Gene 83945.m00092 (T.vaginalis)

83945.m00092

Species: T.vaginalis
Alias: TvagK0743, 83945.m00092
External Links:
Annotation:

Classification

Group: Other
Family: CAMKK

Sequence

Name Sequence Type Origin Length Description Download
83945.m00092.AA Protein None 367 None Fasta, JSON
83945.m00092.kin_dom Protein Kinase Domain None 272 None Fasta, JSON

Protein domain

Protein domains of 83945.m00092.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 83945.m00092.AA CAMK 97-363 19 9.7e-72 230.22 In-house 1-425 (425) Show / Hide 
Range on Protein: 97-363
Range on HMM: 1-425/425
Sequence Identity: 19% (85 aa)

HIGHGSASDVFLVKNQETG------------IMYAAKVYDQDYL-------------YRMSIGES------VPPIEKVSREIQLMSE-------INHPNI
 .|.|| . |.|... .|.              .|.|..| . |              ..| . .          ..| |||..|.        ..||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VPLIEILDD-----------QPTH-------SLIIIL---PFAEKGSL----------SKS----------SWKADPLPEAEAKNTFRQIASALQYLHSL
. |.|. .|             ..        .....    ... | |           ..            .   ..|.||.  ||||.||..|.||.
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSH

DIIHRDLKPENILCFAD-----------------GHSAISDFSVSLKLED-----------------------PNEMLEDTEGTPVFYS-PEQCSG----
.|.||||||||||.  .                 .   |.||  . |...                       .......  ||| . . ||  .|    
NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

---------EPYLGKPADCWAFGIVLYLMIFGKLPFFEADDEEIYR-----THFFHISQVISTEELTYPDTS----------------------NLSNEL
         .|| |...|.|. |..|| |  |..|| . .|.||.      ..   . . | . . ..|.                        ..| | 
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC

VDLFHHILDRNPATRYNMDQICSHKWF
 ||  ..| ..|  |.. .|. .|.|.
KDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 83945.m00092.AA CAMKK 92-363 24 3.9e-68 215.21 In-house 1-396 (396) Show / Hide 
Range on Protein: 92-363
Range on HMM: 1-396/396
Sequence Identity: 24% (99 aa)

YEFQQHIGHGSASDVFLVKNQET-GIMYAAKVYDQ----DYLYR--MSI-------------GESVPP--IEKVSREIQLMSEINHPNIVPLIEILDDQP
||... ||.|.   | |..| .. .  || |...     . | .  ...             ||. ..  .. | .||  |  .|||||| |.|..||. 
YELMKEIGQGQFGKVKLAYNEYDTQKHYAIKIFNKKYVFKKLKKKQQFYRDPPKRMTNMNQNGEMQMMNPFDCVYQEIAIMKKCNHPNIVKLYEVIDDPQ

THSLIII-LPFAEKGSLSKSS-WKA-----D-------------P------LPEAE---------------------AKNTFRQIASALQYLH-SLD---
  .. .. . ..|.|.. .   ||      .             .      . | .                     |.  ||... .|.||| .     
NDKIYMVQMEYCERGQIMWWPYWKQDYQPNWPYQYTELYSNRQYQNKDFSIMSEQQSISEFINQVVKQDQYFIHEDYAWKYFRDCIKGLEYLHNYQKACS

----------------IIHRDLKPENILCFADG---HSAISDFSVSLKLEDPNEMLED-----------TEGTPVFYSPEQCSGEP--------------
                |||||.||.|||.  .|   |  |.||.||...|. .. | .           |.||| |  ||.|| |               
YIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVSHIFEGQDQTLSNCESCFQRELNKTAGTPAFMAPELCSKENQKENYNGYKYRFRF

-YLGKPADCWAFGIVLYLMIFGKLPFFEADDEEIYRTHFFHISQVISTEELTYPD-----------TSNLSNELVDLFHHILDRNPATRYNMDQICSHKW
 | ||.|| || |. || ..|||.||.. .....     .|.   |  .....|.            ...|..|.||.   |. || .| . .|| .|.|
IYCGKAADIWALGVTLYCFVFGKCPFWHNNLMQL-----HHNYMKIKNDPIKFPENKEMLNNVSIYCPEISEDLKDLIKRMLEKNPTKRITIPQIKVHPW

F
.
V
Kinase 83945.m00092.AA CAMKL 92-363 28 4.5e-68 216.28 In-house 1-297 (297) Show / Hide 
Range on Protein: 92-363
Range on HMM: 1-297/297
Sequence Identity: 28% (86 aa)

YEFQQHIGHGSASDVFLVKN-QETGIMYAAKVYDQDYLYRMSIGESVPP-------IEKVSREIQLMSEIN---HPNIVPLIEILDDQPT----HSLIII
|.. . .|.|| . | | .. . ||...| |..| . .    . .. ..         .. ||||.|. .|   ||||. | |..... .      . ..
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

LPFAEKGS------LSKSSWKADPLPEAEAKNTFRQIASALQYLHSLDIIHRDLKPENILCFADG--HSAISDFSVSLKLED----PNEMLEDTEGTPVF
.  .. |.      . |   . ...|| ||.  |||| ||..|.||..|.|||.||||||   .|     |.||  | . ..    |...|.   |.| .
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

YSPEQCSG--EPYLGKPADCWAFGIVLYLMIFGKLPFFEADDEEIYRTHFFHISQVISTEELTYPDTSNLSNELVDLFHHILDRNPATRYNMDQICSHKW
 .|| ..|  .|| |...|.|. |..|| |..|.||| ......   ...      | .    .|  . .| .. || ...| .||  |....|| .|.|
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW

F
.
M
S_TKc 83945.m00092.AA S_TKc 92-363 26 1.4e-66 228.39 SMART 1-231 (231) Show / Hide 
Range on Protein: 92-363
Range on HMM: 1-231/231
Sequence Identity: 26% (77 aa)

YEFQQHIGHGSASDVFLVKNQETGIMYAAKVYDQDYLYRMSIGESVPPIEKVSREIQLMSEINHPNIVPLIEILDDQPTHSLIIILPFAEK--GSLSKSS
||. ..||.|. . |..... .||  .| |. .                |.. ||||.... .||||| |... .|   ..| ... ...   |.| .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYI

WKADP------LPEAEAKNTFRQIASALQYLHSLDIIHRDLKPENILCFADGHSAISDFSVSLKLEDPNEMLEDTEGTPVFYSPEQCSGEPYLGKPADCW
 |  .      .|| .|.  ..||..||.|.||. ||||||||||||.    |  |.|| .. .|           ||| . .|| .   .| ....| |
KKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWW

AFGIVLYLMIFGKLPFFEADDEEIYRTHFFHISQVISTEELTYPDTSNLSNELVDLFHHILDRNPATRYNMDQICS-------HKWF
..|..|| |. |. ||   .......                       | |. |.  ..|...|. |.   ..         | ||
SCGCILYEMLCGYPPFP--QMQMMFKKIG--------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 83945.m00092.AA Pkinase 92-363 27 8.7e-59 206.42 Pfam 1-293 (293) Show / Hide 
Range on Protein: 92-363
Range on HMM: 1-293/293
Sequence Identity: 27% (84 aa)

YEFQQHIGHGSASDVFLVKNQETGIMYAAKVYDQDYLYRMS------IGESVPPIEKVSREIQLMSEINHPNIVPLIEILDDQPTHSLIIILPFAEKG--
|.. . || || . |.. ... ||...| |. . .            .           .|||.| ..|||||| |...  | ..|   ......|.|  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-----------SEIQIMKRLNHPNIVRLYDWFED-KDHIY-MVMEYCEGGLY

--SLS----KSSWKADPL--PEAEAKNTFRQIASALQYLHSLDIIHRDLKPENILCFADGHS----AISDFSVSLKL-EDPNEMLEDTEGTPVFYSPEQC
  .|.       |.  ..  .| |.|. ..||...|.|.||  ||||||||||||.  .||      |.|| .. .. . .|. . .  ||| . .|| .
VMDLFDYIST--WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVI

SGEPYLGKPADCWAFGIVLYLMIFGKLPFFEADDEEIYRTHFFHISQVISTEELTYPDTS------------------NLSNELVDLFHHILDRNPATRY
 | .| |...| |..|..|| |..|..|| ......  ... . | .. ...     ...                  |.| |. |.   .|...|. |.
RGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRP

NMDQICSHKWF
. .||. |.||
TAEQILQHPWF
Kinase 83945.m00092.AA Ciliate-E2 92-363 22 1.3e-58 199.87 In-house 1-365 (365) Show / Hide 
Range on Protein: 92-363
Range on HMM: 1-365/365
Sequence Identity: 22% (87 aa)

YEFQQHIGHGSASDVFLVKNQETGIMYAAKVYDQDY------------LYRMSIGESVPPIEKVSREIQLMSEIN----------------HPNIVPLIE
|.|.. || |. ..|...|. ... ..| |. | ..             .      .   || ...||..| |||                ||||. ..|
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

ILDDQPTHSLIIILPFAEKGSLSK---SSWKAD--------PLPEAEAKNTFRQIAS---------------ALQYLHSLD-IIHRDLKPENILCFADGH
   .. .... ... ... |.| .   ...|          .. | |.|. ..||..               ||.||||   |||||.||||||      
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

SAISDFSVSLKLEDPNE---------MLEDTE-----------------------GTPVFYSPEQCSGEPYLG--------KPADCWAFGIVLYLMIFGK
  |.||  | |. |.|.         .. .                         ||| . .||  .|..| .        . .| |..|..|| |.|||
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

LPFFEADDEEIYRTHFFHISQVISTE-ELTYP----------------DTSNLSNELVDLFHH----ILDRNPATRYN-MDQICSHKWF
.||                 | .  . .. .|                .. ..|.|  ||.      .|...|  |.. ..||  |.||
PPF-----------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 83945.m00092.AA AGC 92-363 20 5.9e-58 147.39 In-house 1-395 (395) Show / Hide 
Range on Protein: 92-363
Range on HMM: 1-395/395
Sequence Identity: 20% (85 aa)

YEFQQHIGHGSASDVFLVKNQ------ETGIMYAAKVYDQDY--------LYRMSIGE-------SVPPIEKVSREIQLMSEIN----------HPNIVP
.||  .|| || . |.||.         || .|| || . ..          .. . |              | .| . ....|          ||.|| 
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGY------VWEERNILEKCNHTHNHPIKSHHPFIVK

-LIEILDDQPTHSLIIILPFAE--------KGS-LSKSSW----KADPLPEAEAKNTFRQ-------IASALQYLHS-LDIIHRD-LKPENILCFADGHS
 |     |.    | ... ...         |   . ..     |   ..| .|.  . .       |..||.|||| ..||||| |||||||  .||| 
ILHYSFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHI

AISDFSVSLKLED--------------------------------PNEMLEDT---------E---------G--TPVFYSPEQCSGEPYLGKPADCWA-
 ..||  . .. .                                ||.....          .         |  || . .||        ||..| |. 
KLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSF

-FGIVLYLMIFGKLPFFEADDE---EIYRTHFFHISQVIS------TEELTYPDT--------SNLSNELVDLFHHILDRNPATRYN----------MDQ
 .|...| |..|. ||.  ...      ... . . | |       ......|.         ...|.|..||  . | ..|. |             ..
GLGCLMYEMLTGYPPFYGDNPQENRH-PFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEE

ICSHKWF
| .|.||
IKNHPWF
Kinase 83945.m00092.AA Meta 92-363 32 2.4e-53 152.42 In-house 1-287 (287) Show / Hide 
Range on Protein: 92-363
Range on HMM: 1-287/287
Sequence Identity: 32% (98 aa)

YEFQQHIGHGSASDVFLVKNQETGIMYAAKVYDQDYLYR--MSIGE---------------SVPPIEKVSREIQLMSEINHPNIVPLIEILDDQPTHSLI
| ..  || ||   | |  | |.   || |. .   | .  . ..                   |...| .||  .   .|||.| |.|.|||  . .| 
YRLMEEIGKGSYGVVKLAYNEEDHHHYAMKILSKKKLLKQYGFMRRPPPRGNKPNQGGCIQPRNPLDRVYQEIAILKKLDHPNVVKLVEVLDDPNEDYLY

IILPFAEKGSLSKSSWKA---DPLPEAEAKNTFRQIASALQYLHSLDIIHRDLKPENILCFADGHSAISDFSVSLKLEDPNEMLED--TEGTPVFYSPEQ
..  . |||.       .    ||.|  |   || |   | |||   |||||.||.| |   |||  | || || . |.   .| .  | ||| |  || 
MVFEYVEKGPV----MEVPCDNPLSEDQAWSYFRDIVCGLEYLHYQKIIHRDIKPSNLLLNDDGHVKIADFGVSNEFEGDDAFLCNGSTAGTPAFMAPEA

CSGE--P-YLGKPADCWAFGIVLYLMIFGKLPFFEADD--EEIYRTHFFHISQVISTEELTYPDTSNLSNELVDLFHHILDRNPATRYNMDQICSHKWF
|| |  . | |. .| || |. || ..||. ||    |  . |   |     . | ......|.   .|..| |..   || || .|    .| .|.| 
CSEEQNHFYCGRALDVWAMGVTLYCFVFGQCPFI---DKTNYIMCLH-----DKIKNHPVMFPEQPEISEDLKDCIKRMLDKNPEHRIMIPEIKTHPWV
Kinase 83945.m00092.AA CAMKK-Unclassified 197-363 27 2.1e-50 162.25 In-house 177-392 (392) Show / Hide 
Range on Protein: 197-363
Range on HMM: 177-392/392
Sequence Identity: 27% (61 aa)

EAEAKNTFRQIASALQYLHSLD---------------------IIHRDLKPENILCFADGH-----SAISDFSVSLKLEDPNEM-LEDTEGTPVFYSPEQ
|  .|  |||.. .|||.|                        |||||.||.|||.  ..        |.||..|...|. ..  | ...||. | .||.
EQYLKKYFRQCCKGLQYMHNFNQACSYIIIYINEFDKIDHFQDIIHRDIKPQNILIDHEDNDKGEHFKIADFGISVIMEHEQQKKLKNNAGTYCFMAPEF

CSGE----PYLG-----------------------KPADCWAFGIVLYLMIFGKLPFFEADDEEIYRTHFFHISQVISTEELTYPD--TSNLSNELVDLF
.| |    .|..                       | || |. |. .| |....|||.. ...|.         |.|   |.  |    ...| |..||.
WSKENFKYDYNDYSFLPGTFNPLRKTYRIERICFYKKADIWSLGVTFYCMVYHSLPFWHKNLQELFH-------QMICQKEINFPPQYHPHCSHEFKDLI

HHILDRNPATRYNMDQICSHKWF
   .| || .| . ||.  | ||
QKMCDKNPKKRITIDQMLVHPWF
Kinase 83945.m00092.AA Ciliate-E2-Unclassified 92-363 23 3.2e-50 172.39 In-house 1-352 (352) Show / Hide 
Range on Protein: 92-363
Range on HMM: 1-352/352
Sequence Identity: 23% (82 aa)

YEFQQHIGHGSASDVFLVKNQETGIMY-----AAKVYDQDYLYRMSIGESVPPIEKVSREIQ-------------LMSEINHPNIVPLIEILDDQPTHSL
|.... ||.|. ..|..... ...  |     . |. ... .. |.       ..|   ...             ... ..||.|| ....  |. .  .
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQN--I

IIILPFAEKGSLSK---SSWK--------------ADPLPEAEAK-----NTFRQIASALQYLHSLD-IIHRDLKPENILCFADG---HSAISDFSVSLK
.|.. ..| |.|..   ...|                 ..| .||     . |.|| ..|.|||.   |||||.||||||   .|   .  |.||. | |
YIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKK

LEDP---------------NEMLEDTEGTPVFY----SPEQCSGEPYLG---KPADCWAFGIVLYLMIFGKLPFFEADDEE--IYRTHFFH------ISQ
....               ..|. .. ||| .     .||   |. | .   . .|.|..|..|| |.||..||.  ..|.  .. | . .      . |
YQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQ

VISTEELTYPDTSN------LSNELV----DLFHHILDRNPATRYNMDQICSHKWF
 |   .. .|  ..      .|.|      ||.. .|. ||  |....||. | ||
NIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 83945.m00092.AA ULK 92-363 24 3.3e-42 146.55 In-house 1-324 (324) Show / Hide 
Range on Protein: 92-363
Range on HMM: 1-324/324
Sequence Identity: 24% (81 aa)

YEFQQHIGHGSAS-DVFLVKNQET---GIMYAAKVYDQDYLYRMSIGESVPP----IEKVSREIQLMSEIN---HPN--IVPLIEILDDQPTH-SLIIIL
|.  . .|.||    |.  .|..|   .  .|.|. |...   |.. ..  .    ...  .|||.| ...   |||  || |.... .. .|  . ||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKK---MNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETS-NHNNIYIIM

PFAEKGSLSKSSWKADP---------LPEAEAKNTFRQIASALQYLHSLDIIHRDLKPENILCFADGHSA------------ISDFSVSLKLEDPN---E
 . . | |..   |  .         |.| ||.. |.||......||.  |||||.||.|||   . ..             |.||  . .....|    
EYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQ

MLEDTE------GTPVFYSPEQCS----GEPYLGKPADCWAFGIVLYLMIFGKLPFFEADDEEIY-RTHFFHISQ------VISTEELTYP---DTSNLS
|.  .       ||| . .|.  .    ..||  . .| | .|...| |..|| |||.   .. | . .  .| .       | .. . .|   .  ..|
MCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPPKDPKIS

NELVDLFHHILDRNPATRYNMDQICSHKWF
.|. ||.   | ...  | . ..| .|.||
PECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 83945.m00092.AA MARK 92-230 36 2.7e-30 96.36 In-house 1-136 (262) Show / Hide 
Range on Protein: 92-230
Range on HMM: 1-136/262
Sequence Identity: 36% (53 aa)

YEFQQHIGHGSASDVFLVKNQETGIMYAAKVYDQDYLYR-MSIGESVPPIEKVSREIQLMSEINHPNIVPLIEILDDQPTHS--LIIILPFAEKGSLSKS
|.. . ||||| . | |. .. ||. .| |.|.   | .  .       ...| |||..|. ..||||. | .. . |.| .  . .|.  |..|.|   
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQW-------MKNVMREIEIMKKLDHPNIIKLFHVIE-QDTEQHQIYLIMEYASGGELYDY

SWKA--DPLPEAEAKNTFRQIASALQYLHSLDIIHRDLKPENIL
  ..   .|.| ||.  |||| ||..|.|| .|.|||.||||||
IKAHPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENIL
Kinase 83945.m00092.AA MARK 260-363 30 2.4e-23 73.32 In-house 167-262 (262) Show / Hide 
Range on Protein: 260-363
Range on HMM: 167-262/262
Sequence Identity: 30% (32 aa)

GTPVFYSPEQCSGEPYLGKPADCWAFGIVLYLMIFGKLPFFEAD--DEEIYRTHFFHISQVISTEELTYPDTSNLSNELVDLFHHILDRNPATRYNMDQI
||| . .||  ...|| |...| |. |.||| |. |..|| ...  ..|.|.         | ... ..|.   .| |. .| . .|  ||  |  ...|
GTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYK--------KILRGKYDIPCH--VSKECRNLIQRLLTVNPEERPTIEEI

CSHKWF
 .|.|.
MKHPWM
Kinase 83945.m00092.AA TyrKc 92-363 19 7.4e-12 -30.98 SMART 1-280 (280) Show / Hide 
Range on Protein: 92-363
Range on HMM: 1-280/280
Sequence Identity: 19% (60 aa)

YEFQQHIGHGSASDVFLVKNQETGIMYAAKVYDQDYLYRMSIGESVPPIEKVSREIQLMSEI--NHPNIVPLIEILDDQ-----PTHSLIIILPFAEKGS
 .. . .|.|    |.. .     |. | |.   |             .|   ||...|...  .||||| |. .  .|       . | |.. ....|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGD

LS---KSSWKADPLPEAEAKNTFRQIASALQYLHSLDIIHRDLKPENILCFADGHSAISDFSVSLKLEDP-------NEMLE----DTEG-TPVF-YSPE
|    ... .   |. ..  .   |||.  .||||  .|||||   |.|  ....  ||||  | ...|                 .. .  |.  ..||
LKDYLRKHRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPE

QCSGEPYLGKPADC--------WAFGIVLY-LMIFGKLPFFE-----ADDEEIYRTHFFHISQVISTEELTYPDT------SNLSNELVDLFHHILDRNP
            ..        |.||.... .. .|. |  .      ...|...       .| . . .  |.          . |. ..     ...|
CI---------NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIE-------YVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDP

ATRYNMDQICSHKWF
. | .. .|  |. |
EDRPTFSEI--HECF
Kinase 83945.m00092.AA CAMKK-Unclassified 92-193 25 8.5e-08 21.15 In-house 1-118 (392) Show / Hide 
Range on Protein: 92-193
Range on HMM: 1-118/392
Sequence Identity: 25% (30 aa)

YEFQQHIGHGSASDVFLVKNQET-----GIMYAAKVYDQDYLYRMSIGESVP---PIEK-----VSREIQLMSEINHPNIVPLIEILDDQPTHSLII--I
||| . .|.||   | |...  |      . .| ||.  . |... .   .     ..|     |  ||  |  ..||||. | |. ||.    .    .
YEFLDKLGRGSFGKVKLATRRYTTDDGVQKQFAIKVFKKQKLKKKKFIYNDNAFTMKMKNRLHLVQQEIAIMKKLWHPNICKLYEVIDDPDNDKIYMGQV

LPFAEKGSLSKSS-WKAD
. ....|.. ... ||.|
MEYCQMGQIMSWDYWKQD
Kinase 83945.m00092.AA Pkinase_Tyr 205-224 55 0.000484 14.31 Pfam 118-137 (270) Show / Hide 
Range on Protein: 205-224
Range on HMM: 118-137/270
Sequence Identity: 55% (11 aa)

RQIASALQYLHSLDIIHRDL
.|||....||.|  .|||||
WQIAKGMEYLESKNCIHRDL
Kinase 83945.m00092.AA Pkinase_Tyr 145-185 29 0.001539 12.61 Pfam 52-94 (270) Show / Hide 
Range on Protein: 145-185
Range on HMM: 52-94/270
Sequence Identity: 29% (13 aa)

REIQLMSEI-NHPNIVPLI-EIL-DDQPTHSLIIILPFAEKGSL
||...|... .||||| |.  .. ...|  ...|.......|.|
REAKIMKQLGHHPNIVRLYGVCTDQGEPN-QIYIVMEYMPHGDL