Gene 93242.m00143 (T.vaginalis)

93242.m00143

Species: T.vaginalis
Alias: TvagK0225, 93242.m00143
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
93242.m00143.AA Protein None 231 None Fasta, JSON
93242.m00143.kin_dom Protein Kinase Domain None 173 None Fasta, JSON

Protein domain

Protein domains of 93242.m00143.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 93242.m00143.AA CAMK 35-173 20 6.1e-45 142.31 In-house 195-425 (425) Show / Hide 
Range on Protein: 35-173
Range on HMM: 195-425/425
Sequence Identity: 20% (47 aa)

CHDFNIAHNDIKPSNFLLDQY-----------------GHVKICDFGLSKIYTE------------------------NPMSFDKKGSKYYMA-PEMFTN
||. ||.| |.|| | |||.                  . .||.|||.......                        ...  .  |. .||| ||..  
CHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNG

-------------GMYNPIVTDIWALGVTIYYLSTSTYPFDAE-------------TEEQLVEKINNCKYS-TEKIKDD---------------------
               | .  .|.|..||  | . . ..||...             ....| ||| ..||.  ..  ..                     
KGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFV

--RLRDLIARCLVVNPNERANVNELLNMPYF
    .||| ..|.|.|..|... . || | .
SQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 93242.m00143.AA AGC 24-173 20 2.2e-42 106.2 In-house 151-395 (395) Show / Hide 
Range on Protein: 24-173
Range on HMM: 151-395/395
Sequence Identity: 20% (51 aa)

YVFE-------MIGCIKVCHD-FNIAHND-IKPSNFLLDQYGHVKICDFGLSKI--------------------------------------YTENP---
|  |       .. ..   |.  .| | | .|| | |||. ||.|..||||.|.                                        .|    
YAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQ

----------MSFDKKG--SKYYMAPEMFTNGMYNPIVTDIWA--LGVTIYYLSTSTYPFDAET----------EEQLVEKINNCK-YSTEKIKDD----
          .     |  .  |||||..    |.. . |.|.  ||. .| . |   || ...          .... .|| |.. ....|.| .    
EDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKAC-DWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPED

-----------RLRDLIARCLVVNPNERAN----------VNELLNMPYF
            ..||| ..|...|..|            ..|. | |.|
PQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 93242.m00143.AA Ciliate-E2-Unclassified 1-173 24 2.3e-39 134.18 In-house 100-352 (352) Show / Hide 
Range on Protein: 1-173
Range on HMM: 100-352/352
Sequence Identity: 24% (61 aa)

MELCP----TDLMKLAKH----------------KISDSNLI-----KYVFEMIGCIKVCHDFN-IAHNDIKPSNFLLDQYG---HVKICDFGLSKIYTE
||.|.     . .|  |.                .... . .     .|  . . ... .|  | | | ||||.| |.|. |   ..||.|||.|| | .
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

N----------------PMSFDKKGSKYYM----APEMFTNGMYNP---IVTDIWALGVTIYYLSTSTYPFDAETEEQ----------------LVEKIN
|                 |. .. |. .||    |||.. .  |.    .  |||.||| .|.. . .|||.....||                | ..|.
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

NCKYSTEK--------IKDDRLRDLIA----RCLVVNPNERANVNELLNMPYF
.....  |        . ..   |.|     ..|..|||.| . ...|| |.|
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 93242.m00143.AA MARK 35-173 38 5.7e-39 125.14 In-house 120-262 (262) Show / Hide 
Range on Protein: 35-173
Range on HMM: 120-262/262
Sequence Identity: 38% (55 aa)

CHDFNIAHNDIKPSNFLLDQYG--HVKICDFGLSKIYTENPMSFDKKGSKYYMAPEMFTNGMYNPIVTDIWALGVTIYYLSTSTYPFDAET--EEQLVEK
||. ||.| |||| | |.|. |   .||.|||.| . ... .     |.. |||||.|    |.   .|||.|||  |.. . ..|||. |  ...| .|
CHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKK

INNCKYS-TEKIKDDRLRDLIARCLVVNPNERANVNELLNMPYF
|...||.   .. .. .|.|| | |.|||.||. . |... | .
ILRGKYDIPCHVSKE-CRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 93242.m00143.AA CAMKL 35-173 32 5.3e-38 118.75 In-house 143-297 (297) Show / Hide 
Range on Protein: 35-173
Range on HMM: 143-297/297
Sequence Identity: 32% (52 aa)

CHDFNIAHNDIKPSNFLLDQYG--HVKICDFGLSKIYTE-----NPMSFDKKGSKYYMAPEMFTN--GMYNPIVTDIWALGVTIYYLSTSTYPFDAET--
||. .|.| |||| | |||. |   .||.|||.| .|..     . .     ||  |||||.|      |.   .|||..||. | . . ..|||..|  
CHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYN

-----EEQLVEKINNCKYSTEKIK---DDRLRDLIARCLVVNPNERANVNELLNMPYF
        . .....|    . |    . ..|||| . |.|||..|... ...| | .
KQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 93242.m00143.AA Ciliate-E2 13-173 23 1e-37 127.05 In-house 133-365 (365) Show / Hide 
Range on Protein: 13-173
Range on HMM: 133-365/365
Sequence Identity: 23% (57 aa)

KHKIS-----DSNLIKYVFEMIG----------------CIKVCHDFN-IAHNDIKPSNFLLDQYGHVKICDFGLSKIYTEN-----------PMSFDK-
.|.|.     . . |||... |                 ... .|  | | | ||||.| |.     .||.||||||.|...            . | | 
NHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KN

---------------------KGSKYYMAPEMFTNGMY--------NPIVTDIWALGVTIYYLSTSTYPFDAETEEQLVEKINNCKYSTE----------
                      |. .|||||.. .. |             |||.|||..|.. .  .||         ..| .||..            
DTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQC

------KIKDDRLR--DLIAR----CLVVNPNERAN-VNELLNMPYF
      . |.  .   ||| .    .|...|..| .  ...|| |.|
IQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 93242.m00143.AA Pkinase 1-173 24 3.3e-36 129.11 Pfam 79-293 (293) Show / Hide 
Range on Protein: 1-173
Range on HMM: 79-293/293
Sequence Identity: 24% (54 aa)

MELCPTD--LMKLA-------KHKI--SDSNLIKYVFEMIGCIKVCHDFNIAHNDIKPSNFLLDQYGHV----KICDFGLSKI--YTENPMSFDKKGSKY
||.|. .  .| |.       . ..  |.  ...|. ...  .. ||. .| | |.||.|.|.|. ||.    |||||||.|   |  |.   .  |. .
MEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPW

YMAPEMFTNGMYNPIVTDIWALGVTIYYLSTSTYPFDAE------TEEQLVEKINNCKYSTEKIKD---------------------DRLRDLIARCLVV
|||||    | | .   |.|..|...|.. .   ||. .      .. |....|  .... .  ..                     . ..|.| .|| .
YMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCK

NPNERANVNELLNMPYF
.|..| .  ..|. |.|
DPKKRPTAEQILQHPWF
Kinase 93242.m00143.AA AMPK 35-173 37 1.2e-35 103.32 In-house 116-254 (254) Show / Hide 
Range on Protein: 35-173
Range on HMM: 116-254/254
Sequence Identity: 37% (52 aa)

CHDFNIAHNDIKPSNFLLDQYGHVKICDFGLSKIYTENPMSFDKKGSKYYMAPEMFTNGMYNPIVTDIWALGVTIYYLSTSTYPFDAETEEQLVEKINNC
||. .|.| | || | |||.  ..|| |||||...... .     ||  | |||| ..  |.   .|||  ||  | .   . ||| |   .|  || |.
CHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPFDDENTPTLYKKIKNG

KYSTEKIKDDRLRDLIARCLVVNPNERANVNELLNMPYF
.|.. |   .. .||| . | |.|..|...... | |.|
EYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 93242.m00143.AA CAMKK 32-173 28 2.2e-34 106.19 In-house 210-396 (396) Show / Hide 
Range on Protein: 32-173
Range on HMM: 210-396/396
Sequence Identity: 28% (53 aa)

IKVCHDFNIAHNDIKPSNFLLDQYG---HVKICDFGLSKIY-TENPMSFD-----------KKGSKYYMAPEMFTNGM---------------YNPIVTD
| . |   | | ||||.| |.|. |   ||||.||| |.|  .... ...             | ...||||.....                |.    |
I-IDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVSHIFEGQDQTLSNCESCFQRELNKTAGTPAFMAPELCSKENQKENYNGYKYRFRFIYCGKAAD

IWALGVTIYYLSTSTYPFDAETEEQLVE---KI--NNCKYST-----------EKIKDDRLRDLIARCLVVNPNERANVNELLNMPYF
|||||||.|.. . . || .....|| .   ||  .. |. .           .    . | ||| |.|  || .| .. .... | .
IWALGVTLYCFVFGKCPFWHNNLMQLHHNYMKIKNDPIKFPENKEMLNNVSIYCPEISEDLKDLIKRMLEKNPTKRITIPQIKVHPWV
Kinase 93242.m00143.AA ULK 1-173 24 2.9e-30 102.87 In-house 99-329 (329) Show / Hide 
Range on Protein: 1-173
Range on HMM: 99-329/329
Sequence Identity: 24% (56 aa)

MELCPT-DLMKLAKHK------------ISDSNLIKYVFEMIGCIKVCHDFNIAHNDIKPSNFLLDQY------------GHVKICDFGLSKIYTEN---
||.|.  ||... | .            .| .  |..    .   |  |. || | ||||.| |..              |..||.|||..|  ...   
MEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNME

-PMSFDKK------GSKYYMAPEMFT----NGMYNPIVTDIWALGVTIYYLSTSTYPFDAETEEQLV-----EKINN------------CKYS---TEKI
  |    .      |. .||||. .     .  |.   .||| ||. .|.. .  .|| |   ....     . |||             ..     ...
QQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQ

KDDRLRDLIARCLVVNPNERANVNELLNMPYF
  . ..||| |.|......| .  ||.|.| |
ISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 93242.m00143.AA ULK 1-173 24 1.2e-29 102.35 In-house 96-324 (324) Show / Hide 
Range on Protein: 1-173
Range on HMM: 96-324/324
Sequence Identity: 24% (57 aa)

MELCPT-DLMKLAKHK-----------ISDSNLIKYVFEMIGCIKVCHDFNIAHNDIKPSNFLLDQY------------GHVKICDFGLSKIYTENPMSF
||.|.  || .. | .           .| .  |..    .   |  |. || | ||||.| |.               |..||.|||..|.  .| |. 
MEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQ

DKK----------GSKYYMAPEMFT----NGMYNPIVTDIWALGVTIYYLSTSTYPFDAETEEQLV----EKINN-------CKYSTEKIKD--------
..           |. .||||. .     .  |. . .||| ||. .|.. .  ||| .   ....    . |||        |.   ....        
QMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKIS

DRLRDLIARCLVVNPNERANVNELLNMPYF
. ..||| |.|......| .  |..|.| |
PECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 93242.m00143.AA S_TKc 1-173 19 9.8e-16 53.81 SMART 1-231 (231) Show / Hide 
Range on Protein: 1-173
Range on HMM: 1-231/231
Sequence Identity: 19% (50 aa)

M-----------------------------------------------------------------ELCPT---DLMKLAKHK--------ISDSNLIKY
                                                                  |.|..   ||... |..        ..     .|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFY

VFEMIGCIKVCHDFNIAHNDIKPSNFLLDQYGHVKICDFGLSKIYTENPMSFDKKGSKYYMAPEMFTNGMYNPIVTDIWALGVTIYYLSTSTYPFDAETE
. ...  .. ||. .| | |.||.| |||.  |.|||||||....          |. .|||||..    |..   |.|..|...| . .   ||.  ..
MYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QM

EQLVEKINNCKYSTEKIKDDRLRDLIARCLVVNPNERANVNELLN-------MPYF
... .||           .. ..|.| .||...|..|  . |.|.       .|.|
QMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 93242.m00143.AA TyrKc 6-173 13 1e-05 -129.72 SMART 1-280 (280) Show / Hide 
Range on Protein: 6-173
Range on HMM: 1-280/280
Sequence Identity: 13% (40 aa)

TDLM----------------------KLAK--------------HKI--SDSNLIKYVFEMIGCIKV----------------------CHDFNIAHN--
  |                       |  |              .|.  .  |...    ..|..                        ..|.  .|   
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVR----LYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

----------------------------DIKPSNFLLDQYGHVKICDFGLSKIYTEN------PMSFDKK---GSK-----YYMAPEMFTNGMYNPIVTD
                            |.   | |..  ..|||.|||||.  ..           .||   |.|       |||| .  |... . .|
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-TKSD

IWALGVTIYYLSTSTYPFDAE------TEEQLVEKINNCKYSTEKIK---------DDRLRDLIARCLVVNPNERANVNELLNMPYF
.|. ||... . |   .   .      . ....|.. . ..                | . ... .|   .|..| . .|.    .|
VWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF