Gene 81732.m00007 (T.vaginalis)

81732.m00007

Species: T.vaginalis
Alias: TvagK0146, 81732.m00007
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
81732.m00007.AA Protein None 269 None Fasta, JSON
81732.m00007.kin_dom Protein Kinase Domain None 206 None Fasta, JSON

Protein domain

Protein domains of 81732.m00007.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 81732.m00007.AA CAMK 4-209 19 1.6e-50 160.66 In-house 79-425 (425) Show / Hide 
Range on Protein: 4-209
Range on HMM: 79-425/425
Sequence Identity: 19% (67 aa)

QSEIECLKA-------IDDPRIVRLYQVYNFGGF-------------------IYLLM---ELCKND------LDKIYKHKK--------------MTTP
..|||..|        .| | |..||.||  . .                   .|. |   |.| .       .|.| .|..                | 
RREIEIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTE

EELFKVVHDTVLAVKACHDRHIAHSDIKPANFLIDQYD-----------------RIKISDFGLSSCYEN------------------------ECKCCL
.|  ....  . ||. ||...|.| |.|| | |.|. .                  |||.|||..  ..                           |.  
REARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKT

FKGTKLFMA-PEIFSK-------------TDYDPFSADIWSLGVTIYYIATHHYPFVDKDLDKIPD-------------LIIKGEYQ-DFRIKDP-----
| ||  .|| ||....              .|.....|.||.||  |   . ..|| ... . |..              |.||.|. .    .|     
FCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNY

------------------DLREVVRCCLTKDVSMHCTVNELLELPYF
                  . .  .|..|..| .   |. . |. | .
GPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 81732.m00007.AA Pkinase 5-209 26 3.9e-44 157.14 Pfam 49-293 (293) Show / Hide 
Range on Protein: 5-209
Range on HMM: 49-293/293
Sequence Identity: 26% (65 aa)

SEIECLKAIDDPRIVRLYQVYNFGGFIYLLMELCKN-----DLD-KIY--KHKKM-TTPEELFKVVHDTVLAVKACHDRHIAHSDIKPANFLIDQYDRI-
|||. .| .. | ||||| ..  .. ||. ||.| .     ||   |   .|...  ...|. ...  .. ... ||.. | | |.||.|.|||. . | 
SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHID

---KISDFGLSSC--YENECKCCLFKGTKLFMAPEIFSKTDYDPFSADIWSLGVTIYYIATHHYPFVDK------DLDKIPDLIIKGEYQDFRIKD----
   ||.||||. .  | |   .  | ||  .||||.  .  |.. ..|.||.|...|. .. . || ..      | ... ..| ....   . ..    
ACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSIS

-----------------PDLREVVRCCLTKDVSMHCTVNELLELPYF
                 .........||.|| .  .|  ..|. |.|
YFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 81732.m00007.AA CAMKL 4-209 29 1.6e-39 123.68 In-house 60-297 (297) Show / Hide 
Range on Protein: 4-209
Range on HMM: 60-297/297
Sequence Identity: 29% (71 aa)

QSEIECLKAID---DPRIVRLYQVYNFGGF------IYLLMELCKND----LDKIYKH----KKMTTPEELFKVVHDTVLAVKACHDRHIAHSDIKPANF
. ||...| ..    | |..||.|.    .      ||| ||.| .     .|.| ||    ..| ...|  .     | ||. ||...|.| |||| | 
RREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRM-PEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENI

LIDQYD--RIKISDFGLSSCYEN-----ECKCCLFKGTKLFMAPEIFSK--TDYDPFSADIWSLGVTIYYIATHHYPFVDKDL------DKIPDLIIKGE
|.|. .   |||.|||.|  |..     . |.  | |.  .||||||..  ..|| . .||||.||. | . . ..|| | ..      ..   ..|.. 
LLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG

YQDFRIK---DPDLREVVRCCLTKDVSMHCTVNELLELPYF
   ..|    . |.|   |  |... .   |. .... | .
-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 81732.m00007.AA MARK 65-173 44 9.3e-35 111.16 In-house 114-226 (262) Show / Hide 
Range on Protein: 65-173
Range on HMM: 114-226/262
Sequence Identity: 44% (50 aa)

VLAVKACHDRHIAHSDIKPANFLIDQYD--RIKISDFGLSSCYENECKCCLFKGTKLFMAPEIFSKTDYDPFSADIWSLGVTIYYIATHHYPFV--DKDL
| ||. ||...|.| |||| | |||.     |||.|||.| | ....|   | ||. .||||||.| .|| . .|||||||  |.. . ..||   ..|.
VSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDY

DKIPDLIIKGEYQ
 ..   | .|.|.
KELYKKILRGKYD
Kinase 81732.m00007.AA Ciliate-E2-Unclassified 1-209 21 1e-34 117.87 In-house 50-352 (352) Show / Hide 
Range on Protein: 1-209
Range on HMM: 50-352/352
Sequence Identity: 21% (65 aa)

MFSQSEIECLK----------------AIDDPRIVRLYQVYNFGGFIYLLMELC------------------KNDLDKIYKHKKMTTPEELF-----KVV
|... |....|                 ...| ||... . .    ||. ||.|                  .|||..  |..|. | ..       .  
MNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYF

HDTVLAVKACHDRH-IAHSDIKPANFLIDQYD---RIKISDFGLSSCYEN----------------ECKCCLFKGTKLFM----APEIFSKTDYDP---F
   ... . .|  . | | |||| | |.|.     .|||.|||.|. |..                ..... | ||  .|    |||.. .  ||    .
AQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAY

SADIWSLGVTIYYIATHHYPFVDKDLDK----------------IPDLIIKGEYQDFR--------IKDPDLREVVR----CCLTKDVSMHCTVNELLEL
..||||||| .|.. .  ||| |.. ..                . . |.....| .         . .|   . ..    ..| |. .   | ...|. 
KCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNH

PYF
|.|
PWF
Kinase 81732.m00007.AA S_TKc 2-209 24 2.4e-33 118.03 SMART 1-231 (231) Show / Hide 
Range on Protein: 2-209
Range on HMM: 1-231/231
Sequence Identity: 24% (62 aa)

FS----------------------------------QSEIECLKAIDDPRIVRLYQVYNFGGFIYLLMELCKN---DLDKIYKHKKM------TTPEELF
.                                   ..||..||  . | ||.|| |.   ...|. ||.| .   || .. |...        .. .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HAR

KVVHDTVLAVKACHDRHIAHSDIKPANFLIDQYDRIKISDFGLSSCYENECKCCLFKGTKLFMAPEIFSKTDYDPFSADIWSLGVTIYYIATHHYPFVDK
.... ...|.. ||...| | |.||.| |.|.  .|||.||||.  .        | ||  .||||..    |.....|.||.|...|  ..   ||   
FYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--

DLDKIPDLIIKGEYQDFRIKDPDLREVVRCCLTKDVSMHCTVNELLE-------LPYF
..... ..|           .|.... .| ||.|| .   |. |.|.        |.|
QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 81732.m00007.AA Ciliate-E2 1-209 19 2.4e-30 101.36 In-house 54-365 (365) Show / Hide 
Range on Protein: 1-209
Range on HMM: 54-365/365
Sequence Identity: 19% (66 aa)

MFSQSEIECLKAIDDPR-----------------------IVRLYQVYN--FGGFIYLLMELCKND--LDKIYKHKKMTTPE-------ELFKVV----H
......|| .| ...                         |...| ..       ||| ||.|.    .| |...||  . |        ....     .
IMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQ

DTV--------------LAVKACHDRH-IAHSDIKPANFLIDQYDRIKISDFGLSSCYENE---------CKCCLFKG----------------------
 .               ||.. .| .. | | |||| | |.     |||.|||||  | ..         || ..| .                      
ILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTI

--TKLFMAPEIFSKTDYDP--------FSADIWSLGVTIYYIATHHYPFVDKDLDKIPDLIIKGEYQDFRIKDPDLR-----------------------
  |  .|||||... .||         ...|||||||..|.  .  .||                .|    .. |..                       
CGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF----------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQ

---EVVRC----CLTKDVSMHCT-VNELLELPYF
      .     .| || .   |  ...|. |.|
ECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 81732.m00007.AA STE 4-209 23 7e-29 99.17 In-house 76-359 (359) Show / Hide 
Range on Protein: 4-209
Range on HMM: 76-359/359
Sequence Identity: 23% (67 aa)

QSEIECLKAID--DPRIVRLYQVYNFGG-------FIYLLMELCK-NDLDKIYKHKKMT-TP------------EELF-KVVHDTVLA-VKACHDRHIAH
. ||. .|  .   | ||. |  |  .|        ... ||..    ||.|.|||...  |            |..  ....... .  .  |. || |
LKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIH

SDIKPANFLIDQYDRIKISDFGLSSCYENECK----------------CC-LFKGTKLFMAPEIFSK------TDYDPFSADIWSLGVTIYYIATHHYPF
 |||||| |.     .|..|||.... ....                  .  | ||  .||||. ..       .|| ...|||||| ||   || ..|.
RDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYD-TKCDIWSLGCTIIEMATGKPPW

VD-KDLD---KIPDLIIKGE---------YQDFRIKD----------------------PDLREVVRCCLTKDVSMHCTVNELLE--LPYF
 | ...     ||. .....          .  ...|                      |.... .. ||.|| .   |...||.   | .
HDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 81732.m00007.AA ULK 4-193 25 3.9e-26 89.78 In-house 58-308 (324) Show / Hide 
Range on Protein: 4-193
Range on HMM: 58-308/324
Sequence Identity: 25% (64 aa)

QSEIECLKAID---DPR--IVRLYQVYNFG--GFIYLLMELCKN-DLDKIYKHK---------KMTTPEELFKVVHDTVLAVKACHDRHIAHSDIKPANF
..||. .| ..    |   ||.|| ...     .||. ||.|   ||... | .         |  . .|  .. .. . . |. |.. | | ||||.| 
KNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNI

LIDQYD------------RIKISDFGLSSCYENE----CKC--CL----FKGTKLFMAPEIFS----KTDYDPFSADIWSLGVTIYYIATHHYPFVDKDL
||   .            ..||.|||..   .|.    ..|  |.     ||| |.|||.|..    . .|. . .||||||. .|.. .  |||.    
LIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-F

DKIP----DLIIKG------EYQ---DFRIKD------PDLREVVRCCLTKD
 .      .|| .|      ...   .|....      |....  |..|..|
NDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYD
Kinase 81732.m00007.AA ULK 4-193 22 6.4e-26 87.53 In-house 58-313 (329) Show / Hide 
Range on Protein: 4-193
Range on HMM: 58-313/329
Sequence Identity: 22% (59 aa)

QSEIECLKAIDDPR--------IVRLYQVYNFGGF--IYLLMELCKN-DLDKIYKHK----------KMTTPEELFKVVHDTVLAVKACHDRHIAHSDIK
..||. .| ...|         ||.|| ...   .  ||. ||.|   ||... | .          |  . .|  .. .. . . |. |.. | | |||
KNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIK

PANFLIDQYD------------RIKISDFGLSSCYENE-------CKCC---LFKGTKLFMAPEIFS----KTDYDPFSADIWSLGVTIYYIATHHYPFV
|.| ||.  .            ..||.|||..   .|.       . |    ...|| |.|||.|..    . .|. . .||||||. .|.. .  .||.
PQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFY

DKDLDKIPDLIIKGEYQD------------FRIK--------DPDLREVVRCCLTKD
     .  ..||. ....            ....         |....  |..|..|
AW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYD
Kinase 81732.m00007.AA CAMKK-Unclassified 63-171 29 9.3e-26 80.64 In-house 186-350 (392) Show / Hide 
Range on Protein: 63-171
Range on HMM: 186-350/392
Sequence Identity: 29% (49 aa)

DTVLAVKACHDRH---------------------IAHSDIKPANFLIDQYDR-----IKISDFGLSSCYENECKCCLF--KGTKLFMAPEIFSKT--DYD
.  .... .|..                      | | |||| | |||. |.     .||.|||.|   | | .  |.   ||. ||||| .||    ||
QCCKGLQYMHNFNQACSYIIIYINEFDKIDHFQDIIHRDIKPQNILIDHEDNDKGEHFKIADFGISVIMEHEQQKKLKNNAGTYCFMAPEFWSKENFKYD

PFS-------------------------ADIWSLGVTIYYIATHHYPFVDKDLDKIPD-LIIKGE
.                           |||||||||.|....|  ||  |.| ..   .|...|
YNDYSFLPGTFNPLRKTYRIERICFYKKADIWSLGVTFYCMVYHSLPFWHKNLQELFHQMICQKE
Kinase 81732.m00007.AA QIK 6-170 30 5.5e-25 89.33 In-house 48-233 (272) Show / Hide 
Range on Protein: 6-170
Range on HMM: 48-233/272
Sequence Identity: 30% (56 aa)

EIECLKAIDDPRIVRLYQVYNFGGFIYLLMELCKN-DL-DKIYKHKK----------------MTTP---EELFKVVHDTVLAVKACHDRHIAHSDIKPA
|.. .| .. | |..||||      .|...| |.| .. | . || .                |  |   .|  ..  ....||. ||.|.|.| |.|  
EVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAE

NFLIDQYDRIKISDFGLSSCYENECKCCLFKGTKLFMAPEIFSKTDYDPFSADIWSLGVTIYYIATHHYPFVDKDLDKIPDLIIKG
| |.|.   ||| |||.|  ....     . |.  . |||.|   .||   .||||.||  |   .   ||  | | .  . .. |
NILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSG
Kinase 81732.m00007.AA TyrKc 2-207 17 3.8e-07 -107.11 SMART 1-280 (280) Show / Hide 
Range on Protein: 2-207
Range on HMM: 1-280/280
Sequence Identity: 17% (49 aa)

FS-----------------------------------QSEIECLKAI--DDPRIVRLYQVYNFG-------GFIYLLMELCKN-DLDKIYKHKKM-TTPE
 .                                    .|.. .. .  . | ||||| |   .       . ....||.... ||..  . ..   ...
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

ELFKVVHDTVLAVKACHDRHIAHSDIKPANFLIDQYDRIKISDFGLSSCYENE--------CKCCLF-KGTK--L---FMAPEIFSKTDYDPFSADIWSL
.| .  ..        |.... | |.   | |..   ..||||||||   ...         .     ||.|  |    |||| . .  . . | |.|| 
DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS-DVWSF

GVTIYYIATH-HYPFVD-----KDLDKIPDLIIKGEYQDFRIK---------DPDLREVVRCCLTKDVSMHCTVNELLELP
||... | |    |  .     .. . .  .. .|.. .              ... .. ..|   | .. .| .|. |. 
GVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 81732.m00007.AA CAMKK-Unclassified 4-24 42 0.011382 4.17 In-house 66-86 (392) Show / Hide 
Range on Protein: 4-24
Range on HMM: 66-86/392
Sequence Identity: 42% (9 aa)

QSEIECLKAIDDPRIVRLYQV
|.||.  | .. | |..||.|
QQEIAIMKKLWHPNICKLYEV