83996.m00266

Species: T.vaginalis
Alias: 83996.m00266, TvagK0280
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
83996.m00266.AA Protein None 952 None Fasta, JSON
83996.m00266.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of 83996.m00266.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 83996.m00266.AA TKL 198-444 27 3.4e-84 286.03 In-house 1-364 (364) Show / Hide
Range on Protein: 198-444
Range on HMM: 1-364/364
Sequence Identity: 27% (103 aa)

IGSGGYASVHLARLKSTN--------ELVAVKEMKASQL------------------------YARRIIFMKREIDALMK-LNHPNTIRLIGVTVTPP--
|||||.. |. .... ..        . |||| .|  .                          |... | ..|   .|. |.||| ....|.   ||  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------FCIVTNLIPNGS-FTEYIIGNGPLTTKGTPIFRLRIMLDSARGMEYLHALG--------LMHRDFKPLNILIDENER-----------
            .|||. ..|.|| .  ..           .  |.|..|| ||||.|||. .        . ||| |. |||.||| .           
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNA

---GVLCDFGLSRPFSG----------------------KKSGDLGTMQWIAPELLQ---------------HGVQYDESVDVYAFGITLWVIATSKNPY
     .||||||| .|.                      ...   || .| |||.|.               .| .|.|..|||.||| || |.| . ||
DWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPY

T--GMRQMQYA-------NLVISENLRPTPP------------DDQPPEFIKLMQRCWDSNPKKRPTFREIRQIL
   ....|. .        .|....|||..|            .| ||...||||.|||..|.|||.| || ..|
YDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase 83996.m00266.AA MLK 192-444 32 2.8e-63 216.56 In-house 1-291 (291) Show / Hide
Range on Protein: 192-444
Range on HMM: 1-291/291
Sequence Identity: 32% (94 aa)

TIIKENIGSGGYASVHLARLKSTN---ELVAVKEMK-----ASQLYARRIIFMKREIDALMKLNHPN----TIRLIGV-TVTPP-FCIVTNLIPNGSFTE
  ..| ||||.. .|...| . ..     ||||. .     .|. |. .  | ..|.  | .|.|||     |.. || . .|. ||||.  ...||  .
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDF-EMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

YIIGNGPLTT----------KGTPIFRLRIMLDSARGMEYLHALG---LMHRDFKPLNILIDE------NERGVLCDFGLSRPFSGK---KSGDLGTMQW
.. |. .               .. . ....|. ||||.|||..    . ||| |. ||||||      ..  . ||||.|| .. .   . .  ||  |
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAW

IAPELLQ--HGVQYDESVDVYAFGITLWVIATSKNPYT-GMRQMQYANLVISENLRPTPPDDQPPEFIKLMQRCWDSNPKKRPTFREIRQIL
 ||| .|   . .|.|..||. .|. || . | . ||  .. .|. |  |. ..|||. | . |. . |||..||...|.|||.||.| |.|
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL

Kinase 83996.m00266.AA Dicty4 194-446 33 8.3e-58 191.43 In-house 3-277 (277) Show / Hide
Range on Protein: 194-446
Range on HMM: 3-277/277
Sequence Identity: 33% (94 aa)

IKENIGSGGYASVHLARLKSTNELVAVKEMKASQLY--ARRIIFMKREIDALMKLNHPNTIRLIGVTV----TP-PFCIVTNLIPNGSFTEYIIGN----
| . ||.|....|.... . .   |||| ... .    . ..   ..|.. . |. ||| . . |       .|  .|||| . | |.  . .. .    
IEQRIGKGSFGEVYKGTWRGKE--VAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNL-YSLLHDKPSE

-GPLTTKG-TPIFR-LRIMLDSARGMEYLHA--LGLMHRDFKPLNILIDENERGVLCDFGLSR----PFSGKK--SGDLGTMQWIAPELLQHGVQYDESV
  . ...  . | | .|...| |||| .||.      ||| |. |.|.|.| |   ||||||.      . |   ..  ||  | ||| ..|   |.|..
QQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMH-QPYNEKA

DVYAFGITLWVIATSKNPYT--GMRQMQYANLVISENLRPTPPDDQPPEFIKLMQRCWDSNPKKRPTFREIRQI--LES
||| ||| || |.| . ||   .|  || ...| .. |||  ||. || ...|.|.||| .|..||.| || |.  ||.
DVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH

Kinase 83996.m00266.AA TKL-Unique 194-444 32 9.6e-58 198.15 In-house 1-290 (290) Show / Hide
Range on Protein: 194-444
Range on HMM: 1-290/290
Sequence Identity: 32% (95 aa)

IKENIGSGGYASVHLARLKSTNELVAVKEMKASQLYARRIIF-MKREIDALMKLN-HPNTIRLIGVTV----TPP-FCIVTNLIPNGSFTEYII------
. . ||.|||..|  .  ...   ||.|  .   .   ....  ..|.  . ||. |||  ...|...    .|| .|||.  .| ||  ...       
FWNKIGEGGYGQVYKGKWRGYP--VAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

GNGPLTTKGTPIFRLRIMLDSARGMEYLHALG--LMHRDFKPLNILIDEN-----ERGVLCDFGLSRPFS----GKKS--------GDLGTMQWIAPELL
 | .  .| ..  |... .| |.||.||| ..   .||| |..|.|.|.|      .  .||||||.  |    ....        . .|. .|.|||.|
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

QHG-VQYDESVDVYAFGITLWVIATSKN------PYTGMRQMQYANLVIS--ENLRPTPPDDQPPEFIKLMQRCWDSNPKKRPTFREIRQIL
     ||.|..|||.||| || |||.|       || || | |.. .| .  ||.||. |.. |.|. .|.|.||...| .||.| ||.  |
RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL

Kinase 83996.m00266.AA S_TKc 192-449 26 1.1e-57 198.88 SMART 1-231 (231) Show / Hide
Range on Protein: 192-449
Range on HMM: 1-231/231
Sequence Identity: 26% (72 aa)

TIIKENIGSGGYASVHLARLKSTNELVAVKEMKASQLYARRIIFMKREIDALMKLNHPNTIRLIGVTVTPPFCIVTNLIPN--GSFTEYIIGNGPLTTK-
  | . ||.|....|...| |.|...||.|..|         . ..|||. |.| .||| ..|..| ..  ...|. ....  |.  .||  .|.  .. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-GTPIFRLRIMLDSARGMEYLHALGLMHRDFKPLNILIDENERGVLCDFGLSRPFSGKKSGDLGTMQWIAPELLQHGVQYDE-SVDVYAFGITLWVIATS
  ..    ..|   ....||.| .| .||| || |||.||  .  .|||||.| .    .   ||  ..|||.|    .|.  ..|....|..|.  .. 
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCG

KNPYTGMRQMQYANLVISENLRPTPPDDQPPEFIKLMQRCWDSNPKKRPTFREIRQ----ILESGTV
. |.    || . ...             .||.. ....|.. .|.||||  |. |    |     .
YPPFP-QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 83996.m00266.AA LRRK 192-446 25 6.1e-55 188.84 In-house 1-351 (351) Show / Hide
Range on Protein: 192-446
Range on HMM: 1-351/351
Sequence Identity: 25% (89 aa)

TIIKENIGSGGYA-SVHLARLKS-------------TN-------------ELVAVKEMKA--------------------------------SQLYARR
 .| | ||.||.. .|. |....              .             . ||.| ..                                 ..  .| 
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

IIFMKREIDALMKLNHPNTIRLIGVTVTPPFCIVTNLIPNGSFTEYII---GNG----PLTTKGTPIFRLRIMLDSARGMEYLHALG--LMHRDFKPLNI
     .|.  . .||||| . |.|..   |.|.|. ..|.|.  ...     .|    .  .. .. ..|.|.|. |.||||||     . ||| |. ||
FREFRHEVWIMSHLNHPNIVSLKGFCIH-PLCMVMEYAPHGDLYHFLHNKKQDGFHFMK--AHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNI

LI---DEN-------ERGV--LCDFGLSR---PFSGK-KSGDLGTMQWIAPELLQHG--VQYDESVDVYAFGITLWVIATSK-NPYTGMR-Q-----MQY
|.   ..|       .  .  ..|||.||   .|  .  .| .|. .| ||| .. .  ..|.| ||.|.||. || . | .  |. ..        |  
LLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQ

ANLVISENLRPTPPDD-QPP-----EFIKLMQRCWDSNPKKRPTFREIRQILES
  . |.| |||| | . .||     .. .|.| ||. .|||||.| .| ..|..
IEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ

Kinase 83996.m00266.AA Pkinase 192-444 26 5.1e-51 180.6 Pfam 1-293 (293) Show / Hide
Range on Protein: 192-444
Range on HMM: 1-293/293
Sequence Identity: 26% (79 aa)

TIIKENIGSGGYASVHLARLKSTNELVAVKEMKASQLYARRIIFMKR--EIDALMKLNHPNTIRLIGVTVTPP-FCIVTNLIPNG----SFTEYII--GN
  |.. ||||....| ... |.|...||||..| .       .   |  ||  . .||||| .||...  ...  ..|. . ..|    .  .||    .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GPLTTKGTPIFRLRIMLDSARGMEYLHALGLMHRDFKPLNILIDENERG----VLCDFGLS----RPFSGKKSGDLGTMQWIAPELLQHGVQYDESVDVY
|...  ...    ..|.  .||.||.|. | .||| || |||||.|        .|||||.       ..  ..  ||  ..|||....|  |. .||..
GCFY--FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

AFGITLWVIATSKNPYTGM------RQMQYANLVISENLRPTPPDDQP-------------------PEFIKLMQRCWDSNPKKRPTFREIRQI--L
..|..|.  .. . |. |       .|||  ... .  |.   | . .                   .|..... .|.. .||||||...| |   .
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 83996.m00266.AA TK 192-444 16 4.5e-48 158.82 In-house 1-486 (486) Show / Hide
Range on Protein: 192-444
Range on HMM: 1-486/486
Sequence Identity: 16% (78 aa)

TIIKENIGSGGYA---SVHLARLKSTN-------------------------ELVAVKEMK--ASQLYARRII-FMK---------REIDALMKLN----
 .. . .|.| .     |....... |                         . |||| .|  ...  ....  .|.         .|  ......    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNTIRLIGVTVT-------------PPFCIVTNLIPNGS----FTEYIIGNGPLTTK-----------------------------------------
 ||| .||.|| .              .|..||. . |.|.      .|   . | ...                                         
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------GTPIFRLRIMLDSARGMEYLHAL------GLMHRDFKPLNILIDENER-----------GVLCDFG---
                                |.  .| .... |.||||||..      .. |||    |.|..|| .             ..|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LSRPF----SGKKSGDLGTMQ-------------------------WIAPELLQHGV--------QYDESVDVYAFGITLWVIAT--SKNPYTGM
     |.|         .... ||.                          | ||| |...|         . .  ||..||...| | |   . .| ||
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

RQ---------MQYANLVISE-------------NLRPTPPDDQPP-------------EFIKL-MQRCWDSNPKKRPTFREIRQIL
            .  ... ..              .|. .|.. |.             |.. . ||.||. .|..||||..... |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase 83996.m00266.AA Pkinase_Tyr 192-444 29 8.7e-48 162.46 Pfam 1-270 (270) Show / Hide
Range on Protein: 192-444
Range on HMM: 1-270/270
Sequence Identity: 29% (81 aa)

TIIKENIGSGGYASVHLARLK----STNELVAVKEMKASQLYARR---IIFMKREIDALMKL-NHPNTIRLIGVTV--TPP--FCIVTNLIPNGSFTEYI
 .. . .|.| . .|.....|    .|.  |||| .|    .  .   .  . ||.  ...| .||| .||.|| .    |   .||. . |.|.  .| 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

IGN---GPLTTKGTPIFRLRIMLDSARGMEYLHALGLMHRDFKPLNILIDENERGVLCDFGLSRPF-----S-GKKSGDLGTMQWIAPELLQHGVQYDES
  .   ..  |  .    | . .. |.|||||.. .. |||    |.|..||     |||||.|          |..|      | ||| ...|. . . 
RKHREDKQPLTMKD---LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTK

VDVYAFGITLWVIAT-SKNP-YTGMRQMQYANLVISENLRPTPPDDQPPEFIKLMQRCWDSNPKKRPTFREIRQIL
 ||..||...| | |  . | | ||   .  ...  .. |  .|.. |.|  .||..||. .|..||||.||...|
SDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase 83996.m00266.AA TyrKc 192-444 27 2e-47 164.77 SMART 1-280 (280) Show / Hide
Range on Protein: 192-444
Range on HMM: 1-280/280
Sequence Identity: 27% (80 aa)

TIIKENIGSGGYASVHLARLKSTNELVAVKEMKASQLYARRIIFMKREIDALMKL--NHPNTIRLIGVTVT--------PPFCIVTNLIPNGSFTEYIIG
   .. .|.| .  |.....|   . |||| .|..      .  . ||.  ..||  .||| .||.|| ..        .| .||. . |.|.  .|.  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

NGPLTTKGTPIFRLRIMLDSARGMEYLHALGLMHRDFKPLNILIDENERGVLCDFGLSRPFSGK-------KSGDL----GTMQ-----WIAPELLQHGV
..|     ..   | .... |.||||||  .. |||    |.|..|| .   .||||||    .       .  .     |.       | ||| ...|.
HRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

QYDESVDVYAFGITLW-VIATSKNPYTG-----MRQMQYANLVISENLRPTPPDD-------QPPEFIKLMQRCWDSNPKKRPTFREIRQIL
 . .  ||..||...| .    . || |     |   .  ..| . . .| ||.|        |.|  ..|..||. .|..||||.||....
-FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase 83996.m00266.AA Dicty4-Unclassified 194-444 31 3e-47 159.86 In-house 3-263 (263) Show / Hide
Range on Protein: 194-444
Range on HMM: 3-263/263
Sequence Identity: 31% (84 aa)

IKENIGSGGYASVHLARLKSTNELVAVKEMKASQLYAR--RIIFMKREIDALMKLNHPNTIRLIGVTVTP-----PFCIVTNLIPNGSFTEYII-----G
|   || |  . ||    |  .  |||| .   .  .|   |   |.|.. |  . ||| ... |  . |      .|||. ... |   | |       
IDQFIGKGHFSKVHKGNWKGKD--VAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQ

NGPLTTKGTPIFRLRIMLDSARGMEYLHALGLMHRDFKPLNILIDENERGVLCDFGLSRPFSGKKS-GDLG-TMQWIAPELLQHGVQYDESVDVYAFGIT
. |.    | |  ... .| |.|| .||   . ||| |  |||.| .      |||.||  .        . |  | .|| | |   |    ||| ... 
QQPIKLDDTLI--IKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHES-YNQKSDVYSYAMM

LWVIATSKNPYTGMR-QMQYANLVISENLRPTPPDDQPPEFIKLMQRCWDSNPKKRPTFREIRQIL
|.  ||   || .    |  | .| .  |||  ||  .. . ||   ||   |.||||. .| | |
LYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL

Kinase 83996.m00266.AA TKL-ciliate2 193-445 35 5.1e-44 144.52 In-house 2-273 (273) Show / Hide
Range on Protein: 193-445
Range on HMM: 2-273/273
Sequence Identity: 35% (99 aa)

IIKENIGSGGYASVHLARLKSTNELVAVKEMKASQLYARRIIFMKREIDALMKLNHPNTIRLIGV-TVTPPFCIVTNLIPNGSFTEYIIG-NGPLTTKGT
 |.. |  |||  .  |. . .   ||||  |      ..|     | .|.  | ||| .  .|  |  | |||.      ||    .   . .||    
EIQNKITEGGYGIIYKAKWREI--VVAVKKFKMDHDNQQQIRDFVNECHAMEALRHPNIVMFLGACTKIPNFCIIMEYCQRGSLWSLLQNQDVRLTWED-

PIFRLRIMLDSARGMEYLHALG--LMHRDFK--------------------PLNILIDENERGVLCDFGLSR--PFSGKKSGDLGTMQWIAPELLQHGVQ
   | || || |||. |||.    ..||| |                     ||.|.|.| |  | |||  |  |        .|| ||.||| ..  . 
---RRRIALDIARGVHYLHSSNPPIIHRDLKRQIKHKEKNLINIITLIKINSLNVLVDDNFRCKLTDFGWTRVKPQDNYMTNKIGTYQWMAPEVIKAFY-

YDESVDVYAFGITLWVIATSKNPYTGMRQMQYANLVISENLRPTPPDDQPPEFIKLMQRCWDSNPKKRPTFREIRQILE
| |  ||....| || ||    || ...    |  |. .||||| | . ||.|  ||||||| |   ||.| || . ||
YTEKADVFSYSIILWEIASREPPYRNKKGDVVAEKVMCNNLRPTIPKNCPPQFADLMQRCWDNNQNLRPSFNEIIKELE

Kinase 83996.m00266.AA STE 192-439 19 1.5e-41 144.36 In-house 1-350 (359) Show / Hide
Range on Protein: 192-439
Range on HMM: 1-350/359
Sequence Identity: 19% (71 aa)

TIIKENIGSGGYASVHLARLK------STNEL---------VAVKEMK---------------ASQLYARRIIFMKREIDALMKLN--HPNTIRLIGVTV
  . | ||.|.. .|..|. .      .|.|.         .|.|.|.                ..     .   ..||. ..|.|  ||| .. .|  .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TPP--------FCIVTNLIPNGSFTEYIIGNGPLTTKGT----------PIFRLRIMLDSARG-MEYLHALGLMHRDFKPLNILIDENERGVLCDFGLSR
            .|.  ....||... |  ..      .               .|  .  .| ..||| .. .||| || |||.       |||||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

PFSG-------------------KKSGDLGTMQWIAPELLQHG-----VQYDESVDVYAFGITLWVIATSKNPYTGMRQMQYANLVISEN--LR------
 ..                    |   . ||  | ||| .| .      .||...|.. .|.|..  || | |.  |  |.   . . ..   .      
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---PTPPDDQP----------------------PEFIKLMQRCWDSNPKKRPTFRE
   ..||  ..                      |||.  ...| . .|.||||  .
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ

Kinase 83996.m00266.AA DRK 294-446 38 3e-39 130.6 In-house 100-258 (258) Show / Hide
Range on Protein: 294-446
Range on HMM: 100-258/258
Sequence Identity: 38% (62 aa)

RLRIMLDSARGMEYLHALG--LMHRDFKPLNILIDENERGVLCDFGLSRPFSGKKSGDL-----GTMQWIAPELLQHGVQYDESVDVYAFGITLWVIATS
....|.| |.|| |||      .||| |  | |.||. .    |||||  |   |.        ||  |.||| |     | |  ||| |.| || ..| 
MKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQ-RYTEKADVYSFAIVLWECVTR

KNPYTGMRQMQYANLVISENLRPTPPDDQPPEFIKLMQRCWDSNPKKRPTFREIRQILES
. || ||  .|    |  . .||  |   || .|.||..||. .|  ||.. |. ..||.
QDPYFGMPTFQVVFSVGRHGMRPPMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA

Kinase 83996.m00266.AA DRK 193-274 30 0.000102 11.95 In-house 2-83 (258) Show / Hide
Range on Protein: 193-274
Range on HMM: 2-83/258
Sequence Identity: 30% (26 aa)

IIKENIGSGGYASVHLARLKSTNELVAVKEMKASQLY-ARRIIFMKREIDALMKLNHPNTIRLIGVTVTPP-FCIVTNLIPNGS
 |   || |.|. | .     |   |||| ...        .  ..|||. . .| ||| .  .|    ||  ||..  .| ||
KIGNRIGRGNYGEVFRGTWRGTQ--VAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGS

Kinase 83996.m00266.AA MLK 887-899 46 0.109957 1.78 In-house 279-291 (291) Show / Hide
Range on Protein: 887-899
Range on HMM: 279-291/291
Sequence Identity: 46% (6 aa)

HSRPPFQVILPYL
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HKRPSFRQIVQHL

Kinase 83996.m00266.AA TKL 887-899 53 0.246109 0.58 In-house 352-364 (364) Show / Hide
Range on Protein: 887-899
Range on HMM: 352-364/364
Sequence Identity: 53% (7 aa)

HSRPPFQVILPYL
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EKRPSFQEILKRL

Kinase 83996.m00266.AA DRK 889-901 46 0.270797 0.18 In-house 246-258 (258) Show / Hide
Range on Protein: 889-901
Range on HMM: 246-258/258
Sequence Identity: 46% (6 aa)

RPPFQVILPYLEI
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RPSMQECLERLEA