Gene 89650.m00187 (T.vaginalis)

89650.m00187

Species: T.vaginalis
Alias: 89650.m00187, TvagK0202
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
89650.m00187.AA Protein None 310 None Fasta, JSON
89650.m00187.kin_dom Protein Kinase Domain None 280 None Fasta, JSON

Protein domain

Protein domains of 89650.m00187.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 89650.m00187.AA S_TKc 14-269 28 7.6e-72 245.92 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-269
Range on HMM: 1-231/231
Sequence Identity: 28% (77 aa)

YEIVKMIGKGGSGYCYLVKSLKFNQEFVCKVTKCANVDPKIIESHKSEAQILSNLNHPNIVRIYDYFIESNIVFQILEYCSG--GSLIDLIKSNEK----
|||.. ||||. | .|...  | .... .|. |         |. ..| |||.. .|||||..||.| . . .. ..|||.|  |.| |.||.. .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LSSNKKNKIFLEIVDALVFMHQKGIAHCDIKLSNILLDQFGRVKICDFGLSHLISKSKTLKCDKSVRGTMNYMSPEILLGIDYDPFMADVWAVGVTFY
  ..     ... .|..|| ..|..|| |.|.| .|||||.  ..|||||||. ..         ... || .||.||.|    |... .|.|..|...|
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

TLVTGQFPYGSYSSNTILNEIDAGHTKLDPKYGPMSEIVNWCMKIEPQHRPTMSQLQS-----KMVELF
 ...|. |.     ..... |            .. .... |.. .|..|||  ..       |. . |
EMLCGYPPFP--QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 89650.m00187.AA CAMKL 14-263 25 1.7e-60 191.75 In-house 1-293 (297) Show / Hide 
Range on Protein: 14-263
Range on HMM: 1-293/297
Sequence Identity: 25% (76 aa)

YEIVKMIGKGGSGYCYLVKSLKF-NQEFVCKVTKCANVD-PKIIESH------------KSEAQILSNLN---HPNIVRIYDYFIESNI------VFQIL
|.|.| .|||. |   | .  .. ...   |. .        .....            . |.||.. ||   ||||...|. .  ..       .. ..
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCSGGS--LIDLIKSN----EKLSSNKKNKIFLEIVDALVFMHQKGIAHCDIKLSNILLDQFG--RVKICDFGLSHLISK--SKTLKCDKSVRGTMNYM
||||||.  | | |...    .... .   ..|  ||.|. ..|..||.| |||. |||||. |   .||.|||.| .. .   .. .  |   |. .||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

SPEILLG--IDYDPFMADVWAVGVTFYTLVTGQFPYGSYS-------SNTILNEIDAGHTKLDPKYGPM---SEIVNWCMKIEPQHRPTMSQLQS
.|||..|   .|| . .|.|. ||. |..|.|..|    .        .  | ... .. . .|..  .     .  . ..  | .|||. |. .
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMN
Kinase 89650.m00187.AA MARK 14-261 30 1.2e-59 193.72 In-house 1-256 (262) Show / Hide 
Range on Protein: 14-261
Range on HMM: 1-256/262
Sequence Identity: 30% (79 aa)

YEIVKMIGKGGSGYCYLVKSLKFNQEFVCKVTK-CANVDPKIIESHKSEAQILSNLNHPNIVRIYDYFI--ESNI-VFQILEYCSGGSLIDLIKSN--EK
|...| ||.|. .  .|. ... ....  |. .     ||. ... ..|..|.. |.||||.. ....   ...  .. |.||.|||.| | ||.    .
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LSSNKKNKIFLEIVDALVFMHQKGIAHCDIKLSNILLDQFG--RVKICDFGLSHLISKSKTLKCDKSVRGTMNYMSPEILLGIDYDPFMADVWAVGVTFY
|. .   .||  || |. ..|.|.|.|.|||. |||.|. |   .||.|||.|  |   . |   ..  ||  ||.|||.|. .|| . .|.|. ||  |
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKL---NTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLY

TLVTGQFPYGSYS--SNTILNEIDAGHTKLDPKYGPMSE----IVNWCMKIEPQHRPTMSQL
..|.|.||.  ..   ...  .| .|. .  | .  .|     .... ... |  |||....
FMVCGYFPFDGDTQDYKELYKKILRGKYD-IPCH--VSKECRNLIQRLLTVNPEERPTIEEI
Pkinase 89650.m00187.AA Pkinase 14-265 25 2.2e-59 208.39 Pfam 1-293 (293) Show / Hide 
Range on Protein: 14-265
Range on HMM: 1-293/293
Sequence Identity: 25% (76 aa)

YEIVKMIGKGGSGYCYLVKSLKFNQEFVCKVTKCANVDPKIIESHKS--EAQILSNLNHPNIVRIYDYFIESNIVFQILEYCSGG----SLIDLIK--SN
|.|.. ||.|..| .|. .  . ......|. |  . ...  ..|    |.||. .||||||||.||.| ... .  ..||| ||    .| |.|.  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

EKL--SSNKKNKIFLEIVDALVFMHQKGIAHCDIKLSNILLDQFGRV----KICDFGLSHLISKSKTLKCDKSVRGTMNYMSPEILLGIDYDPFMADVWA
 ..  | .   .....|. .| ..|..|| |.|.|..|||.|. | .    |||||||. ...        ... || .||.||...|  |..  .|.|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

VGVTFYTLVTGQFPYGSY------SSNTILNEIDAGHTKLDPKYG----------------------PMSEIVNWCMKIEPQHRPTMSQLQSK--M
.|...| ...|..|. .       . . ....|  . .. |  .                       .. ....|| .  |. |||  |.     .
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 89650.m00187.AA CAMK 19-260 16 7.2e-58 184.71 In-house 1-418 (425) Show / Hide 
Range on Protein: 19-260
Range on HMM: 1-418/425
Sequence Identity: 16% (68 aa)

MIGKGGSGYCYLVKSLKFN------------QEFVCKVTKCA--------------------------NVDPKIIESHKSEAQILSN-------LNHPNI
 .|.|. |  .|..  . .            |.. .|. .                            ...||  .. ..| .|...       |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRIYDYFIESNI-------------------VFQIL---EYCSGG----SLIDLIKSNEK---------------LSSNKKNKIFLEIVDALVFMHQKGI
...|...  ..                    .. ..   ||||||     | | |.....               ..     ..|  |..|. ..|...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

AHCDIKLSNILLDQF-----------------GRVKICDFGLSHLISKSKTLKCD---------------------KSVRGTMNYMS-PEILLG------
.|.|.|. |||||.                  . .||.|||..  . ... ....                     | . ||  ||. ||.|.|      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------IDYDPFMADVWAVGVTFYTLVTGQFPYGSY-------------SSNTILNEIDAGHTKLDPKY-------------------------GPMSE
       ..|... .|.|..||  |....| .|. .              . . ..  | .|    .|.|                              
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

IVNWCMKIEPQHRPTMSQ
 ...... .|..|.| .|
LIRKMLQVDPEKRMTIEQ
Kinase 89650.m00187.AA Ciliate-E2 14-261 21 1e-52 179.25 In-house 1-359 (365) Show / Hide 
Range on Protein: 14-261
Range on HMM: 1-359/365
Sequence Identity: 21% (82 aa)

YEIVKMIGKGGSG-----YCYLVKSL-----------------KFN-QEFVCKVTKCANVDPKIIESHKS-----------EAQILSNLNHPNIVRIYDY
|...|.||.|. |       ..|. .                 |.. ...  |. |  ..  .  | |             | .||..||||||...|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FI---ESNIVFQILEYCSGGSLIDLIKSN-----------EKLSSNKKNKIFLEIVD---------------ALVFMHQKG-IAHCDIKLSNILLDQFGR
|.   ..|| . ..|||.||.| |.||.|           .... ..  .|. .|..               || ..|.|. | | |||..|||.     
FQEKDDNNIYL-VMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

VKICDFGLSHLISKS----------KTLKCDKS--------------------VRGTMNYMSPEILLGIDYDP--------FMADVWAVGVTFYTLVTGQ
.||.|||||  ....          | ..  |.                    . || .||.|||| | .||         ...|.|..||..| ...|.
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

FPYGSYSSNTILNEIDAGHTKLDPK------YGPMSEIVNW--------------------CMKIEPQHRPT-MSQL
.|.        ...|  .  .....      . .  . ..|                    ... .|. |.| ..|.
PPF--------QQQIKQCKIDFPCPEWQKDTQ-CI-Q-CKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQI
Kinase 89650.m00187.AA STE 14-261 20 7.6e-50 171.92 In-house 1-351 (359) Show / Hide 
Range on Protein: 14-261
Range on HMM: 1-351/359
Sequence Identity: 20% (74 aa)

YEIVKMIGKGGSGYCYLVKSL------KFNQE---------FVCKVTK---------------CANVDPKIIESHKSEAQILSNLN--HPNIVRIYDYFI
.|....||||..|  |. .        | ...         .  |. .                 |........ . | .|....|  |||||. |....
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

ES-------NIVFQILEYCSGGSLIDLIKSN-EKLSSNKKNK-------------IFLEIVDA-LVFMHQKGIAHCDIKLSNILLDQFGRVKICDFGLSH
         . .. ..||..|||| |.||.. ... ....|.             |  .|. . | . |...| | ||| .||||     ||.||||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

LISKS--------------KTLKCDKSVRGTMNYMSPEILLG------IDYDPFMADVWAVGVTFYTLVTGQFPYGSYSSNTILNEIDAG----------
 ...|               . .  ... ||  .|.||....       .|| . .|.| .| |   ..||. |.  ..    . .|  .          
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYD-TKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

-----HTKLDPKY---------------------GPMSEIVNWCMKIEPQHRPTMSQL
     .    |                        .. . .| | ...|..||| |||
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQL
Kinase 89650.m00187.AA Ciliate-E2-Unclassified 14-226 23 8.9e-50 170.83 In-house 1-298 (352) Show / Hide 
Range on Protein: 14-226
Range on HMM: 1-298/352
Sequence Identity: 23% (72 aa)

YEIVKMIGKGGSGYCYLVKSLKFNQEF-----VCKVTKCA-----NVDPKIIESHKSEAQ---------------ILSNLNHPNIVRIYDYFIESNIVFQ
|.|.| ||.|| |  |...  | . ..      .|. ...     |.|  |. . | . .               ||.|..||.||. ...|   . .. 
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

ILEYCSGGSLIDLIKSNEK-----------------LSSNKKN-----KIFLEIVDALVFMHQKG-IAHCDIKLSNILLDQFG---RVKICDFGLSHLIS
..||| ||.|.. ||...|                 .. ..       ..| .|...| ..|.|. | | |||..|||.|. |   ..||.|||.|  . 
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

KSKTLKCDK--------------SVRGTMNYM----SPEILLGIDYDP---FMADVWAVGVTFYTLVTGQFPYGSYSSNT----------------ILNE
..   . ..              .. || |||    .||.| |  ||    ...|.|..|| .| ...|..|.......                 ....
QNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQN

I
|
I
Kinase 89650.m00187.AA TKL 20-265 19 6.5e-48 165.49 In-house 1-364 (364) Show / Hide 
Range on Protein: 20-265
Range on HMM: 1-364/364
Sequence Identity: 19% (72 aa)

IGKGGSGYCYLVKSLKFN--------QEFVCKVTKCANVDP-------------------------KIIESHKSEAQILSNLNHPNIVRIYDYFIESNI-
||.||.|  |  |    .        .. . |. |  |.|                          .. .  . |. ..|.|.|||||... | ....  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------VFQILEYCSGGS-LIDLIKSNEKLSSNKKNKIFLEIVDALVFMHQ--------KGIAHCDIKLSNILLDQFGR--------------V
             . . |||.||| | .|.        ... .. |.|  .. ..|.        ..|.|.|.| .|||.|. ..              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KICDFGLSHLISKSKTLKCDKS-----------------VRGTMNYMSPEILLGIDYDP---------------FMADVWAVGVTFYTLVTGQFPYG-SY
||||||||  .|.|.  .. ..                 ..|| ..|.||.| | ....                 .||.. |. .. ..|.. ||    
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

SSNTI---------LNEIDAGHTKLDP------------KYGP--MSEIVNWCMKIEPQHRPTMSQLQSKM
..  |            .| |.  . |            .. |  |...  .|.. .|. ||..... ...
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 89650.m00187.AA ULK 14-227 25 4.1e-47 162.51 In-house 1-273 (329) Show / Hide 
Range on Protein: 14-227
Range on HMM: 1-273/329
Sequence Identity: 25% (71 aa)

YEIVKMIGKGGSGYCYLVKSLKF----NQEFVCKVTK---CANVDPK-----IIESHKSEAQILSNLN--------HPNIVRIYDYFIESNI--VFQILE
|.. ...|||  |. |  .  |     |. ..||.     . .         .... |.| .|.  |.        |||||. ||.| .||   .. |.|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCSGGSLIDLIKSNEK----------LSSNKKNKIFLEIVDALVFMHQKGIAHCDIKLSNILLDQF------------GRVKICDFGLSHLISKS---KT
|| || | ..|| | |          || ..  ..|  |. .. ..|...| |.|||..|||..              |..||.|||..  ....   . 
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

LKCDKS----VRGTMNYMSPEILL----GIDYDPFMADVWAVGVTFYTLVTGQFPYGSYSSNTIL-----NEID
. .  .    ..||  ||.|.||     ...|. . .|.| .|. || ...|. |. ..  |.       ..|.
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLIN
Kinase 89650.m00187.AA ULK 14-227 27 2.3e-46 160.37 In-house 1-268 (324) Show / Hide 
Range on Protein: 14-227
Range on HMM: 1-268/324
Sequence Identity: 27% (75 aa)

YEIVKMIGKGGSG-YCYLVKSLKF---NQEFVCKVTKCANVDPK--------IIESHKSEAQILSNLN---HPN--IVRIYDYFIESNI--VFQILEYCS
|.. ...|||  | . |  .  |    || . ||.    .   |        .... |.| ||.  |.   |||  ||. ||.| .||   .. |.||| 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGSLIDLIKSNEK---------LSSNKKNKIFLEIVDALVFMHQKGIAHCDIKLSNILLDQF------------GRVKICDFGLSHLISKSKTLKCD-KS
|| | ..|| | |         || ..  ..|  |. .. ..|...| |.|||..|||.               |..||.|||..  . .    ... ..
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

VR------GTMNYMSPEILL----GIDYDPFMADVWAVGVTFYTLVTGQFPYGSYSSNTIL----NEID
        ||  ||.|.||     ...|. . .|.| .|. || ...|. |. |.  |.      ..|.
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLIN
Kinase 89650.m00187.AA RSK 17-263 24 4.5e-43 149.43 In-house 1-274 (278) Show / Hide 
Range on Protein: 17-263
Range on HMM: 1-274/278
Sequence Identity: 24% (69 aa)

VKMIGKGGSGYCYLVKSL---KFNQEFVCKVTKCANVDPKI--IESHKSEAQILSNLN-HPNIVRIYDYFIESNIVFQILEYCSGGSLIDLIKSNEK---
.|. |.|| |  .|..     . .|..  || | | ....   ..  . | .||.  . ||.||. .. | .   .. |.|||.|| | . ..  .    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LSSNKKNKIFLEIVDALVFMHQKGIAHCDIKLSNILLDQ---FGRVKICDFGLSHLISKSKTLKCD-----KSVRGTMNYMSPEILL----GIDYDPFMA
.| .    .. ||| |. ..||.|| | |.|..|||.|.    |..|..|||.. .       .||     .. ..| .|| ||.|     .  .|   .
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF------RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDK-AC

DVWAVGVTFYTLVTGQFPYGS---YSSNTILNEIDAGH--TKLD--PKYGP-MSEIVNWCMKIEPQHRPT-----MSQLQS
|.|  ||  |.. ||. |. .    ... |.. |  |.   ...  ..  . . ........ .|. |..     ......
DWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQ
Kinase 89650.m00187.AA TyrKc 14-265 21 3.9e-16 38.13 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-265
Range on HMM: 1-280/280
Sequence Identity: 21% (65 aa)

YEIVKMIGKGG-----SGYCYLVKSLKFNQEFVCKVTKCANVDPKIIESHKSEAQILSNL--NHPNIVRIYDYFIES-------NIVFQILEYCSGGSLI
 .  |..| |       |  .        ..   |. |        .|   .||.|...|  .||||||.| . ...         .. ..||...|.| 
ITLGKKLGEGAFGEVYKGTWK--------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLK

DLIKSNEK-LSSNKKNKIFLEIVDALVFMHQKGIAHCDIKLSNILLDQFGRVKICDFGLSHLISKS-------KTLKCDK--SVR--GTMNYMSPEILLG
| ...... |.  .. .. . | .   . |.|.. | |.   |.|..  ..|||.|||||  |          .. .  .  . .       |.|| .  
DYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--

IDYD--PFMADVWAVGVTFYTLVT-GQFPYGS-----YSSNTILNEIDAGHTKLDPKY----------GPMSEIVNWCMKIEPQHRPTMSQLQSKM
 .|    .  |||. ||. . . | || ||        |   ... ...|.    |..            | .|  .| . .|  |||.|.. ...
-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 89650.m00187.AA Pkinase_Tyr 60-158 28 9.7e-12 40.38 Pfam 52-158 (270) Show / Hide 
Range on Protein: 60-158
Range on HMM: 52-158/270
Sequence Identity: 28% (31 aa)

SEAQILSNL-NHPNIVRIYDYFI-ESNI--VFQILEYCSGGSLIDLIKS----NEKLSSNKKNKIFLEIVDALVFMHQKGIAHCDIKLSNILLDQFGRVK
.||.|...| .|||||| |   . ..    .. ..||. .|.| |  ..    ...|.   . .. ..| ... . ..|.. | |.   |.|..  . ||
REAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVK

ICDFGLS
||||||.
ICDFGLA
Kinase 89650.m00187.AA Pkinase_Tyr 247-265 31 0.00057 14.07 Pfam 252-270 (270) Show / Hide 
Range on Protein: 247-265
Range on HMM: 252-270/270
Sequence Identity: 31% (6 aa)

CMKIEPQHRPTMSQLQSKM
|.. .|..|||.|......
CWHYDPEDRPTFSEIHEQL