120966.m00016

Species: T.vaginalis
Alias: 120966.m00016, TvagK0001
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
120966.m00016.AA Protein None 353 None Fasta, JSON
120966.m00016.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of 120966.m00016.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 120966.m00016.AA CAMKL 23-275 35 1.4e-103 331.43 In-house 1-297 (297) Show / Hide
Range on Protein: 23-275
Range on HMM: 1-297/297
Sequence Identity: 35% (105 aa)

YEFVRKIGYGSFSSVVLVRH-LKTKEYFACKIVSRKMLE-EQQIFSR-----------FEQEVRLMQSFN---HPYVIHTFDVVFDPQY------IYIVM
|.... .| |||. | | .| . |.|  | ||. .| .  .... ..            ..|...|...|   || .|. ..|. .|..      ||.||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCPNGE--LFSYILSL----VRLPEMEVNRILRQILQALQYIHSKKVAHRDIKPENILLDSHMD--IRLSDFGLCKEMS-H----GSLLKTPCGSPFYA
|||..||  || || .      |.|| |  |. |||. |..|.||....||||||||||||....  | ..|||.. ..  .    | .||| |||| |.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

PPEIINN--DKYDGVKSDIWSLGVVVFTMSTGALPWSHT--------NHAQLFKQITTTDVTVP--QGLSPPLRQIITLMLQRDPNARPTPTELLAMPWL
.|||..   ..||| | ||||.||. ..| .|.||.           |.  |...| ..    |    .| ..|..|  |||..|. |||  ...  ||.
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM





Kinase 120966.m00016.AA CAMK 28-275 22 3.8e-103 333.25 In-house 1-425 (425) Show / Hide
Range on Protein: 28-275
Range on HMM: 1-425/425
Sequence Identity: 22% (97 aa)

KIGYGSFSSVVLVRHLKTK------------EYFACKIVSRKMLEE-------------------------QQIFSRFEQEVRLMQS-------FNHPYV
..| |||. | |..| .|.            . .|.||...| | .                         ..   ....|...|..        .|| .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IHTFDVVFD-------------------PQYIYIVM---EYCPNGEL----FSYILSL---------------VRLPEMEVNRILRQILQALQYIHSKKV
|. ..|  |                   ....|.||   |||..|||    |.|| .                 |..| |. |. |||..|..|.||...
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

AHRDIKPENILLDSHM-----------------DIRLSDFGLCKEMSH------------------------GSLLKTPCGSPFYAP-PEIINN------
.|||.||||||||...                 .| ..|||. ... .                        | ..||.||.| |.. ||..|       
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------DKYDGVKSDIWSLGVVVFTMSTGALPWSHT-------------NHAQLFKQITTTDVT-VPQGLSP-----------------------PLRQ
        .|.| |.|.||.||. ..| .| .|. .              |  .||..|.. . .  |  .||                         ..
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

IITLMLQRDPNARPTPTELLAMPWL
 |  |||.||. |.| .. |. ||.
LIRKMLQVDPEKRMTIEQCLNHPWM

S_TKc 120966.m00016.AA S_TKc 23-275 34 2.8e-101 343.69 SMART 1-231 (231) Show / Hide
Range on Protein: 23-275
Range on HMM: 1-231/231
Sequence Identity: 34% (92 aa)

YEFVRKIGYGSFSSVVLVRHLKTKEYFACKIVSRKMLEEQQIFSRFEQEVRLMQSFNHPYVIHTFDVVFDPQYIYIVMEYCPN--GELFSYILSLVR---
||..|||| |.|..| ..|| ||....|.||..           ....|...... .||.... .||  | ...|.|||||..  |.||.|| .  |   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LPEMEVNRILRQILQALQYIHSKKVAHRDIKPENILLDSHMDIRLSDFGLCKEMSHGSLLKTPCGSPFYAPPEIINNDKYDGVKSDIWSLGVVVFTM
   .|| .. ....||..||.|.||... |||.||||||||.   | ..||||....      .| ||.|.| .||..   .|.. |.|.||.|.... |
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

STGALPWSHTNHAQLFKQITTTDVTVPQGLSPPLRQIITLMLQRDPNARPTPTELLA-------MPWL
 .|  |..  .....||.|           ||.....|  .||.||. |||  |.|.       .||.
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 120966.m00016.AA AMPK 23-275 39 3.7e-98 292.0 In-house 1-254 (254) Show / Hide
Range on Protein: 23-275
Range on HMM: 1-254/254
Sequence Identity: 39% (100 aa)

YEFVRKIGYGSFSSVVLVRHLKTKEYFACKIVSRKMLEEQQIFSRFEQEVRLMQSFNHPYVIHTFDVV-FDPQYIYIVMEYCPNGELFSYILSLVRLPEM
|    .|| |.|  | .  |  |.|. | ||  .... .|.   | . |......|.|| .|  ..|.   |. |..|||| ..||||.|| .  ||.| 
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EVNRILRQILQALQYIHSKKVAHRDIKPENILLDSHMDIRLSDFGLCKEMSHGSLLKTPCGSPFYAPPEIINNDKYDGVKSDIWSLGVVVFTMSTGALPW
|  | . ||. .. |.|  ...||| ||||.||| .. | . |||| . |. | .||| |||| || ||.| . .| | . |||| ||. . |  | || 
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

SHTNHAQLFKQITTTDVTVPQGLSPPLRQIITLMLQRDPNARPTPTELLAMPWL
   | ..|.| |.  ....|. |||  ...|  ||| ||. | |  .. . ||.
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF

Kinase 120966.m00016.AA MARK 23-275 38 9.5e-98 320.07 In-house 1-262 (262) Show / Hide
Range on Protein: 23-275
Range on HMM: 1-262/262
Sequence Identity: 38% (101 aa)

YEFVRKIGYGSFSSVVLVRHLKTKEYFACKIVSRKMLEEQQIFSRFEQEVRLMQSFNHPYVIHTFDVVF--DPQY-IYIVMEYCPNGELFSYILSL--VR
|.... || ||.. | |..|..|.. .| ||. .. | . | .. .. |...|.. .||..|  |.|.   ..|  ||..|||...|||..|| .    |
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LPEMEVNRILRQILQALQYIHSKKVAHRDIKPENILLDSHM--DIRLSDFGLCKEMSHGSLLKTPCGSPFYAPPEIINNDKYDGVKSDIWSLGVVVFTMS
|.| |  || |||. |..| ||| ..||||||||||.|...  .| ..|||.. .   |..|.| ||.| |..|||..  .||| | |||||||| ..| 
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

TGALPWSHTN--HAQLFKQITTTDVTVPQGLSPPLRQIITLMLQRDPNARPTPTELLAMPWL
.| .|.  ..    .|.|.|.. . ..|  .|. .|..| ..|. .|. ||| .|..  ||.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase 120966.m00016.AA Pkinase 23-275 30 1e-95 329.1 Pfam 1-293 (293) Show / Hide
Range on Protein: 23-275
Range on HMM: 1-293/293
Sequence Identity: 30% (91 aa)

YEFVRKIGYGSFSSVVLVRHLKTKEYFACKIV---SRKMLEEQQIFSRFEQEVRLMQSFNHPYVIHTFDVVFDPQYIYIVMEYCPNG----ELFSYIL--
|...|||| |||..| . .| .| . .|.||.   ..|. ..|. . .  .|...|...|||... ..|.. |...||.|||||..|    .||.||   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL--SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

SLVRL--PEMEVNRILRQILQALQYIHSKKVAHRDIKPENILLDSHMDI----RLSDFGLCKE--MSHGSLLKTPCGSPFYAPPEIINNDKYDGVKSDIW
.  ..  .| |. ....|||..|.|.||... |||.||||||.|....|    ...||||.|     ..| ..|.||.|.|..||.|. ..|.| |.|.|
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SLGVVVFTMSTGALPWSHT------NHAQLFKQITTTDVTVPQGLS---------------------PPLRQIITLMLQRDPNARPTPTELLAMPWL
|.|.... | .| .|...       .. |....|  ...  .   .                     ......|. .|..||. |||....|  ||.
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 120966.m00016.AA Ciliate-E2 23-275 26 5.4e-79 268.74 In-house 1-365 (365) Show / Hide
Range on Protein: 23-275
Range on HMM: 1-365/365
Sequence Identity: 26% (99 aa)

YEFVRKIGYGSFSSVVLVRHLKTKE-----------------------YFACKIVSRKMLEEQQIFSRFEQEVR----------LMQSFNHPYVIHTFDV
|.|..||| |.|.|| .... |...                       ..| ||.. ...|..    .  .|..          .... |||..|  ...
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VF--DPQYIYIVMEYCPNGELFSYILSL-----------VRLPEMEVNRILRQILQ---------------ALQYIHSKK-VAHRDIKPENILLDSHMDI
    | ..||.|||||  |.||.|| .             .. | |. .| .||||               ||.|.|||. . ||||||||||.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

RLSDFGLCK----------------EMSHGS-----------------LLKTPCGSPFYAPPEIINNDKYDG--------VKSDIWSLGVVVFTMSTGAL
 ..||||.|                ..   .                 . .| ||.| | .|||.|. |||.         |.|||||||. . | .| .
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PWSHTNHAQLFKQITTTDVTVP------------------QGLSPPLRQIITL----MLQRDPNARPT-PTELLAMPWL
|.        ..||   ..  |                  . .|.   ..|      |||.||. |.| . ..|  ||.
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 120966.m00016.AA Ciliate-E2-Unclassified 23-275 26 4.6e-78 265.64 In-house 1-352 (352) Show / Hide
Range on Protein: 23-275
Range on HMM: 1-352/352
Sequence Identity: 26% (94 aa)

YEFVRKIGYGSFSSVVLVRHLKTKEYF-----ACKIVSRK----------MLEEQQIFSRFEQEVR--------LMQSFNHPYVIHTFDVVFDPQYIYIV
|.....|| |.|..| ...| |.| ..     ..|| ..|          |.|....... .  .|        ......||.... |..  | |.||||
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEYCPNGELFSYILSL-----------------VRLPEMEVN-----RILRQILQALQYIHSKK-VAHRDIKPENILLDSHM---DIRLSDFGLCK----
||||..|.|. || .                   ...| ..      ....||||.|.|.|.|. . ||||||||||.|. .    |...|||..|    
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

------------EMSHGSLLKTPCGSPFYA----PPEIINNDKYDG---VKSDIWSLGVVVFTMSTGALPWSHTNHAQ----------------LFKQIT
             .    ...| ||.| |     .||.. . .||.    |.|||||||. . | .| .| . .|  |                |...| 
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

TTDVTVP--------QGLSPPLRQIIT----LMLQRDPNARPTPTELLAMPWL
  .. .|        ...||    .|.     ||. .|| |.|. ..|  ||.
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 120966.m00016.AA ULK 23-275 26 2.2e-74 253.42 In-house 1-329 (329) Show / Hide
Range on Protein: 23-275
Range on HMM: 1-329/329
Sequence Identity: 26% (86 aa)

YEFVRKIGYGSFSSVVLVRHLKTK----EYFACKIVS----RKMLEE---QQIFSRFEQEVRLMQSFN--------HPYVIHTFDVVFDP--QYIYIVME
|.  ...| |||  |   |. |||    |..|||...    .. . |   |..   ...|...|.  .        ||...  .|.  ..   .|||.||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCPNGELFSYILSL----------VRLPEMEVNRILRQILQALQYIHSKKVAHRDIKPENILLDSH------------MDIRLSDFGLCKEMSHG----S
||. | |..||              ||.|.|.  ...|||......|.... ||||||.|||.. .            . . ..|||..| .. .     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

LLKTPC------GSPFYAPPEIINND----KYDGVKSDIWSLGVVVFTMSTGALP---WSHTNHA-----QLFKQ-------ITTTDVTVP-----QGLS
...|        |.| |  |.|...     .|.  |.||||||.. . | .|  |   |  .        .|...       | ..    |     . .|
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

PPLRQIITLMLQRDPNARPTPTELLAMPWL
| ....|  |||.|.. | . .||...||.
PECKDLIRRMLQYDEKDRISWEELFNHPWF

Kinase 120966.m00016.AA ULK 23-275 25 9.6e-74 251.31 In-house 1-324 (324) Show / Hide
Range on Protein: 23-275
Range on HMM: 1-324/324
Sequence Identity: 25% (83 aa)

YEFVRKIGYGSFS-SVVLVRHLKT---KEYFACKIVS----RKMLEE---QQIFSRFEQEVRLMQSFN---HPY--VIHTFDVVFDP--QYIYIVMEYCP
|.  ...| |||   |   |. ||   ..|.|||...    .|   |   |..   ...|...|. ..   ||.  ..  .|.  ..   .|||.||||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGELFSYILSLVR---------LPEMEVNRILRQILQALQYIHSKKVAHRDIKPENILLDS------------HMDIRLSDFGLCKEMSHG----SLLKT
 | |..||    .         |.|.|.  ...||.......|.... ||||||.|||.              .  . ..|||..|    .     ...|
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

PC------GSPFYAPPEIINND----KYDGVKSDIWSLGVVVFTMSTGALP---WSHTNHA----QLFKQ-------ITTTDVTVP-----QGLSPPLRQ
 .      |.| |  |.|...     .|.  |.||||||.. . | .|  |   |  ..      .| ..       | .. .  |     . .|| ...
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

IITLMLQRDPNARPTPTELLAMPWL
.|  |||.|.. | . .|....||.
LIRRMLQYDEKDRISWEEIFNHPWF

Kinase 120966.m00016.AA RSK 26-275 28 2.9e-72 246.39 In-house 3-278 (278) Show / Hide
Range on Protein: 26-275
Range on HMM: 3-278/278
Sequence Identity: 28% (78 aa)

VR-KIGYGSFSSVVLVRHLKTKEYFACKIVSRKMLEEQQI-FSRFEQEVRLMQSFN-HPYVIHTFDVVFDPQYIYIVMEYCPNGELFSYILSLVR---LP
|  ..|||... .  ..| .|. ..| |.......   |    .  .|.. ..  . || ... ...  .....|..||||. ||||  ..  ..   . 
VLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCFS

EMEVNRILRQILQALQYIHSKKVAHRDIKPENILLDS---HMDIRLSDFGLCKEM--SHGSLLKTPCGSPFYAPPEIIN---NDK-YDGVKSDIWSLGVV
| |.  ....|  |....|.... |||.||||||.|.   .  |.|.|||.||..  .|.....|.|..  |..||...    .. .|    |.|||||.
EDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHD-KACDWWSLGVL

VFTMSTGALPWSH---TNHAQLFKQITTTD--VTVP--QGLSPPLRQIITLMLQRDPNARPT-----PTELLAMPWL
 ..| ||..|  .    |.....|.| . .  .| |  | ||.. . .|. ||.|||. |..       |... ||.
MYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase 120966.m00016.AA STE 23-275 24 1.3e-71 244.26 In-house 1-359 (359) Show / Hide
Range on Protein: 23-275
Range on HMM: 1-359/359
Sequence Identity: 24% (90 aa)

YEFVRKIGYGSFSSVVLVRHLK---------------TKEYFACKIVS----RKMLEE-----------QQIFSRFEQEVRLMQSFN--HPYVIHTFDVV
.|...||| |.| .|.. .. |               |.|..| |...    ...  |           .... ....|...|. .|  ||.... ..  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

FDP-------QYIYIVMEYCPNGELFSYILSL--------------VRLPEMEVNRILRQILQA-LQYIHSKKVAHRDIKPENILLDSHMDIRLSDFGLC
|.        ....|.|||...| | . | .                |.|| .. .|.||||.. |.|.||... |||||| ||||     . |.|||.|
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVC

KEMSH-----------------GSLLKTPCGSPFYAPPEIINN-----DKYDGVKSDIWSLGVVVFTMSTGALPWSH-TNHAQLFKQITT----------
. ...                 ..  .| .|.| .  ||.|..     ||  ..|.|||||| ..  | ||  ||.  ...  .|  ..           
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

-----TDVTVPQGLS-------------------PPLRQIITLMLQRDPNARPTPTELLA--MPWL
     .  . |. ||                   |.... | . ||.||| |||...||    |..
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI

Kinase 120966.m00016.AA TyrKc 23-275 22 5.3e-18 67.06 SMART 1-280 (280) Show / Hide
Range on Protein: 23-275
Range on HMM: 1-280/280
Sequence Identity: 22% (66 aa)

YEFVRKIGYGSFSSVVLVRHLKTKEYFACKIVSRKMLEEQQIFSRFEQEVRLMQSF--NHPYVIHTFDVVFDP-------QYIYIVMEYCPNGELFSYIL
 .. .|.| | |  |.. .            |  ||| |      | .| |.| ..  .|| ..  . |. ..       . ..|||||.|.| | .|. 
ITLGKKLGEGAFGEVYKGTWK--------IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

SLVR-LPEMEVNRILRQILQALQYIHSKKVAHRDIKPENILLDSHMDIRLSDFGLCKEMSHG-------SLLKT----PCG--SP-FYAPPEIINNDKYD
.  . |.  .   .  || .  .|.|||.. |||.   |.|...   .. |||||...  ..       .  ..     .    |    .|| ||  |. 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

GVKSDIWSLGVVVF-TMSTGALPWSH-----TNHAQLFKQITTTDVTVPQGL---------SPPLRQIITLMLQRDPNARPTPTELLAMPWL
  |||.|| ||. .  .. |. |..       . ....... . .   .            .. . ||..   ..||. ||| .|.     .
-TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase 120966.m00016.AA Pkinase_Tyr 23-212 27 1.2e-17 60.43 Pfam 1-205 (270) Show / Hide
Range on Protein: 23-212
Range on HMM: 1-205/270
Sequence Identity: 27% (58 aa)

YEFVRKIGYGSFSSVVLVRHL----KTKEYFACKIVSRKMLEEQQ-IFSRFEQEVRLMQSF-NHPYVIHTFDVVF---DPQYIYIVMEYCPNGELFSYIL
 .| .|.| |.| .|.. .      .||   | |.. .    ..| .   | .|...| .. .|| ..    |.    .|..|||||||.|.| | .|  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

S----LVRLPEMEVNRILRQILQALQYIHSKKVAHRDIKPENILLDSHMDIRLSDFGLCKEM-------SHGSLLKTPCGSPFYAPPEIINNDKYDGVKS
.      .|.  .   . .|| ....| .||.  |||.   |.|... . .. .||||.. .         ..  | |    .  .|| ||. |.  .||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLP---IKWMAPECINYGKFT-TKS

DIWSLGVVVF
|.|| ||. .
DVWSFGVLMW