85805.m00060

Species: T.vaginalis
Alias: 85805.m00060, TvagK0183
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
85805.m00060.AA Protein None 169 None Fasta, JSON
85805.m00060.kin_dom Protein Kinase Domain None 168 None Fasta, JSON

Protein domain

Protein domains of 85805.m00060.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 85805.m00060.AA CAMK 1-164 18 8e-35 109.11 In-house 136-414 (425) Show / Hide
Range on Protein: 1-164
Range on HMM: 136-414/425
Sequence Identity: 18% (52 aa)

M---EYCPFD------LERIVLSNRN--------------MQPAEIKKYCREAVLCIKACHDMNIAHCDIKPANFMTDEY-----------------GRL
|   |||.        ...||   ..              .. .| ..| |  .  .. ||..||.|.|.|| | . |.                  . .
MEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNI

KIGDFGLATIFKDSH------------------------VRNIYSGTKIMMA-PEIYEQ-------------NGYDAMAADIWALGCTLYFIATGRYPFF
|| |||.|..|....                          . . ||   || ||. ..             . |.  ..|.|..|. ||.  .|..|| 
KIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFY

VV-------------DPRELVQLISLAKYD-GSLIKDK-----------------------LLRDVIARCLRIEPKDRL
               ...|| . |  .|||  .   ..                         .| | ..|. .|..|.
GDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRM

Pkinase 85805.m00060.AA Pkinase 1-165 25 1.5e-33 119.66 Pfam 79-283 (293) Show / Hide
Range on Protein: 1-165
Range on HMM: 79-283/293
Sequence Identity: 25% (53 aa)

MEYCPF-----DLERIVL--SNRNM--QPAEIKKYCREAVLCIKACHDMNIAHCDIKPANFMTDEYGRL----KIGDFGLATI--FKDSHVRNIYSGTKI
||||.      || ...   .....  .. |.|.|... .  .. ||.|.| |.|.||.|.. |. | .    ||.|||||       ..  . . ||  
MEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPW

MMAPEIYE-QNGYDAMAADIWALGCTLYFIATGRYPFFVV------DPRELVQLISLAKYDGSLIKD---------------------KLLRDVIARCLR
 ||||.   ...|.  ..|.|..||.||  ..|| ||         |.......|  .... .  ..                     . ..|.| .||.
YMAPEVIRGGQYYGP-KVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLC

IEPKDRLG
  ||.|..
KDPKKRPT

Kinase 85805.m00060.AA CAMKL 1-121 32 7.3e-29 89.12 In-house 100-236 (297) Show / Hide
Range on Protein: 1-121
Range on HMM: 100-236/297
Sequence Identity: 32% (45 aa)

MEYCP---FDLERIVLSNRN----MQPAEIKKYCREAVLCIKACHDMNIAHCDIKPANFMTDEYG--RLKIGDFGLATIFKD-----SHVRNIYSGTKIM
||||.    ||   . ....    |.. | ..| |  |  .. ||...|.| |||| | . || |   .|| |||.......      .  ..  |.   
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

MAPEIYEQ--NGYDAMAADIWALGCTLYFIATGRYPF
|||||..     ||. ..|||..| .||.. .|..||
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPF

Kinase 85805.m00060.AA MARK 37-163 40 1.2e-27 87.54 In-house 120-250 (262) Show / Hide
Range on Protein: 37-163
Range on HMM: 120-250/262
Sequence Identity: 40% (53 aa)

CHDMNIAHCDIKPANFMTDEYG--RLKIGDFGLATIFKDSHVRNIYSGTKIMMAPEIYEQNGYDAMAADIWALGCTLYFIATGRYPFF--VVDPRELVQL
||..||.|.|||| | . || |    || |||......     |.  ||.  ||||| ..  ||. ..|||.||  |||. .|..||    .|  || . 
CHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKK

ISLAKYDGSLIKDKLLRDVIARCLRIEPKDR
|   |||      | .|. | | | . |..|
ILRGKYDIPCHVSKECRNLIQRLLTVNPEER

Kinase 85805.m00060.AA ULK 1-163 24 4.7e-26 88.0 In-house 99-317 (329) Show / Hide
Range on Protein: 1-163
Range on HMM: 99-317/329
Sequence Identity: 24% (54 aa)

MEYCPF-DLERIVLSNRN----------MQPAEIKKYCREAVLCIKACHDMNIAHCDIKPANFMTDEY------------GRLKIGDFGLATIFKDS---
||||.  ||| .   |..              |......  .   |. |..|| |.||||.| . ..             |.|||.|||.|  . ..   
MEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNME

-HVRNIYS------GTKIMMAPEIYEQNG----YDAMAADIWALGCTLYFIATGRYPFFVVDPRELV-----QLISL------------AKYD---GSLI
  .   ..      || . |||.| ...|    |.   .||| ||| .| . .|..||.   .....     .|| .             ...    . .
QQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQ

KDKLLRDVIARCLRIEPKDR
  . ..| | |.| ...|||
ISPECKDLIRRMLQYDEKDR

Kinase 85805.m00060.AA STE 1-163 23 2e-25 86.84 In-house 116-345 (359) Show / Hide
Range on Protein: 1-163
Range on HMM: 116-345/359
Sequence Identity: 23% (55 aa)

MEYCPF-DLERIVLSNRNMQP--------------AEIKKYCREAVLC-IKACHDMNIAHCDIKPANFMTDEYGRLKIGDFGLATIFKDSH---------
|||..   |. |. ..  ..                .|...||. .    .  |...| | |||||| .       |. |||..... ||.         
MEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNII

--------VRNIYSGTKIMMAPEIYEQ------NGYDAMAADIWALGCTLYFIATGRYPFFVVDPRELVQLISLAK-------------YDGSLIKD---
         ||   ||   ||||. .|      .|||.  .||| ||||.   |||..|..   | .   .|   .              .   ..|   
DCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDT-KCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLS

-------------------KLLRDVIARCLRIEPKDR
                   . ..| |..||...|..|
QNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKR

Kinase 85805.m00060.AA Ciliate-E2-Unclassified 1-165 20 3e-25 84.57 In-house 100-342 (352) Show / Hide
Range on Protein: 1-165
Range on HMM: 100-342/352
Sequence Identity: 20% (51 aa)

MEYCP-FDLERIVLS------------NRNMQ-----PAEIK-----KYCREAVLCIKACHDMN-IAHCDIKPANFMTDEYG---RLKIGDFGLATIFK-
||||.  ||. .  .            ....|       ..|     .|... ..... .|  | | | |||| | . |. |   ..|| |||..   . 
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

----DSHV---------RNIY---SGTKIMM----APEIYEQNGYDAM---AADIWALGCTLYFIATGRYPFFVVDPRE---------------LVQLIS
    | .          ....   .|| . |    |||......|| .   ..|||.||. ||.. .|.|||.  .  .                .. . 
NNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

LAK-------------YDGSLIKDKLLRDVIARCLRIEPKDRLG
..|             .. |     ...| . ..|   |. |..
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRIT

Kinase 85805.m00060.AA Ciliate-E2 26-165 22 5.1e-25 82.82 In-house 165-354 (365) Show / Hide
Range on Protein: 26-165
Range on HMM: 165-354/365
Sequence Identity: 22% (46 aa)

YCREAVLCIKACHDMN-IAHCDIKPANFMTDEYGRLKIGDFGLATIFKDSHVRNIY--------------------------------SGTKIMMAPEIY
|... .|... .|  | | | |||| | .      .|| ||||.....|.. ....                                 ||   |||||.
YIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEIL

EQNGYDA--------MAADIWALGCTLYFIATGRYPFFVVDPRELVQLISLAKYDGSLIK------------------DKLLRDVIAR----CLRIEPKD
.  .||          ..|||.||..||.  .|..||         | |   |.| .  .                  ..   | | .    .|  .|. 
NGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEK

RLG
|..
RIT

Kinase 85805.m00060.AA CAMKK 24-122 28 6.7e-25 75.59 In-house 179-327 (396) Show / Hide
Range on Protein: 24-122
Range on HMM: 179-327/396
Sequence Identity: 28% (43 aa)

KKYCREAVLCIKACH-DMN-------------------IAHCDIKPANFMTDEYG---RLKIGDFGLATIFKDSHVRNIY------------SGTKIMMA
.|| |. .. .. .| . .                   | | |||| |   || |   ..|| ||| ..||.... ...              ||.  ||
WKYFRDCIKGLEYLHNYQKACSYIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVSHIFEGQDQTLSNCESCFQRELNKTAGTPAFMA

PEIYEQ-NG--------------YDAMAADIWALGCTLYFIATGRYPFF
||  .  |.              |.  ||||||||.||| . .|. ||.
PELCSKENQKENYNGYKYRFRFIYCGKAADIWALGVTLYCFVFGKCPFW

Kinase 85805.m00060.AA ULK 1-163 25 1.1e-23 80.94 In-house 96-312 (324) Show / Hide
Range on Protein: 1-163
Range on HMM: 96-312/324
Sequence Identity: 25% (56 aa)

MEYCPF-DLERIVLSNRN---------MQPAEIKKYCREAVLCIKACHDMNIAHCDIKPANFMTDEY------------GRLKIGDFGLATIFKDS----
||||.  ||| .   |..             |......  .   |. |..|| |.||||.| .  .             |.|||.|||.| .. .     
MEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQ

HVRNIYS------GTKIMMAPEIYEQNG----YDAMAADIWALGCTLYFIATGRYPFFVVDPRELV----QLISL------AKYDGSLIKD---------
 ..  .       || . |||.| ...|    |.   .||| ||| .| . .|.||||   .....    .||          ..  . ..         
QMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKIS

KLLRDVIARCLRIEPKDR
. ..| | |.| ...|||
PECKDLIRRMLQYDEKDR

Kinase 85805.m00060.AA CAMKK-Unclassified 24-129 24 4.6e-23 71.7 In-house 181-341 (392) Show / Hide
Range on Protein: 24-129
Range on HMM: 181-341/392
Sequence Identity: 24% (40 aa)

KKYCREAVLCIKACHDMN---------------------IAHCDIKPANFMTDEYGR-----LKIGDFGLATIFKDSHVR--NIYSGTKIMMAPEIYEQN
||| |.  . .. .|. |                     | | |||| |   |. ..     .|| |||...|..... .  .   ||.  ||||  . .
KKYFRQCCKGLQYMHNFNQACSYIIIYINEFDKIDHFQDIIHRDIKPQNILIDHEDNDKGEHFKIADFGISVIMEHEQQKKLKNNAGTYCFMAPEFWSKE

--GYDAMA-------------------------ADIWALGCTLYFIATGRYPFFVVDPREL
  .||  .                         ||||.|| |.| ..... ||.  .. ||
NFKYDYNDYSFLPGTFNPLRKTYRIERICFYKKADIWSLGVTFYCMVYHSLPFWHKNLQEL

Kinase 85805.m00060.AA S_TKc 1-169 18 3e-14 32.07 SMART 1-231 (231) Show / Hide
Range on Protein: 1-169
Range on HMM: 1-231/231
Sequence Identity: 18% (47 aa)

M-----------------------------------------------------------------EYCPF---DLERIVLSNRN------MQPAEIKKY
                                                                  |||.    || ..  ...       . . ....|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFY

CREAVLCIKACHDMNIAHCDIKPANFMTDEYGRLKIGDFGLATIFKDSHVRNIYSGTKIMMAPEIYEQNGYDAMAADIWALGCTLYFIATGRYPFFVVDP
... .. .. ||...| |.|.||.| . ||  ..||.|||||...      . . ||   ||||.    ||.  ..|.|..||.||  ..|. ||   ..
MYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QM

RELVQLISLAKYDGSLIKDKLLRDVIARCLRIEPKDRLG------------DAIL
 .. ..|           .. ..| | .||. .|..|..            .  .
QMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF