Gene 94173.m00183 (T.vaginalis)

94173.m00183

Species: T.vaginalis
Alias: 94173.m00183, TvagK0689
External Links:
Annotation:

Classification

Group: Other
Family: NEK
Subfamily: NEK1

Sequence

Name Sequence Type Origin Length Description Download
94173.m00183.AA Protein None 462 None Fasta, JSON
94173.m00183.kin_dom Protein Kinase Domain None 255 None Fasta, JSON

Protein domain

Protein domains of 94173.m00183.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 94173.m00183.AA NEK 4-258 45 1.7e-138 466.42 In-house 1-286 (286) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-286/286
Sequence Identity: 45% (130 aa)

YEVIKCIGEGSFGKALLVKHIESQEL-----RVIKQVDLSQQNETIQEASL-RESNLLSELDHPNIIRFYDSFLEGD--VLCTVMEYAA-GGDIASK---
||.|| ||.|||||. .|.... .        |.|.....  .|  .....  | ..|..|.||||...||||.| .   || ||||.  ||| . |   
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

IAEAK--GMHFPEFVIISWFAQMCLGLQYIHSH-----HILHRDIKSQNIFLDADGN----VKIGDFGTAKCLEETGEFAET-VVGSPFYLSPEICQGVP
| . |  | .|.| .|  ||.||||.|.|.|..     .|||||||.|||||....|    ||||||| .| |. | ..| | .|| | |.|||.||. |
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKP

YNAKTDIWSLGCVLYELCTLVP--AFSGD--CIGGIVMKILRS-EQPPIPGE--YSSDLSNLVDSMLQKNPCRRPTITQILSLSFL
|| | |||||||||||.||| |  .| ..   . . .||| .  . ||||    ||.||.||. .||||.|  ||...|||...|.
YNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase 94173.m00183.AA NEK1 4-258 47 4.5e-132 445.07 In-house 1-276 (276) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-276/276
Sequence Identity: 47% (132 aa)

YEVIKCIGEGSFGKALLVKHIESQELRVIKQVDLSQQNETIQEASLRESNLLSELDHPNIIRFYDSFLEGDV--LCTVMEYAAGGDIASKIAEA--KGMH
|..|| |||||||||.|||| |.  . |||   .... |   |.|..| ..|. ..||||.....|| |.    |  ||||. |||.. || ..  ||  
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGKL

FPEFVIISWFAQMCLGLQYIHSHHILHRDIKSQNIFLD--ADG---------------NVKIGDFGTAKCLEETGEFAETVVGSPFYLSPEICQGVPYNA
|.|. | .|| |.||.|..||.  |||||||||||||    .|                ||.||||.|. | .| |.| |..| | ||||||||  ||| 
FSEDQIMHWFCQICLALNHIHDRKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPEICQNKPYNN

KTDIWSLGCVLYELCTLVPAFSGDCIGGIVMKILRSEQPPIPGEYSSDLSNLVDSMLQKNPCRRPTITQILSLSFL
|.|||||||||||||||  .| .      |.||...  ||||  || .|..|| .|...||  || ..|||.  |.
KSDIWSLGCVLYELCTLKHPFEANNWKNLVLKICQGTYPPIPPHYSYELQSLVSQMFKRNPRHRPSVNQILERPFI
Kinase 94173.m00183.AA NEK8 4-258 37 1.2e-113 325.88 In-house 1-278 (278) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-278/278
Sequence Identity: 37% (105 aa)

YEVIKCIGEGSFGKALLVKHIESQ--ELRVIKQVDLSQQNETIQEASLRESNLLSELDHPNIIRFYDSFLEGDVLCTVMEYAAGGDIASKIAEAKG-MHF
|| |  .| |.|| . |    | |   | ..||.....  |    . . | ..|| |.|||||  ||.|.|  .|  .|||| ||  . .|.. ..  ..
YERIRVVGRGAFGICWLYRRKEDQSHHLVIWKQINMHRMSEKERQMAQNEIQVLSMLQHPNIISYYDHFMEDNTLMIEMEYADGGTLYQMIQHQQNKLFE

PEF----------------VIISWFAQMCLGLQYIHSHHILHRDIKSQNIFLDAD-GNVKIGDFGTAKCLEETGEFAE--TVVGSPFYLSPEICQGVPYN
.|                  |.  | |||... ..|.| |||||.| ||||.. . . ||||||| .| .      ..  |||| | |.|||.|.|.|||
EERQLKQVNHCFNIYFNEQMILWYFFQMCSAVHHMHQHNILHRDLKTQNIFMTRHRMVVKIGDFGISKIMNTKYHMQTTKTVVGTPYYMSPEMCEGKPYN

AKTDIWSLGCVLYELCTLVPAFSGDCIGGIVMKILRS-EQPPIPGEYSSDLSNLVDSMLQKNPCRRPTITQILSLSFL
.| |.|.|||||||.|.|  || ..    .|.|| .. .. ||.. ||...  || . ||. | .||.  ||..   .
QKSDMWALGCVLYEMCCLKRAFEASNLPALVWKIMQCRAYEPISDHYSNEMRMLVHNCLQQDPEQRPSASQIMAMPLC
Kinase 94173.m00183.AA S_TKc 4-258 32 1.9e-92 314.33 SMART 1-231 (231) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-231/231
Sequence Identity: 32% (87 aa)

YEVIKCIGEGSFGKALLVKHIESQELRVIKQVDLSQQNETIQEASLRESNLLSELDHPNIIRFYDSFLEGDVLCTVMEYAAG--GDIASKIAEAKGMH--
||... ||.|.|||  ...|......  ||...         |  .|| ..|.. .||||...||.| . | |. ||||. |  ||  . | . ..    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--FPEFVIISWFAQMCLGLQYIHSHHILHRDIKSQNIFLDADGNVKIGDFGTAKCLEETGEFAETVVGSPFYLSPEICQGVPYNA-KTDIWSLGCVLYEL
  ||| .. ....|.|..|.|.|||.|.|||.| .||.||   ..||.||| |. |        |..|.|.|..||..   .|.  | |.||.||.|||.
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

CTLVPAFSGDCIGGIVMKILRSEQPPIPGEYSSDLSNLVDSMLQKNPCRRPTITQILS-------LSFL
..  | |.   .  .  ||.           |... .... .|||.| .|||. ..|          ..
LCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 94173.m00183.AA NEK4 4-258 39 2e-88 300.06 In-house 1-257 (257) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-257/257
Sequence Identity: 39% (101 aa)

YEVIKCIGEGSFGKALLVKHIESQELRVIKQVDLSQQNETIQEASLRESNLLSELDHPNIIRFYDSFLEGDV--LCTVMEYAAGGDIASKIAEAKGMHFP
|. .| .| ||.|   ||.|       |.| ..| .     . | ..| .||| | ||||. . .|.  ..   |. || .  |||   |  . |.   .
YCHMKVVGKGSYGEVWLVRHRRDKKQYVMKKMFLKNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDLYRKLKQQKNQFLE

EFVIISWFAQMCLGLQYIHSHHILHRDIKSQNIFLDADGNVKIGDFGTAKCLEETGEFAETVVGSPFYLSPEICQGVPYNAKTDIWSLGCVLYELCTLVP
|  .. || |  ..|||.|  |||||| | |||||     .|||||| .. |.. ...|.|..| |.|.|||.    ||. | ||||||| .||. ||  
EYQVVEWFVQIAMALQYMHEKHILHRDLKTQNIFLTKKNIIKIGDFGISRVLNNHCDMAKTMIGTPYYMSPECFGNRPYDYKSDIWSLGCCVYEMITLKH

AFSGDCIGGIVMKILRSEQPPIPGEYSSDLSNLVDSMLQKNPCRRPTITQILSLSFL
||    .  .. .|.    ||.| .|| || |||  ||.| | .|| | .|.   ..
AFDAKDMNSLIYQIIQGQPPPMPPNYSQDLQNLVYQMLEKQPTKRPSIFDIFQMPYI
Kinase 94173.m00183.AA Pkinase 4-258 28 5.1e-88 303.52 Pfam 1-293 (293) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-293/293
Sequence Identity: 28% (84 aa)

YEVIKCIGEGSFGKALLVKHIESQELRVIKQVDLSQQNETIQEASLR--ESNLLSELDHPNIIRFYDSFLEGDVLCTVMEYAAGG----DIASKIA--EA
|.....||.||||.  . .|. .... ..|..... ...  ... .|  |  .. .|.||||.|.||.| ..| .. ||||. ||    | .. |   . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KGMHFPEFVIISWFAQMCLGLQYIHSHHILHRDIKSQNIFLDADGNV----KIGDFGTAKCL-EETGEFAETVVGSPFYLSPEICQ-GVPYNAKTDIWSL
... |.| ...... |.. ||.|.||. |.|||.|..||..| .|..    ||.||| ||.. .  .. . |..|.|.|..||... | .|  | |.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCVLYELCTLVPAFSGD------CIGGIVMKILR-----SEQPPIPGEYS---------------SDLSNLVDSMLQKNPCRRPTITQILSLSFL
||.|||...  | |.|.      .   .. .|..     ... .... |.               ...  .....|.|.| .|||..|||   ..
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 94173.m00183.AA STE 4-258 25 5e-74 252.24 In-house 1-359 (359) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-359/359
Sequence Identity: 25% (93 aa)

YEVIKCIGEGSFG---KALLVKHI---ESQEL---------RVIKQVDLSQQN---------------ETIQEASLRESNLLSELD--HPNIIRFYDSFL
.| |..||.|.||   ||. .| .   ...|.           |||..|...|               .....  |.| .......  ||||...|....
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EG-------DVLCTVMEYAAGGDIASKIAEAKGM------------HFPEFVIISWFAQMCLG-LQYIHSHHILHRDIKSQNIFLDADGNVKIGDFGTAK
 .       | |. .||| .|| . . | . .|.            .||| .|.    | . | |.|.||||| |||||..||.|     ||. |||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

CLEE----------------TGEFAETVVGSPFYLSPEICQG------VPYNAKTDIWSLGCVLYELCTLVPAFSGDCIGGIVMKILRS-----------
.|..                ...   |.||.| . .||. |.       .|..| |||||||.. |..|  | ..        . |...           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---EQPP-IPG-------------------EYSSDLSNLVDSMLQKNPCRRPTITQILS--LSFL
   ..|| .|                    ..|... . ..  |||.|  ||| .| |.   .|.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 94173.m00183.AA CAMK 9-258 20 4.8e-73 234.5 In-house 1-425 (425) Show / Hide 
Range on Protein: 9-258
Range on HMM: 1-425/425
Sequence Identity: 20% (89 aa)

CIGEGSFGKALLVKHIESQ------------ELRVIKQVDLSQQN--------------------------ETIQEASLRESNLLSE-------LDHPNI
 .|.|||||  |..|....            .   || .| ..                            .  ..  .|| ....        ||||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IRFYDSFLEGDV-------------------LCTVM---EYAAGG----DIASKIAEAKG-------------MHFPEFVIISWFAQMCLGLQYIHSHHI
|..|. .  ...                   .. ||   ||. ||    |. ..| | ..              .|.|     .| |.| ...|.|||.|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

LHRDIKSQNIFLDAD-----------------GNVKIGDFGTAKCLEE-----------------------TGEFAETVVGSPFYLS-PEICQG------
 |||.|  || || .                 .|.|| ||| |. ...                       .|.  .|..|.| | . ||. .|      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------VPYNAKTDIWSLGCVLYELCTLVPAFSGD-------------CIGGIVMKILRSEQPPIPGEYSS-----------------------DLSN
         .|. |.|.||.|..|| . .  | | ||             ..  .  ||.. .   .| . |                        .  .
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LVDSMLQKNPCRRPTITQILSLSFL
|. .|||..| .|.||.|.|.  ..
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 94173.m00183.AA NEK2 4-258 31 2.8e-72 242.67 In-house 1-319 (319) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-319/319
Sequence Identity: 31% (102 aa)

YEVIKCIGEGSFGKALLVKHIESQELRVIKQVDLSQQNETIQEASLRESNLLSELDHPNIIRFYDSFL--EGDVLCTVMEYAAGGDIASKIAEAKGMH--
||| . ||.||||.   |....  .. | |  .  . .|    .   | |.|..| ||||.|.||     .  .|  |||| .||| .. |  ..  .  
YEVLYTIGNGSFGRCRKVRRKSDGKILVWKEICYGHMQEKECQMLVSECNILRQLKHPNIVRYYDWIIDRQNSTLYIVMEYCEGGDLSQMIKKCRKERQY

FPEFVIISWFAQMCLGLQYIHS---------------------HHILHRDIKSQNIFLDADGN-------------------------------------
..| .|   ..|.|. || .|                      | |||||||  |||||.|.|                                     
MEEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGKHTILHRDIKPANIFLDYDHNDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQ

--VKIGDFGTAKCLEETGEFAETVVGSPFYLSPEICQGVPYNAKTDIWSLGCVLYELCTLVPAFSGDCIGGIVMKILRSEQPPIPGEYSSDLSNLVDSML
  || |||| |. |.    || | || |.| |||  .| .|| | ||||.||..||.|.| | | .        ||   .  .||  ||..|. .. .|.
VVVKLGDFGLARMLNHDTSFAHTFVGTPYYMSPEQMHGQKYNEKSDIWSVGCLIYEMCALHPPFQATNQAQLQEKIKQGHFRRIPYQYSRHLNEIIHFMI

QKNPCRRPTITQILSLSFL
  ..  || |  ||  ...
NVDHYHRPSIEEILQHPQI
Kinase 94173.m00183.AA NEK-Unclassified 4-258 35 7.3e-70 230.41 In-house 1-258 (258) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-258/258
Sequence Identity: 35% (93 aa)

YEVIKCIGEGSFGKALLVKHIESQELRVIKQVDLSQQNETIQEASLRESNLLSELDHPNIIRFYDSFLEGDVLCTVMEYAAGGDIASKIAEAKGM--HFP
|. |  .| |  |   ||.|  |.   ...|.   ..    |   .    .|| | || |. . ||| |   |    .|  ||.   .|    .    | 
YDKITTLGQGGGGAVYLVRHQISKR-HLVQQISKRKKKKKRQNKII----ILSQLRHPHIVTYHDSFFENAKLFYTQDYCDGGNLDRRIQKHRKKNEPFD

EFVIISWFAQMCLGLQYIHSHHILHRDIKSQNIFLDADGNVKIGDFGTAKCLEETGEFAETVVGSPFYLSPEICQGVPYNAKTDIWSLGCVLYELCTLVP
|  |  |. ||   .||||.  |.||| | |||||  |  | .|||| .. ...| . | | ||.. ..|||.||  ||| . |.|||||..||.||  |
EGRIMQWCIQMIMAVQYIHQRKIIHRDLKPQNIFLTDDDTVSMGDFGISRIMDHTRDKARTCVGTMCWMSPEVCQDQPYNNRSDVWSLGCIIYEMCTCEP

AFSGDCIGGIVMKILRSEQ------PPIPGEYSSDLSNLVDSMLQKNPCRRPTITQILSLSFL
.|    .| . ||| . .        |.   || ||....  ||..|. .||  | |... . 
FFDTHNMGEVYMKIKQDDNRLEEALEPVSKTYSTDLQQVIRFMLRRNFQQRPSATEIVEQDYI
Kinase 94173.m00183.AA NEK11 4-258 41 7.7e-70 238.34 In-house 1-259 (259) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-259/259
Sequence Identity: 41% (110 aa)

YEVIKCIGEGSFGKALLV---KHIESQELRVIKQVDLSQ--QNETIQEASLRESNLLSELDHPNIIRFYDSFLEGDVLCTVMEYAAGGDIASKIAEAK--
| . . .| ||||   ||   |     ||.|.| .       |||.| | . |  ||| |.|| |.||  ||.| |  | . ||  | |.  .| | |  
YVLQQKLGSGSFGTVYLVSDKKAKRGEELKVLKEISVGELNPNETVQ-ANV-EAQLLSRLHHPAIVRFHASFMEQDNFCIITEYCEGRDLDYRIQEYKQA

GMHFPEFVIISWFAQMCLGLQYIHSHHILHRDIKSQNIFLDADGNVKIGDFGTAKCLEETGEFAETVVGSPFYLSPEICQGVPYNAKTDIWSLGCVLYEL
|  |||  || || |. ||  |.|   |||||.||.||||     .|||||| .. |    . | |. | | |.|||  .   | .| ||||| |.|||.
GKIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNIFLKNN-LLKIGDFGVSRLLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEM

CTLVPAFSGDCIGGIVMKILRSEQPPIPGEYSSDLSNLVDSMLQKNPCRRPTITQILSLSFL
| .  || |     ||..|   . | .|  |  .|  ....|| |||  ||   .||   ..
CCMDHAFAGSNFLSIVLNIVEGDTPSLPDRYPRELNTIMERMLNKNPSLRPSAIDILKIPYM
Kinase 94173.m00183.AA CAMKL 4-258 32 3.5e-69 219.9 In-house 1-297 (297) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-297/297
Sequence Identity: 32% (98 aa)

YEVIKCIGEGSFGKALLVKH-IESQELRVIKQVDLSQQN-ETIQEAS------------LRESNLLSELD---HPNIIRFYDSFLEGDV------LCTVM
|...| .|.|||||  | .| .  .|   || .| .  . ... ..              || .... |.   |||||..|. .   .       .. ||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYAAGGD--IASKIAEAKG--MHFPEFVIISWFAQMCLGLQYIHSHHILHRDIKSQNIFLDADG--NVKIGDFGTAKCLEE----TGEFAETVVGSPFYL
||. ||.     .| . ..    .||      | |.. ...|.|||.| |||||  || || .|  |.|| ||| .   ..    .|.. .|  ||| | 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

SPEICQG--VPYN-AKTDIWSLGCVLYELCTLVPAFSGD--------CIGGIVMKILRSEQPPIPGEYSSDLSNLVDSMLQKNPCRRPTITQILSLSFL
.|||.||   ||.  |.||||.| .|| . .    | .|        .|     || . ..|||. . | |. .|  .|||.|| .|||| ||..  ..
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCGYYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 94173.m00183.AA Pkinase_Tyr 49-148 28 6.5e-17 57.9 Pfam 51-156 (270) Show / Hide 
Range on Protein: 49-148
Range on HMM: 51-156/270
Sequence Identity: 28% (30 aa)

LRESNLLSEL-DHPNIIRFYDSFL-EGDV--LCTVMEYAAGGDIASKIAEA--KGMHFPEFVIISWFAQMCLGLQYIHSHHILHRDIKSQNIFLDADGNV
.|| .....| .||||.|.|   . .|.   .. ||||...||  .   .    . ...   .... .| . |..| .|... |||.   |. .. .. |
MREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVV

KIGDFG
||.|||
KICDFG
Kinase 94173.m00183.AA TyrKc 4-258 20 1.1e-16 47.06 SMART 1-280 (280) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-280/280
Sequence Identity: 20% (61 aa)

YEVIKCIGEGSFG---KALLVKHIESQELRVIKQVDLSQQNETIQEASLRESNLLSEL--DHPNIIRFYDSFLEG-------DVLCTVMEYAAGGDIASK
 . .| .||| ||   |. .       .   .| .  .      .|. .|| .....|  .||||.|.|   ...       . |. ||||...||  . 
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

IAEAKGMHFPEFVIISWFAQMCLGLQYIHSHHILHRDIKSQNIFLDADGNVKIGDFGTAKCLEET---GEFAETVV-----GSP-----FYLSPEICQGV
. . ..  ..    .|.  | . | .|.||... |||.   |. ..... |||.||| .. ...    ||  .. .     |.        ..||  .  
LRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

PYNAKTDIWSLGCVLYELCTLVPAFSGD-----CIGGIVMKILRSE-QPPIPGE--------YSSDLSNLVDSMLQKNPCRRPTITQILSLSFL
 .. |.|.|| | ...|..|.      .     .    |.. ...   .|.| .         .... ..  .  . .|  ||| ..|   ...
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 94173.m00183.AA Pkinase_Tyr 180-199 35 0.015529 9.21 Pfam 191-210 (270) Show / Hide 
Range on Protein: 180-199
Range on HMM: 191-210/270
Sequence Identity: 35% (7 aa)

YNAKTDIWSLGCVLYELCTL
.. |.|.|| | ...|..|.
FTTKSDVWSFGVLMWEIFTY
Kinase 94173.m00183.AA Pkinase_Tyr 4-17 42 2.019388 2.05 Pfam 1-14 (270) Show / Hide 
Range on Protein: 4-17
Range on HMM: 1-14/270
Sequence Identity: 42% (6 aa)

YEVIKCIGEGSFGK
 . .| .|||.||.
ITFGKKLGEGAFGE