Gene 85686.m00167 (T.vaginalis)

85686.m00167

Species: T.vaginalis
Alias: 85686.m00167, TvagK0047
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
85686.m00167.AA Protein None 302 None Fasta, JSON
85686.m00167.kin_dom Protein Kinase Domain None 260 None Fasta, JSON

Protein domain

Protein domains of 85686.m00167.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 85686.m00167.AA CAMKL 7-266 31 7.1e-101 322.66 In-house 1-297 (297) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-297/297
Sequence Identity: 31% (95 aa)

YEPRRFLGAGSFGGVWECQN-KTTGESVACKLIDLNTALSDKVYPHF------------RNEILIHSKIN---HPSVTQLKDVILDNDN------VYIFL
|.  . || |||| |  ... .|||| || | || . .  | .                | || |....|   || . .| .|| . ..      .|...
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELCDGGD--MNDIVQEFGG----LSEDEAEHYFHQIMEALSYIHKLGVAHRDVKLENILVTADDD--AKLTDFGLCKQQH-G----NDPMLTTCGTLVYA
|.|.||.  . | ... |.    ..|.|| .|| ||..|..|.|..|..||| |.||||.. ...  .|..|||.. ..  .    .. . | ||.. |.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEIIQE--KPYNGMKADIWSAGVVLYAMVAAHFPWIVPDD---MPPENIMKETARQIVEGDIALPDGISYELQNLMANLLNVDPNERPTAAEVLEHPWF
||||.|   |||.| |.||||.||.|||||  ..|.  ...       .  ..    .  . .  .  .| ....|   .|.|.|..|||. ....|||.
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 85686.m00167.AA CAMK 12-266 24 3e-100 323.74 In-house 1-425 (425) Show / Hide 
Range on Protein: 12-266
Range on HMM: 1-425/425
Sequence Identity: 24% (102 aa)

FLGAGSFGGVWECQNK-TTG-----------ESVACKLIDLNTALS-------------------------DKVYPHFRNEILIHSK-------INHPSV
 || |||| | .|..| |||           . ||.| || . . .                         .|    .|.|| |..|       ..|| .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

TQLKDVILD-------------------NDNVYIFL---ELCDGG----DMNDIVQEFGG---------------LSEDEAEHYFHQIMEALSYIHKLGV
 .| .|. |                   ....|...   |.|.||    |. | ..| |.               ..|.|| .||.|| .|. |.|....
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

AHRDVKLENILVTADD-----------------DAKLTDFGLCKQQHG------------------------NDPMLTTCGTLVYAA-PEIIQE------
.||| |.||||.. ..                 . |..|||. ..  .                        ...| | |||. |.| ||...       
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------KPYNGMKADIWSAGVVLYAMVAAHFPWIVPDDMPPEN------IMKETARQIVEGDIALP----------------DGISYE--------LQN
       ||| | |.|.||.||.||.|.  ..|.  ..|.  ..       ..|. ..| .|.   |                |.|| |         ..
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LMANLLNVDPNERPTAAEVLEHPWF
|  ..|.|||..|.|....|.|||.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 85686.m00167.AA S_TKc 7-266 35 1.5e-93 317.99 SMART 1-231 (231) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-231/231
Sequence Identity: 35% (97 aa)

YEPRRFLGAGSFGGVWECQNKTTGESVACKLIDLNTALSDKVYPHFRNEILIHSKINHPSVTQLKDVILDNDNVYIFLELCDG--GDMNDIVQEFGG---
||  | .| |.|| |. |..| ||. ||.| |.           |.|.|| |..| .|| . .|.||. | |..|...|.|||  ||. |. .. |.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LSEDEAEHYFHQIMEALSYIHKLGVAHRDVKLENILVTADDDAKLTDFGLCKQQHGNDPMLTTCGTLVYAAPEIIQEKPYNGMKADIWSAGVVLYAM
   ..| .| .|..|| .|| |.|..|. |||.| ||||..     |..||||..|        | |||. | |||..   .|.. |.|.|| |..|| |
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

VAAHFPWIVPDDMPPENIMKETARQIVEGDIALPDGISYELQNLMANLLNVDPNERPTAAEVLE-------HPWF
..   |.           |... ..|.          | |. ... ..|..||..|||| |.|.       ||||
LCGYPPFP---------QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 85686.m00167.AA Pkinase 7-266 33 8.4e-88 302.8 Pfam 1-293 (293) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-293/293
Sequence Identity: 33% (99 aa)

YEPRRFLGAGSFGGVWECQNKTTGESVACKLIDLNTALSDKVYPHFR-NEILIHSKINHPSVTQLKDVILDNDNVYIFLELCDGG----DMNDIVQ--EF
|.  | .|.|||| |..|..| ||. ||.| |.. .. |.| . |.| .|| |. ..||| . .|.|.  |.|..|. .|.|.||    |  |...  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GGL--SEDEAEHYFHQIMEALSYIHKLGVAHRDVKLENILVTADDDA----KLTDFGLCKQ--QHGNDPMLTTCGTLVYAAPEIIQEKPYNGMKADIWSA
|..  ||.|. .|. || ..| |.|. |. |||.|.||||.  ...     |..||||.||     |  | | |||. |.|||.|.. .| | |.|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVVLYAMVAAHFPWIVPD-DMPPENIMKETARQIVEGDIALPDGIS---------------------YELQNLMANLLNVDPNERPTAAEVLEHPWF
|..|| |.  ..|.   . . .. . ...  ..| ....  .   .                      |.. .. ..|..||..||||...|.||||
GCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 85686.m00167.AA MARK 7-266 36 9.9e-85 276.89 In-house 1-262 (262) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-262/262
Sequence Identity: 36% (98 aa)

YEPRRFLGAGSFGGVWECQNKTTGESVACKLIDLNTALSD-KVYPHFRNEILIHSKINHPSVTQLKDVIL--DNDN-VYIFLELCDGGDMNDIVQEF--G
|.  . .| ||.. |  ...| ||. || | ..  . |.| .    .. || |..|..|| ...| .||   .. . .|. .|.. ||.. | ....  |
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEK-FKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNG

GLSEDEAEHYFHQIMEALSYIHKLGVAHRDVKLENILVTADD--DAKLTDFGLCKQQHGNDPMLTTCGTLVYAAPEIIQEKPYNGMKADIWSAGVVLYAM
 |.|.|| ..|.|| .|..| |. ...||| |.||||. ..   ..|..|||.. .   .    | |||. |.||||.. |||.| |.|||| |||||.|
RLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM

VAAHFPWIVPDDMPPENI--MKETARQIVEGDIALPDGISYELQNLMANLLNVDPNERPTAAEVLEHPWF
|  .||.        .    .||  ..|. |.   |. .| |..||   ||.|.|.||||. |...|||.
VCGYFPFD-------GDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 85686.m00167.AA AMPK 7-266 34 4.6e-73 216.26 In-house 1-254 (254) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-254/254
Sequence Identity: 34% (89 aa)

YEPRRFLGAGSFGGVWECQNKTTGESVACKLIDLNTALSDKVYPHFRNEILIHSKINHPSVTQLKDVI-LDNDNVYIFLELCDGGDMNDIVQEFGGLSED
|     .| |.|| |     ..||| || | ..     ....    ..|| |  ...||...|| .||   ..  ....|   ||.  | .   | |.|.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EAEHYFHQIMEALSYIHKLGVAHRDVKLENILVTADDDAKLTDFGLCKQQHGNDPMLTTCGTLVYAAPEIIQEKPYNGMKADIWSAGVVLYAMVAAHFPW
||  .| ||  ...|.|.....||| |.||.|  ..   |. |||| .    ..   | ||   |||||.|. |.|.| . |||| ||.||||. .  | 
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

IVPDDMPPENIMKETARQIVEGDIALPDGISYELQNLMANLLNVDPNERPTAAEVLEHPWF
   ||    .  |     |..|.  .|. .| | ..|. ..|.|||..| |  .. .||||
---DDENTPTLYK----KIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 85686.m00167.AA Ciliate-E2 7-266 22 8.8e-68 231.5 In-house 1-365 (365) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-365/365
Sequence Identity: 22% (89 aa)

YEPRRFLGAGSFGGVWECQNKTTGESVACKLIDLNTALSD--------------KVY-----PHFRNEILIHSKIN----------------HPSVTQLK
|.  . .| |.|| |..|... ... .| |.|| .   ..              |..      .. .|| |  .||                || . ...
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQ-QRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMY

DVIL--DNDNVYIFLELCDGGDMNDIVQEF-----------GGLSEDEAEHYFHQIME---------------ALSYIHKLG-VAHRDVKLENILVTADD
..    |..|.|. .|.|.|||. |. ...           . ..| |. ... || .               || |.|. . . ||| |.||||.    
ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

DAKLTDFGLCKQQHGNDPMLT--------------------------------TCGTLVYAAPEIIQEKPYNG--------MKADIWSAGVVLYAMVAAH
  |..||||.|... .  . |                                .|||. | ||||.. |.|..         |.||||.||.|| |.   
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

FPWIVPDDMPPENIMKETARQIVEGDIALP------------------DGISYELQNLMAN----LLNVDPNERPT-AAEVLEHPWF
.|.                .|| ...| .|                  . .| | ..|. .    .|..||..|.| . ..|.||||
PPF---------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 85686.m00167.AA CAMK-Unique 7-266 26 5.3e-66 216.8 In-house 1-363 (363) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-363/363
Sequence Identity: 26% (96 aa)

YEPRRFLGAGSFGGVWECQNKTTGESVACKLIDLNTALSDKVYP-----------------HFRNEILIHSKINHPSVTQLKDV----ILDND-------
|.  | .| |.|| | ||....||   |||.. . |. ..| ..                  ...|. |  . .||   .| |.     .| .       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------NVYIFLELCDGGDMNDIVQE--------------------FGGLSE--DEAEHYFHQIMEALSYIHKLGVAHRDVKLENILVTAD--D----
        . ||..|.|.|||..|..|.                     | .||   ..  .. .. .|..| |.... ||| |||||.|     |    
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

----------DAKLTDFGLCKQQHGNDPML---TTCGTLVYAAP--------------EIIQEKPYNGMKA----DIWSAGVVLYAMVAAHFPWIVPDDM
          . ||.|||||.. ..|       |.|||. |.||              |.| . .| . .     |||| ||..| |     |   ... 
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCY-DQQCSPASDIWSLGVIMYYMLCGCPPFDCECED

-PPENIMKETARQIVEGDI-ALP----DG---ISYELQNLMANLLNVDPNERPTAAEVLEHPWF
   ||. ||. . |  ||.  ..    .|   || |. ..  ....|||. | .|.| |||.|.
RDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase 85686.m00167.AA Ciliate-E2-Unclassified 7-266 22 5e-64 219.04 In-house 1-352 (352) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-352/352
Sequence Identity: 22% (80 aa)

YEPRRFLGAGSFGGVWECQNKTTGESV-----ACKLIDLNTALSDKVYPHFRNEILIHSKIN-------------------HPSVTQLKDVILDNDNVYI
|.  . .| |.|| |..||.| ..  .     ..| .. .  .  ..   . ||...  ...                   || .  . ..  | .|.||
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

FLELCDGGDMNDIVQEFGG-----------------LSEDEAE-----HYFHQIMEALSYIHKLG-VAHRDVKLENILVTADD---DAKLTDFGLCK---
 .|.|.|||. .. .....                 ..| .|      .|| || ..|.|.|. . . ||| |.||||.. .      |..|||..|   
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

-------------QQHGNDPMLTTCGTLVYA----APEIIQEKPYNGM---KADIWSAGVVLYAMVAAHFPWIVPDDMPPE-------------NIMKET
             |.  .. | |.|||. |     |||..|.. |...   |.|||| ||.||.|.   .|   ...   .             .. .. 
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

ARQIVEGDIALP----DGISYELQNLMA----NLLNVDPNERPTAAEVLEHPWF
  .... . . .    ...| | ...       .|...||.|.|. ..|.||||
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 85686.m00167.AA ULK 7-266 28 1e-62 214.64 In-house 1-329 (329) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-329/329
Sequence Identity: 28% (94 aa)

YEPRRFLGAGSFGGVWECQNKTT----GESVACKLIDLNTALSDKVYPH-------FRNEILIHSKIN--------HPSVTQLKDVILDN--DNVYIFLE
|. .. || |||| | .  || |    .| |||| ||...   ..           ..||| |  |..        || . .|.|.  .   .|.||..|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LCDGGDMNDIVQEFGG----------LSEDEAEHYFHQIMEALSYIHKLGVAHRDVKLENILVTAD----DD--------AKLTDFGLCKQ-QHG---ND
.|.|||  .. .. ..          |||.|| ..|.||.... ..|| .. ||| |..|||.. .    |.        .|..|||..|. . .   ..
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

PMLTTC------GTLVYAAPEIIQ----EKPYNGMKADIWSAGVVLYAMVAAHFPWIVPDDMPPE-NIMKETARQ-------IVEGDIALPDG-----IS
 |.|.       ||  | ||.|.|    .|||.  |.|||| |...| |.    |.  .  ..   .|...  ..       |    .  |.      ||
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

YELQNLMANLLNVDPNERPTAAEVLEHPWF
 |...|   .| .|...| .  |...||||
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 85686.m00167.AA STE 7-266 24 3.2e-60 206.39 In-house 1-359 (359) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-359/359
Sequence Identity: 24% (89 aa)

YEPRRFLGAGSFGGVWECQNKT---------------TGESVACKLIDLNTALS--------------DKVYPHFRNEILIHSKIN--HPSVTQLKDVIL
.|  ...| |.|| |  . |.                ||| .| | ..|..  .              ..    . .|| |..| |  || . .  .  .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DN-------DNVYIFLELCDGGDMNDIVQ---EFGG-----------LSEDEAEHYFHQIMEA-LSYIHKLGVAHRDVKLENILVTADDDAKLTDFGLCK
..       |...|..|..|||   ||..   . |.           ..|..  .. .|| .. |.|.|.... |||.|  |||.     .||.|||.|.
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

QQHG----------------NDPML-TTCGTLVYAAPEIIQE------KPYNGMKADIWSAGVVLYAMVAAHFPWIVPDDM-PPENIMKE--------TA
|                   .. .  | .||  . |||.||       |.| . |.|||| | ..  |.  . ||    .|    .|...          
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGY-DTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

RQIVEGDIA-LPDGIS-------------------YELQNLMANLLNVDPNERPTAAEVLE--HPWF
 .||.|..  ||| .|                    |... ... |. |||.|||| . |.  ||..
-CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 85686.m00167.AA ULK 7-266 28 1.6e-59 204.07 In-house 1-324 (324) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-324/324
Sequence Identity: 28% (92 aa)

YEPRRFLGAGSFG-GVWECQNKTT---GESVACKLIDLN-TALSDKVYP------HFRNEILIHSKIN---HPS--VTQLKDVILDN--DNVYIFLELCD
|. .. || ||||  | .  || |   .. |||| ||..    . . ..       ..||| |  |..   ||   . .|.|.  .   .|.||..|.|.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGDMNDIVQEFGG---------LSEDEAEHYFHQIMEALSYIHKLGVAHRDVKLENILVTADDD------------AKLTDFGLCKQ-QHGN---DPMLT
|||  .. .. ..         |||.|| ..|.||.... ..|| .. ||| |..|||.. ..             .|..|||..|. . .|   . . |
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

TC------GTLVYAAPEIIQ----EKPYNGMKADIWSAGVVLYAMVAAHFPWIVPDDMPPE-NIMKETARQ-------IVEGDIALPD-----GISYELQ
..      ||  | ||.|.|    .|||.  |.|||| |...| |.    |.  .  .. . . ...  ..       |    |  |.      || |..
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECK

NLMANLLNVDPNERPTAAEVLEHPWF
.|   .| .|...| .  |...||||
DLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 85686.m00167.AA TyrKc 7-266 22 1.3e-15 29.55 SMART 1-280 (280) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

YEPRRFLGAGSFGGVWECQNKTTGESVACKLIDLNTALSDKVYPHFRNEILIHSKI--NHPSVTQLKDVILDN-------DNVYIFLELCDGGDMNDIVQ
 .  . || | || |.... |   . || | .  ..         |..|. | .|.  .|| . .|  |...        . ..| .|....|| .|  .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

EFGG-LSEDEAEHYFHQIMEALSYIHKLGVAHRDVKLENILVTADDDAKLTDFGLCKQQHGN------DPMLTT----CGT--LVYA--APEIIQEKPYN
. .. |. ..  .. .|| .  .|.|. .. |||    |.||...  .| .||||..  .        . . ..    .|   | .   ||| |... ..
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

GMKADIWSAGVVLYAMVA-AHFPWIVPDDMPPENIMKETARQIVEG-DIALPDG--------ISYELQNLMANLLNVDPNERPTAAEVLEHPWF
  | |.|| ||... .      |.  .  .      .|  ... .|     |.          . |. ..|    . ||..||| .|.  |  |
-TKSDVWSFGVCMWEIFTYGQQPYPGMIQQ--MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 85686.m00167.AA Pkinase_Tyr 7-153 25 1.8e-08 29.3 Pfam 1-159 (270) Show / Hide 
Range on Protein: 7-153
Range on HMM: 1-159/270
Sequence Identity: 25% (41 aa)

YEPRRFLGAGSFGGVWECQNK----TTGESVACKLIDLNTALSDK-VYPHFRNEILIHSKI-NHPSVTQLKDVIL-DNDN--VYIFLELCDGGDMNDIVQ
 .  . ||.|.|| |...  |     |.  || | .  ..| ..      | .|. | ... .|| . .|  |.. . .   .|| .|.. .||. |  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

E----FGGLSEDEAEHYFHQIMEALSYIHKLGVAHRDVKLENILVTADDDAKLTDFGLCK
.     . |.  .  .. .|| ....| .  .  |||.   |.||| .  .| .||||..
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR