Gene 95674.m00231 (T.vaginalis)

95674.m00231

Species: T.vaginalis
Alias: 95674.m00231, TvagK0640
External Links:
Annotation:

Classification

Group: PKL
Family: PIK
Subfamily: FRAP

Sequence

Name Sequence Type Origin Length Description Download
95674.m00231.AA Protein None 2063 None Fasta, JSON
95674.m00231.kin_dom Protein Kinase Domain None 239 None Fasta, JSON

Protein domain

Protein domains of 95674.m00231.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 95674.m00231.AA PIKK 1872-1972 34 9.4e-21 72.52 In-house 162-262 (290) Show / Hide 
Range on Protein: 1872-1972
Range on HMM: 162-262/290
Sequence Identity: 34% (35 aa)

PTREDDLRKALWAMSSSSDEWYEKCEGFSSSLSYTSCVGSLVWLGGRCPSNILVNSKTGEITHIDFSLAFKGGLKLIQFTDEVPFRLTPMLVSALGIGGL
.|  |...|..| .......|.|. | . .|.   . ||    || | |.||.... |||| |||| ..|  . .   .   ||||||...| |.|. |.
NTPPDMFKKWFWRKFPDPEIWWERRENYTRSYAVMCMVGYILGLGDRHPENIMIDMQTGEIVHIDFGCCFESAMQRLPVPEKVPFRLTRNMVNAMGPMGV

N
.
E
Kinase 95674.m00231.AA FRAP 1762-1972 31 3.6e-18 63.44 In-house 1-213 (251) Show / Hide 
Range on Protein: 1762-1972
Range on HMM: 1-213/251
Sequence Identity: 31% (68 aa)

EYNFLIRGQDSTIFNARATQFQMLIKLFLRRALGNSAEFPLTIN--NLIQISHNISLIQYYRDSQFLEQVITKYRQQIQVDHLIEIRDISNLTTQRVDQL
|| ||..|..      |  |   ||   |.    ..    | |    .| .| |  || . ..   |.  |  ||.. ..   || . | .   .  |.|
EYHFLLKGHEDIRQDERVMQLFGLINRLLHNNP-ETQKKNLSIQRYSIIPLSMNTGLIGWVHHCDTLHILIRDYRKKYHIRYNIEYN-IMDRMCNDYDHL

RPIQRLEALNEI--PTREDDLRKALWAMSSSSDEWYEKCEGFSSSLSYTSCVGSLVWLGGRCPSNILVNSKTGEITHIDFSLAFKGGLKLIQFTDEVPFR
  ... |    |   |  .||.| ||  | .|. |.|.   .  ||   | .| .  || | ||||. .  || | ||||   |   ..  .| . .|||
PLMNKVEIFRYIMNNTKGEDLKKLLWLKSPNSEIWFERRTNYTRSLATMSMAGYILGLGDRHPSNIMLQRYTGKIVHIDFGDCFEVAMRREKFPEKIPFR

LTPMLVSALGIGGLN
|| ||| |. . |..
LTRMLVNAMEACGIE
Kinase 95674.m00231.AA ATM 1892-1975 39 2.2e-13 38.71 In-house 133-215 (304) Show / Hide 
Range on Protein: 1892-1975
Range on HMM: 133-215/304
Sequence Identity: 39% (33 aa)

WYEKCEGFSSSLSYTSCVGSLVWLGGRCPSNILVNSKTGEITHIDFSLAFKGGLKLIQFTDEVPFRLTPMLVSALGIGGLNTSF
|.||   .  |    | || .. || |   |||.| .  |. |||   ||  | |..   . ||||||  .|  .|| |    |
WFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQG-KILPTPETVPFRLTRDIVDGMGITGVEGVF
Kinase 95674.m00231.AA ATR 1889-2000 26 5.6e-13 40.13 In-house 157-267 (267) Show / Hide 
Range on Protein: 1889-2000
Range on HMM: 157-267/267
Sequence Identity: 26% (30 aa)

SDEWYEKCEGFSSSLSYTSCVGSLVWLGGRCPSNILVNSKTGEITHIDFSLAFKGGLKLIQFTDEVPFRLTPMLVSALGIGGLNTSFIPNFVKIHSIFSD
. .||   | .  |    . || .. || |   |||... .||. |.|. . |  | . ..  . ||||||  .| ..|  . .  |    . |  ...|
PQQWYSSRENYCRSYAVWCMVGYIIGLGDRHTDNILIDKINGECVHVDYNCIFNSG-EQFEVPEIVPFRLTHNMVFGMGPMKTYGLFRRACEVIMMCMRD

FSYLILPSFYLY
    |.  .  .
HRDDIMSVWDCF
Kinase 95674.m00231.AA PI3_PI4_kinase 1872-1967 28 4.5e-11 42.63 Pfam 139-244 (300) Show / Hide 
Range on Protein: 1872-1967
Range on HMM: 139-244/300
Sequence Identity: 28% (30 aa)

PTREDDLRKALWAMSSSS-DEWYEKCEGFSSSLSYTSCVGSLVWLGGRCPSNILV--NSKTGEITHIDFSLAFK-GGLKLIQFTDEVPFRLTP------M
.|  ..|.. .| .. .  .|| |  . | .|. . . |. .  .| | ..||.|  . .||.. |||| ..|     |   . ..||||.|.      .
KTPKPGLYQWFWKHNPDAYEEWWEARDNFVRSCAGMCVVDYILGNGDRHNDNIMVKDDKTTGHLFHIDFGHCFPHWKMKHFHKPERVPFRWTHWPQAKKP

LVSALG
.|.|.|
MVHAMG
Kinase 95674.m00231.AA PI3Kc 1772-2056 15 9.1e-09 -24.88 SMART 1-336 (336) Show / Hide 
Range on Protein: 1772-2056
Range on HMM: 1-336/336
Sequence Identity: 15% (54 aa)

STIFNA--------RATQFQMLIKLFLRRA-LGNSAEFPLTINNLIQISHNISLIQYYRDSQFLEQVI-TKYRQQIQVDHLIEIRD--------------
. || .        |. |.  |..  ...    .   . ... . | .. .. .|.   ..  | |.  ... .. ... .....               
AVIFKCGDDLRQDMRMMQMFRLMNKIWQKDKECRRRDLHMRPYKCIPTGPKCGMIEWVPNCETLHQIQKKYHKWKKMPMDYHQWFMFDMLVPEIQKNMYM

ISNLTTQRVDQLRPIQ-------RLEALNEIPTREDDLRKALWAMSSSSD-EWYEKCEGFSSSLSYTSCVGSLVWLGGRCPSNILVNSKTGEITHIDFSL
 ...............        ..  .  |. ...|.. .| .. ... .|.|  . | .|. . ..|. .  .| | ..||..  |||.. ||||  
MIWHQQACHWMMMYQHMTHMEWLKYFEGATCPFKPPVLYDWFWEHFPDPNEDWWEARDNFTRSCAGYCMVTYILGIGDRHNDNIMLDMKTGHCFHIDFGH

AFKGGLKLIQFT----DEVPFRLTPMLVSALG----IGGLNTSFIPNFVKIHSIFSDFSYLILPSFYLYAEEPP-LPFIGQPSFETKREILDNVFDVL-Y
.|  | |.. |.    . ||||||...| . |    . |.   |    ...  ..   | ||.  | ...  |    . ..   | . . | . | .  .
IFGHGPKKPGFKHHHRERVPFRLTHDMVYVMGGGGKPSGYFGYFRTCCCRAYRAMRKHSNLIMNLFEMMVYDPIMPCWRMM---EKDIKYLRQRFRLDHL

SQKETPES--------YVQRLIDAATNKY----SLAKQH
| .|  .         . . .... |...     . .|.
SDEEAAQYFMQTMCTKLIEHSNESWTTRMYWMFHNWAQY
Kinase 95674.m00231.AA SMG1 1878-1947 37 2.9e-08 23.31 In-house 169-238 (242) Show / Hide 
Range on Protein: 1878-1947
Range on HMM: 169-238/242
Sequence Identity: 37% (26 aa)

LRKALWAMSSSSDEWYEKCEGFSSSLSYTSCVGSLVWLGGRCPSNILVNSKTGEITHIDFSLAFKGGLKL
| | ||.     |||.     .  |    | || .. || |   |.|.   |||. |||.   |  | ||
LAKELWSSCTTPDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYPICFEKGKKL
Kinase 95674.m00231.AA PIKK 1734-1771 28 6e-07 21.72 In-house 2-39 (290) Show / Hide 
Range on Protein: 1734-1771
Range on HMM: 2-39/290
Sequence Identity: 28% (11 aa)

LALVKDDLIVIPVKTRPRQITLLGKDGNEYNFLIRGQD
 .   . ..|.. |..|. |...| || || .|  | .
IRFMDRMVTVMAHKQKPKKIYIRGHDGKEYPYLCKGHE
Kinase 95674.m00231.AA SMG1 1741-1782 33 4e-06 15.97 In-house 1-42 (242) Show / Hide 
Range on Protein: 1741-1782
Range on HMM: 1-42/242
Sequence Identity: 33% (14 aa)

LIVIPVKTRPRQITLLGKDGNEYNFLIRGQDSTIFNARATQF
. ..| ||.|...  || ||  | .| .| .      |  ||
ITILPTKTKPKKLLFLGSDGKSYPYLFKGLEDLHLDERIMQF
Kinase 95674.m00231.AA FATC 2031-2063 33 1.3e-05 21.04 Pfam 1-33 (33) Show / Hide 
Range on Protein: 2031-2063
Range on HMM: 1-33/33
Sequence Identity: 33% (11 aa)

QKETPESYVQRLIDAATNKYSLAKQHSTWRPFW
.. ..|  |.|||. ||. . |..  . | |.|
EPLSVEQQVDRLIQEATDPENLCQMYIGWCPWW
Kinase 95674.m00231.AA ATR 1734-1792 25 0.019947 3.59 In-house 3-61 (267) Show / Hide 
Range on Protein: 1734-1792
Range on HMM: 3-61/267
Sequence Identity: 25% (15 aa)

LALVKDDLIVIPVKTRPRQITLLGKDGNEYNFLIRGQDSTIFNARATQFQMLIKLFLRR
.|   | . ..    .|..|.| | ||  |  . . .|    . |  .|. ||   .|.
IAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCREMRFNELINFCNRK