90729.m00103

Species: T.vaginalis
Alias: 90729.m00103, TvagK0313
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
90729.m00103.AA Protein None 963 None Fasta, JSON
90729.m00103.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 90729.m00103.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 90729.m00103.AA TKL 202-447 25 5.2e-88 298.69 In-house 1-364 (364) Show / Hide
Range on Protein: 202-447
Range on HMM: 1-364/364
Sequence Identity: 25% (95 aa)

IGLGGYATVHLAKMRS--------TGEMVAVKELKAVQ-----------------------LNQTRVIYLKREIDALMRLS--HPNVIKLIGVTVTPP--
|| ||...|. .| |         ||. |||| .|  .                        . .. .  ..|  ..| ..  |||.....|.   ||  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------FCIVTTYVPNGC-LIDLINGKSINPRCTPIFRMRIALDTARALEYIHSIG--------LIHRDLKPPNILLDNNDR------------
            .|||. |.|.|. | .|.          .  |.|.|||.||...| || .        .||||||..|||.|.| .            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--AIVCDFGLARIVSSM--MSC--------------------EIGTTQWCAPELLTSGN---------------DYNQSVDVYAYGIMLWELLTQKIPFK
  . .|||||.| .| .  |..                    ..||..|.|||.|   .               .|....|||..||.|||.|| ..|..
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY

GLKCI---------QICECVLKYAERPEIP------------EDCPEMFATVIKRCWAQHPEERPTFQQIREVF
.....         .. . | .  .||.||            .|||. ..  ...||.. ||.||.||.| . .
DYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase 90729.m00103.AA MLK 198-447 31 5.5e-73 248.78 In-house 3-291 (291) Show / Hide
Range on Protein: 198-447
Range on HMM: 3-291/291
Sequence Identity: 31% (90 aa)

IKENIGLGGYATVHLAKMRSTG---EMVAVKELK----AVQLNQTRVIYLKREIDALMRLSHPN----VIKLIGV-TVTPP-FCIVTTYVPNGCLIDLIN
..| || |..  |.....| .      ||||. .    ...   .    ...|.  | .|||||    .|.. || . .|. ||||. |...|.| ....
FHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLH

GKSINPR-----------CTPIFRMRIALDTARALEYIHSIG---LIHRDLKPPNILLDN------NDRAIVCDFGLARIVSSM---MSCEIGTTQWCAP
|.....             .. . |..||. ||...| ||     .||||||..|||.|.      .. . .||||..| ...|   | . .||  | ||
GARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWMAP

ELL--TSGNDYNQSVDVYAYGIMLWELLTQKIPFK-GLKCIQICECVLKYAERPEIPEDCPEMFATVIKRCWAQHPEERPTFQQIREVF
| .    .. |. ..||. .|..|||.|| ..|.| ......|   |    .|| || .||| ..  .|.|| | |..||.|.|| . .
EVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL

Kinase 90729.m00103.AA TKL-Unique 198-447 30 1.8e-71 243.73 In-house 1-290 (290) Show / Hide
Range on Protein: 198-447
Range on HMM: 1-290/290
Sequence Identity: 30% (90 aa)

IKENIGLGGYATVHLAKMRSTGEMVAVKELKAVQLNQTRVIY-LKREIDALMRLS-HPNVIKLIGVTV----TPP-FCIVTTYVPNGCLIDLIN------
. . || |||..|  .| |  |. ||.| ..   .   ...  ...|.  . .|  |||. ...|...    .|| .|||. |.| | | |...      
FWNKIGEGGYGQVYKGKWR--GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

---GKSINPRCTPIFRMRIALDTARALEYIHSIG--LIHRDLKPPNILLDNN-----DRAIVCDFGLARIVSSM--MSCE----------IGTTQWCAPE
    .....  ..  |...|.| |....|.|. .   ||||||..|.|.|||      .. .|||||... |..  |.            .|...| |||
NNNNNNCKL--NMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPE

LLTSG-NDYNQSVDVYAYGIMLWELLTQKI------PFKGLKCIQICECVLK--YAERPEIPEDCPEMFATVIKRCWAQHPEERPTFQQIREVF
.|..  ..|....|||..||.|||..| ||      |..|.  .|.|| | .     ||.||..||. .   |..||.. |..||.|..|..  
VLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL

Kinase 90729.m00103.AA Dicty4 198-449 33 2.6e-64 213.44 In-house 3-277 (277) Show / Hide
Range on Protein: 198-449
Range on HMM: 3-277/277
Sequence Identity: 33% (92 aa)

IKENIGLGGYATVHLAKMRSTGEMVAVKELKAVQLN--QTRVIYLKREIDALMRLSHPNVIKLIGVTV----TP-PFCIVTTYVPNGCLIDLING-----
| . || |....|.... |  |  |||| |.. . |  . .   ...|.. .  ..|||.... |       .|  .|||| |.| | |  |..      
IEQRIGKGSFGEVYKGTWR--GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

-KSINPRCTPIFR-MRIALDTARALEYIHS-I-GLIHRDLKPPNILLDNNDRAIVCDFGLAR-----IVSSM-MSCEIGTTQWCAPELLTSGNDYNQSVD
 .|| .  . | | ||.|.|.|| . . |. .   ||||||. |.| | | |. ||||||..     .  .  ..  .||. | ||| .  .. ||...|
QQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMM-HQPYNEKAD

VYAYGIMLWELLTQKIPFK--GLKCIQICECVLKYAERPEIPEDCPEMFATVIKRCWAQHPEERPTFQQIREV--FER
|| .||.|||.|| ..|.   .    |. . |    .||.|| .||  ... |..||   |. ||.|..| .    | 
VYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH

Kinase 90729.m00103.AA LRRK 196-449 25 6.7e-62 211.95 In-house 1-351 (351) Show / Hide
Range on Protein: 196-449
Range on HMM: 1-351/351
Sequence Identity: 25% (90 aa)

QIIKENIGLGGYA-TVHLAKMRS--------------------------TGEMVAVKELKA-----------------------VQLNQTR--------V
..| | || ||.. .|. ||.|.                           ...||.| ..                        .|..            
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVED-MDQNHEDCCR

IY--LKREIDALMRLSHPNVIKLIGVTVTPPFCIVTTYVPNGCLIDLINGKSINP------RCTPIFRMRIALDTARALEYIHSIG--LIHRDLKPPNIL
..  . .|.  . .| |||...|.|..   |.|.|. |.|.| | ...  |. ..      . .. .. .|||. |...|| ||    .||||||.||||
AFREFRHEVWIMSHLNHPNIVSLKGFCIH-PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNIL

L---DNND---------RAIVCDFGLAR----IVSSMMSCEIGTTQWCAPELLTSG--NDYNQSVDVYAYGIMLWELLTQK-IPFKGLK-------CIQI
|   ..|.          | ..|||. |    . ..  .   |. .|.||| .  .    |.. ||.|..|. |||||| . .|| ...        .||
LWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQI

CECVLKYAERPEIPED-CPE-----MFATVIKRCWAQHPEERPTFQQIREVFER
 .....   || ||.. ||.     |. . |. ||...|..||.|.|| .. . 
EDKIIE-GLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ

Kinase 90729.m00103.AA S_TKc 196-447 28 1e-58 202.33 SMART 1-231 (231) Show / Hide
Range on Protein: 196-447
Range on HMM: 1-231/231
Sequence Identity: 28% (75 aa)

QIIKENIGLGGYATVHLAKMRSTGEMVAVKELKAVQLNQTRVIYLKREIDALMRLSHPNVIKLIGVTVTPPFCIVTTYVPN--GCLIDLINGKSINPRC-
  | . || |....|.... ..||. ||.|..|         . ..|||. |..  |||..||..| ..  ...|. |...  | | |.|  .  .... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

--TPIFRMRIALDTARALEYIHSIGLIHRDLKPPNILLDNNDRAIVCDFGLARIVSSMMSCEIGTTQWCAPELLTSGNDYNQ-SVDVYAYGIMLWELLTQ
  ..    ...  ...||||.|| | ||||||| |||||.  .  .|||||||..    .  .||  ..|||.|     |.  ..|... |..|.|.|. 
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCG

KIPFKGLKCIQICECVLKYAERPEIPEDCPEMFATVIKRCWAQHPEERPTFQQIRE---------VF
. ||      .. . ..            .. .   |..|.   ||.|||  .. .          |
YPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 90729.m00103.AA Dicty4-Unclassified 196-447 31 3.6e-54 183.91 In-house 2-263 (263) Show / Hide
Range on Protein: 196-447
Range on HMM: 2-263/263
Sequence Identity: 31% (84 aa)

QIIKENIGLGGYATVHLAKMRSTGEMVAVKELKAVQLNQTR---VIYLKREIDALMRLSHPNVIKLIGVTVTP-----PFCIVTTYVPNGCLIDLIN---
|| .. || |  . ||  |    |  |||| .   .  . |   .   |.|.. |  ..||| .|. |  . |      .|||.   . | |. .|.   
QIDQF-IGKGHFSKVH--KGNWKGKDVAVKKFNENK-FKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKP

---GKSINPRCTPIFRMRIALDTARALEYIHSIGLIHRDLKPPNILLDNNDRAIVCDFGLARIVSSMMS-CEIG-TTQWCAPELLTSGNDYNQSVDVYAY
    ..|    | |  ...|.| |. . . |.  .||||.|  |||.| .  . . |||..| ..       |. |  | .|| |  .  |||  ||| |
SEQQQPIKLDDTLI--IKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLM-HESYNQKSDVYSY

GIMLWELLTQKIPFKGLK-CIQICECVLKYAERPEIPEDCPEMFATVIKRCWAQHPEERPTFQQIREVF
..||.||.|   |. .    . .   |     ||.||. |.  .   || ||   |  |||. || .  
AMMLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL

Kinase 90729.m00103.AA Dicty5 241-451 35 2.7e-53 181.79 In-house 44-260 (260) Show / Hide
Range on Protein: 241-451
Range on HMM: 44-260/260
Sequence Identity: 35% (78 aa)

KREIDALMRLS---HPNVIKLIGVTVTPPFC--IVTTYVPNGCLIDLINGKSI----NPRCTPIFRMRIALDTARALEYIHSIGLIHRDLKPPNILLDNN
.||. ..| ..   |||.|.  |          .|| |. || | .. | .      ..      .. .|.| |......||.. ||||||  |.|.  |
YREV-TIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQPIAY--FQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITEN

DRAIVCDFGLARIVSS--MMSCEIGTTQWCAPELLTSGNDYNQSVDVYAYGIMLWELLTQKIPFKGLKCIQICECVLKYAERPEIPEDCPEMFATVIKRC
  . . |||  | |     |  ..||  | |.|| . |. | | .|||..|| |||..|.| |.. .  . |   | |  |||.|| |||  .. .|| |
WKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFN-GQPYHQKCDVYSFGIVLWEMFTRKEPYDNINNWNIPVMVMK-GERPTIPKDCPTEISNLIKKC

WAQHPEERPTFQQIREVFERGD
| | |  ||.|  | ..||.  
WQQKPHNRPSFKEICKYFESII

Kinase 90729.m00103.AA TyrKc 196-447 25 5.5e-53 183.26 SMART 1-280 (280) Show / Hide
Range on Protein: 196-447
Range on HMM: 1-280/280
Sequence Identity: 25% (74 aa)

QIIKENIGLGGYATVHLAKMRSTGEMVAVKELKAVQLNQTRVIYLKREIDALMRL--SHPNVIKLIGVTVT--------PPFCIVTTYVPNGCLIDLING
   .. .| | . .|......   ..|||| ||.       .  . ||.  ...|  .|||...|.|| ..        .| .||. |.|.|.| | .  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KSINPRCTPIFRMRIALDTARALEYIHSIGLIHRDLKPPNILLDNNDRAIVCDFGLARIVSSM----------MS----CEI--GTTQWCAPELLTSGND
.  .   ..     .... |.  ||.|| ..|||||   |.|...| .. ..||||.| . .           ..    ..       |.||| .   . 
HRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGK

YNQSVDVYAYGIMLWELLTQ-KIPFKG-----LKCIQICECVLKYAERPEIPED--------CPEMFATVIKRCWAQHPEERPTFQQIREVF
..   ||...|...||..|  . |  |     .. ... |.| .  .|...|..        ||.   ...|.||.  ||.||||..|.| |
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQ-GYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase 90729.m00103.AA Pkinase 196-447 28 1.8e-52 185.41 Pfam 1-293 (293) Show / Hide
Range on Protein: 196-447
Range on HMM: 1-293/293
Sequence Identity: 28% (85 aa)

QIIKENIGLGGYATVHLAKMRSTGEMVAVKELKAVQLNQTRVIYLKR--EIDALMRLSHPNVIKLIGVTVTPP-FCIVTTYVPNG----CLIDLIN---G
  |.. || |....| ... ..||..||||..| .  .    ... |  ||  . ||.|||...|...  ...  ..|. |...|     | |.|    .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KSINPRCTPIFRMRIALDTARALEYIHSIGLIHRDLKPPNILLDNNDRA----IVCDFGLA----RIVSSMMSCEIGTTQWCAPELLTSGNDYNQSVDVY
...    ..    .... ..|.|||.|| | ||||||| |||.|||.       .||||||       .| |.   ||  ..|||.. .|..| ..||..
GCFY--FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

AYGIMLWELLTQKIPFKGL------KCIQICECVLKYAERPEIPEDCP-------------------EMFATVIKRCWAQHPEERPTFQQIREV--F
..|..|.|.|. . ||.|         .|. . ...   . ..|..|.                   | .  .||.|... |..|||..|| .   |
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 90729.m00103.AA TK 196-447 15 2.5e-52 173.35 In-house 1-486 (486) Show / Hide
Range on Protein: 196-447
Range on HMM: 1-486/486
Sequence Identity: 15% (76 aa)

QIIKENIGLGGYA---TVHLAKMRSTG-------------------------EMVAVKELKAV-QLNQTRVIY--------------LKREIDALM--RL
 .. . .| | .    .|.....|. .                         . |||| ||.    .|.. .               . .|.  ..   .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

SHPNVIKLIGVTVT-------------PPFCIVTTYVPNGC----LIDLINGKSINPR------------------------------------------
 |||...|.|| .              .|..||. |.|.|.    | |    .. . .                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------CTPIFRMRIALDTARALEYIHSI------GLIHRDLKPPNILLDNNDR-----------AIVCDFG---
                                |.  .. .... |...||.||       ...||||   |.|...|..           . ..|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LARIV---SSMMSCEIGTTQ--------------------------WCAPELLTSG--------NDYNQSVDVYAYGIMLWELLT--QKIPFKGL
     ||| .   .   . . ..|                           |.||| |...        . .    ||...|...||..|  |. .  |.
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

K---------CIQICECVLK-------------YAERPEIPEDCP--------------EMFATVIKRCWAQHPEERPTFQQIREVF
          . ...|.. .             |  |.. |..||              |... ....||.  ||.||||.|..| .
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase 90729.m00103.AA Pkinase_Tyr 197-447 28 1.3e-50 172.08 Pfam 2-270 (270) Show / Hide
Range on Protein: 197-447
Range on HMM: 2-270/270
Sequence Identity: 28% (77 aa)

IIKENIGLGGYATVHLAKMR----STGEMVAVKELKAVQLNQTR--VIYLKREIDALMRL-SHPNVIKLIGVTV--TPP--FCIVTTYVPNGCLIDLING
.. . .| | . .|......    .|.  |||| ||  .  .       . ||.  .. | .|||...|.|| .    |   .||. |.|.|.| |    
TFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

K-SINPRCTPIFRMRIALDTARALEYIHSIGLIHRDLKPPNILLDNNDRAIVCDFGLARIV-----S-SMMSCEIGTTQWCAPELLTSGNDYNQSVDVYA
. . ... |.     .... |...|| .|...|||||   |.|...|  . .||||||| .        . .       |.||| .  |  ..   ||..
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSDVWS

YGIMLWELLT-QKIP-FKGLKCIQICECVLKYAERPEIPEDCPEMFATVIKRCWAQHPEERPTFQQIREVF
.|. .||..|  ..| ..|..  ...| . .  .| ..||.||.   ...|.||.. ||.||||..|.| .
FGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase 90729.m00103.AA RIPK 202-447 28 1.6e-49 166.88 In-house 1-290 (290) Show / Hide
Range on Protein: 202-447
Range on HMM: 1-290/290
Sequence Identity: 28% (84 aa)

IGLGGYATVHLAKMRSTGEMVAVKELKAVQ----LNQTRVIYLKREIDALMRLSHPNVIKLIGVTVTP------P-FCIVTTYVPNGCLIDLINGKSI--
.| ||  .| .|  |. |..||.|  .  .    ...  . |.|.|  .. .| . .. .. |..  .        . ||. | .|| | ..   |.   
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

-NPRCTPIFRMRIALDTARALEYIHSIG--LIHRDLKPPNILLDNNDRAIVCDFGLA--RIVSSMMS--C------------EIGTTQWCAPELLTSGND
  |.. |  | |.   ....  | ||..  .||||||| |||.|||  . . |||||  .  |. ..  |            . ||    .||..  .| 
HHPDPWPL-RCRMIHEISCGMCYLHSMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNK

YN-----QSVDVYAYGIMLWELLTQKIPFKGLKCIQICECVLKYAERP---EIPEDCPEM-----FATVIKRCWAQHPEERPTFQQIREVF
          ||| ..| .||.|||| |. . ||... . ..|   ||   ..|| .||         ...|||.| |..||.|| ..| .
KPIKVVTPKYDVYSFAIVMWEVLTQKHPYEDRKCMMMIMMCCKQGHRPCLQPVPEYWPEPPHCEQMIELMQRCWQQDPNDRPCFQECEEWT

Kinase 90729.m00103.AA TKL-ciliate2 197-448 34 1.7e-49 163.08 In-house 2-273 (273) Show / Hide
Range on Protein: 197-448
Range on HMM: 2-273/273
Sequence Identity: 34% (96 aa)

IIKENIGLGGYATVHLAKMRSTGEMVAVKELKAVQLNQTRVIYLKREIDALMRLSHPNVIKLIGV-TVTPPFCIVTTYVPNGCLIDLINGKSINPRCTPI
 |.. |  |||  .  || | .  .||||  | .  || ..     | .|.  | |||..  .|  |  | |||.  |   | |  |.  ...  | |  
EIQNKITEGGYGIIYKAKWREI--VVAVKKFKMDHDNQQQIRDFVNECHAMEALRHPNIVMFLGACTKIPNFCIIMEYCQRGSLWSLLQNQDV--RLTWE

FRMRIALDTARALEYIHSIG--LIHRDLK--------------------PPNILLDNNDRAIVCDFGLARIV--SSMMSCEIGTTQWCAPELLTSGNDYN
 | ||||| ||   |.||    .||||||                      |.|.| | |  . |||  |.      |   ||| || ||| . . . | 
DRRRIALDIARGVHYLHSSNPPIIHRDLKRQIKHKEKNLINIITLIKINSLNVLVDDNFRCKLTDFGWTRVKPQDNYMTNKIGTYQWMAPEVIKA-FYYT

QSVDVYAYGIMLWELLTQKIPFKGLKCIQICECVLKYAERPEIPEDCPEMFATVIKRCWAQHPEERPTFQQIREVFE
   ||..|.|.|||.     |... |   . | |..   || || .||  || ...||| .  . ||.|..|   .|
EKADVFSYSIILWEIASREPPYRNKKGDVVAEKVMCNNLRPTIPKNCPPQFADLMQRCWDNNQNLRPSFNEIIKELE