Gene 88546.m00247 (T.vaginalis)

88546.m00247

Species: T.vaginalis
Alias: 88546.m00247, TvagK0303
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
88546.m00247.AA Protein None 881 None Fasta, JSON
88546.m00247.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of 88546.m00247.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 88546.m00247.AA TKL 40-287 22 3.5e-61 209.57 In-house 1-364 (364) Show / Hide 
Range on Protein: 40-287
Range on HMM: 1-364/364
Sequence Identity: 22% (85 aa)

IGKGGFGEVNLARYTK--------DGNLYAVKQIFEKR--LHGN-----------------------AFRRFLDEVKTMAKCLDDFLLPISGFTFTAP--
||.||||||  ...          .|.  |||.. ..   ..                         .. ..  |.. | ..  . .... |. .  |  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YSIITPYIPSGCLKDYVSKKSAVKLTPTQLTKIAMGIAHGMIVVHENN--------IIHRDLKTANILMDEHLL--------------
            . |.. |.| |.| .|.         . |. ..|..|| ||   | .|        |||||||..||| ||..               
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

PKICDFGIARFEGIGESNLMTA------------------GIGTSIYMAPELYA----------------TRTYSNKVDVYSYAFILWEMSEKKRAFATI
.||||||..||    ... .|.                   .||  .||||.                   ..|| |.||||.. .|||.   .| .. .
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY

KPEKLH---------EKIYQKGERETFS------------MQTPRALQTLIKKCWDADPSKRPSFQNIYNAF
...            .....||.| .               ..|. .  |...|||.||.|||||| |   .
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 88546.m00247.AA TKL-Unique 36-287 29 2.3e-58 200.21 In-house 1-290 (290) Show / Hide 
Range on Protein: 36-287
Range on HMM: 1-290/290
Sequence Identity: 29% (87 aa)

IQNTIGKGGFGEVNLARYTKDGNLYAVKQIFEKRLHGNAFRR-FLDEVKTMAKCLD--DFLLPISGFTF----TAP-YSIITPYIPSGCLKDYVSK----
. |.|| ||.|.|  . . ..   .|.||.... .  | ... | .||..| |.|.  .... . |...    ..| ..|.. |.| | | |. .     
FWNKIGEGGYGQVYKGKWRGY--PVAIKQFHPNEDSSNEMMQEFENEVNWM-KKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNN

----KSAVKLTPTQLTKIAMGIAHGMIVVHENN--IIHRDLKTANILMDEH-----LLPKICDFGIARFEGIGESNLMTAG----------IGTSIYMAP
    ..  ||.. |  |.|  || ||.  | ..  |||||||. |.| |..     .  ||||||...|     .| ||..          .|. ..|||
NNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKF--NSKINKMTNNEHKGTRNQTRCGSFRWMAP

ELYAT--RTYSNKVDVYSYAFILWEMSEKKR------AFATIKPEKLHEKIYQ--KGERETFSMQTPRALQTLIKKCWDADPSKRPSFQNIYNAF
|.      .||.|.||||....|||. . |.       .  . .|.. |.. .  .. |.. ..  |  .. ||..||. |||.||||..|..  
EVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
S_TKc 88546.m00247.AA S_TKc 34-288 27 1.8e-47 164.97 SMART 1-231 (231) Show / Hide 
Range on Protein: 34-288
Range on HMM: 1-231/231
Sequence Identity: 27% (75 aa)

YEIQNTIGKGGFGEVNLARYTKDGNLYAVKQIFEKRLHGNAFRRFLDEVKTMAKCLDDFLLPISGFTFTAPYSIITPYIPS--GCLKDYVSKKSAVK---
||| ..||||.||.| ..| .|.| ..|.|.|          .... |.. . |   ...  . ..  .  . ... |..   | |.||  |.   .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LTPTQLTKIAMGIAHGMIVVHENNIIHRDLKTANILMDEHLLPKICDFGIARFEGIGESNLMTAGIGTSIYMAPELYATRTYSN-KVDVYSYAFILWEM
 ... .  ...  |. ..   |...||||||| .|||.||    ||||||.||.         |  .||  |||||.     |.  |.|..|   ||.||
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

SEKKRAFATIKPEKLHEKIYQKGERETFSMQTPRALQTLIKKCWDADPSKRPSFQNIYN--------AFA
   .  |    .... .||            .| |.. .|.||.. ||.|||.   . .         . 
LCGYPPFP--QMQMMFKKIG-----------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 88546.m00247.AA Dicty4 136-289 31 6.5e-46 151.21 In-house 116-277 (277) Show / Hide 
Range on Protein: 136-289
Range on HMM: 116-277/277
Sequence Identity: 31% (51 aa)

KIAMGIAHGMIVVHE-N-NIIHRDLKTANILMDEHLLPKICDFGIAR-FEGIGESNL-MTAGIGTSIYMAPELYATRTYSNKVDVYSYAFILWEMSEKKR
..|  .| ||.  |. | .|||||||..|.|.|...  |.||||... .  . . .  ... .||  .||||  . . |  |.||||.. .|||.  .. 
RMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADVYSFGIVLWEILTRQE

AFA--TIKPEKLHEKIYQKGERETFSMQTPRALQTLIKKCWDADPSKRPSFQNIYNA--FAT
 ..   . .... . . .|..|   . ..|  . .||..||| ||..||||. | ..    .
PYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Pkinase 88546.m00247.AA Pkinase 34-287 24 2.6e-45 161.28 Pfam 1-293 (293) Show / Hide 
Range on Protein: 34-287
Range on HMM: 1-293/293
Sequence Identity: 24% (74 aa)

YEIQNTIGKGGFGEVNLARYTKDGNLYAVKQIFEKRLHGNAFRRFLD--EVKTMAKCLDDFLLPISGFT--FTAPYSIITPYIPSG----CLKDYVSKKS
|.|  .||.|.||.| ...  ..| ..|||.|  .. . .  .. .   |.. |...  .. . . ..    . .| ....| . |     |.||.| ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIY-MVMEYCEGGLYVMDLFDYISTWR

AVKL--TPTQLTKIAMGIAHGMIVVHENNIIHRDLKTANILMDEHLLP----KICDFGIAR-FEGIGESNLMTAGIGTSIYMAPELYA-TRTYSNKVDVY
  ..  .. .. ...  |. |.   |...||||||| .|||.|..  .    ||||||.|. |. .  .  ||   ||. |||||.    . |. |||..
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SYAFILWEMSEKKRAFATI----KPEKLHEKIYQKGERETFSMQT----------------------PRALQTLIKKCWDADPSKRPSFQNIYNA--F
|.  ||.||  ..  |       .     ..|........ .                         ..... .||.|.. ||.|||... | .   |
SCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 88546.m00247.AA Dicty5 107-293 36 1.8e-42 143.97 In-house 76-260 (260) Show / Hide 
Range on Protein: 107-293
Range on HMM: 76-260/260
Sequence Identity: 36% (69 aa)

IITPYIPSGCLKDYVSKKSA----VKLTPTQLTKIAMGIAHGMIVVHENNIIHRDLKTANILMDEHLLPKICDFGIARFEGIGESNLMTAGIGTSIYMAP
..| |. .| | .|   .        . ..||  .|..|| .|  .|  ||||||||  |.|  | .  || |||. ||  .     ||  .||. .||.
HVTEYCHNGSLFNYLNDQRKTTGQPIAYFQQL-HMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRF--VDNRYHMTMHVGTQCWMAC

ELYATRTYSNKVDVYSYAFILWEMSEKKRAFATIKPEKLHEKIYQKGERETFSMQTPRALQTLIKKCWDADPSKRPSFQNIYNAFATGKVS
||.  ..| .|.||||.. .||||  .| ..  |        . .|||| |     |     ||||||   |..||||  |   |   ...
ELFNGQPYHQKCDVYSFGIVLWEMFTRKEPYDNINNWNIP-VMVMKGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFE--SII
Kinase 88546.m00247.AA MLK 34-287 26 5.2e-41 140.01 In-house 1-291 (291) Show / Hide 
Range on Protein: 34-287
Range on HMM: 1-291/291
Sequence Identity: 26% (77 aa)

YEIQNTIGKGGFGEVNLARYTKDGNL-----YAVKQIF-------EKRLHGNAFRRFLDEVKTMAKCL-DDFLLPISGFTFTAPYS--IITPYIPSGCLK
 ...  ||.|.||.| ..|.   ...      |||...       ..     .|...  ... . .        .. |     |.   |.. |.. |.| 
IQFHEWIGSGSFGKVWKGRWR--NKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLY

DYV---SKKSA---------VKLTPTQLTKIAMGIAHGMIVVHENN---IIHRDLKTANILMDE------HLLPKICDFGIAR-FEGIGESNLMTAGIGT
..    ..|..         .  .. .. ..|. .|.||   |..    |||||||  ||| ||      |.  ||||||..| .  .. .| |.  .||
NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TN-MMSNAGT

SIYMAPELY---ATRTYSNKVDVYSYAFILWEMSEKKRAFA-TIKPEKLHEKIYQKGERETFSMQTPRALQTLIKKCWDADPSKRPSFQNIYNAF
 ..||||        .|| |.||.|.. .||||  ..  ..  ..|     .. ..|.| .   . |. .  |.|.||..||.|||||. |   .
YAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 88546.m00247.AA LRRK 104-289 30 8.6e-40 138.44 In-house 129-351 (351) Show / Hide 
Range on Protein: 104-289
Range on HMM: 129-351/351
Sequence Identity: 30% (68 aa)

PYSIITPYIPSGCLKDYVSKKSAVK-------LTPTQLTKIAMGIAHGMIVVHENN--IIHRDLKTANILM---D---------EHLLPKICDFGIAR-F
|. ... |.| | | .. ..|.  .       .... . |||. || ||   | .|  |||||||. |||.   .         .|   ||.|||| | |
PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMF

EGIGESNLMTAGIGTSIYMAPELYA---TRTYSNKVDVYSYAFILWE-MSEKKRAFATIK-PEKL--HEKIYQ---KGERETFSMQ-TPR-----ALQTL
  .  . .     |. ..||||      . .|. |||.||.. |||| .. . ..|  .. . ..  .|.| .   .| | |..    |.      .|.|
-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDL

IKKCWDADPSKRPSFQNIYNAFAT
|..||..|| |||.|. |     .
IQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 88546.m00247.AA RIPK 40-287 28 6e-39 130.36 In-house 1-290 (290) Show / Hide 
Range on Protein: 40-287
Range on HMM: 1-290/290
Sequence Identity: 28% (82 aa)

IGKGGFGEVNLARYTKDGNLYAVKQI--FEKRLH--GNAFRRFLDEVKTMAKCLDDFLLPISGFTFTA------P-YSIITPYIPSGCLKDYVSKKS--A
.|.|||||| .||  . |  .|.|     ..  |         . |.| |.|   .. .|| ||.           |.| . | ..| | .  . |.   
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

VKLTPTQLTK-IAMGIAHGMIVVHENN--IIHRDLKTANILMDEHLLPKICDFGIARFEGIGESNL----------MTAGI--GTSIYMAPELYATRTYS
 . .|  |.  .   |. ||   | .|  |||||||..||| | ..  || ||| | . .  .|.           |.     || .||.||.. |   .
HHPDPWPLRCRMIHEISCGMCYLHSMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNKK

N------KVDVYSYAFILWEMSEKKRAFATIKPEKLHEKIYQKGER---ETFSMQTPRA-----LQTLIKKCWDADPSKRPSFQNIYNAF
       | ||||.|...||   .| ...  |..   .   ..| |   .  . ..|..     .  |...||..|| .||.|| .   .
PIKVVTPKYDVYSFAIVMWEVLTQKHPYEDRKCMMMIMMCCKQGHRPCLQPVPEYWPEPPHCEQMIELMQRCWQQDPNDRPCFQECEEWT
Kinase 88546.m00247.AA Dicty4-Unclassified 107-287 33 4.2e-38 128.06 In-house 79-263 (263) Show / Hide 
Range on Protein: 107-287
Range on HMM: 79-263/263
Sequence Identity: 33% (63 aa)

IITPYIPSGCLKDYVS-----KKSAVKLTPTQLTKIAMGIAHGMIVVHENNIIHRDLKTANILMDEHLLPKICDFGIARFEGIGESNLMTAGIGTSIYMA
|..  ...| |   .      ..  .||  |   |.|. || ||   |  |.||||.| .||||| |   || ||||.|   |     ||.  ||    .
IVMEFMHKGNLFEVIHSKPSEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRV--IDFNFNMTTIAGTPKWES

PELYATRTYSNKVDVYSYAFILWEMSEKKRAFATIK-PEKLHEKIYQKGERETFSMQTPRALQTLIKKCWDADPSKRPSFQNIYNAF
||      |  | |||||| .|.|.      .  |  .  .   .  |. |   .   .  .. ||| ||  || |||..  | .  
PECLMHESYNQKSDVYSYAMMLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase 88546.m00247.AA HH498 137-287 34 6.1e-35 107.92 In-house 126-284 (284) Show / Hide 
Range on Protein: 137-287
Range on HMM: 126-284/284
Sequence Identity: 34% (55 aa)

IAMGIAHGMIVVHE---NNIIHRDLKTANILMDEHLLPKICDFGIARF-EGIGESNLMTAGIGTSIYMAPELYA-TRTYSNKVDVYSYAFILWEMSEKKR
|.. .||||   |.     ||||||   |||..|    .. |||. || . ... | ||  .|   .|||| .     || ||||.||| ..|||   . 
ISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMHDDN-MTKQPGNLRWMAPEVFSQCQKYSIKVDVFSYAMCIWEMHTREV

AFATIKPEKLHEKIYQKGERETFSMQ----TPRALQTLIKKCWDADPSKRPSFQNIYNAF
 |.  ||     ..  .  | .   .     |.    ||  ||.. |. ||.|  |    
PFHHYKPAAAAAEMAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL
Kinase 88546.m00247.AA TyrKc 34-287 24 3.4e-34 120.85 SMART 1-280 (280) Show / Hide 
Range on Protein: 34-287
Range on HMM: 1-280/280
Sequence Identity: 24% (72 aa)

YEIQNTIGKGGFGEVNLARYTKDGNLYAVKQIFEKRLHGNAFRRFLDEVKTMAKC--LDDFLLPISGFTFT--------APYSIITPYIPSGCLKDYVSK
 .   ..| | |||| .....      ||| . |        . |..| . | |     . .. . |   .         |. |.. | | |.||||  |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KSAVKLTPTQLTKIAMGIAHGMIVVHENNIIHRDLKTANILMDEHLLPKICDFGIARFEGIG------ESNLMTAG--IGT--SIY--MAPELYATRTYS
.    |.. .| ...  || ||   |..|.||||| . |.| .| .  ||.||| .|. . .      ..  ....   |     .  ||||   .....
HRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

NKVDVYSYAFILWEMSEK-KRAFAT-----IKPEKLHEKIYQKGERETFSMQ--------TPRALQTLIKKCWDADPSKRPSFQNIYNAF
 | ||.|.   .||.    .          .... ..|.. ..|.|               | .. ...|.||..||..||.|..|.  |
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYV-KQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 88546.m00247.AA STE 34-288 20 9.7e-34 116.55 In-house 1-359 (359) Show / Hide 
Range on Protein: 34-288
Range on HMM: 1-359/359
Sequence Identity: 20% (74 aa)

YEIQNTIGKGGFGEVNLARYTK---------------DGNLYAVKQIF-----------EKRLHG------NAFRRFLDEVKTMAKCL--DDFLLPISGF
.|..  ||||.||.| .|.. |                |...|.||.            |.          . . ..| |.|.| ||    ..     | 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQEN-Q-ELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGC

TFTAP--------YSIITPYIPSGCLKDYVSKKSAVKLT------------PTQLTKIAMGIAHG-MIVVHENNIIHRDLKTANILMDEHLLPKICDFGI
 |             |.  |.. |.| | . .|  .. .             .|. .|.  | .| .   |...|||||.| ||||.      |.||||.
YFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGV

AR-FEGIGE------------SNL-MT-AGIGTSIYMAPELYAT------RTYSNKVDVYSYAFILWEMSEKKRAFATIKPEKLHEKIYQK---------
.  .. ..             ..  ..   .||  .||||            |. |.|..|    ..|| . |  ... .| .    | ..         
CGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQ

-----GERETFSMQTP-------------------RALQTLIKKCWDADPSKRPSFQNIYN---AFA
     |.  ..   .                      ..  |.|| . ||.|||. .   .    | 
LCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 88546.m00247.AA Pkinase_Tyr 34-287 27 2.7e-33 113.39 Pfam 1-270 (270) Show / Hide 
Range on Protein: 34-287
Range on HMM: 1-270/270
Sequence Identity: 27% (76 aa)

YEIQNTIGKGGFGEVNLARYT----KDGNLYAVKQIFEKRLHGNA--FRRFLDEVKTMAKC-LDDFLLPISGFTF--TAP--YSIITPYIPSGCLKDYVS
 ..  ..|.| |||| .....    ...   ||| .     .  .   . |. |.|.| .    . ..   |       |  . |...| | |.|.||  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

KK--SAVKLTPTQLTKIAMGIAHGMIVVHENNIIHRDLKTANILMDEHLLPKICDFGIARFE-GIGES-NLMTAGIGTSI-YMAPELYATRTYSNKVDVY
|.  .  .||. .| .... || ||   ...|.||||| . |.| .| .  |||||| ||     ..     . |    |  ||||  ... .. | ||.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTKSDVW

SYAFILWEMSE-KKRA-FATIKPEKLHEKIYQKGERETFSMQTPRALQTLIKKCWDADPSKRPSFQNIYNAF
|.   .||.    .   .. ...| . |.||..|.|    . .|  . .|.|.||..||..||.|. |.. .
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 88546.m00247.AA Dicty4 34-48 60 0.000489 9.55 In-house 1-15 (277) Show / Hide 
Range on Protein: 34-48
Range on HMM: 1-15/277
Sequence Identity: 60% (9 aa)

YEIQNTIGKGGFGEV
. |.. ||||.||||
INIEQRIGKGSFGEV
Kinase 88546.m00247.AA LRRK 34-70 34 0.009165 5.59 In-house 1-36 (351) Show / Hide 
Range on Protein: 34-70
Range on HMM: 1-36/351
Sequence Identity: 34% (13 aa)

YEIQNTIGKGGFG-EVNLARYTKDGNLYAVKQIFEKRL
 .|.. ||.|||| .|  |..   |.  .|.... |.|
LKIEEQIGRGGFGTFVYRAKWR--GQPVHVCRMHQKML
Kinase 88546.m00247.AA HH498 34-53 35 0.009195 4.14 In-house 1-20 (284) Show / Hide 
Range on Protein: 34-53
Range on HMM: 1-20/284
Sequence Identity: 35% (7 aa)

YEIQNTIGKGGFGEVNLARY
 | . .|| | ||.| . ..
IEFHEKIGSGSFGKVYKGEW