Gene 89915.m00027 (T.vaginalis)

89915.m00027

Species: T.vaginalis
Alias: TvagK0206, 89915.m00027
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
89915.m00027.AA Protein None 232 None Fasta, JSON
89915.m00027.kin_dom Protein Kinase Domain None 176 None Fasta, JSON

Protein domain

Protein domains of 89915.m00027.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 89915.m00027.AA CAMK 1-176 18 5.7e-48 152.25 In-house 136-425 (425) Show / Hide 
Range on Protein: 1-176
Range on HMM: 136-425/425
Sequence Identity: 18% (54 aa)

M---EYCPSD------LEKFLSERQ-------------KYTSPCLIQNTLSEVAKCVKACHDHKIAHCDIKPSNFLVDKY-----------------GRL
|   |||.        ...  . ..             .. .    .     ..  |. ||.|.|.|.|.|| | |.|.                  . .
MEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNI

KIADFGMATMCNRSK------------------------PSASFHGTLLFMA-PEIFGI-------------NYYNPSTADIWAMGVTMYYIVTGQYPFN
||.|||.|.......                        .   | ||. .|| ||..               . | .  .|.|..|| .|  ..| .||.
KIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFY

GL-------------DQRAVKDSVEKGIYN-QEPVRDS-----------------------LLRDLISRCLETDLMYRATIDEVLSHPYF
|              ...  .  . || |.  .|  .                          .|||...|..|   |.||...|.|| .
GDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 89915.m00027.AA CAMKL 38-176 32 1.5e-47 149.69 In-house 143-297 (297) Show / Hide 
Range on Protein: 38-176
Range on HMM: 143-297/297
Sequence Identity: 32% (51 aa)

CHDHKIAHCDIKPSNFLVDKYG--RLKIADFGMATMCNR-----SKPSASFHGTLLFMAPEIFGI--NYYNPSTADIWAMGVTMYYIVTGQYPFNGL---
||.|.|.| |||| | |.|. |   .||.|||...|. .      .    | |.. .||||||      |.   .|||..||..| .|.|..||..    
CHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYN

-----DQRAVKDSVEKGIYNQ-EPVRDSLLRDLISRCLETDLMYRATIDEVLSHPYF
     ..   .  . .| |.   ... | .||||.. |... ..|.||.....|| .
KQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 89915.m00027.AA MARK 38-176 35 3e-44 142.64 In-house 120-262 (262) Show / Hide 
Range on Protein: 38-176
Range on HMM: 120-262/262
Sequence Identity: 35% (51 aa)

CHDHKIAHCDIKPSNFLVDKYG--RLKIADFGMATMCNRSKPSASFHGTLLFMAPEIFGINYYNPSTADIWAMGVTMYYIVTGQYPFNGLD--QRAVKDS
||.. |.|.|||| | |.|. |    ||.|||... ..  .   .| ||. .||||||    |.   .|||..|| .|..|.|..|| | .  .   .  
CHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKK

VEKGIYNQEPVRDSLLRDLISRCLETDLMYRATIDEVLSHPYF
. .| |   .     .|.||.| | .. ..|.||.|...|| .
ILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 89915.m00027.AA AGC 1-176 18 2.2e-41 103.53 In-house 112-395 (395) Show / Hide 
Range on Protein: 1-176
Range on HMM: 112-395/395
Sequence Identity: 18% (54 aa)

MEYCP---------SDLEKFLSE----RQKYTSPCLIQNTLSE-------VAKCVKACHD-HKIAHCD-IKPSNFLVDKYGRLKIADFGMATMCNRS---
|||.|          ..| ||.     .... .   ..  ..|       .. ..   |. ..| | | .|| | | |. | .|..|||.... ...   
MEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEK

------------------------------------------------KPSASFHG--TLLFMAPEIFGINYYNPSTADIWA--MGVTMYYIVTGQYPFN
                                                .   .| |  |  .|||||.    |... .|.|.  .|. ||  .||. ||.
GQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKA-CDWWSFGLGCLMYEMLTGYPPFY

GL----------DQRAVKDSVEKGIY--NQE--------------PVRDSLLRDLISRCLETDLMYRAT----------IDEVLSHPYF
|           ..  . .....|.|  |..              .  .. ..|||...|. |   | .          ..|. .||.|
GDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 89915.m00027.AA Pkinase 1-176 25 1.4e-40 144.6 Pfam 79-293 (293) Show / Hide 
Range on Protein: 1-176
Range on HMM: 79-293/293
Sequence Identity: 25% (55 aa)

MEYCPS-----DLEKFLS-ERQKYT--SPCLIQNTLSEVAKCVKACHDHKIAHCDIKPSNFLVDKYGRL----KIADFGMATM--CNRSKPSASFHGTLL
||||.      ||  ..| .|..    |.  ... . .... .. ||...| |.|.||.|.|.|. | .    ||.||| |      ..    .| ||. 
MEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPW

FMAPEIFGINYYNPSTADIWAMGVTMYYIVTGQYPFNGL------DQRAVKDSVEKGIYNQEPVRD---------------------SLLRDLISRCLET
.||||.   . | .. .|.|..|...|. ..|. || |       ||... . . ....  .   .                     . ..|.|..||. 
YMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCK

DLMYRATIDEVLSHPYF
|   | |....| ||.|
DPKKRPTAEQILQHPWF
Kinase 89915.m00027.AA ULK 1-176 25 4.4e-36 123.48 In-house 99-329 (329) Show / Hide 
Range on Protein: 1-176
Range on HMM: 99-329/329
Sequence Identity: 25% (59 aa)

MEYCPS-DLEKFLSERQK---------YTSPCLIQNTLSEVAKCVKACHDHKIAHCDIKPSNFLVDKY------------GRLKIADFGMATMCNRS---
||||.  |||.......|         . |   ... .   .   |. |.|.| |.||||.| |...             |.||||||| | ... .   
MEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNME

---KPSAS----FHGTLLFMAPEIFG----INYYNPSTADIWAMGVTMYYIVTGQYP----FNGLDQRAVKDSVEKG------IYNQEPV---------R
     ...    . || |.|||.|.        |. ...||| .|. .|....|..|    || .. . ... ....      | .| .          .
QQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQI

DSLLRDLISRCLETDLMYRATIDEVLSHPYF
 . ..|||.|.|. |   | ...|...|| |
SPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 89915.m00027.AA Ciliate-E2 1-176 19 8.4e-36 120.36 In-house 113-365 (365) Show / Hide 
Range on Protein: 1-176
Range on HMM: 113-365/365
Sequence Identity: 19% (52 aa)

MEYCPS-DLEKFLSERQKYTSPC----------LIQNTLSEVAK---------------CVKACHDHK-IAHCDIKPSNFLVDKYGRLKIADFGMAT---
||||   ||.... ...|    .           |..   ....               ... .|  . | | ||||.| |.     .||.|||...   
MEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYD

-------------MCNRSK-----------------PSASFHGTLLFMAPEIFGINYY--------NPSTADIWAMGVTMYYIVTGQYPFNGLDQRAVKD
             ..   |                    .. ||. .|||||..   |            .|||..||..|. ..|..||         .
DDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQ

SVEKGIYNQE-----------------PVRDSLL-RDLISR----CLETDLMYRAT-IDEVLSHPYF
  ... ..                   .   |.   |||..    .|. |   | | ....| ||.|
QIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 89915.m00027.AA ULK 1-176 26 1.4e-35 123.68 In-house 96-324 (324) Show / Hide 
Range on Protein: 1-176
Range on HMM: 96-324/324
Sequence Identity: 26% (62 aa)

MEYCPS-DLEKFLSERQK--------YTSPCLIQNTLSEVAKCVKACHDHKIAHCDIKPSNFLVDKY------------GRLKIADFGMATMCN---RSK
||||.  |||... ...|        . |   ... .   .   |. |.|.| |.||||.| |. .             |.||||||| | ...    ..
MEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQ

PSA-SFH------GTLLFMAPEIFG----INYYNPSTADIWAMGVTMYYIVTGQYP----FNGLDQRAVKDSVEKG------IYN---------QEPVRD
    ..       || |.|||.|.        |. . .||| .|. .|....|.||    || .... ... ...|      |.|         ..|.. 
QMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPPKDPKIS

SLLRDLISRCLETDLMYRATIDEVLSHPYF
. ..|||.|.|. |   | ...|...|| |
PECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 89915.m00027.AA Ciliate-E2-Unclassified 1-176 20 2.5e-34 116.48 In-house 100-352 (352) Show / Hide 
Range on Protein: 1-176
Range on HMM: 100-352/352
Sequence Identity: 20% (51 aa)

MEYCPS-DLEKFLSE------------RQKYTSPCL----IQ-----NTLSEVAKCVKACHDHK-IAHCDIKPSNFLVDKYG---RLKIADFGMAT----
||||.  ||......            ...... ..    ..     . . .. .. . .|  . | | ||||.| |.|. |   ..||.||| .     
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

------------MCNRSKPSASFHGTLLFM----APEIFGI-NYYNPST--ADIWAMGVTMYYIVTGQYPFNGLDQRA------------VKDSVEKGIY
              .... . .| ||. .|    |||...  ||....   .|||..|| .|....|.|||.. ..              ..  ... |.
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

NQEPVRDS----------------LLRDLISRCLETDLMYRATIDEVLSHPYF
....  ..                ...||....|. .. .| |....| ||.|
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 89915.m00027.AA CAMKK-Unclassified 30-176 23 1.3e-31 100.03 In-house 186-392 (392) Show / Hide 
Range on Protein: 30-176
Range on HMM: 186-392/392
Sequence Identity: 23% (48 aa)

EVAKCVKACHDHK---------------------IAHCDIKPSNFLVDKYGR-----LKIADFGMATMCNRSKPS--ASFHGTLLFMAPEIFGIN--YYN
...| .. .|. .                     | | |||| | | |. ..     .|||||| ...   .. .   .  ||. ||||| .  .   |.
QCCKGLQYMHNFNQACSYIIIYINEFDKIDHFQDIIHRDIKPQNILIDHEDNDKGEHFKIADFGISVIMEHEQQKKLKNNAGTYCFMAPEFWSKENFKYD

PST-------------------------ADIWAMGVTMYYIVTGQYPFNGLDQRAVKD-SVEKGI-YNQ---EPVRDSLLRDLISRCLETDLMYRATIDE
..                          ||||. ||| |..|..  ||.. .    .    ....  .    .|    .. ||| .... . . |.||| 
YNDYSFLPGTFNPLRKTYRIERICFYKKADIWSLGVTFYCMVYHSLPFWHKNLQELFHQMICQKEINFPPQYHPHCSHEFKDLIQKMCDKNPKKRITIDQ

VLSHPYF
.| ||.|
MLVHPWF
Kinase 89915.m00027.AA CAMKK 38-176 27 1.3e-31 97.23 In-house 192-396 (396) Show / Hide 
Range on Protein: 38-176
Range on HMM: 192-396/396
Sequence Identity: 27% (56 aa)

CH-DHK-------------------IAHCDIKPSNFLVDKYG---RLKIADFGMATMCNRSKPSASF------------HGTLLFMAPEIFGI-NY----
.| . |                   | | ||||.| |.|. |   ..|||||| ...   .... |              ||  ||||| .   |     
LHNYQKACSYIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVSHIFEGQDQTLSNCESCFQRELNKTAGTPAFMAPELCSKENQKENY

----------YNPSTADIWAMGVTMYYIVTGQYPFNGLDQRAVKDSVEKGIYNQEPVRDS-----------------LLRDLISRCLETDLMYRATIDEV
          |.   |||||.||| |..|.|. ||.. .  . ..   | | |....  .                 .| ||| |.|| . . | ||...
NGYKYRFRFIYCGKAADIWALGVTLYCFVFGKCPFWHNNLMQLHHNYMK-IKNDPIKFPENKEMLNNVSIYCPEISEDLKDLIKRMLEKNPTKRITIPQI

LSHPYF
..|| .
KVHPWV
Kinase 89915.m00027.AA S_TKc 1-176 19 4.3e-19 70.68 SMART 1-231 (231) Show / Hide 
Range on Protein: 1-176
Range on HMM: 1-231/231
Sequence Identity: 19% (50 aa)

M-----------------------------------------------------------------EYCPS---DLEKFLSERQK-----YTSPCLIQNT
                                                                  |||.    || ... .|..     . ..  ..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFY

LSEVAKCVKACHDHKIAHCDIKPSNFLVDKYGRLKIADFGMATMCNRSKPSASFHGTLLFMAPEIFGINYYNPSTADIWAMGVTMYYIVTGQYPFNGLDQ
. .... .. ||.|.| |.|.||.| |.|.  ..||.|||.|.         .| ||. .||||..    |..  .|.|. |...|  ..|. ||   ..
MYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QM

RAVKDSVEKGIYNQEPVRDSLLRDLISRCLETDLMYRATIDEVLS-------HPYF
 .. . .           .. ..|.|..||. |   | |. |.|        ||.|
QMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 89915.m00027.AA TyrKc 1-176 15 0.000147 -148.92 SMART 1-280 (280) Show / Hide 
Range on Protein: 1-176
Range on HMM: 1-280/280
Sequence Identity: 15% (43 aa)

M--------------------------------------------EY--------------CPS--------------------DLEKFLSERQKYTSPC
                                             ..                .                    || ..| ....  .. 
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

LIQNTLSEVAKCVKACHDHKIAHCDIKPSNFLVDKYGRLKIADFGMATMCNRS------KPSASF----HGTLLF----MAPEIFGINYYNPSTADIWAM
   .    .|.     |.... | |.   | ||.. .. ||.|||..            |   .     .|  ..    |||| .  . ... . |.|. 
DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS-DVWSF

GVTMYYIVT-GQYPFNG-----LDQRAVKDSVEKGIYNQEPVR---------DSLLRDLISRCLETDLMYRATIDEVLSHPYF
||.|. | | || |  |     .. . |   |..| .   |            . . .....| . |   | |  |.  | .|
GVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF