Gene 84404.m00103 (T.vaginalis)

84404.m00103

Species: T.vaginalis
Alias: TvagK0172, 84404.m00103
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
84404.m00103.AA Protein None 300 None Fasta, JSON
84404.m00103.kin_dom Protein Kinase Domain None 247 None Fasta, JSON

Protein domain

Protein domains of 84404.m00103.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 84404.m00103.AA CAMKL 61-203 32 4.2e-53 167.72 In-house 62-225 (297) Show / Hide 
Range on Protein: 61-203
Range on HMM: 62-225/297
Sequence Identity: 32% (53 aa)

EAEILSKLN---HPNIVRIYDYFIEQDI------SFIILEYCSNGS--LLDLVKTQ----KRITQEKINKYTLQIVDALSFMHSKGIAHCDIKLSNILID
|..|...||   ||||...|. .  ..        ....||||.|.  |.| .. .    .|.. .   .|  |||.|....||.||.| |||. |||.|
EIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLD

QYD--RAKLCDFGLSHYITN--DSNKINDNKIRGTLNYMAPEVIIG--KEFCPFKSDVWSFGVT
. .   .|..|||.| ....  . .    .   |...|||||.. |  |... .| |.|| ||.
ENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVI
Kinase 84404.m00103.AA CAMK 61-254 19 7.5e-52 164.98 In-house 81-420 (425) Show / Hide 
Range on Protein: 61-254
Range on HMM: 81-420/425
Sequence Identity: 19% (66 aa)

EAEILSK-------LNHPNIVRIYDYFIEQDI-------------------SFIIL---EYCSNG----SLLDLVKTQ---------------KRITQEK
| ||..|       |.||||...|...   .                     ....   ||||.|     |.| .. .               .|.| . 
EIEIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTERE

INKYTLQIVDALSFMHSKGIAHCDIKLSNILIDQYD-----------------RAKLCDFGLSHYITNDSNKINDNK---------------------IR
  .|  ||..|. ..||..|.|.|.|. |||.|. .                   |..|||.. ... ..|  ....                       
ARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFC

GTLNYMA-PEVIIG-------------KEFCPFKSDVWSFGV--------TFPFISR-------------DPFTILRDIKNGYIK-IFPRYGP-------
||. ||| |||. |             |. ...|.|.|| ||        ..|| .              ..  ... |..|    . |   |       
GTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGP

-----------------LARIADQCLNLDPLERPTMAQIK
                       ..|. || .|.| .|..
EWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCL
S_TKc 84404.m00103.AA S_TKc 14-258 26 1e-50 175.7 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-258
Range on HMM: 1-231/231
Sequence Identity: 26% (71 aa)

YEIVKYLDHDSYRSCFLIKSLKYDMNFVCKVSRTTDLPQEYLASFYGEAEILSKLNHPNIVRIYDYFIEQDISFIILEYCSN--GSLLDLVKTQKR----
|||.. . . .. .... .  | .  . .|. .          ... | .||.| .|||||..||.| . |  ....|||..  |.|.|. | ..|    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--ITQEKINKYTLQIVDALSFMHSKGIAHCDIKLSNILIDQYDRAKLCDFGLSHYITNDSNKINDNKIRGTLNYMAPEVIIGKEFCPFKSDVWSFGVTF-
  ..   . .|. ||..|| ..||.|| |.|.| .|||.|.  . |.|||||.  .         . . ||..||||||.    . ..|.|.||.|... 
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

-------PFISRDPFTILRDIKNGYIKIFPRYGPLARIADQCLNLDPLERPTMAQIK--------FKIY
       ||   ....... |.           ..  . ..||. || .|||  ..             
EMLCGYPPFP--QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 84404.m00103.AA Pkinase 61-204 37 8e-46 163.1 Pfam 50-202 (293) Show / Hide 
Range on Protein: 61-204
Range on HMM: 50-202/293
Sequence Identity: 37% (58 aa)

EAEILSKLNHPNIVRIYDYFIEQDISFIILEYCSNG----SLLDLVK--TQKRI--TQEKINKYTLQIVDALSFMHSKGIAHCDIKLSNILIDQYDRA--
|..|. .||||||||.||.| . |   ...||| .|    .| |...   ....  . . . .| .||. .| ..||.|| |.|.|..|||||. .    
EIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA

--KLCDFGLSHYITNDSNKINDNKIRGTLNYMAPEVIIGKEFCPFKSDVWSFGVTF
  |.|||||.  .    |.   . . ||..||||||| | .  . |.|.||.|...
CVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCIL
Kinase 84404.m00103.AA STE 61-252 24 3.1e-45 156.59 In-house 78-350 (359) Show / Hide 
Range on Protein: 61-252
Range on HMM: 78-350/359
Sequence Identity: 24% (69 aa)

EAEILSKLN--HPNIVRIYDYFIEQ-------DISFIILEYCSNGSLLDLVK----TQK----------RITQEKINKYTLQIVDA-LSFMHSKGIAHCD
| .|..|.|  |||||. |....         |  .|..||...||| |..|    ..|          |.  . | ... ||. . |.. ||..| | |
EIKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRD

IKLSNILIDQYDRAKLCDFGLSHYITND--------------SNKINDNKIRGTLNYMAPEVIIGKEFCPF------KSDVWSFGVTF-------PFISR
|| .|||.     .||||||..  .|..              ... . | . ||  .|||||| . . .        |.|.||.| |        |  . 
IKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDTKCDIWSLGCTIIEMATGKPPWHD

DPFT--ILRDIKN--------------GYIKIFPRY---------------------GPLARIADQCLNLDPLERPTMAQ
 . .  ... ..|              | .  .|                        ..    ..||. || .|||  |
MHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ
Kinase 84404.m00103.AA ULK 61-204 28 1.3e-44 154.53 In-house 60-242 (324) Show / Hide 
Range on Protein: 61-204
Range on HMM: 60-242/324
Sequence Identity: 28% (53 aa)

EAEILSKLN---HPN--IVRIYDYFIEQDI--SFIILEYCSNGSLLDLVK---------TQKRITQEKINKYTLQIVDALSFMHSKGIAHCDIKLSNILI
| .|. ||.   |||  ||. ||.| ...    .||.|||  | | .. |         ..||...... ..  ||. .. ..|...| |.|||..||||
EIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILI

DQYD------------RAKLCDFGLSHYITNDSNKINDN-------KIRGTLNYMAPEVII----GKEFCPFKSDVWSFGVTF
   .            ..|..|||..  . |..   ...       .|.||  ||||...     .|... .|.|.||.|. |
HNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIF
Kinase 84404.m00103.AA ULK 63-204 28 1.3e-44 153.67 In-house 62-246 (329) Show / Hide 
Range on Protein: 63-204
Range on HMM: 62-246/329
Sequence Identity: 28% (52 aa)

EILSKLN--------HPNIVRIYDYFIEQDI--SFIILEYCSNGSLLDLVK----------TQKRITQEKINKYTLQIVDALSFMHSKGIAHCDIKLSNI
.|. ||.        |||||. ||.| ...    .||.|||  | | .. |          ..||...... ..  ||. .. ..|...| |.|||..||
KIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNI

LIDQYD------------RAKLCDFGLSHYITND---SNKINDNK----IRGTLNYMAPEVII----GKEFCPFKSDVWSFGVTF
||.  .            ..|..|||..  ..||    . .   .    ..||  ||||...     .|... .|.|.||.|. |
LIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIF
Kinase 84404.m00103.AA Ciliate-E2 61-204 28 3.5e-43 146.09 In-house 82-286 (365) Show / Hide 
Range on Protein: 61-204
Range on HMM: 82-286/365
Sequence Identity: 28% (60 aa)

EAEILSKLNHPNIVRIYDYFI--EQDISFIILEYCSNGSLLDLVKTQ-----------KRITQEKINKYTLQIVD---------------ALSFMHSKG-
| .||..||||||...|..|.   ..  ....|||. |.|.|. | .           |..| ..| ... ||..               || ..|||. 
EKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN

IAHCDIKLSNILIDQYDRAKLCDFGLSHYITND---------SNKINDNK---------------------IRGTLNYMAPEVIIGKEF--------CPF
| | |||..|||.      |..||||| ....|         .... . |                     | ||..|||||.. ||.           .
IIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDY

KSDVWSFGVTF
|.|.||.||..
KCDIWSLGVIL
Kinase 84404.m00103.AA MARK 61-202 38 2.1e-42 136.5 In-house 49-194 (262) Show / Hide 
Range on Protein: 61-202
Range on HMM: 49-194/262
Sequence Identity: 38% (57 aa)

EAEILSKLNHPNIVRIYDYFI--EQDI-SFIILEYCSNGSLLDLVKTQ--KRITQEKINKYTLQIVDALSFMHSKGIAHCDIKLSNILIDQYD--RAKLC
|.||..||.||||.. ....   .     ..|.||.|.|.|.| .| .   |.. |   ..  ||| |....|||.|.|.|||. |||||.     .|..
EIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKII

DFGLSHYITNDSNKINDNKIRGTLNYMAPEVIIGKEFCPFKSDVWSFGV
|||.|  |....     |   ||. |||||.. .|. . .| |.|| ||
DFGFSICIPPGQK---LNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGV
Kinase 84404.m00103.AA TKL 61-202 24 2.1e-39 137.24 In-house 75-277 (364) Show / Hide 
Range on Protein: 61-202
Range on HMM: 75-277/364
Sequence Identity: 24% (51 aa)

EAEILSKLNHPNIVRIYDYFIEQDI-------------SFIILEYCSNGSLLDLVKTQKRITQEKINKYTLQIVDALSFMHS--------KGIAHCDIKL
|. ..|.|.|||||... | .. .               .|. |||..||||...        ... .  |.|  .....||        ..|.|.|.| 
EIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKS

SNILIDQYDR--------------AKLCDFGLSHYITNDSNKI-----------------NDNKIRGTLNYMAPEVIIGKEF---------------CPF
.|||.|.  .              .|.||||||  .....|.                  . ....||...|||||. |...                  
KNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSE

KSDVWSFGV
|.||.|||.
KCDVYSFGI
Kinase 84404.m00103.AA Ciliate-E2-Unclassified 63-204 28 2.2e-37 127.25 In-house 73-260 (352) Show / Hide 
Range on Protein: 63-204
Range on HMM: 73-260/352
Sequence Identity: 28% (53 aa)

EILSKLNHPNIVRIYDYFIEQDISFIILEYCSNGSLLDLVKTQ-----------------KRITQEKIN-----KYTLQIVDALSFMHSKG-IAHCDIKL
.||. ..||.||. ...|  ..  .|..||| .|.|..  | .                 |..| ...      .|. ||...|...|.|. | | |||.
QILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKP

SNILIDQYD---RAKLCDFGLSHYITNDSN-------------KINDNKIRGTLNYM----APEVIIGKEFCP---FKSDVWSFGVTF
.|||.|.     . |..|||.| .. ...|             . . . . ||.|||    ||||. |..      .|.|.||.|| .
ENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVIL
Kinase 84404.m00103.AA PLK-Unclassified 61-202 39 1.7e-33 117.59 In-house 49-196 (264) Show / Hide 
Range on Protein: 61-202
Range on HMM: 49-196/264
Sequence Identity: 39% (59 aa)

EAEILSKLNHPNIVRIYDYFIEQDISFIILEYCSNGSLLDLVKTQ-------KRITQEKINKYTLQIVDALSFMHSKGIAHCDIKLSNILIDQYDRAKLC
| .| . |.|.|||.... |  ..   | ||||.||.| .. |         ||.|      ||.||| ||  .|...| | | || ||...   . |.|
EIKIHKSLHHKNIVKFEHCFEDHENVYILLEYCPNGTLMEYIKRRNFQLFEKKRLTEYEVKCYTYQIVQALKYLHQNRIIHRDLKLGNIFLNDNMEVKIC

DFGLSHYITNDSNKINDNKIRGTLNYMAPEVIIGKE-FCPFKSDVWSFGV
||||.  ..||. | .   | || || |||.  ||.    ...|.||||.
DFGLATKLENDGEKKKT--ICGTPNYIAPEILDGKHQGHSYEVDCWSFGC
Pkinase_Tyr 84404.m00103.AA Pkinase_Tyr 54-203 32 1.5e-26 90.58 Pfam 46-203 (270) Show / Hide 
Range on Protein: 54-203
Range on HMM: 46-203/270
Sequence Identity: 32% (52 aa)

YLASFYGEAEILSKL-NHPNIVRIYDYFIEQDIS---FIILEYCSNGSLLDLVKT----QKRITQEKINKYTLQIVDALSFMHSKGIAHCDIKLSNILID
....|  ||.|...| .|||||| |   ..|. .   .|..||. .|.|||  ..    ....| . . .. .|| ..... .||.. | |.   |.|..
CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVT

QYDRAKLCDFGLSHYITNDSNK-INDNKIRGTLNYMAPEVIIGKEFCPFKSDVWSFGVT
    .| |||||. .|.||..      . .     ||||.|  .. .  |||||||||.
ENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSDVWSFGVL
TyrKc 84404.m00103.AA TyrKc 14-257 23 3.4e-23 84.3 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-280/280
Sequence Identity: 23% (69 aa)

YEIVKYLDHDSY---RSCFLIKSLKYDMNFVCKVSRTTDLPQEYLASFYGEAEILSKL--NHPNIVRIYDYFIEQ-------DISFIILEYCSNGSLLDL
 .  | | .  .   . . ..      ..   |. .        .. |. ||.|..||  .||||||.| . ..|       .  .|..||...|.|.| 
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

VKTQKR-ITQEKINKYTLQIVDALSFMHSKGIAHCDIKLSNILIDQYDRAKLCDFGLSHYITND-----SNKINDN----KIR--GTLNYMAPEVIIGKE
 .  .. .. ..  .. .|| .  .. |||.. | |.   |.|..   ..| .||||| .|..|     | .  .       .    .  ||||.|  ..
LRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NY

F-CPFKSDVWSFGVT---------FPFIS-----RDPFTILRDIKNGYIKIFPRY----------GPLARIADQCLNLDPLERPTMAQIKFKI
  . .|||||||||.          |         ... .....|.||    | .            . .|  || . || .|||...|. ..
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 84404.m00103.AA TKL 231-257 22 7.5e-05 13.42 In-house 338-364 (364) Show / Hide 
Range on Protein: 231-257
Range on HMM: 338-364/364
Sequence Identity: 22% (6 aa)

PLARIADQCLNLDPLERPTMAQIKFKI
...... .| . || .||.. .|. ..
SMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 84404.m00103.AA Pkinase_Tyr 238-257 40 0.007009 10.38 Pfam 251-270 (270) Show / Hide 
Range on Protein: 238-257
Range on HMM: 251-270/270
Sequence Identity: 40% (8 aa)

QCLNLDPLERPTMAQIKFKI
|| . || .|||...|  ..
QCWHYDPEDRPTFSEIHEQL
Kinase 84404.m00103.AA PLK-Unclassified 240-259 40 0.099894 2.75 In-house 245-264 (264) Show / Hide 
Range on Protein: 240-259
Range on HMM: 245-264/264
Sequence Identity: 40% (8 aa)

LNLDPLERPTMAQIKFKIYQ
||..| .|||. ||.   . 
LNWNPDQRPTIDQIMMHPFY
Kinase 84404.m00103.AA CAMKL 240-254 46 0.190173 0.21 In-house 278-292 (297) Show / Hide 
Range on Protein: 240-254
Range on HMM: 278-292/297
Sequence Identity: 46% (7 aa)

LNLDPLERPTMAQIK
|. .| .|||. ||.
LQVNPEKRPTIHQIM
Kinase 84404.m00103.AA Pkinase 237-257 39 0.404533 5.04 Pfam 271-293 (293) Show / Hide 
Range on Protein: 237-257
Range on HMM: 271-293/293
Sequence Identity: 39% (9 aa)

DQCLNLDPLERPTMAQIKFK--I
. ||..|| .||| .||.    .
KWCLCKDPKKRPTAEQILQHPWF