TVAG_193050

Species: T.vaginalis
Alias: TVAG_193050, TvagK1055
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Unique

Sequence

Name Sequence Type Origin Length Description Download
TVAG_193050.AA Protein None 645 None Fasta, JSON
TVAG_193050.kin_dom Protein Kinase Domain None 232 None Fasta, JSON

Protein domain

Protein domains of TVAG_193050.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

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Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase TVAG_193050.AA Dicty4 241-275 27 9.8e-10 28.83 In-house 241-277 (277) Show / Hide
Range on Protein: 241-275
Range on HMM: 241-277/277
Sequence Identity: 27% (10 aa)

PANFPNKWAILIVKCLQKNPAERPTIDQICRE--INA
|...|..|. ||..|. ..|  ||.  .|  .   ..
PDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH

Kinase TVAG_193050.AA TKL 208-273 20 1.8e-08 26.67 In-house 261-364 (364) Show / Hide
Range on Protein: 208-273
Range on HMM: 261-364/364
Sequence Identity: 20% (21 aa)

IPKEDISEKFDVYSFGAIVFEILVG-HTYK-------------------------AKSFP------------ANFPNKWAILIVKCLQKNPAERPTIDQI
..... ||| |||||| . .||| . . |.                             |             ..|  .. |. .| . .| .||. ..|
CKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEI

CREI
  ..
LKRL

Kinase TVAG_193050.AA DRK 241-275 25 3e-07 20.65 In-house 224-258 (258) Show / Hide
Range on Protein: 241-275
Range on HMM: 224-258/258
Sequence Identity: 25% (9 aa)

PANFPNKWAILIVKCLQKNPAERPTIDQICREINA
|.. | |.. |.  |.  .|  ||. ...   . |
PQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA

Kinase TVAG_193050.AA Dicty4-Unclassified 241-273 39 7.1e-07 19.55 In-house 231-263 (263) Show / Hide
Range on Protein: 241-273
Range on HMM: 231-263/263
Sequence Identity: 39% (13 aa)

PANFPNKWAILIVKCLQKNPAERPTIDQICREI
| | .| |  ||. |.   |  |||..||    
PDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL

Kinase TVAG_193050.AA NAK-Unclassified 239-275 33 1e-06 19.02 In-house 367-405 (405) Show / Hide
Range on Protein: 239-275
Range on HMM: 367-405/405
Sequence Identity: 33% (13 aa)

SFPAN--FPNKWAILIVKCLQKNPAERPTIDQICREINA
.|| |  . |.   || ..|. .| .||.| |.  .|. 
EFPSNHNYSNQLHNLIKIMLNEDPIQRPNIYQVLNHICQ

Kinase TVAG_193050.AA TK 218-273 17 2e-06 16.88 In-house 376-486 (486) Show / Hide
Range on Protein: 218-273
Range on HMM: 376-486/486
Sequence Identity: 17% (19 aa)

DVYSFGAIVFEILV-G-HTYKA-KSF------------------------------------P--ANFP--------------NKWAILIVKCLQKNPAE
||.|||  ..||.  |  .|    |                                     |  .. |                ...|. .| ...|..
DVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPED

RPTIDQICREI
||| .|. ...
RPTFSQLHEQL

Kinase TVAG_193050.AA NAK 238-273 28 2e-06 17.33 In-house 262-299 (299) Show / Hide
Range on Protein: 238-273
Range on HMM: 262-299/299
Sequence Identity: 28% (11 aa)

KSFPAN--FPNKWAILIVKCLQKNPAERPTIDQICREI
.|.| |  ....   || ..|. .| .||.|.|..  .
YSIPDNSRYSQQMHDLIRYMLTPDPEQRPNIYQVLNQL

S_TKc TVAG_193050.AA S_TKc 32-279 18 3e-06 -85.63 SMART 1-231 (231) Show / Hide
Range on Protein: 32-279
Range on HMM: 1-231/231
Sequence Identity: 18% (52 aa)

FNIGPTVERNCFGTVVDVTTVKNGESLSLAFILNLFIDRKNIADPNKFAEKIQQLTQLSHPALIKVIGIVFPGEKNRLHHAIVRENNYI--CDLSSIFEK
. |. .. .  ||.|  .. .| |.   .  |             ...   || | .  || ..| ...         |  .| |       || .. .|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------EHIRREIQILKK-HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKK

DFIHFKEVEWDNTRKSITIIGLAAALRYLHEKGLYH-------LFLVPWHILF----DSKFEPILDGFYLSSSVAHNQLY--PETTGYDSYIPKEDISE-
   | . .  .  .    .  .. || |.|..|  |       ..|   ||       ...          ...     |  ||             .  
RGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL---------TTFCGTPWYMAPEVL---------GYGKC

KFDVYSFGAIVFEILVGHT--------YKAKSFPANFPNKWAILIVKCLQKNPAERPTIDQICR---EINAGVFI
| |..|.| |..| |.| .        .|        .     .| |||||.|..|||. .. .   .|..  ..
KCDWWSCGCILYEMLCGYPPFPQMQMMFKKIG-----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase TVAG_193050.AA TKL-Unique 211-230 55 7e-05 13.36 In-house 203-222 (290) Show / Hide
Range on Protein: 211-230
Range on HMM: 203-222/290
Sequence Identity: 55% (11 aa)

EDISEKFDVYSFGAIVFEIL
...||| ||||||... ||.
CQYSEKSDVYSFGIVLWEIA

Kinase TVAG_193050.AA CZAK 214-230 58 7.7e-05 13.68 In-house 200-216 (279) Show / Hide
Range on Protein: 214-230
Range on HMM: 200-216/279
Sequence Identity: 58% (10 aa)

SEKFDVYSFGAIVFEIL
.|| |||||| |...|.
TEKVDVYSFGMILWCII

Kinase TVAG_193050.AA TKL-Unique 251-273 34 0.000112 12.62 In-house 268-290 (290) Show / Hide
Range on Protein: 251-273
Range on HMM: 268-290/290
Sequence Identity: 34% (8 aa)

LIVKCLQKNPAERPTIDQICREI
|| .|   .| .||. |.|  ..
LIQQCWHHDPSQRPSFDEIIHRL

Kinase TVAG_193050.AA RAF 251-273 39 0.000178 11.26 In-house 253-275 (275) Show / Hide
Range on Protein: 251-273
Range on HMM: 253-275/275
Sequence Identity: 39% (9 aa)

LIVKCLQKNPAERPTIDQICREI
|.. |. ..| |||.  ||  .|
LLMECWSYQPEERPSFQQIMKMI

Kinase TVAG_193050.AA Pkinase 251-273 40 0.000241 16.44 Pfam 269-293 (293) Show / Hide
Range on Protein: 251-273
Range on HMM: 269-293/293
Sequence Identity: 40% (10 aa)

LIVKCLQKNPAERPTIDQICRE--I
.| .||.|.|..|||..||.    .
FIKWCLCKDPKKRPTAEQILQHPWF

TyrKc TVAG_193050.AA TyrKc 62-273 11 0.00026 -152.93 SMART 1-280 (280) Show / Hide
Range on Protein: 62-273
Range on HMM: 1-280/280
Sequence Identity: 11% (38 aa)

FILNLFIDR--------------------KNIADPNKFAEKIQQLTQL--SHPALIKVIGIVFPG-----------------EKNRLHHAIVRENNYICD
  |.  . .                    |. |    | . .. ...|  .|| ... .|..  .                 ..  |.. . .  .    
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK---

LSSIFEKDFIHFKEVEWDNTRKSITIIGLAAALRYLHEKGLYHLFLVPWHILFDSKFEPI-----------LDGFY--------LSSSVAHN-------Q
                  .  .    .  |.  .|||.|                   ..           ..  .        ||  . .        .
----------------LCMKDLLSFCWQIACGMEYLHSK-------------------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKD

LYPETT--GYDS-----YIPKEDI-----SEKFDVYSFGAIVFEIL-VGHTYKAK---------------------SFPAN--------FPNKWAILIVK
 |  ..  | ..       . | |     ..| ||.|||   .||.  | .                           |.|         | .   .. .
YYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQ

CLQKNPAERPTIDQICREI
| . .|..|||  .|....
CWHEDPEDRPTFSEIHECF

Kinase TVAG_193050.AA CZAK 241-273 36 0.000493 10.72 In-house 244-279 (279) Show / Hide
Range on Protein: 241-273
Range on HMM: 244-279/279
Sequence Identity: 36% (13 aa)

PANFPNKWA---ILIVKCLQKNPAERPTIDQICREI
|  .. .|     || .|  ||| |||.  ||    
PQPMDPMWKNLGELIEMCWNKNPDERPSFKQILQHL

Kinase TVAG_193050.AA Pkinase_Tyr 245-273 27 0.000619 13.95 Pfam 242-270 (270) Show / Hide
Range on Protein: 245-273
Range on HMM: 242-270/270
Sequence Identity: 27% (8 aa)

PNKWAILIVKCLQKNPAERPTIDQICREI
| .   |. .| ...|..|||  .| ...
PDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase TVAG_193050.AA RAF 214-233 40 0.001069 8.56 In-house 195-214 (275) Show / Hide
Range on Protein: 214-233
Range on HMM: 195-214/275
Sequence Identity: 40% (8 aa)

SEKFDVYSFGAIVFEILVGH
|.. |||.|| . .|.. |.
SFQSDVYAFGTVWYELMAGE

Kinase TVAG_193050.AA Dicty4 215-230 68 0.053599 2.65 In-house 196-211 (277) Show / Hide
Range on Protein: 215-230
Range on HMM: 196-211/277
Sequence Identity: 68% (11 aa)

EKFDVYSFGAIVFEIL
|| |||||| . .|||
EKADVYSFGIVLWEIL

Kinase TVAG_193050.AA DRK 215-230 50 0.074311 2.11 In-house 181-196 (258) Show / Hide
Range on Protein: 215-230
Range on HMM: 181-196/258
Sequence Identity: 50% (8 aa)

EKFDVYSFGAIVFEIL
|| |||||. .  |..
EKADVYSFAIVLWECV

Kinase TVAG_193050.AA Pkinase 211-234 33 7.146065 0.63 Pfam 187-210 (293) Show / Hide
Range on Protein: 211-234
Range on HMM: 187-210/293
Sequence Identity: 33% (8 aa)

EDISEKFDVYSFGAIVFEILVGHT
.... | |..|.| |..| | |..
QYYGPKVDMWSCGCILYEMLCGRP

Sel1 TVAG_193050.AA Sel1 354-389 22 4.4e-08 29.97 Pfam 1-43 (43) Show / Hide
Range on Protein: 354-389
Range on HMM: 1-43/43
Sequence Identity: 22% (10 aa)

TDAQFAIA--ARFLEGK--G-VQR-N-PHH-AERFFTLAAEGGN
  ||....    ...|.  | | . . .   | .....||| |.
P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH

Sel1 TVAG_193050.AA Sel1 483-514 18 0.072298 9.34 Pfam 1-43 (43) Show / Hide
Range on Protein: 483-514
Range on HMM: 1-43/43
Sequence Identity: 18% (8 aa)

SDAQYEYA--L--ALAD----SRR---FTE-ASQYLRLAANAGH
. |||...  .     .     ..   . . | .....||..||
P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH

Sel1 TVAG_193050.AA Sel1 569-603 22 0.00047 16.6 Pfam 1-43 (43) Show / Hide
Range on Protein: 569-603
Range on HMM: 1-43/43
Sequence Identity: 22% (10 aa)

PIAKYKLG--KMMFDGV----MTR-N-MKD-GVSLMKAAADSGL
| | |.||   | ..|      .. .  .  .. ... ||. | 
P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH

Sel1 TVAG_193050.AA Sel1 604-630 25 0.603883 6.28 Pfam 1-34 (43) Show / Hide
Range on Protein: 604-630
Range on HMM: 1-34/43
Sequence Identity: 25% (9 aa)

IEAAKDVA--NAYRYGI--G-VPQ-N-IEI-AEAY
  |.  ..   .| .|.  | ||| . .|  | ..
P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYW