Gene 91127.m00275 (T.vaginalis)

91127.m00275

Species: T.vaginalis
Alias: 91127.m00275, TvagK0315
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
91127.m00275.AA Protein None 979 None Fasta, JSON
91127.m00275.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of 91127.m00275.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 91127.m00275.AA TKL 101-347 24 1.7e-82 280.42 In-house 1-364 (364) Show / Hide 
Range on Protein: 101-347
Range on HMM: 1-364/364
Sequence Identity: 24% (93 aa)

LGAGGFGTVSKATLKRTS--------EFVAVKKIRYDKLSPKAWQSIWD-------------------------EITLMKKLHHPCILELVGAQIHEP--
.| ||||.| |.... ..        . |||||.. .  . . ..| ..                         || .|..|.|| |. ..|. . .|  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YCIITRFCSGRSLFDRLHRQKTNQLPALQPTELTKIAYQIALGMEYLHAQK--------IVHRDLKTLNILLDDKNN-----------
            .||.. .|.| ||...||           .  . ..|..||.||.|||...        |.|||||. |||.|....           
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNA

---AVIADFGLSGHVEN----------------------QMNESVGTPHYSAPEMLVHT----------------AYTSKVDVYSYAIVVWEMLTGEVPF
   . |.|||||  ...                      . .  .||| . |||.|  .                 |. |.||||..|| ||.||...|.
DWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPY

NDKVLDKIY---------EHVVTFGWRLPIP------------DSASPGLVKLITTCWSKDPTERPEFHQIVKQF
 |   . ..         . |.  | |.|||            ... |.. ||.. ||. ||..|| | .|.|..
YDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 91127.m00275.AA Pkinase 101-347 28 3.2e-71 247.73 Pfam 7-293 (293) Show / Hide 
Range on Protein: 101-347
Range on HMM: 7-293/293
Sequence Identity: 28% (83 aa)

LGAGGFGTVSKATLKRTSEFVAVKKIRYDKLSPKAWQSIWD--EITLMKKLHHPCILELVGAQI-HEPYCIITRFCSGR----SLFDRLHRQKTNQLPAL
.|.|.||.| |.. | |.. ||||.|.... ... .|. .   || .||.|.||.|..| ..   .  ..... .| |     .|||...... . .  .
IGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFY-F

QPTELTKIAYQIALGMEYLHAQKIVHRDLKTLNILLDDKNNA----VIADFGLSG---HVENQMNESVGTPHYSAPEMLV-HTAYTSKVDVYSYAIVVWE
.. |. ...|||. |.||.|...|.|||||  |||.|....      |.||||.    .  |.|.  .|||.| ||| .  .. |..|||..|. ....|
SEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYE

MLTGEVPFNDK------VLDKIYEHVVTFGWRLPIPDSAS-------------------PGLVKLITTCWSKDPTERPEFHQIVKQ--F
||.|. || ..        ..... .    .. ..| . |                   . . ..|. |. |||..|| ..||..   |
MLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 91127.m00275.AA MLK 95-347 30 5.5e-71 242.13 In-house 1-291 (291) Show / Hide 
Range on Protein: 95-347
Range on HMM: 1-291/291
Sequence Identity: 30% (88 aa)

NPNDNHLGAGGFGTVSKATLKRTS---EFVAVKKIRYDKLSPKAW-----QSIWDEITLMKKLHHPC----ILELVGAQIHE-P-YCIITRFCSGRSLFD
  .  ..|.|.|| | |.. . .      ||||..| ..   |.      . .  |. . ..| ||     | ...|. . . . .||.. .|.| ||..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

RLHRQKTNQLPA---------LQPTELTKIAYQIALGMEYLHAQK---IVHRDLKTLNILLDD------KNNAVIADFGLSGHVENQ---MNESVGTPHY
 || ....  .|           .  . ..|.|.| ||.|||...   |.|||||  |||.|.      . ...|.|||.|  . .    |    ||. .
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAW

SAPEML---VHTAYTSKVDVYSYAIVVWEMLTGEVPFN--DKVLDKIYEHVVTFGWRLPIPDSASPGLVKLITTCWSKDPTERPEFHQIVKQF
 |||..    .. |. |.||.|...| |||||.|||.   .. .  ... |.  | |.||| ...... ||.. ||. || .|| | |||...
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWW-VAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 91127.m00275.AA Dicty4 98-349 31 1.2e-67 224.77 In-house 4-277 (277) Show / Hide 
Range on Protein: 98-349
Range on HMM: 4-277/277
Sequence Identity: 31% (87 aa)

DNHLGAGGFGTVSKATLKRTSEFVAVKKI--RYDKLSPKAWQSIWDEITLMKKLHHPCILELVGAQI---HEP--YCIITRFCSGRSLFDRLHRQKTNQL
.. .| |.||.| |.| . .   |||||   . .... .  ..   |...|.|. || |. . || .    .|   || | ...  .|.  || .   | 
EQRIGKGSFGEVYKGTWRGKE--VAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQ

PALQPT--ELTK---IAYQIALGMEYLHA--QKIVHRDLKTLNILLDDKNNAVIADFGLSG---HVE--NQ-MNESVGTPHYSAPEMLVHTAYTSKVDVY
.  ..     ..   .|  .|.|| .||.    |.|||||. |.| |. ... ..|||||     .|  .. .   .||| . |||...| .|..|.|||
QSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADVY

SYAIVVWEMLTGEVPFN--DKVLDKIYEHVVTFGWRLPIPDSASPGLVKLITTCWSKDPTERPEFHQIVKQ--FED
|..|| ||.||.. |..   . ...... |.  . |.||||. .| . .||..||..||. || | .|...   | 
SFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase 91127.m00275.AA S_TKc 95-352 28 4.6e-67 230.02 SMART 1-231 (231) Show / Hide 
Range on Protein: 95-352
Range on HMM: 1-231/231
Sequence Identity: 28% (77 aa)

NPNDNHLGAGGFGTVSKATLKRTSEFVAVKKIRYDKLSPKAWQSIWDEITLMKKLHHPCILELVGAQIHEPYCIITRFCSG--RSLFDRLHRQKTNQLP-
    ...| |.||.| |.. |.| . ||.|.|.         ..|. || ..|| ||| |  | ..  .. ..... .|.|   .|||........ |. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

ALQPTELTKIAYQIALGMEYLHAQKIVHRDLKTLNILLDDKNNAVIADFGLSGHVENQMNESVGTPHYSAPEMLVHTAYTS-KVDVYSYAIVVWEMLTGE
 . . .  ...|||....||.| ..|.|||||  |||||.  .  |.||||. ..    .  .|||.| |||.|    |.  |.|..|  ....|||.|.
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGY

VPFNDKVLDKIYEHVVTFGWRLPIPDSASPGLVKLITTCWSKDPTERPEFHQIVK----QFEDGLI
 ||    .........            || .  .|  |. |||..||   .. .       .  .
PPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 91127.m00275.AA TKL-Unique 99-347 31 8.2e-65 221.64 In-house 3-290 (290) Show / Hide 
Range on Protein: 99-347
Range on HMM: 3-290/290
Sequence Identity: 31% (91 aa)

NHLGAGGFGTVSKATLKRTSEFVAVKKIRY-DKLSPKAWQSIWDEITLMKKLH-HPCILELVGAQI----HEP-YCIITRFCSGRSLFDRLHR-----QK
| .|.||.|.| |.. ....  ||.|..    ..|..  |   .|...||||| || |. ..|. .    ..| .||.. .|.| || | ||.       
NKIGEGGYGQVYKGKWRGYP--VAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

TNQLPALQPTELTKIAYQIALGMEYLHAQK--IVHRDLKTLNILLDDK-----NNAVIADFGLSGHVENQMNESVG------------TPHYSAPEMLVH
 |.   | .    |.| .||.||.|||  .  | |||||..|.|.| .     .|. |.|||||    . ......            .. ..|||.|  
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--TAYTSKVDVYSYAIVVWEMLTGEV------PFNDKVLDKIYEHVVT--FGWRLPIPDSASPGLVKLITTCWSKDPTERPEFHQIVKQF
  . |. |.||||..||.||..|...      |. .   ....| | .   . |.|||..  . . .||. ||  ||..|| | .|..  
NFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 91127.m00275.AA Pkinase_Tyr 101-347 30 1.4e-62 212.53 Pfam 7-270 (270) Show / Hide 
Range on Protein: 101-347
Range on HMM: 7-270/270
Sequence Identity: 30% (82 aa)

LGAGGFGTVSKATLK----RTSEFVAVKKIRYDKLSPKA--WQSIWDEITLMKKL-HHPCILELVGAQI--HEP--YCIITRFCSGRSLFDRLHRQKTNQ
||.| ||.| |.|.|     |   ||||..  .. ....  ...   |. .||.| ||| |. |.|. .   ||  ..|.. .. . .| | |.... ..
LGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHR-ED

LPALQPTELTKIAYQIALGMEYLHAQKIVHRDLKTLNILLDDKNNAVIADFGLSGHV-----E-NQMNESVGTPHYSAPEMLVHTAYTSKVDVYSYAIVV
 ..| . .| ....||| |||||......|||| . |.|....| . |.||||.  .        .  ..       ||| . .  .|.| ||.|. .. 
KQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLM

WEMLT-GEVP-FNDKVLDKIYEHVVTFGWRLPIPDSASPGLVKLITTCWSKDPTERPEFHQIVKQF
||..| || | . .     .||..   | |.|.|. ... . .|.. || .|| .|| | .|. |.
WEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 91127.m00275.AA TyrKc 97-347 27 1.5e-62 215.08 SMART 3-280 (280) Show / Hide 
Range on Protein: 97-347
Range on HMM: 3-280/280
Sequence Identity: 27% (81 aa)

NDNHLGAGGFGTVSKATLKRTSEFVAVKKIRYDKLSPKAWQSIWDEITLMKKL--HHPCILELVGAQIH--------EPYCIITRFCSGRSLFDRLHRQK
 .  || | ||.| |.|.|   . ||||... |.      . . .|. .|.||  |||.|. |.|. ..        ||..|.. .... .| |.|.. .
LGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

TNQLPALQPTELTKIAYQIALGMEYLHAQKIVHRDLKTLNILLDDKNNAVIADFGLSGHVENQ--------MNES---VGTP-----HYSAPEMLVHTAY
 .    |.. .| ....||| |||||| ....|||| . |.|..... . |.|||||  ...         .  .    |.         ||| . .  .
PK----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

TSKVDVYSYAIVVWEMLT-GEVPFND-----KVLDKIYEHVVTFGWRLPIPDS--------ASPGLVKLITTCWSKDPTERPEFHQIVKQF
|.| ||.|. .. ||..| |. |  .     .  . ..|.| . . |.|.|..        ... . .....||  || .|| | .|...|
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGY-RMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 91127.m00275.AA LRRK 85-349 27 1.2e-57 197.79 In-house 1-351 (351) Show / Hide 
Range on Protein: 85-349
Range on HMM: 1-351/351
Sequence Identity: 27% (98 aa)

LNESDLDYTLNPNDNHLGAGGFG-TVSKATLK--------------------------RTSEFVAVKKIRYD----------------------------
| .  .          .| |||| .| .|...                          . .. ||.||.  |                            
LKIEEQ----------IGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDM

----KLSPKAWQSIWDEITLMKKLHHPCILELVGAQIHEPYCIITRFCSGRSLFDRLHRQKTNQL----PALQPTELTKIAYQIALGMEYLHAQK--IVH
      ...| ..   |...| .|.||.|. |.|  || |.|... . .  .| ..||  | ...    . . .. . |||.||| |||||| ..  |.|
DQNHEDCCRAFREFRHEVWIMSHLNHPNIVSLKGFCIH-PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIH

RDLKTLNILL--DDKN----------NAVIADFGLSG---HVENQ-MNESVGTPHYSAPEMLVHT---AYTSKVDVYSYAIVVWEMLTGE-VPFNDKV--
||||. ||||   . |          .| |||||.|.    . .   . .||.| . ||| .  .    || |||.||.... || ||..  || . .  
RDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFF

----LDKIYEHVVTFGWRLPIPDS-ASP-----GLVKLITTCWSKDPTERPEFHQIVKQFED
    .  . |  .. | | .|| .   |      . .||. ||. ||..|| | ||||. ..
DHMQWMEQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 91127.m00275.AA TK 101-347 16 4.4e-56 186.14 In-house 7-486 (486) Show / Hide 
Range on Protein: 101-347
Range on HMM: 7-486/486
Sequence Identity: 16% (81 aa)

LGAGGFG---TVSKATLKRTS-------------------------EFVAVKKIR-YDKLSPKAWQS--------------IWDEITLMK--KLHHPCIL
||.| ||   .| |..... .                         . |||| ..  |  |... .                . |. .|.  ..||| |.
LGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIV

ELVGAQIHE-------------PYCIITRFCSGRS----LFDRLH--RQKTNQLPA--------------------------------------------
 |.|.  ..             |..|.. .... .    | | |.  | |... .                                             
RLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIK

-------------------------LQPTELTKIAYQIALGMEYLHAQ------KIVHRDLKTLNILLDDKNN-----------AVIADFGLSG-----H
                         | . .|  ...||| ||||||..      ..||||| . |.|....|.           . |||||||      .
DHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVL

VENQMNESVGTPHY--------------------------------SAPEMLVHTA---------YTSKVDVYSYAIVVWEMLT-GEVPFN---------
     ...  . .                                  ||| | .           .|.| ||.|. ...||..| |..|.          
ARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVW

--DKVLDKIYEHVVTF-------------GWRLPIPDSASP-------------GLVKL-ITTCWSKDPTERPEFHQIVKQF
  . ... ..|....              . |.| |. ...              .. . .. ||..|| .|| | |...|.
KDG-DNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 91127.m00275.AA STE 95-342 23 5.9e-55 188.88 In-house 1-350 (359) Show / Hide 
Range on Protein: 95-342
Range on HMM: 1-350/359
Sequence Identity: 23% (82 aa)

NPNDNHLGAGGFGTVSKATLK------RTSEF---------VAVKKIRYDKLSP---------------KAWQSIWDEITLMKKLH--HPCILELVGAQI
  .   .| |.|||| ||  .      .| |          .|.|...... ..               . .|.|  || .|||..  || | .  |. .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

HEP--------YCIITRFCSGRSLFDRLH-RQKTNQ-LPALQ-------PTELTKIAYQIALG-MEYLHAQKIVHRDLKTLNILLDDKNNAVIADFGLSG
.|          .|.  ...| || | .. . .... |.  .        ... .|..||  | ..||| ..|.|||.|  ||||     . ..|||..|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

HVEN-------------------QMNESVGTPHYSAPEMLVH------TAYTSKVDVYSYAIVVWEMLTGEVPFNDKVLDKIYEHVVTF-----------
 ...                   . |  |||| . |||..          |. |.|..|  ....||.||..|. |    . . .  .            
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---GWRLPIPD-------------------SASPGLVKLITTCWSKDPTERPEFHQ
   |   |.||                   . || .   |  |  ||| .||  .|
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ
Kinase 91127.m00275.AA Dicty4-Unclassified 98-347 33 4.3e-51 173.23 In-house 4-263 (263) Show / Hide 
Range on Protein: 98-347
Range on HMM: 4-263/263
Sequence Identity: 33% (87 aa)

DNHLGAGGFGTVSKATLKRTSEFVAVKKIRYDKLSPK--AWQSIWDEITLMKKLHHPCILELVGAQIHEP------YCIITRFCSGRSLFDRLH--RQKT
|  .| | |  | |   |     |||||.   | .      |    |. ..  . ||  . . |. |  |      .||.. |     ||   |      
DQFIGKGHFSKVHKGNWKGKD--VAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCI-NPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQ

NQLPALQPTELTKIAYQIALGMEYLHAQKIVHRDLKTLNILLDDKNNAVIADFGLSGHVENQMN-ESVG-TPHYSAPEMLVHTAYTSKVDVYSYAIVVWE
.|   |  |   |.|  || || .||   ..|||.|  |||.|  .|. |||||.|  ...  |   .. ||   .|| | | .|..| ||||||.. .|
QQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMMLYE

MLTGEVPFNDKV-LDKIYEHVVTFGWRLPIPDSASPGLVKLITTCWSKDPTERPEFHQIVKQF
..||. |. .      .   |   . |  |||.  . . |||  ||. ||  || . ||..  
LATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase 91127.m00275.AA ULK 95-305 29 2.2e-48 167.01 In-house 1-272 (329) Show / Hide 
Range on Protein: 95-305
Range on HMM: 1-272/329
Sequence Identity: 29% (79 aa)

NPNDNHLGAGGFGTVSKATLKRT----SEFVAVKKIRYDKLSPKA--------WQSIWDEITLMKKLH----HPC----ILELVGAQIHE---PYCIITR
   .. || | ||.| |.. |.|     | ||.|.|  .|.. |         ||..  || .||||.    |..    | .|   .       . ||. 
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FCSGRSLFDRLHRQKTNQLPA-----LQPTELTKIAYQIALGMEYLHAQKIVHRDLKTLNILLDDKNNAV------------IADFGLSGHVENQ-----
.| |  |.. ....|.  ..      |   |  .. .||. |. .|| ..|.|||.|  |||.....               |||||.. ||.|      
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-MNESV------GTPHYSAPEMLV----HTAYT-SKVDVYSYAIVVWEMLTGEVP----FNDKVLDKIYEHV
 |   |      ||| | ||. |     .  |. .|.|..|  ..  |||.|..|    ||| .| .|.. .
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLI
Kinase 91127.m00275.AA ULK 95-305 28 4.4e-48 166.07 In-house 1-267 (324) Show / Hide 
Range on Protein: 95-305
Range on HMM: 1-267/324
Sequence Identity: 28% (78 aa)

NPNDNHLGAGGFG-TVSKATLKRT---SEFVAVKKIRYDKLSPKA--------WQSIWDEITLMKKLH---HPC--ILELVGAQIHE---PYCIITRFCS
   .. || | || .| |.. |.|    ..||.|.|  .|.. |         ||..  || .||||.   ||   | .|   .       ..||. .| 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GRSLFDRLHRQKTNQLPA-----LQPTELTKIAYQIALGMEYLHAQKIVHRDLKTLNILLDDKNNAV------------IADFGLSGHVEN-QMNESV--
|  |.. ....|.  .       |   |  .. .||. |. .|| ..|.|||.|  |||. ...               |||||.. ||.| .|.. .  
GGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

---------GTPHYSAPEMLV----HTAYT-SKVDVYSYAIVVWEMLTGEVP----FNDKVLDKIYEHV
         ||| | ||. |     .  |. .|.|..|  ..  |||.|..|    ||| .|  |....
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLY-IQKLI