89386.m00149

Species: T.vaginalis
Alias: 89386.m00149, TvagK0076
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
89386.m00149.AA Protein None 350 None Fasta, JSON
89386.m00149.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of 89386.m00149.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 89386.m00149.AA AGC 9-261 22 6.5e-104 268.97 In-house 1-395 (395) Show / Hide
Range on Protein: 9-261
Range on HMM: 1-395/395
Sequence Identity: 22% (89 aa)

YAVKYCMGSGGFAQVYAAIHK------KTNCFVAIKMIP---KEIKDDENHKTRIQRE------------MEISASIQ----------HPFIID-LYEII
. .. . | |.| .|| . .|       |. . |.|..    | .....|   ....|             .| . ..          ||||.  |.   
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ESEKY--IYIVMEIIR---------NG-CLTNKLC---EKGKLCESTAKHIFAQ-------LATVLRFLHKEKNIAHRD-IKLENILLDDHNNIRIIDFG
.....  .|.||| .           |  |   |.    .|.. |..|....|.       ..  | .||....| ||| .|.||||||.. .|.. |||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSKFIQKDH---------------------------------------------------LTETLCG--SPQYASPEILMGQKYGFEADIWA--SGILLY
|.| . .|.                                                   .| |.||  .|.| .||||    ||...|.|.   |.|.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

TLVFGIFPFASENIT----------KLARAII------YKPPQFE----------GKISNELIDLITKLLVKNPKERIN----------IEEVCQHPWI
 ...|. || ..|            ..   |.       ....|            ..|.|. |||.|||.|.|..|.           .||. .||| 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF

Kinase 89386.m00149.AA CAMK 14-261 23 7.69999999999e-103 332.26 In-house 1-425 (425) Show / Hide
Range on Protein: 14-261
Range on HMM: 1-425/425
Sequence Identity: 23% (102 aa)

CMGSGGFAQVYAAIHKKTN------------CFVAIKMIPKE-IKDD------------------------ENHKTRIQREMEISAS-------IQHPFI
  |.|.|..|. .|||.|.              ||||.|.|. .||.                        .. . ...||.||  .       ..|| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IDLYEIIES-------------------EKYIYIVM---EIIRNGCL----TNKLCEK---------------GKLCESTAKHIFAQLATVLRFLHKEKN
| |||..|.                   .|..|.||   | . .|.|     ....|.               |...|. |...| |..  ....|. . 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN-

IAHRDIKLENILLDDH-----------------NNIRIIDFGLSKFIQK------------------------DHLTETLCGSPQYAS-PEILMG-----
|.|||.|.|||||||.                 ||| |||||.......                        ... .| ||.| |.. ||.| |     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------QKYGFEADIWASGILLYTLVFGIFPFASE-------------NITKLARAII---YK-PPQF------------EGKISNE--------LI
         . ||...|.|. |..||... | .|| ..             |. .| . |.   |  || .             ..||.|         .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLITKLLVKNPKERINIEEVCQHPWI
||| |.|...|..|..||.. .|||.
DLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase 89386.m00149.AA CAMKL 9-261 32 5.4e-101 323.06 In-house 1-297 (297) Show / Hide
Range on Protein: 9-261
Range on HMM: 1-297/297
Sequence Identity: 32% (98 aa)

YAVKYCMGSGGFAQVYAAIH-KKTNCFVAIKMIP--KEIKDDENHKT----------RIQREMEISASIQ---HPFIIDLYEIIESEKY------IYIVM
| .    | |.|..|  |.| . |.. ||||.|   |  .|. ..|           ||.||..|  ...   || || |||.|| ...      ||.||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EIIRNGC--LTNKLCEK----GKLCESTAKHIFAQLATVLRFLHKEKNIAHRDIKLENILLDDHN--NIRIIDFGLSKFIQK-----DHLTETLCGSPQY
| . .|   | ......    |.. |. |...| |.   . ..|. . |.|||||.||||||...  || |||||.| ....     ... .| |||| |
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHG-IVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

ASPEILMG--Q-KYGFEADIWASGILLYTLVFGIFPFASENI-------TKLARAIIYKPPQFEG---KISNELIDLITKLLVKNPKERINIEEVCQHPW
..|||. |  .  .|...|||. |..||..|.| .||  ...       . . . .| .   ..    ..| ...||| |.|..||..|..|... .|||
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW

I
 
M

Kinase 89386.m00149.AA S_TKc 9-261 31 3.8e-94 320.0 SMART 1-231 (231) Show / Hide
Range on Protein: 9-261
Range on HMM: 1-231/231
Sequence Identity: 31% (86 aa)

YAVKYCMGSGGFAQVYAAIHKKTNCFVAIKMIPKEIKDDENHKTRIQREMEISASIQHPFIIDLYEIIESEKYIYIVMEIIRN--GCLTNKLCEKGK---
| .    |.|.|..|| ..||||.  ||||.|.           .|.||..|  . .||.|. ||..... ...|.||| . .  | |   ....|.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LCESTAKHIFAQLATVLRFLHKEKNIAHRDIKLENILLDDHNNIRIIDFGLSKFIQKDHLTETLCGSPQYASPEILMGQKYGF-EADIWASGILLYT
   . | .|.....|..  | ..|.  .| |||.| ||||||.  .| |.||||....       |.||.| | .||.|   .||. ..|.|. |..|| 
RFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

LVFGIFPFASENITKLARAIIYKPPQFEGKISNELIDLITKLLVKNPKERINIEEVCQ-------HPWI
.. |  ||   .. .. . |           | |..|.| |.|.|.|..|. . |. |       |||.
MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 89386.m00149.AA Pkinase 9-261 30 3.7e-88 303.97 Pfam 1-293 (293) Show / Hide
Range on Protein: 9-261
Range on HMM: 1-293/293
Sequence Identity: 30% (89 aa)

YAVKYCMGSGGFAQVYAAIHKKTNCFVAIKMIPKEIKDDENHKTRIQ-REMEISASIQHPFIIDLYEIIESEKYIYIVMEIIRNG----CLTNKLC--EK
| .. . |||.|..|| ..||.|.. ||.| |.|. .... ..|..  .| .| ....||.|. ||.. |....||.|||  ..|     |   .   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GKL--CESTAKHIFAQLATVLRFLHKEKNIAHRDIKLENILLDDHNNI----RIIDFGLSKF--IQKDHLTETLCGSPQYASPEILM-GQKYGFEADIWA
|..   | ..|... |..  | ..|. ..| |||.|.||||.|....|    .|.||||.|.  . ... . |.||.| |..||... ||.|| ..|.|.
GCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

SGILLYTLVFGIFPFASE------NITKLARAIIYKPPQFEGKIS---------------------NELIDLITKLLVKNPKERINIEEVCQHPWI
 |..|| ...| .|| ..      .  .. . | ..|. |.   .                      |..|.|...| |.||.|...|...||||.
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 89386.m00149.AA Ciliate-E2-Unclassified 9-261 28 8.8e-86 291.29 In-house 1-352 (352) Show / Hide
Range on Protein: 9-261
Range on HMM: 1-352/352
Sequence Identity: 28% (102 aa)

YAVKYCMGSGGFAQVYAAIHKKTNCFV-----AIKMIPKEIKDDENHKTRIQREMEISASIQ-------------------HPFIIDLYEIIESEKYIYI
| . .. |.|||..|| ..|||.. ..     ..|.. .  |  .| . .| .||..  ...                   ||||. .... .....|||
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VMEIIRNGCLTNKLCEKGK-----------------LCESTAK-----HIFAQLATVLRFLHKEKNIAHRDIKLENILLDDHN---NIRIIDFGLSKFIQ
||| ...| | . .....|                 . |  ||     ..|||.   | .||...|| |||||.||||.|. .   .|.|||||.||..|
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

----------------KDHLTETLCGSPQYA----SPEILMGQKYG----FEADIWASGILLYTLVFGIFPFASENITK----------------LARAI
                |.... | ||.|.|     .||.|.||.|.    ...|||. |..|| ..|| .|| ..| ..                | . |
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

IYKPPQFEG--------KISNELIDLIT----KLLVKNPKERINIEEVCQHPWI
. |..||          ..|.| .|.|.    |.|.|||..||..|....|||.
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 89386.m00149.AA MARK 9-261 37 5.4e-85 277.78 In-house 1-262 (262) Show / Hide
Range on Protein: 9-261
Range on HMM: 1-262/262
Sequence Identity: 37% (101 aa)

YAVKYCMGSGGFAQVYAAIHKKTNCFVAIKMIPKEIKDDENHKTRIQREMEISASIQHPFIIDLYEIIE--SEKY-IYIVMEIIRNGCLTNKLCEK--GK
| .. . | |..|.|. |.||.|.  ||||...|. ..| . .  ..||.||  ...|| || |...||   |.  ||..|| . .| | . . ..  |.
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LCESTAKHIFAQLATVLRFLHKEKNIAHRDIKLENILLDDHN--NIRIIDFGLSKFIQKDHLTETLCGSPQYASPEILMGQKYG-FEADIWASGILLYTL
|.|. |..|| |.   . ..|.   |.|||||.||||.|...  || |||||.|  |. . . .| ||.| |..|||. ...|  ...|||. |..||..
LHEEEARRIFRQIVSAVNYCHSKN-IVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM

VFGIFPFASEN--ITKLARAII---YKPPQFEGKISNELIDLITKLLVKNPKERINIEEVCQHPWI
| | |||   .  . .| . |    |. | .   .| |. .|| .||. ||.||. |||. .|||.
VCGYFPFDGDTQDYKELYKKILRGKYDIPCH---VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase 89386.m00149.AA AMPK 9-261 39 4.8e-83 246.4 In-house 1-254 (254) Show / Hide
Range on Protein: 9-261
Range on HMM: 1-254/254
Sequence Identity: 39% (101 aa)

YAVKYCMGSGGFAQVYAAIHKKTNCFVAIKMIPKEIKDDENHKTRIQREMEISASIQHPFIIDLYEII-ESEKYIYIVMEIIRNGCLTNKLCEKGKLCES
| ..  .| | |  |  ..|. |.  |||| . |.   |.  . ||||| .|  .. || || |||.| |... |..||| . .| |    . .|.| | 
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

TAKHIFAQLATVLRFLHKEKNIAHRDIKLENILLDDHNNIRIIDFGLSKFIQKDHLTETLCGSPQYASPEILMGQKY-GFEADIWASGILLYTLVFGIFP
 |.  |.|    .  .|.  .|.||| |.||.|||...|| | |||||.  ..  .  | |||| ||.||.  |..| | | ||| .|. || .. |  |
EACRFFQQIISGVEYCHR-HMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLP

FASENITKLARAII---YKPPQFEGKISNELIDLITKLLVKNPKERINIEEVCQHPWI
|  ||...| . |.   |. |.|   .|.|  ||| ..| ..| .||.|... .||| 
FDDENTPTLYKKIKNGEYYIPKF---LSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF

Kinase 89386.m00149.AA Ciliate-E2 9-261 25 1.5e-82 280.53 In-house 1-365 (365) Show / Hide
Range on Protein: 9-261
Range on HMM: 1-365/365
Sequence Identity: 25% (95 aa)

YAVKYCMGSGGFAQVYAAIHKKTNC-----------------------FVAIKMIPKEIKDDENHKTRIQREMEISA-----------SIQHPFIIDLYE
| .  . |.|.|..|| . ..|...                       ..|.|.. |  .   . . .| ||...             ...||.|| .||
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINC-FYKKINEKNILEQLNHPNIIKMYE

IIE--SEKYIYIVMEIIRNGCLTNKLCEKGKLC-----------ESTAKHIFAQLAT---------------VLRFLHKEKNIAHRDIKLENILLDDHNN
  .  ....||.||| .  | |   . .. | .           |  .|.|..|..                 |..||...|| |||||.||||.     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

IRIIDFGLSKFIQKD--------------------------------HLTETLCGSPQYASPEILMGQK---------YGFEADIWASGILLYTLVFGIF
| ||||||||....|                                ... |.||.| | .||||.|.|         |....|||. |..|| ..|| .
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFASENITKLARAIIYKPPQFE------------------GKISNELIDLITK----LLVKNPKERIN-IEEVCQHPWI
||         . |. .. .|                    |.|.| .||| |    .|.|.|..||. .|.. .|||.
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 89386.m00149.AA QIK 9-261 36 5.1e-80 272.16 In-house 1-272 (272) Show / Hide
Range on Protein: 9-261
Range on HMM: 1-272/272
Sequence Identity: 36% (101 aa)

YAVKYCMGSGGFAQVYAAIHKKTNCFVAIKMIPKEIKDDENHKTRIQREMEISASIQHPFIIDLYEIIESEKYIYIVMEIIRNGCLTNKLCEKGK-----
| .   .| | || |  | |. |   |||| | |.  | || . .. || .|  ...||.|| ||...|.....|||.|   || .   ||..|.     
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQ-KCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------LCESTAKHIFAQLATVLRFLHKEKNIAHRDIKLENILLDDHNNIRIIDFGLSKFIQKDHLTETLCGSPQYASPEILMGQKY-GFE
               . |. |. .| |...   ..|| .||.|||.| ||||||   || |.|||.| . ....| .| |||| || ||.. |..| | .
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHK-RNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPK

ADIWASGILLYTLVFGIFPFASENITKLARAII---YKPPQFEGKISNELIDLITKLLVKNPKERINIEEVCQHPWI
.|||  |..|| || | .|| ......| . ..   .. | |   .| .. .|| . || .|. |..|. .|||.|.
VDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFF---MSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM

Kinase 89386.m00149.AA ULK 9-261 29 1.4e-76 260.73 In-house 1-329 (329) Show / Hide
Range on Protein: 9-261
Range on HMM: 1-329/329
Sequence Identity: 29% (98 aa)

YAVKYCMGSGGFAQVYAAIHKKT----NCFVAIKMIPKEIKDDENHKTR-------IQREMEISASI----QHPF----IIDLYEIIESE--KYIYIVME
| .. | |.| |..|| ...|||    |  ||.|||.|. .. .|.          ...| .|   .    .|..    |. ||.. |.   ..|||.||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

IIRNGCLTNKLCEKGKLCEST----------AKHIFAQLATVLRFLHKEKNIAHRDIKLENILLDDHNN------------IRIIDFGLSKFIQKD----
    | | . . ...|| |.|          |...| |..  ...||| .|| |||||..|||.....             . | |||..|....|    
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHK-HNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQ

--HLTET----LCGSPQYASPEILM----GQKYG-FEADIWASGILLYTLVFGIFP----FASEN---ITKLARA-------IIYKPPQFE-----GKIS
   .| .    |||.| | .|.||.    ...|. ...|||  |...| ...|  |    | ...   |.|| .        |  .|.||.      .||
QMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

NELIDLITKLLVKNPKERINIEEVCQHPWI
.|..||| ..|....|.||..||. .|||.
PECKDLIRRMLQYDEKDRISWEELFNHPWF

Kinase 89386.m00149.AA ULK 9-261 29 4.9e-76 258.92 In-house 1-324 (324) Show / Hide
Range on Protein: 9-261
Range on HMM: 1-324/324
Sequence Identity: 29% (97 aa)

YAVKYCMGSGGFA-QVYAAIHKKT---NCFVAIKMIPKE-IKDDENH------KTRIQREMEISASIQ---HPF--IIDLYEIIESE--KYIYIVMEIIR
| .. | |.| |. .|| ...|||   | .||.|||.|  .....|       .  ...| .|   .    ||.  |. ||.. |.   ..|||.||   
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGCLTNKLCEKGKLCEST----------AKHIFAQLATVLRFLHKEKNIAHRDIKLENILLDDHNN------------IRIIDFGLSKFIQKDHLTETLC
 | | . . ...|| | |          |...| |..  ...||| .|| |||||..|||. ...             . | |||..|..... . ...|
GGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHK-HNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMC

----------GSPQYASPEILM----GQKYG-FEADIWASGILLYTLVFGIFP----FASEN--ITKLARA-------IIYKPPQFE-----GKISNELI
          |.| | .|.||.    ...|. ...|||  |...| ...|  |    | ...  | || .        | ..| ||       |||.|..
QTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECK

DLITKLLVKNPKERINIEEVCQHPWI
||| ..|....|.||..||. .|||.
DLIRRMLQYDEKDRISWEEIFNHPWF

Kinase 89386.m00149.AA Pkinase_Tyr 16-161 32 1.3e-15 53.54 Pfam 8-164 (270) Show / Hide
Range on Protein: 16-161
Range on HMM: 8-164/270
Sequence Identity: 32% (51 aa)

GSGGFAQVYAAIHK----KTNCFVAIKMIPKEIKDDEN-HKTRIQREMEISASI-QHPFIIDLYEIIE-SEKY--IYIVMEIIRNGCLTNKLCE----KG
|.| | .|| .. |    .|.. ||.||. ||  ..|.  .    ||..|  .. .|| |. || ..   ..   ||||||   .|.| . | .    |.
GEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQ

KLCESTAKHIFAQLATVLRFLHKEKNIAHRDIKLENILLDDHNNIRIIDFGLSKFIQKD
.|. ..  .. .| |  . .|. .||. |||.   |.|... | ..| ||||.. |..|
PLTMKDLLQMCWQIAKGMEYLE-SKNCIHRDLAARNCLVTENNVVKICDFGLARDIYND

Kinase 89386.m00149.AA TyrKc 16-261 21 4.3e-15 21.4 SMART 8-280 (280) Show / Hide
Range on Protein: 16-261
Range on HMM: 8-280/280
Sequence Identity: 21% (61 aa)

GSGGFAQVYAAIHKKTNCFVAIKMIPKEIKDDENHKTRIQREMEISASI--QHPFIIDLYEIIESE-------KYIYIVMEIIRNGCLTNKLCEKGK-LC
|.| | .|| .. |     ||.||. ..       .  . ||..|  ..  .|| |. || .. ..       . ..||||   .|.| . | .... ||
GEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLC

ESTAKHIFAQLATVLRFLHKEKNIAHRDIKLENILLDDHNNIRIIDFGLSKFIQKD----HLTETLC-----GSPQ-----YASPEILMGQKYGFEADIW
 ..  ..  | |   ..||.  |. |||.   |.|... . ..| |||||..|  |      ...       |.         .|| ..  |. .. |.|
MKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVW

ASGILLY-TLVFGIFPFAS-----ENITKLARAIIYK--PPQFEG-------KISNELIDLITKLLVKNPKERINIEEVCQHPWI
. |....  . .|  |         . . . . .     .|| .          . |. .....    .|..| . .|.  |  .
SFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase 89386.m00149.AA Pkinase_Tyr 175-198 29 5.911139 0.47 Pfam 182-205 (270) Show / Hide
Range on Protein: 175-198
Range on HMM: 182-205/270
Sequence Identity: 29% (7 aa)

SPEILMGQKYGFEADIWASGILLY
.|| ..  |.  . |.|. |.|..
APECINYGKFTTKSDVWSFGVLMW