Gene 93793.m00206 (T.vaginalis)

93793.m00206

Species: T.vaginalis
Alias: TvagK0753, 93793.m00206
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK-Tvag2

Sequence

Name Sequence Type Origin Length Description Download
93793.m00206.AA Protein None 363 None Fasta, JSON
93793.m00206.kin_dom Protein Kinase Domain None 270 None Fasta, JSON

Protein domain

Protein domains of 93793.m00206.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 93793.m00206.AA Ciliate-E2 83-352 21 1.4e-31 105.66 In-house 1-365 (365) Show / Hide 
Range on Protein: 83-352
Range on HMM: 1-365/365
Sequence Identity: 21% (82 aa)

WLFLQELCNGTTSQIYLVKNVETQAVC-----------------VAKVYNNSILYRQPLGNEIPPIDSFNKEID----------VMCQLTYLHIMSYHEM
  |.. ...|. ...|..|. ..|                    |.. . .   ...   ..|  ... ..||.          .. ||   .|. ..| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VDDQMTNSKILVLPYASLGNLKTAMSNNQIS-------------YENLIVCWYQIAG--------------ALDYMHSHG-LAHRDVCPENILVFVENYF
  .. .|.  ||. |.. |.|.  . ||...             .| . . .... |              || |.|| .   |||  |||||.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

CIHHFKSVTKVDSP-----------------DLSRTFG----------------TFRFLAPEELNGKTYDV--------RKSDVWELGITIYWAFFRKKP
.|  |   .|.| .                 | |||.|                |  ..||| |||| ||          |.|.| ||...|.  | | |
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FDLDIVQIDDKPYKYDKLYQHIMQKPLEIP----------------KIDSISTEITDLLST----MLEKDPDKRPN-FATILESHVL
|                 .| |.|.....|                . ...| |  ||..     ||.|||.||.. .  ||. . .
F-----------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 93793.m00206.AA S_TKc 83-353 20 2.6e-29 104.6 SMART 1-231 (231) Show / Hide 
Range on Protein: 83-353
Range on HMM: 1-231/231
Sequence Identity: 20% (60 aa)

WLFLQELCNGTTSQIYLVKNVETQAVCVAKVYNNSILYRQPLGNEIPPIDSFNKEIDVMCQLTYLHIMSYHEMVDDQMTNSKILVLPYASL--GNLKTAM
. .|...  |. .. |......|. ..  |. .                ... .||... .    .|  .... .|   ..  .|. |..   |.|.. .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYI

SNNQ-------ISYENLIVCWYQIAGALDYMHSHGLAHRDVCPENILVFVENYFCIHHFKSVTKVDSPDLSRTFGTFRFLAPEELNGKTYDVRKSDVWEL
 ...       ..        |||. ||.|.||||  |||. |||||.       |  | . ...     .   ||  ..||| |    |. .|.|.| .
KKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSC

GITIYWAFFRKKPFDLDIVQIDDKPYKYDKLYQHIMQKPLEIPKIDSISTEITDLLSTMLEKDPDKRPNFATILE------SHVLM
|...|  . .. ||.            .......|.            | |  |... .|.|||.|||    .|.      .|  .
GCILYEMLCGYPPFP-----------QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 93793.m00206.AA Ciliate-E2-Unclassified 83-352 20 1.8e-24 81.85 In-house 1-352 (352) Show / Hide 
Range on Protein: 83-352
Range on HMM: 1-352/352
Sequence Identity: 20% (71 aa)

WLFLQELCNGTTSQIYLVKNVETQAV------CVAKVYN-NSILYRQPLGNEIPPIDSFN--------KEID-VMCQLTYLHIMSYHEMVDDQMTNSKIL
  ... ...|  ...|.... ... .      .....|. ..|.. . . ||.  . . .        |. .  . ..  ..|. ....  |. .   ..
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQN--IYI

VLPYASLGNLKTAMSN------------------NQISYENLI-----VCWYQIAGALDYMHSHG-LAHRDVCPENILVFVEN---YFCIHHFKSVTKVD
|. |.  |.|.  ...                  .... .. .        .||  .|.|.|. .   |||  |||||.  ..   | .|  | .  | .
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

----------------SPDLSRTF-GTFRFL----APEELNGKTYDVR---KSDVWELGITIYWAFFRKKPFDLDIVQIDDKPYKYD--------KLYQH
                ..... || || ...    ||| | |. || .   |.|.| ||. .|.  | . ||. |  ..... ...          ||| 
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFY-DNNCEQHQQLITQWINNAYRKQLYQN

IMQKPLEIPKID------SISTEITDLLS----TMLEKDPDKRPNFATILESHVL
|.||....|| .       .| |  |...     ||.|.|.||..|  ||. . .
IKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 93793.m00206.AA MELK 83-352 26 7.7e-22 71.14 In-house 1-254 (254) Show / Hide 
Range on Protein: 83-352
Range on HMM: 1-254/254
Sequence Identity: 26% (72 aa)

WLFLQELCNGTTSQIYLVKNVETQAVCVAKVYNNSILYRQPLGNEIPPIDSFNKEIDVMCQLTYLHIMSYHEMVDDQMTNSKILVLPYASLGNL-KTAMS
.   .|.  |  ... |   . |.     |     |. .. ||...| .     |.| . .| . ||   . ...    .   .|. | . |..    ..
YEVHDEIGTGGFAKVKLACHILTNQMVAIK-----IMDKNQLGHDLPRVKT---EMDALKNLRHQHICQLYHYIE--TEDKIFMVMEYCPGGEMFDYIIR

NNQISYENLIVCWYQIAGALDYMHSHGLAHRDVCPENILVFVENYFCIHHF----KSVTKVDSPDLSRTFGTFRFLAPEELNGKTYDVRKSDVWELGITI
..... |.  . . ||  |. |.|| | ||||. |||.|.  .  . .  |    |.  ..|  .|    |   . ||| ..|| |     ||| .|| .
QDRLEEEETRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILL

YWAFFRKKPFDLDIVQIDDKPYKYDKLYQHIMQKPLEIPKIDSISTEITDLLSTMLEKDPDKRPNFATILESHVL
|  .    ||| | ..|         .|. ||.   | ||   .| |  .||  ||  ||.||     .|.   .
YVLMCGFLPFDDDNMMI---------MYKKIMSGCYEEPKW--LSPESKQLLRHMLQVDPKKRISMKNLLNHPWV
Kinase 93793.m00206.AA CAMK 196-352 21 8.1e-19 56.6 In-house 187-425 (425) Show / Hide 
Range on Protein: 196-352
Range on HMM: 187-425/425
Sequence Identity: 21% (53 aa)

QIAGALDYMHSHGLAHRDVCPENILVFVEN----------------Y--------FCIHHFKSVTKV------------------DSPDLSRTFGTFRFL
||. |..|.|||. .|||  |||||.   |                .        | .. ...                      . . ..  .||  . 
QICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYM

A-PEELNG-------------KTYDVRKSDVWELGITIYWAFFRKKPFDLD----IVQIDDKPYK----YDKLYQHIMQKPLE-IPKIDS----------
| || |||             |.|. .|.|.| .|.  |     . ||. |    |.. | .  .    . .|.. ||.   . .|.  |          
AAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICE-D-E--WIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEW

-----------ISTEITDLLSTMLEKDPDKRPNFATILESHVL
           .|.|  ||.. ||..||.||.. . .|.   .
WDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 93793.m00206.AA TKL 195-350 18 4.6e-18 61.65 In-house 139-364 (364) Show / Hide 
Range on Protein: 195-350
Range on HMM: 139-364/364
Sequence Identity: 18% (43 aa)

YQIAGALDYMHSHG--------LAHRDVCPENILVFVENY--------------FCIHHFKSVTKVDSPD---------------------LSRTFGTFR
..|| ...|.||..        ..|||  ..||||.  .                .| .|   . ..                        ...  ||.|
LDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPR

FLAPEELNGKTYDV---------------RKSDVWELGITIYWAFFRKKPF---DLDIVQIDDKPYKYDKLYQHIM-QKPLEIPKI----------DSIS
..||| |.|....                 |.||.  || ..  . |..|.   . . ... | |   . ... .  .....|| |          ... 
WMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQD-P-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCP

TEITDLLSTMLEKDPDKRPNFATILESH
... .|.    . ||.|||.| .||.  
PSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 93793.m00206.AA ULK 248-352 24 1.9e-17 57.54 In-house 213-329 (329) Show / Hide 
Range on Protein: 248-352
Range on HMM: 213-329/329
Sequence Identity: 24% (29 aa)

GTFRFLAPEELN----GKTYDVRKSDVWELGITIYWAFFRKKPFDLDIVQIDDKPYKYDKLYQ------HIMQKPLEIP---KIDSISTEITDLLSTMLE
||  . ||. |.    .| |.  |.|.| ||. .|.  . | ||     . ... .... . .       | ..||..|   ... || |. ||.. ||.
GTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQ

KDPDKRPNFATILESHVL
.|...| ..  ...  ..
YDEKDRISWEELFNHPWF
Kinase 93793.m00206.AA ULK 237-352 22 3.5e-16 53.96 In-house 187-324 (324) Show / Hide 
Range on Protein: 237-352
Range on HMM: 187-324/324
Sequence Identity: 22% (32 aa)

KVDSPDLSRTF-----------GTFRFLAPEELN----GKTYDVRKSDVWELGITIYWAFFRKKPFDLDIVQIDDKPYKYDKLYQH------IMQKPLEI
.||..... .            ||  . ||. |.    .| |.  |.|.| ||. .|.  . | ||  .  . ...  ... . .       | ..|...
HVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLY-IQKLINNGKEQQIYIKNQPIQF

P---KIDSISTEITDLLSTMLEKDPDKRPNFATILESHVL
|   |.. || |. ||.. ||..|...| ..  |..  ..
PKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 93793.m00206.AA Pkinase 248-352 25 3.7e-15 54.66 Pfam 173-293 (293) Show / Hide 
Range on Protein: 248-352
Range on HMM: 173-293/293
Sequence Identity: 25% (31 aa)

GTFRFLAPEELNGKTYDVRKSDVWELGITIYWAFFRKKPFDLDIVQIDDKPYKYDKLYQHIMQKPLEIPKIDSIS-------------------TEITDL
|| ...||| ..| .|. .|.|.| .|...|  .... ||. . .  .|. .  ..... ||..||. .   ..|                    |  |.
GTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFP-GHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDF

LSTMLEKDPDKRPNFATILESHVL
.. .|.||| |||... ||..  .
IKWCLCKDPKKRPTAEQILQHPWF
Kinase 93793.m00206.AA Ciliate-E2c 252-352 26 8.8e-13 41.21 In-house 184-310 (310) Show / Hide 
Range on Protein: 252-352
Range on HMM: 184-310/310
Sequence Identity: 26% (34 aa)

FLAPEELNGKTYDVRKSDVWELGITIYWAFFRKKPFD----LDIVQIDDK--PYKYD---KLYQHIM---------------QKPLEIPKI--DSISTEI
. ||. |.|| |.  |||.| ||.| |   ..| |..     |   |  .  |.. .   .| |||                ....  |.    .|| |.
YMAPQILEGKNYYTEKSDIWSLGVTLYYMLCYKLPWESIQEYDSHNICNHCYPWWQNTMKHLKQHIWEYFNPQASAAGVSPITQNIHFPENYEQNISQEV

TDLLSTMLEKDPDKRPNFATILESHVL
 .|.  ||..|. || ..  |     .
KQLIHKMLQVDEEKRIDWDEIFNHECI
Kinase 93793.m00206.AA CAMKL 248-352 30 7.4e-12 33.97 In-house 195-297 (297) Show / Hide 
Range on Protein: 248-352
Range on HMM: 195-297/297
Sequence Identity: 30% (34 aa)

GTFRFLAPEELNG--KTYDVRKSDVWELGITIYWAFFRKKPFDLDIV---QIDDKPYKYDKLYQHIMQKPLEIPKIDSISTEITDLLSTMLEKDPDKRPN
|.  . ||| ..|  | || .| |.| .|.. |   . . ||| | .     |.. |.| |    ||.   ..|.  ..| .  ||.. ||...|.|||.
GSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWK----IMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPT

FATILESHVL
   |..   .
IHQIMNHPWM
Kinase 93793.m00206.AA Pkinase 83-221 22 3e-11 40.84 Pfam 1-141 (293) Show / Hide 
Range on Protein: 83-221
Range on HMM: 1-141/293
Sequence Identity: 22% (35 aa)

WLFLQELCNGTTSQIYLVKNVETQA-VCVAKVYNNSILYRQP-----LGNEIPPIDSFNKEIDVMCQLTYLHIMSYHEMVDDQMTNSKIL-VLPYASLG-
. ... .  |. .. |. ... |.  |.| ..   ..   ..     |            || .|  |   .|  ..... |   ...|  |..|.  | 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-----------SEIQIMKRLNHPNIVRLYDWFED---KDHIYMVMEYCEGGL

---NLKTAMS---NNQI--SYENLIVCWYQIAGALDYMHSHGLAHRDVCPENILV
    |.. .|   .. .  |.. .. ..|||. .|.|.||.|  |||. |||||.
YVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILI
Kinase 93793.m00206.AA TyrKc 83-350 19 2.9e-10 -56.71 SMART 1-280 (280) Show / Hide 
Range on Protein: 83-350
Range on HMM: 1-280/280
Sequence Identity: 19% (57 aa)

WLFLQELCNGTTSQIYLVKNVETQAVCVAKVYNNSILYRQPLGNEIPPIDSFNKEIDVMCQL--TYLHIMSYHEMVDDQ-----MTNSKILVLPYASLGN
  ....| .|   ..|. .       .  |. ...             .  | .|. .||.|     .|   .  . .|           .|. |...|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGD

LKTAMSNNQ--ISYENLIVCWYQIAGALDYMHSHGLAHRDVCPENILVFVEN-----YF--CIHHFKS--------VTKVDSPDLSRTFGTFRFLAPEEL
||    ...  .. . |.   .|||   .| ||... |||    |.||  ..      |  .  .           . .. . . ..|    | .||| .
LKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

NGKTYDVRKSDVWELGITIYWAF-FRKKPFDLDIVQIDDKPYKYDKLYQHIMQK-PLEIPKIDS------ISTEITDLLSTMLEKDPDKRPNFATILESH
| ...   |||||  |....  | . ..|   .| |    . . . ......|   ...|. |        ..|. .. ..  . ||..||.|..| |  
NYGKFTT-KSDVWSFGVCMWEIFTYGQQPYPGMIQQ----MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 93793.m00206.AA ULK 83-221 19 2.7e-09 28.71 In-house 1-163 (329) Show / Hide 
Range on Protein: 83-221
Range on HMM: 1-163/329
Sequence Identity: 19% (32 aa)

WLFLQELCNGTTSQIYLVKNVET----QAVCVAKVYN----NSILYRQPLGNEIPPIDSFNKEIDVMCQLTYL--------HIMSYHEMVDDQMTNSKIL
.   ..|. |.  . |  .|..|    . ....|.      | ... |. | ..  ......||..| .|           .|  ....  ..  |   .
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQE-G-QY-MWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYI

VLPYASLGNLKTAMSNNQ-----------ISYENLIVCWYQIAGALDYMHSHGLAHRDVCPENILV
.. |   |.|.. ...|.           .| .  |   .||. .. ..|.|.  |||  |.|||.
IMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILI
Kinase 93793.m00206.AA CAMKL 196-221 61 7e-09 24.32 In-house 135-160 (297) Show / Hide 
Range on Protein: 196-221
Range on HMM: 135-160/297
Sequence Identity: 61% (16 aa)

QIAGALDYMHSHGLAHRDVCPENILV
||  |..|.|||| .|||  |||||.
QIVSAVNYCHSHGIVHRDIKPENILL
Kinase 93793.m00206.AA WEE 318-352 34 1.3e-08 25.1 In-house 263-297 (297) Show / Hide 
Range on Protein: 318-352
Range on HMM: 263-297/297
Sequence Identity: 34% (12 aa)

IDSISTEITDLLSTMLEKDPDKRPNFATILESHVL
...||.| ..|.  |...||..||  . .|...||
DNIISQELKQLIKWMMHPDPEQRPTCQQLLQHPVL
Kinase 93793.m00206.AA ULK 131-221 22 7.3e-08 24.05 In-house 54-159 (324) Show / Hide 
Range on Protein: 131-221
Range on HMM: 54-159/324
Sequence Identity: 22% (24 aa)

IDSFNKEIDVMCQLT------YLHIMSYHEMVDDQMTNSKILVLPYASLGNLKTAMSNNQ----------ISYENLIVCWYQIAGALDYMHSHGLAHRDV
......|| .| .|         ||  ....  ..  |   ... |   |.|.. . .|.          .| .  |   .||. .. ..|.|.  ||| 
WQLLKNEIQIMKKLKELKHPNH-HIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDI

CPENILV
 |.|||.
KPQNILI
Kinase 93793.m00206.AA WEE 196-221 40 1e-06 18.13 In-house 119-145 (297) Show / Hide 
Range on Protein: 196-221
Range on HMM: 119-145/297
Sequence Identity: 40% (11 aa)

QIAGALDYMHSH-GLAHRDVCPENILV
.|. .| ..||. |. | |. ||||..
DICQGLHHIHSNCGMVHMDIKPENIFI
Kinase 93793.m00206.AA Ciliate-E2c 196-220 50 4.9e-05 13.7 In-house 122-147 (310) Show / Hide 
Range on Protein: 196-220
Range on HMM: 122-147/310
Sequence Identity: 50% (13 aa)

QIAGALDYMHSH-GLAHRDVCPENIL
||. |. | |.  . .|||. |||||
QIISAFKYLHKEKNIFHRDIKPENIL
Kinase 93793.m00206.AA WEE 248-278 45 0.000505 9.47 In-house 195-227 (297) Show / Hide 
Range on Protein: 248-278
Range on HMM: 195-227/297
Sequence Identity: 45% (15 aa)

GTFRFLAPEELNG--KTYDVRKSDVWELGITIY
| .|..||| |.|     .  |.|.  ||||||
GDSRYMAPEILQGYYHYTHLYKADIFSLGITIY
Kinase 93793.m00206.AA CAMK 88-115 12 0.067923 1.08 In-house 1-40 (425) Show / Hide 
Range on Protein: 88-115
Range on HMM: 1-40/425
Sequence Identity: 12% (5 aa)

ELCNGTTSQIYLVKNVETQ------------AVCVAKVYN
.|  |. .. .|... .|.              . .|...
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIID