Gene 84302.m00316 (T.vaginalis)

84302.m00316

Species: T.vaginalis
Alias: TvagK0282, 84302.m00316
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
84302.m00316.AA Protein None 608 None Fasta, JSON
84302.m00316.kin_dom Protein Kinase Domain None 258 None Fasta, JSON

Protein domain

Protein domains of 84302.m00316.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 84302.m00316.AA TKL 20-271 23 5.7e-70 238.77 In-house 1-364 (364) Show / Hide 
Range on Protein: 20-271
Range on HMM: 1-364/364
Sequence Identity: 23% (88 aa)

IGKGSFGIVYKATDLKTN--------KIIAVKQIQFND-----------------------------PKLFLREVG-IMAKINYPSILPFLGCCLSQDP-
||.|.||.|||..   ..        | .|||..  ..                              . |..|.  .| ... | |..|.|.|.. .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

--------NTRPHLIITEYMPNKS-LDTYINQAIKGDELPNWGPTEKTIQ-MIGIAAAMRYLHRNN--------ILHRDLKPANVLLNENLE--------
        ..  . |..||.|. | |....               ..... ...|| .| ||| .|        |.|||||..|.|..||..        
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYN

------PFVCDFGLSKYVEDVNAATDQTVN-----------------VGTPVFMAPEE------YTSKY----------YNKLVDVYAYGILLYNLLTLR
      . .||||||. ..  .  .|.  .                 .||| .||||       ||.|.          |.. .|||..||.|. .|| .
PNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRC

RPFDGETCH---------SIFVKVSQ-GYRPEFP------------EGFSPLYTELIEQCWAQDPKTRPTFDMIFNVL
||.... .           .|..|.. |.||. |            . . | . .|...||..||. ||.|. |   |
RPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 84302.m00316.AA S_TKc 14-277 27 5.1e-55 190.02 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-277
Range on HMM: 1-231/231
Sequence Identity: 27% (75 aa)

SKEREDIGKGSFGIVYKATDLKTNKIIAVKQIQFNDPKLFLREVGIMAKINYPSILPFLGCCLSQDPNTRPHLIITEYMPN--KSLDTYINQAIKGDELP
 .  . ||||.|| |||... ||..| |.|.|     . ..||. |. | . | |  ..... .         ...||...   .| .|| .  ..    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK-HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

NWGPTEKTIQMIGIAAAMRYLHRNNILHRDLKPANVLLNENLEPFVCDFGLSKYVEDVNAATDQTVNVGTPVFMAPEEYTSKYYNK-LVDVYAYGILLYN
   . .    |  |. |. |.|...|.||||||.|.||.|  .  .|||||.. .         |  .||| .||||      |.|  .|... |..|| 
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

LLTLRRPFDGETCHSIFVKVSQGYRPEFPEGFSPLYTELIEQCWAQDPKTRPTFDMIFN---VLETEKFY
.|. . ||.  . . .| |.            ||   ..|..|.  ||. |||   ...   .     . 
MLCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 84302.m00316.AA Pkinase 14-271 25 3.4e-53 187.82 Pfam 1-293 (293) Show / Hide 
Range on Protein: 14-271
Range on HMM: 1-293/293
Sequence Identity: 25% (79 aa)

SKEREDIGKGSFGIVYKATDLKTNKIIAVKQIQFNDPKLFLR-------EVGIMAKINYPSILPFLGCCLSQDPNTRPHLIITEYMPNK----SLDTYIN
 .  . ||.|||| |||... .|.|| |||.|   . |   .       |. ||...| | |. ..... .   ..... ...||...     .| .|| 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED---KDHIY-MVMEYCEGGLYVMDLFDYIS

QAIKGDELPNWGPTEKTIQMI--GIAAAMRYLHRNNILHRDLKPANVLLNENLEP----FVCDFGLSKYVEDVNAATDQTVNVGTPVFMAPEEYT-SKYY
     .. .    .|......   |. .. |.|...|.||||||.|.|...| ..     .|||||.| ..     .  |. .||| .||||    ..||
T---WRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYY

NKLVDVYAYGILLYNLLTLRRPFDGE----TCHSIFVKVSQGYRPEFPEGFS-----------------------PLYTELIEQCWAQDPKTRPTFDMIF
 . ||....|..|| .|. | ||.|.    . |.  ... .  .|.... ..                       .   ..|. |...||| |||.. |.
GPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQIL

NV--L
.   .
QHPWF
Kinase 84302.m00316.AA Dicty5 123-275 37 4.8e-48 163.47 In-house 111-260 (260) Show / Hide 
Range on Protein: 123-275
Range on HMM: 111-260/260
Sequence Identity: 37% (58 aa)

IGIAAAMRYLHRNNILHRDLKPANVLLNENLEPFVCDFGLSKYVEDVNAATDQTVNVGTPVFMAPEEYTSKYYNKLVDVYAYGILLYNLLTLRRPFDGET
|.|| .||.||  || |||||  |.|..||..  . ||| | .|.   ..   |..|||. .||.| .... |   .|||..|| |. ..|   |.|  .
IDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVD---NRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEMFTRKEPYDNIN

CHSIFVKVSQGYRPEFPEGFSPLYTELIEQCWAQDPKTRPTFDMIFNVLETEK
  .| | |  | ||. |      .  ||. || | |. ||.|  |  ..|   
NWNIPVMVMKGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase 84302.m00316.AA TKL-Unique 18-271 29 1.7e-47 164.12 In-house 3-290 (290) Show / Hide 
Range on Protein: 18-271
Range on HMM: 3-290/290
Sequence Identity: 29% (88 aa)

EDIGKGSFGIVYKATDLKTNKIIAVKQIQF-NDPK-L----FLREVGIMAKIN-YPSILPFLGCCLSQDPNTRPHLIITEYMPNKSLDTYINQ-------
. || |..| |||..  ..  ..|.||. . .|.       | .|| .| |..  | |. . | |  . .      |..||.|  ||. ...|       
NKIGEGGYGQVYKGKWRGY--PVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

AIKGDELPNWGPTEKTIQM-IGIAAAMRYLHRNN--ILHRDLKPANVLLNEN-----LEPFVCDFGLSKYVEDVNAATDQ-------TVNVGTPVFMAPE
 ..  .|..    .. ..| | || .| |||...  |.|||||. |.|...|     .   .|||||||     |. |         ....|..  ||||
NNNNCKLNM----QQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPE

EYTS--KYYNKLVDVYAYGILLYNLLTLRR------PFDGETCHSIFVKVSQ---GYRPEFPEGFSPLYTELIEQCWAQDPKTRPTFDMIFNVL
. ..  . |.. .|||..|| |. ..|  .      |..| .  ... .| .   .|||. |.   . |..||.|||..||  ||.|| | . |
VLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 84302.m00316.AA Ciliate-E2 14-269 22 7.6e-47 158.84 In-house 1-361 (365) Show / Hide 
Range on Protein: 14-269
Range on HMM: 1-361/365
Sequence Identity: 22% (84 aa)

SKEREDIGKGSFGIVYKATDLKT-----------------------NKIIAVKQIQFNDPKLFLREVGIMAKIN----------------YPSILPFLGC
 |  . ||.|.||.|||... |.                       .||.|.|... |. . ...|  || .||                 | |. .  |
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

CLSQDPNTRPHLIITEYMPNKSLDTYINQA-IKGDELPN--WGPTEKTIQ--MIGIAA---------------AMRYLHRNN-ILHRDLKPANVLLNENL
  ..| |.    ...||   ..|  ||..  .| .. ..    .||| |.  |  |.                |..||| .| |.|||.|| |.|.    
FQEKDDNN--IYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

EPFVCDFGLSKYVEDV----------NAATDQTV--------------------NVGTPVFMAPEEYTSKY---------YNKLVDVYAYGILLYNLLTL
 ....||||||.. |           .  ..  .                     .||| .|||| . .|          |.. .|... |..|| .|. 
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

RRPFDGETCHSIFVKVSQGYRPEFP------------------EGFSPLYTELIEQ----CWAQDPKTRPT-FDMIFN
..||          .  .    .||                  .  |.    || .    .   ||. |.| .. |.|
KPPF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN
Kinase 84302.m00316.AA MLK 14-271 27 1.3e-46 159.72 In-house 1-291 (291) Show / Hide 
Range on Protein: 14-271
Range on HMM: 1-291/291
Sequence Identity: 27% (85 aa)

SKEREDIGKGSFGIVYKATDLKTN---KIIAVKQIQ---FNDPKL----------FLREVGIMAKIN-YPSILPFLGCCLSQDPNTRPHLIITEYMPNKS
 .. | ||.|||| |.|..  ...   ||.|||..    | |             . |.. |. . |  |.| .|.|.||.. ..    .|..||... |
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHF---CIVMEYCEGGS

LDTYINQA----------------IKGDELPNWGPTEKTIQMIGIAAAMRYLHRNN---ILHRDLKPANVLLNE------NLEPFVCDFGLSKYVEDVNA
| .... |                .. | . ||        .  .| .| ||| .    | |||||. |.|. |      ..   .||||.|. . .   
LYNVLHGARSKWMDANHNQKNDRVYDHDHAMNW--------ALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-

ATDQTVNVGTPVFMAPEEY---TSKYYNKLVDVYAYGILLYNLLTLRRPFD--GETCHSIFVKVSQGYRPEFPEGFSPLYTELIEQCWAQDPKTRPTFDM
 |  . | ||. .||||      .  |.. .||. .|..|. .|| . |..   .    ..  .  | ||  | ....   .|..||| |||. ||.|..
-TNMMSNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQ

IFNVL
|   |
IVQHL
Kinase 84302.m00316.AA LRRK 14-273 24 1.8e-46 160.73 In-house 1-351 (351) Show / Hide 
Range on Protein: 14-273
Range on HMM: 1-351/351
Sequence Identity: 24% (90 aa)

SKEREDIGKGSFG-IVYKATDLKTN---------------------------KIIAVKQIQF-------------------------------------N
 |. | ||.|.|| .||.|. .. .                           . .|.|.. .                                     .
LKIEEQIGRGGFGTFVYRAK-WRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCR

DPKLFLREVGIMAKINYPSILPFLGCCLSQDPNTRPHLIITEYMPNKSLDTYINQAIKGDEL----PN--WGPTEKTIQMIGIAAAMRYLHRNN--ILHR
   .| .|| || . | |.|.. .| |.      .|  ...||.|. .|.... .. | |..    ..  |. .   | .. || .|.|||..|  |.||
AFREFRHEVWIMSHLNHPNIVSLKGFCI------HPLCMVMEYAPHGDLYHFL-HNKKQDGFHFMKAHISWM-LKLKI-ALQIAKGMEYLHSHNPPIIHR

DLKPANVLLNENLEPF------------VCDFGLSK--YVEDVNAATDQTVNVGTPVFMAPE--EYT-SKYYNKLVDVYAYGILLYNLLTLR-RPFDGET
|||. |.||..  ...            ..|||.|   ..    .| .    ||.|..||||   |.  . |.  ||.|..|..|. |||.. .|||. .
DLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGC---VGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHD

----C--HSIFVK-VSQGYRPEFPEG-FSP-----LYTELIEQCWAQDPKTRPTFDMIFNVLET
       .... . .. | || .|.    |      | .||..||..||| ||.|  |. .|..
FFDHMQWMEQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 84302.m00316.AA Dicty4 53-273 35 5e-46 151.58 In-house 45-277 (277) Show / Hide 
Range on Protein: 53-273
Range on HMM: 45-277/277
Sequence Identity: 35% (83 aa)

FLREVGIMAKINYPSILPFLGCCLSQDPNTRP--HLIITEYMPNKSLDTYINQ----AIKGDELPNWGPTEKTIQM-IGIAAAMRYLHR-N-NILHRDLK
|..|| ||.||  | |. |.| |..  |   |   .| |||||  .| . ..       . ..|. |.  .. ..| . .|  | .||  | .|.|||||
FRKEVHIMCKIRHPNICLFMGACTA--PRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIKLD-WPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLK

PANVLLNENLEPFVCDFGLSKYVEDVNAATD-QTVNVGTPVFMAPEEYTSKYYNKLVDVYAYGILLYNLLTLRRPFD--GETCHSIFVKVSQ-GYRPEFP
..| |  .|.   |||||||.|   .   .| |.  .|||  ||||   .. ||  .||| .||.|. .||   |.   .     ..  | . . ||. |
SHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIP

EGFSPLYTELIEQCWAQDPKTRPTFDMIFNV--LET
  ..| ...||. ||  ||. ||.|  | .   ||.
DWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase 84302.m00316.AA STE 15-263 25 5.6e-45 155.75 In-house 1-347 (359) Show / Hide 
Range on Protein: 15-263
Range on HMM: 1-347/359
Sequence Identity: 25% (90 aa)

KER-EDIGKGSFGIVYKATDLK---------------TNKIIAVKQIQFNDPK--------------------LFLREVGIMAKIN--YPSILPFLGCCL
 |. | ||||.|| |||| . |               |..|.|.||. ... .                     .|.|. || | |   | |  ..||..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

SQDPN--TRP-HLIITEYMPNKSLDTYINQA-IKGDELP-----NWGPTEKTIQMIGIA--AA-MRYLHRNNILHRDLKPANVLLNENLEPFVCDFGLSK
  ..|   .    |. |||.. |||  |..  ..|..|.     ..   |. |  |  .   . . |||...| |||.||||.||        ||||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

YVEDVNA------------ATDQT--VNVGTPVFMAPEEYTS------KYYNKLVDVYAYGILLYNLLTLRRPF-DGETCHSIFVKVSQ-----------
 ..| .|             ..|     |||| .||||  .       | |.  .|..  |...  ..| . |. |.     .| .              
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---GYRPEFPE-------------------GFSPLYTELIEQCWAQDPKTRPT
   |  | .|.                    .||   . |..|   ||. |||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPT
Kinase 84302.m00316.AA Ciliate-E2-Unclassified 14-269 22 1.5e-42 145.42 In-house 1-348 (352) Show / Hide 
Range on Protein: 14-269
Range on HMM: 1-348/352
Sequence Identity: 22% (80 aa)

SKEREDIGKGSFGIVYKATDLKTN-----------KIIAVKQIQFNDPKLFLREVGIMAK----------------INYPSILPFLGCCLSQDPNTRPHL
 |  . ||.|.||.|||. . |..           .|...|||...|  . . .  .. |                .| |...    .   || ..    
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQN--IY

IITEYMPNKSLDTYINQAIK----GDELPNWGPT-----EKTIQ-------MIGIAAAMRYLHRNN-ILHRDLKPANVLLNENL---EPFVCDFGLSKYV
|..||.....|  ||..  |    |..| .   .     |. ..       .  |  .  |||..| |.|||.|| |.|...|    .. ..|||.||. 
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKY

EDVNAATDQTVN---------------VGTPVFM----APEEYTS-KYYN---KLVDVYAYGILLYNLLTLRRPFDGETCHS----------------IF
.. |  .  | .               .||| .|    ||| . . .|..   . .|... |..|| .|. ..||....| .                ..
QQNNNCD--TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLY

VKVSQG--YRPEFPE-----GFSPLYTELIE----QCWAQDPKTRPTFDMIFN
 .  |.  . |.||.     . || . ..|.    ..   .|. |.||. |.|
QNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILN
Kinase 84302.m00316.AA TK 14-271 15 7.7e-42 137.55 In-house 1-486 (486) Show / Hide 
Range on Protein: 14-271
Range on HMM: 1-486/486
Sequence Identity: 15% (76 aa)

SKEREDIGKGSFG---IVYKA-------------------------TDLKTNKIIAVKQIQF---NDPKL--------------FLREVGIMAKIN----
 .  . .|.| ||    |||.                            ...   |||..     ....               ||.|. .|.. .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-YPSILPFLGCCLSQDPNT--------RPHLIITEYMPNKS----LDTYIN--QAIKGDELPNWG-----------------------------------
  | |. ..|.|. ..|..        .| .|..||||. .    |..|       . .|... .                                   
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

---------PTEKTIQMIG-----------------------IAAAMRYLHRN------NILHRDLKPANVLLNENLE-----------PFVCDFG----
         |.  | ...                        ||..|.|||..      |. ||||   |.|..||.              ..|||    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----LSKYV---EDVNAATDQTVNVGTPV----------------------FMAPEEYT---------SKYYNKLVDVYAYGILLYNLLTLR-RPFD---
    |....   .|  ..........                          ||||  .          . .    ||...|.|.. ..|.   |.    
GSGVLARDIYSDDDYYRKSSYGTGRPM-WPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

--------GETCHSIFVKVSQG--------------YRPEFPEGFS--------------PLYTELIEQCWAQDPKTRPTFDMIFNVL
        | ... .. .. .|              .|.. |.. .              ..| .|. |||. ||. ||||. . . |
SNQDVWKDG-DNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Pkinase_Tyr 84302.m00316.AA Pkinase_Tyr 13-271 28 6.6e-38 129.01 Pfam 1-270 (270) Show / Hide 
Range on Protein: 13-271
Range on HMM: 1-270/270
Sequence Identity: 28% (80 aa)

ISKEREDIGKGSFGIVYKATDL----KTNKIIAVKQI--QFNDP----KLFLREVGIMAKI-NYPSILPFLGCCL-SQDPNTRPHLIITEYMPNKSLDTY
|.. .. .|.|.|| |||.|      .|.   ||| .  .  ..    . |.||. || .. . | |. ..|.|.  ..||   ..|..||||. .|..|
ITFGKK-LGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN--QIYIVMEYMPHGDLLDY

INQAIKGDELPNWGPTEKTIQMIG----IAAAMRYLHRNNILHRDLKPANVLLNENLEPFVCDFGLSKYV-EDVNAATDQTVNVGTPVF-MAPE---EYT
  .        ....  .. ....    ||..| ||...|. ||||   |.|..||.   .|||||.... .| .  . .. .   |.. ||||   .. 
LRKHR------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGK

SKYYNKLVDVYAYGILLYNLLTL-RRP-FDGETCHSIFVKV-SQGYRPEFPEGFSPLYTELIEQCWAQDPKTRPTFDMIFNVL
   ..   ||...|.|.. ..|. . | . | . . .. ..  .||| . ||. ..   .|. |||..||. ||||  | . |
---FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 84302.m00316.AA TyrKc 14-271 28 9.9e-38 132.59 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-271
Range on HMM: 1-280/280
Sequence Identity: 28% (82 aa)

SKEREDIGKGSFGIVYKATDLKTNKIIAVKQIQFNDPKLFLREVGIMAKI--NYPSILPFLGCCLSQDPNT---RPHLIITEYMPNKSLDTYINQAIKGD
 .  . .| | ||.|||.|        ||| .. .  . |.||  || |.  . | |. ..|.|..|  |     |..|..||||. .|. |.    .  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK-

ELPNWGPTEKTIQMIGIAAAMRYLHRNNILHRDLKPANVLLNENLEPFVCDFGLSKYVEDV---NAATDQTVN----VGT---PVF-MAPEEYTSKYYNK
      . ..   .. ||. |.|||..|. ||||   |.|..||.   ..|||||....|     ...|  .      |    |.  ||||    . .. 
----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

LVDVYAYGILLYNLLTL-RRPFDG-----ETCHSIFVKVSQGYRPEFPEG---------FSPLYTELIEQCWAQDPKTRPTFDMIFNVL
  ||...|.... ..|.   |  |      .   .. .| ||||.. |.           . .|. ...|||. ||. ||||  |   .
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
Kinase 84302.m00316.AA Dicty4 13-32 65 0.003334 6.73 In-house 1-19 (277) Show / Hide 
Range on Protein: 13-32
Range on HMM: 1-19/277
Sequence Identity: 65% (13 aa)

ISKEREDIGKGSFGIVYKAT
| .| . ||||||| |||.|
INIEQR-IGKGSFGEVYKGT