG--GCVGNRIKKLCM-----------LEIF
|  . .|             .|                                             ...|  | .  .|||                ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPEHARFYM

AAIASQLTLMKEMEIKHRDLKPDNIVVDGDMIPHIIDWDDSTDRFSLSISERHGTIPFAAPEIFSAQRKC-ESDIFSFGAIMFNMITERYPFYSAYRTRA
. |.. |  . .. | ||||||.|| .|      |.|   ..       .   ||  . |||..  .  . ..|. |.| |.. |.. . ||.       
YQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLCGYPPFP-------

GLQSLADKFSELQLPNLAETLDVLAEFEQMDDSEQYNHWPTVVSYVEPILTELIKAGARDDYIYNERFQNDPFNRKISELIGLCCKQEPDGRITPEDLHD
               .........                                                  .   ..|  |.. .|. |.|  ..  
---------------QMQMMFKKIG------------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQ

-----RIDSLA
     ...   
DEWDIKCHPWF

Kinase 83629.m00142.AA CAMKL 85-122 35 7.3e-08 21.02 In-house 195-236 (297) Show / Hide
Range on Protein: 85-122
Range on HMM: 195-236/297
Sequence Identity: 35% (15 aa)

GTIPFAAPEIFSA--QRKC--ESDIFSFGAIMFNMITERYPF
|. |..|||||.   .. .  . || | | |...|.. ..||
GSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPF

Kinase 83629.m00142.AA RIPK 48-122 27 1.9e-07 21.43 In-house 132-228 (290) Show / Hide
Range on Protein: 48-122
Range on HMM: 132-228/290
Sequence Identity: 27% (27 aa)

HRDLKPDNIVVDGDMIPHIIDWDDSTDR-FSLSISERH--------------GTIPFAAPEIFS---AQR----KCESDIFSFGAIMFNMITERYPF
|||||| || ||...   | |   .|..  | | ..|.              ||. . .|| |    . .      ..|. ||. .|.   | . |.
HRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNKKPIKVVTPKYDVYSFAIVMWEVLTQKHPY

Kinase 83629.m00142.AA Ciliate-E3 86-116 37 2.3e-07 19.35 In-house 171-202 (202) Show / Hide
Range on Protein: 86-116
Range on HMM: 171-202/202
Sequence Identity: 37% (12 aa)

TIPFAAPEIFS-AQRKCESDIFSFGAIMFNMI
|. .||||.   .| . |||. | ||..  ..
TPFYAAPEQNDQQQISKESDYYSVGAVFCQLC

Kinase 83629.m00142.AA AGC 85-124 34 3e-06 10.75 In-house 267-307 (395) Show / Hide
Range on Protein: 85-124
Range on HMM: 267-307/395
Sequence Identity: 34% (15 aa)

G--TIPFAAPEIFSAQRKCESDIFS--FGAIMFNMITERYPFYS
|  |  . ||||.      . |. |  .|..|. |.| . |||.
GPCTPEYMAPEIL---YGKACDWWSFGLGCLMYEMLTGYPPFYG

Kinase 83629.m00142.AA Ciliate-E9 40-59 45 5.6e-05 11.43 In-house 127-146 (298) Show / Hide
Range on Protein: 40-59
Range on HMM: 127-146/298
Sequence Identity: 45% (9 aa)

LMKEMEIKHRDLKPDNIVVD
. ..  | ||||||.|...|
MHQYQNICHRDLKPENMLID

Kinase 83629.m00142.AA CAMKL 48-68 47 0.000253 9.54 In-house 150-172 (297) Show / Hide
Range on Protein: 48-68
Range on HMM: 150-172/297
Sequence Identity: 47% (11 aa)

HRDLKPDNIVVDGDM--IPHIID
|||.||.|| .| ..     |||
HRDIKPENILLDENGNNNIKIID

Kinase 83629.m00142.AA AGC 48-68 50 0.000263 5.46 In-house 177-198 (395) Show / Hide
Range on Protein: 48-68
Range on HMM: 177-198/395
Sequence Identity: 50% (11 aa)

HRD-LKPDNIVVDGDMIPHIID
||| |||.||. | |   .. |
HRDYLKPENILLDEDGHIKLTD

Kinase 83629.m00142.AA Ciliate-E9 104-124 52 0.000493 8.35 In-house 207-227 (298) Show / Hide
Range on Protein: 104-124
Range on HMM: 207-227/298
Sequence Identity: 52% (11 aa)

DIFSFGAIMFNMITERYPFYS
|||| | | | |..  ||| .
DIFSAGCILFMMVMNQYPFFH

Kinase 83629.m00142.AA Ciliate-E3 48-59 75 0.022811 3.54 In-house 126-137 (202) Show / Hide
Range on Protein: 48-59
Range on HMM: 126-137/202
Sequence Identity: 75% (9 aa)

HRDLKPDNIVVD
| |.||||| ||
HSDIKPDNILVD