Gene 81529.m00415 (T.vaginalis)

81529.m00415

Species: T.vaginalis
Alias: 81529.m00415, TvagK0944
External Links:
Annotation:

Classification

Group: Other
Family: Other-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
81529.m00415.AA Protein None 451 None Fasta, JSON
81529.m00415.kin_dom Protein Kinase Domain None 111 None Fasta, JSON

Protein domain

Protein domains of 81529.m00415.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 81529.m00415.AA Ciliate-E2-Unclassified 176-294 23 5.6e-22 73.03 In-house 102-268 (352) Show / Hide 
Range on Protein: 176-294
Range on HMM: 102-268/352
Sequence Identity: 23% (40 aa)

YCQNGTLTSYVINHPN-----------------LTNTQLI-----EIFINTCNLVMKIHSKK-ILIRDIKPDNILIDDKL---IPHISDFDVA-------
||..|.|  |  . ..                 .|  | .      .|   ..   ..|.|. |. |||||.|||.|..     . |.||  .       
YCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNN

-----------LIDQMESTEYVGTKMFM----APEVKKNKEGTCLYG----VKSEIYSLGCVLSWMFTRLY
            ..|....  .|| ..|    |||| ....    |.     |. |.|||..| .| .  |
NCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQN----YDHSKAYKCDIWSLGVILYEMLFGYY
Kinase 81529.m00415.AA Ciliate-E2 176-291 21 7.5e-19 61.33 In-house 115-291 (365) Show / Hide 
Range on Protein: 176-291
Range on HMM: 115-291/365
Sequence Identity: 21% (40 aa)

YCQNGTLTSYVINH-----------PNLTNTQLIEIFINTCN--------------LVMK-IHSKK-ILIRDIKPDNILIDDKLIPHISDFDVALIDQME
||| |.| .| .|.            ..|  . ..|.   ..              | .. .|||. |. |||||.|||.     . |.||  . . . .
YCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDD

STE----------------------------------YVGTKMFMAPEVKKNKE-----GTCLYGVKSEIYSLGCVLSWMFT
. .                                  ..|| ..||||. ..|.     .   |. |. |.|||..| .| .
NQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF
Kinase 81529.m00415.AA TKL 212-333 18 2.6e-18 62.56 In-house 149-364 (364) Show / Hide 
Range on Protein: 212-333
Range on HMM: 149-364/364
Sequence Identity: 18% (41 aa)

HS--------KKILIRDIKPDNILIDDKLI--------------PHISDFDVAL-IDQMESTEY---------------------VGTKMFMAPEVKKNK
||        ..|. ||.|..|||.|...               . |.||  .  ..|... .                      .||. .||||| ...
HSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQ

EGTC------------LYGVKSEIYSLGCVLSWMFT--RLYANFAHFTPL------------------------------------VPPSIQKLALQMLS
. ..             |  |. .|| | ||  ..|  | |... .....                                    .|||. ||. .  .
MNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWD

EKPEDRPTLDTVVRQL
..||.||. .... .|
HDPEKRPSFQEILKRL
Kinase 81529.m00415.AA Pkinase 176-286 29 5.2e-17 61.22 Pfam 81-202 (293) Show / Hide 
Range on Protein: 176-286
Range on HMM: 81-202/293
Sequence Identity: 29% (38 aa)

YCQNG----TLTSYVI--NHPNL--TNTQLIEIFINTCNLVMKIHSKKILIRDIKPDNILIDDKLIP----HISDFDVA----LIDQMESTEYVGTKMFM
||..|     | .|.   .| ..  .  ... ..  ..  .  .||..|. ||.||.|||||..  .    .|.|| .|    .  .   | ..||  .|
YCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYM

APEVKKNKEGTCLYGVKSEIYSLGCVL
|||| .   |   || |. ..|.||.|
APEVIR---GGQYYGPKVDMWSCGCIL
Kinase 81529.m00415.AA AGC 211-286 18 1.2e-16 38.13 In-house 169-295 (395) Show / Hide 
Range on Protein: 211-286
Range on HMM: 169-295/395
Sequence Identity: 18% (25 aa)

IHS-KKILIRD-IKPDNILIDDKLIPHISDFDVALIDQME-----------------------------------------------------STEYVG-
.|| ..|  || .||.|||.|..   ...||  . .  ..                                                      .  .| 
LHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGP

-TKMFMAPEVKKNKEGTCLYGVKSEIYS--LGCVL
 |  .||||.         ||    ..|  |||..
CTPEYMAPEIL--------YGKACDWWSFGLGCLM
Kinase 81529.m00415.AA Ciliate-E3 171-290 32 1.9e-16 48.05 In-house 80-202 (202) Show / Hide 
Range on Protein: 171-290
Range on HMM: 80-202/202
Sequence Identity: 32% (41 aa)

FVSSLYCQNGTLTSYVINHPNLTNTQLIEIFINTCNLVMKIHSKKILIRDIKPDNILIDDKL---IPHISDFDVA--LIDQM--ESTEYVGTKMFMA-PE
|. . || || |. |.    |.|   ...|.|.    .. ||.|.|   ||||||||.|  .   |  |.||  .  |       .| | |.  |.| ||
FIVQEYCSNGDLYHYIK-QQNKTQNIIYDICIQIIQGMIAIHEKNIIHSDIKPDNILVDKNNNQLIIKICDFGESKQLRKNKGHTHTQYQGWTPFYAAPE

VKKNKEGTCLYGVKSEIYSLGCVLSWMF
. ..     .    | .||.| |.  . 
QNDQQ----QISKESDYYSVGAVFCQLC
Kinase 81529.m00415.AA STE 176-286 23 7.4e-15 49.01 In-house 118-258 (359) Show / Hide 
Range on Protein: 176-286
Range on HMM: 118-258/359
Sequence Identity: 23% (35 aa)

YCQNGTLTSYVINH----PNLT----------NTQLIEIFINTCNL-VMKIHSKKILIRDIKPDNILIDDKLIPHISDFDVALIDQM-------------
|. .|.|.. . .      .|.           .|.. |   ..      .||..|  |||||.|||.       ..|| |. . .              
YMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDC

------ESTEYVGTKMFMAPEVKKNKEGTCL---YGVKSEIYSLGCVL
      ...  |||  .||||| .. ...     |..|. |.||||..
IETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDTKCDIWSLGCTI
Kinase 81529.m00415.AA Ciliate-E1 191-280 23 9.2e-15 44.86 In-house 105-202 (202) Show / Hide 
Range on Protein: 191-280
Range on HMM: 105-202/202
Sequence Identity: 23% (23 aa)

NLTNTQLIEIFINTCNLVMKIHSKKILIRDIKPDNILIDDKLIPHISDFDVALIDQMESTEYV---GTKMFMAPEVKKN-----KEGTCLYGVKSEIY
..| .|...|...    .  .|...|..|||||.||||... .  ..|| .... . ......   | .  ..|. ..|      . .  .. ||.||
QFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKSDIY
Kinase 81529.m00415.AA C8 199-286 32 2.8e-13 42.52 In-house 127-226 (226) Show / Hide 
Range on Protein: 199-286
Range on HMM: 127-226/226
Sequence Identity: 32% (32 aa)

EIFINTCNLVMKIHSKKILIRDIKPDNIL--IDDKLIPHI--SDFDVALI-----DQMESTEY--VGTKMFMAPEVKKN-KEGTCLYGVKSEIYSLGCVL
.| |     |  ||.|.|..|||||.|.|   | . .. |  .||..|       ....| ..  .||. ..|||. |  ..    |  .| ..|.| ||
IIAIQMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFAPEIEKKQDNQYKQYRIQSDLFSVGLVL
Kinase 81529.m00415.AA ULK 176-286 26 3e-13 42.67 In-house 101-246 (329) Show / Hide 
Range on Protein: 176-286
Range on HMM: 101-246/329
Sequence Identity: 26% (39 aa)

YCQNGTLTSYVINHPN----------LTNTQLIEIFINTCNLVMKIHSKKILIRDIKPDNILIDDKL------------IPHISDFDVALI---D---QM
||. |.| .|  .. .          |.  . |..|.  .|  . .|...|  |||||.||||...             .  |.||  |     |   | 
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

ESTEYV------GTKMFMAPEVKKNKEGTCLYG-VKSEIYSLGCVL
  . .|      || ..|||.. ... . . |.  |. |.||||..
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIF
Kinase 81529.m00415.AA Ciliate-C8 211-286 26 7.2e-13 42.74 In-house 135-238 (238) Show / Hide 
Range on Protein: 211-286
Range on HMM: 135-238/238
Sequence Identity: 26% (28 aa)

IHSKKILIRDIKPDNIL-IDD-KLIPHI----------SDFDVALIDQME---------STEY-----VGTKMFMAPEVKKN--KEGTCLYGVKSEIYSL
.| . |. |||||.|.| ..| . .| |           .|  .| .. .         . .|     .|.  ..|||| |.  .    ..  ||..||.
LHCFNIMHRDIKPHNFLVCFDQQYQPTIKLCDFKKQCDFGFASQLPKNKSHYHSKKFKGTDQYIEMYFCGNWGYFAPEVEKKQSRIQSDIFSKKSDSYSV

GCVL
| ||
GLVL
S_TKc 81529.m00415.AA S_TKc 112-336 21 2.7e-12 3.4 SMART 1-231 (231) Show / Hide 
Range on Protein: 112-336
Range on HMM: 1-231/231
Sequence Identity: 21% (56 aa)

PEGFEAIGYGDHSVVIKPLDNE---KYVFKYMRCDNPQDRLIKERLGET-------NYYPSILTIPHTKFVSSLYCQN--GTLTSYVINHPN------LT
 |  . || |  ..| |  ...   ..  | ..     .....|.           ..| .. .  |  .|   || .  |.| .|  ...       ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKKHHPNIVKLYDVFQD-DHLYMVME-YCDGDLGDLFDYIKKRGRHGLRFPFP

NTQLIEIFINTCNLVMKIHSKKILIRDIKPDNILIDDKLIPHISDFDVALIDQMESTEYVGTKMFMAPEVKKNKEGTCLYGV-KSEIYSLGCVLSWMFT-
  .   ..  .|. .  .||..|. ||.||.|||.|.     |.|| .| .     | ..||  .|||||         ||  |. ..|.||.|  |.. 
E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL-------GYGKCKCDWWSCGCILYEMLCG

-----RLYANFAHFTPLVPPSIQKLALQMLSEKPEDRPTLDTVVR------QLNIV
      ... | .     .|.   .  ..|   ||.|||   . .      .   .
YPPFPQMQMMFKKIG---SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
TyrKc 81529.m00415.AA TyrKc 115-333 16 4e-06 -124.4 SMART 16-280 (280) Show / Hide 
Range on Protein: 115-333
Range on HMM: 16-280/280
Sequence Identity: 16% (46 aa)

FEAIGYGDHSVVIKPLDNEKYVFKYMRCDNPQDRLIKERLGETNYY---PSIL------TIP-------HTKFVSSLYCQNGTLTSYVINHPN-LTNTQL
.... .    | .| | ...           .  ...|    ....   | |.      | .       .  ..   |. .| | .|  .| . |.. .|
YKGTWK--IQVAVKMLKEDA-----------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMKDL

IEIFINTCNLVMKIHSKKILIRDIKPDNILIDDKLIPHISDFDVALIDQMEST-------EYVGT-----KMF------MAPEVKKNKEGTCLYGVKS--
... .  ..    .|||..  ||.   |.|......  ||||   |    ..        .|  .     . .      ||||.      .. .  ||  
LSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDF--GLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI----NYGKFTTKSDV

--------EIYSLGCVLS-------WMFTRLYANFAHF----TPLV---------PPSIQKLALQMLSEKPEDRPTLDTVVRQL
        ||...|              ......  .      |           |. . .. .|   |.||||||  ......
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 81529.m00415.AA Pkinase 300-333 16 0.613698 4.4 Pfam 259-293 (293) Show / Hide 
Range on Protein: 300-333
Range on HMM: 259-293/293
Sequence Identity: 16% (6 aa)

FTPLVPPSIQKLALQMLSEKPEDRPTLDTVVRQ--L
| ...... ...   .|  .|..||| . ..    .
F-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF